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个人简介

学习/工作经历 2003.9-2006.6:中国农业大学(博士) 2006.9-2008.9:中国海洋大学(博士后) 2014.3-2014.9:美国马里兰大学(访问学者) 2008.9至今:中国海洋大学 科研/教学情况 承担课题 主持山东省自然科学基金青年和面上项目、教育部博士点新教师基金、国家“十二五”“863计划”现代农业技术领域重大项目和国家自然科学基金面上项目等课题8项,较系统地研究了鲆鲽鱼类内分泌生理机制与表观遗传调控作用;利用CRISPR-cas9基因敲除系统研究基因的功能,最终目的是通过基因转移、基因修饰等先进的分子遗传技术进行品种改良和新品系的开发,推动我国海水养殖业良种化进程,为推进海水经济鱼类苗种产业化奠定了理论和技术基础。 讲授课程 基础分子生物学

研究领域

鱼类生理与表观遗传(Epigenetics)研究鱼类基因功能(CRISPR-Cas9)和种质创新研究

近期论文

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HeFeng,Dong-xiaoSun,YingYu,Ya-chunWang,YuanZhang.PolymorphismswithinthepromoteroftheprolactingeneanditsassociationswithmilktraitsinChineseHolsteinbovine.Asian-AustralianjournalofAnimalScience,2006,19:1384-1390.SCI收录.HeFeng,WenHai-Shen,DongShuang-Linetal.IdentificationofEstrogenReceptorαGenepolymorphismsbyPCR-SSCPandItsEffectonReproductiveTraitsinJapaneseflounder(Paralichthysolivaceus).ComparativePhysiologyBiochemistryPartB.2008,150:278-283.SCI收录.HeFeng,WenHai-Shen,DongShuang-Linetal.IdentificationofSingleNucleotidePolymorphismCytochromeP450-c19aanditsRelationtoReproductiveTraitsinJapanese flounder(Paralichthysolivaceus).Aquaculture,2008,279:177-181.SCI收录.HeFeng,WenHai-Shen,DongShuang-Linetal.IdentificationofasinglenucleotidepolymorphismwithinpromoterofJapaneseflounder(Paralichthysolivaceus)ovarycytochromeP450-c19(CYP19a)anditseffectonreproductivetraits.FishPhysiologyBiochemistry.2009,35:333-340.SCI收录.HeFeng,WenHai-Shen,YuDahui,LiJifangetal.SingleNucleotidePolymorphismofFSHβGeneAssociatedwithReproductiveTraitsinJapaneseFlounder(Paralichthysolivaceus)SingleNucleotidePolymorphismofFSHβGeneAssociatedwithReproductiveTraitsinJapaneseFlounder(Paralichthysolivaceus).J.OceanUniv.China,2010:9(4):395-398.HeFeng,WenHai-Shen,LiJi-Fangetal.SingleNucleotidePolymorphismsoftheGnRHRGeneAssociatedwithReproductiveTraitsofJapaneseflounder(Paralichthysolivaceus).Asian-AustralianjournalofAnimalScience.2011.SCI收录.DingYu-xia,HeFeng*,WenHai-Shen,LiJi-Fangetal.PolymorphisminexonsCpGrichregionsofthecyp17-IIgeneaffectingitsmRNAexpressionandreproductiveendocrinelevelsinfemaleJapaneseflounder(Paralichthysolivaceus).GeneralandComparativeEndocrinology,2012,179(1):107-114.(SCI收录)MaRu-iqin,HeFeng*,WenHai-Shen,LiJi-Fangetal.MutationsinexonsoftheCYP17-IIgeneaffectsexsteroidconcentrationinmaleJapaneseflounder(Paralichthysolivaceus).JournalofOceanUniversityofChina,2012,11(1):99-104.(SCI收录)MaRui-qin,HeFeng*,WenHai-Shen,LiJi-Fangetal.PolymorphysimsofCYP17-IGeneintheExonsWereAssociatedwiththeReproductiveEndocrineofJapaneseFlounder(Paralichthysolivaceus).Asian-AustralasianJournalofAnimalSciences,2012,25(6):794-799.(SCI收录)DingYu-xia,HeFeng*,WenHai-Shen,LiJi-Fangetal.DNAmethylationstatusofcyp17-IIgenecorrelatedwithitsexpressionpatternandreproductiveendocrinologyduringovariandevelopmentstagesofJapaneseflounder(Paralichthysolivaceus).Gene,2013,527(1):82-88.(SCI收录)ZhaoJun-li,HeFeng*,YufengSi,WenHai-Shen,LiJi-Fangetal.PolymorphismsandDNAmethylationlevelintheCpGsiteoftheGHR1geneassociatedwithmRNAexpression,growthtraitsandhormonelevelofhalf-smoothtonguesole(Cynoglossussemilaevis).FishPhysiologyandBiochemistry,2015,41(4):853-865.(SCI收录)LiSi-ping,HeFeng*,WenHai-Shen,LiJi-Fangetal.AnalysisofDNAmethylationlevelbymethylation-sensitiveamplificationpolymorphisminhalfsmoothtonguesole(Cynoglossussemilaevis)subjectedtosalinitystress.JournalofOceanUniversityChina(2016).doi:10.1007/s11802-017-3156-4.(SCI源期刊) SiYu-feng,DingYu-xia,HeFeng*,WenHai-Shen,LiJi-Fangetal.DNAmethylationlevelofcyp19a1aandFoxl2generelatedtotheirexpressionpatternsandreproductiontraitsduringovarydevelopmentstagesofJapaneseflounder(Paralichthysolivaceus).Gene,2016,575(2,Part1):321-330.(SCI收录)SiYu-feng,HeFeng*,WenHai-Shen,LiJi-Fangetal.GeneticpolymorphismsandDNAmethylationinexon1CpG-richregionsofPACAPgeneanditseffectonmRNAexpressionandgrowthtraitsinhalfsmoothtonguesole(Cynoglossussemilaevis).FishPhysiologyandBiochemistry.2016,42(2):407-421.(SCI收录)

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