龙红岸 - 中国海洋大学

个人简介

进化基因组学实验室Laboratory of Evolutionary Genomics负责人承担课题第15批国家“青千”（2019-2022）山东省“泰山学者”青年项目（2019.1-2024.1）国家自然科学基金面上项目（31872228; 2019.1-2022.12）中央高校基本科研业务费（2018.1-2021.1）中国海洋大学“筑峰人才计划”启动经费（2018.9-2021.8）奖项 2018 李氏基金会杰出创新奖 2016 美国遗传学会DeLill Nasser遗传学职业发展奖

研究领域

以微生物为主要研究对象，利用组学、分子遗传学和细胞生物学方法，结合种群遗传学与微生物学理论，聚焦微生物的基因组突变以及行为的进化生物学研究，具体研究方向如下：A. 原生动物的表型可塑性与适应性演化；B. 海洋微生物的基因组进化以及稳定性机制；C. 微生物环境胁迫下的突变形成；D. 医疗及环境水体中病源微生物的抗药性演化；E. 原生动物生殖方式的调控与演化。

近期论文

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Long*, H.; Miller, S.F.; Williams, E.; Lynch, M. 2018. Specificity of the DNA mismatch repair system (MMR) and mutagenesis bias in bacteria. Molecular Biology and Evolution35(10):2414–2421.Long, H.; Sung#, W.; Kucukyildirim#,S.; Williams,E.; Miller, S.;Guo, W.; Patterson, C.; Gregory, C.; Strauss, C.; Stone, C.; Berne, C.; Kysela, D.; Shoemaker, W.; Muscarella, M.; Luo, H.; Lennon, J.; Brun, Y.; Lynch*, M. 2018. Evolutionary determinants of genome-wide nucleotide composition. Nature Ecology and Evolution2: 237-240.Strauss, C.; Long*, H.; Patterson, C.; Te,R.; Lynch, M. 2017. Genome-wide mutation rate response to pH change in the coral reef pathogen Vibrio shiloniiAK1. mBio8 (4): e01021-17Long, H.; Miller, Samuel F; Strauss, Chloe; Zhao, Chaoxian; Cheng, Lei; Ye, Zhiqiang; Griffin, Katherine; Te, Ronald; Lee, Heewook; Chen, Chi-Chun; Lynch*, Michael. 2016. Antibiotic treatment enhances thegenome-wide mutation rate of target cells. Proceedings of the National Academy of Sciences U.S.A.113(18): E2498-E2505Long*, H.; Kucukyildirim#, Sibel; Sung, Way; Williams, Emily; Lee, Heewook; Ackerman, Matthew; Doak, Thomas G; Tang, Haixu; Lynch, Michael. 2015. Background mutational features of the radiation-resistant bacterium Deinococcus radiodurans. Molecular Biology and Evolution32(9): 2383-2392 Long*, H.; Sung, Way; Miller, Samuel F; Ackerman, Matthew S; Doak, Thomas G; Lynch, Michael. 2015. Mutation rate, spectrum, topology, and context-dependency in the DNA mismatch repair-deficient Pseudomonas fluorescensATCC948. Genome Biology and Evolution7(1): 262-271Farlow*, Ashley; Long#, H.; Arnoux, Stéphanie; Sung, Way; Doak, Thomas G; Nordborg, Magnus; Lynch, Michael. 2015. The spontaneous mutation rate in the fission yeast Schizosaccharomyces pombe. Genetics201(2):737-744Long*, H.; Paixão, Tiago; Azevedo, Ricardo BR; Zufall, Rebecca A. 2013. Accumulation of spontaneous mutations in the ciliate Tetrahymena thermophila. Genetics195(2): 527-540Long*, H.; Zufall, R.A. 2010. Diverse modes of reproduction in the marine free-living ciliate Glauconema trihymene. BMC Microbiology10(1): 108