个人简介
1975: B. Pharm. (Honours) in pharmacy, The School of Pharmacy, University of London
1976: M.R.Pharm.S. Member of the Royal Pharmaceutical Society of Great Britain (undertaken within the Oxford Regional Health Authority)
1979: M. Sc. in pharmacology with toxicology, University of East London (formerly the North East London Polytechnic)
1989: Ph. D. in Pharmacognosy, (Antiamoebic and antimalarial natural products), The School of Pharmacy, University of London
2008-2011: Head of Division of Pharmaceutics and Pharmaceutical Chemistry
2004-present: Reader in Pharmacognosy, The School of Pharmacy, University of Bradford
2002-present: Honorary Senior Lecturer in Pharmacognosy, The School of Pharmacy, University of London
2001-2004: Senior lecturer in Pharmacognosy, the School of Pharmacy, University of Bradford
1994-2001: Lecturer in Pharmacongosy, The School of Pharmacy, University of Bradford
1993-2002: Honorary Lecturer in Pharmacognosy, The School of Pharmacy, University of London
1992–1993: Research Fellow The School of Pharmacy, University of London
1993–1993: Lecturer in Pharmacognosy at The School of Pharmacy, University of London
1993-1994: Appointed by Pharmakon (Australia) initially on a consultancy basis (July-August 1993) to provide scientific advice and facilitate the licensing of Pharmakon products as medicines in the U.K. In addition I undertook various administrative tasks including the formation of a new company (Pharmakon U.K.). From September 1993-April 1994 I was employed by the sister company Pharmakon (USA) Inc. in a scientific capacity to liaise with the Medicines Control Agency in London and work towards product licensing.
1989–1992: Maplethorpe Research Fellow in the Department of Pharmacognosy, The School of Pharmacy, University of London
1984–1985: Locum grade 1 pharmacist at Oldchurch Hospital, Romford, Essex. Duties in clinical services with an emphasis on clinical pharmacy. Frequently acting grade 2 pharmacist (in charge) at Rush Green Hospital, Romford, Essex
1982-1984: Studied theology and mission at All Nations Christian College, Ware, Herts. Communications was an important element of the course. Obtained the All Nations Christian College Diploma, and completed half the papers for the Cambridge Diploma in Religious Studies
1980-1982: Voluntary work in India for the Emmanuel Hospital Association, a Christian organisation responsible for 17 hospitals in North India aimed at providing rural health care. The work involved upgrading and developing pharmacy services at Herbertpur Christian Hospital, Dist. Dehra Dun, U.P. and the promotion of the cost-effective and rational use of medicines. Duties included dispensing to outpatients and inpatients, preparation of intravenous fluids, eye drops, mixtures, ointments etc. Also visited some of the other hospitals run by the organisation to give advice and assistance with pharmaceutical matters. During this time compiled "A guide to Drugs and Therapeutics", a publication designed to provide information for medical and nursing staff and to encourage rational prescribing of drugs and medicines
1980: Locum grade 1 pharmacist at the Royal Free Hospital, Hampstead
1978-1980: Pharmacist with the Boots Company. Dispensary manager and locum pharmacist in community pharmacies in East London
1976-1978: Grade 1 Pharmacist at King George Hospital, Ilford, Essex, and acting pharmacist in charge when required
1975–1976: Pre-registration pharmacist, Oxford Regional Health
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Olajide, O., Heiss, E.H., Schachner, D., Wright, C.W., Vollmar, A.M. and Dirsch, V.M. Synthetic cryptolepine inhibits DNA binding of NF-κB. Bioorganic and Medicinal Chemistry 15:43-49, 2007
Watjen, W., Kulawik, A., Suckow-Schnitker, Chovolou, Y., Rohrig, R., Ruhl, S., Kampkotter, A., Addae-Kyereme, J., Wright, C.W. and Passreiter, C.M. Pterocarpans phaseollin and neorautenol isolated from Erythrina addisoniae induce apoptotic cell death accompanied by inhibition of ERK phosphorylation. Toxicology 242:71-79, 2007
Kantamreddi, V.S.S. and Wright, C.W. Investigation of Indian Diospyros species for antiplasmodial properties. eCAM (Electronic Complementary and Alternative Medicine), doi:10.1093/ecam/nem019, 2007
Seville, S., Phillips, R.M.,Shnyder,S.D.and Wright, C.W. Synthesis of cryptolepine analogues as potential bioreducible anticancer agents. Bioorganic and Medicinal Chemistry 15:6353-6360, 2007
Bayor, M.T., Ayim, J.S.K., Phillips, R.M.,Shnyder,S.D.and Wright, C.W. The evaluation of selected Ghanaian medicinal plants for cytotoxic activities. Journal of Science and Technology 27:16-22, 2007
Ajaiyeoba, E.O., Ashidi, J.S., Okpako, L.C., Houghton, P.J. and Wright, C.W. Antiplasmodial compounds from Cassia siamea stem bark extract. Phytotherapy Research, 22:254-255, 2008
Watjen, W., Suckow-Schnitker, A.K., Rohrig, R., Kulawik, A., Addae-Kyereme, J., Wright, C.W. and Passreiter, C.M. Prenylated flavonoid derivatives from the bark of Erythrina addisoniae. Journal of Natural Products 71:735-738, 2008
Lisgarten, J.N., Potter, B.S., Pitts, J.E. Palmer, R.A. and Wright, C.W. Structure of the antiplasmodial compound 7, 9-dinitrocryptolepine hydrochloride methanol solvate. Journal of Chemical Crystallography 38:807-813, 2008
Potter, B.S., Lisgarten, J.N., Pitts, J.E., Palmer, R.A. and Wright, C.W. X-ray crystallographic structure of the potent antiplasmodial compound 2,7-dibromocryptolepine acetic acid solvate. Journal of Chemical Crystallography 38:821-825, 2008
Bayor, M.T., Ayim, J.S.K., Marston, G., Phillips, R.M., Shnyder, S.D., Wheelhouse, R.T. and Wright, C.W. A cytotoxic diterpenoid from Croton membranaceus, the major constituent of anticancer herbal formulations used in Ghana. Natural Product Communications 3:1875-1878, 2008
Rojas, M., Wright, C.W., Pina, B., and Portugal, J. Genomewide expression profiling of the cryptolepine-induced toxicity in Saccharomyces cerevisiae. Antimicrobial Agents and Chemotherapy 52:3844-3850, 2008
Laryea, D., Isaksson, A., Wright, C.W., Larsson, R. and Nygren, P. Characterisation of the antitumour activity of the indoloquinoline alkaloid cryptolepine in human tumour cell lines and primary cultures of tumour cells from patients. Investigational New Drugs 27:402-411, 2009
Oluwafemi, A.J., Okanla, O., Camps, P., Munoz-Torrero, D., Mackey, Z.B., Chiang, P.K., Seville, S. and Wright, C.W. Evaluation of cryptolepine and huperzine derivatives as lead compounds towards new agents for the treatment of human African Trypanosomiasis. Natural Product Communications, 4:193-198, 2009
Olajide, O. A., Ajayi, A.A. and Wright, C.W. Anti-inflammatory properties of cryptolepine. Phytotherapy Research, 23:1421-1425, 2009
Kantamreddi, V.S.S., Parida, S., Kommula, S.M. and Wright, C.W. Phytotherapy used in Orissa State, India, for treating malaria. Phytotherapy Research, 23:1638-1641, 2009
Maregesi, S., Van Miert, S., Pannecouque, C., Feiz-Haddad, M.H., Hermans, N., Wright, C.W., Vlietinck, A.J., Aspers, S. and Pieters, L. Screening of Tanzanian medicinal plants against Plasmodium falciparum and human immunodeficiency virus. Planta Medica, 76:195-201, 2010
Wright, C.W., Linley, P.A., Brun, R., Wittlin, S. and Hsu, E. Ancient Chinese Methods are remarkably effective for the preparation of artemisinin-rich extracts of Qing Hao with potent antimalalarial activity. Molecules, 15:804-812, 2010
Prakasa Rao, T.S., Sarma, N.S., Murthy, Y.L.N., Kantamreddi, V.S.S.N., Wright, C.W. and Parameswaran, P.S. New polyhydroxy sterols from the marine sponge Callyspongia fibrosa (Ridley & Dendly). Tetrahedron Letters, 51:3583-3586, 2010
Defaux, J., Sala, M., Formosa, X., Galdeano, C. Taylor, M., Alobaid, W.A.A., Kelly, J.M., Wright, C.W., Camps, P., and Munoz-Torrero, D. Huprines as a new family of dual acting trypanocidal-antiplasmodial agents. Bioorganic and Medicinal Chemistry, 19:1702-1707, 2011
Sengupta, A., Chowdhury, S., Bose-Dasgupta, S., Wright, C.W., and Majumder, H.K. Cryptolepine-induced death of Leishmania donovani promastigotes is augmented by inhibition of authophagy. Molecular Biology International, Article ID 187850, 2011
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