Rattray, Marcus - University of Bradford

个人简介

BSc Biochemistry, 1984, University of Leeds PhD Biochemistry, 1987, University of London Feb 2013 – Dec 2016 Visiting Senior Research Fellow, Reading School of Pharmacy Jan 2008- Dec 2013 Visiting Senior Research Fellow, King’s College London, Wolfson Centre for Age- Related Diseases, Guy’s Hospital Campus, London Jan 2008 – Feb 2013 Reader in Pharmacology, Reading School of Pharmacy. University of Reading. (Oct 2011- Jan 2013 as Director of Research, Sept 2009 - Aug 2012 as Director of Pharmacology and Therapeutics, Mar 2008 to Sept 2009 as Director of Therapeutics) Oct 2006- Feb 2007 Winston Churchill Memorial Trust Fellow. Travelling in USA, Australia and Singapore to explore the question “how best to treat drug abusers” Aug 1998- Dec 2007 Senior Lecturer in Biochemistry, King’s College London, Wolfson Centre for Age-Related Diseases, Guy’s Hospital Campus Oct 1997- July 1998 Senior Lecturer in Biochemistry, UMDS, University of London Oct 1989- Sept 1997 Lecturer in Biochemistry, Division of Biochemistry and Molecular Biology, United Medical and Dental Schools of Guy’s & St Thomas’ Hospitals (UMDS), University of London Feb 1988- Sept 1989 Visiting Fellow, Gene Neuroscience Unit,National Institute on Drug Abuse, NIH, Addiction Research Center, Baltimore, USA

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Ugbode CI, Hirst WD, Rattray M. (2014) Neuronal influences are necessary to produce mitochondrial co-localization with glutamate transporters in astrocytes. J Neurochem. 130:668-67 Leoni G, Rattray M, Fulton D, Rivera A, Butt AM. (2014) Immunoablation of cells expressing the NG2 chondroitin sulphate proteoglycan. J Anat. 2014 224:216-27 Hoppe JB, Rattray M, Tu H, Salbego CG, Cimarosti H (2013) SUMO-1 conjugation blocks beta-amyloid-induced astrocyte reactivity. Neurosci Lett (546:51-6) Rendeiro C, Vauzour, D Rattray M, Waffo-Téguo P, Mérillon J-M, Butler LT, Williams CM, Spencer JPE (2013) Dietary Levels of Pure Flavonoids Improve Spatial Memory Performance and Increase Hippocampal Brain-Derived Neurotrophic Factor. PLOSone 8. e63535 Vauzour, D, Rattray M, Williams RJ and Spencer JPE (2013). Potential neuroprotective actions of dietary flavonoids. In Handbook of natural products (in press) Bahia P, Pugh, V, Hoyland K, Henlsey V, Rattray M and Williams RJ (2012) Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activity. Journal of Neurochemistry 123:182-91 Vauzour D, Spilsbury A, Vafeiadou K, Rattray M and Spencer JPE (2012) Modulation of neuroinflammation by dietary flavonoids. In Neuroinflammation: pathogenesis, mechanisms and their management Ed Carmelina Gemma. Nova Science Publishers (in press) Rendeiro C, Vauzour D, Kean RJ, Butler LT, Rattray M, Spencer JPE and Williams CM (2012) Blueberry-supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young animals. Psychopharmacology 223:319-330 Rattray M (2012) New insights on regulation of LMTK2, a membrane kinase integrating pathways central to neurodegeneration. Journal of Neurochemistry 121:327-8 Carbone M, Duty S and Rattray M Riluzole neuroprotection in a parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation (2012). BMC Neuroscience 13:38 Spilsbury A, Vauzour D, Spencer JP, Rattray M (2012) Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations. Biochem Biophys Res Commun. 418:578-83 Carbone M, Duty S and Rattray M (2012) Riluzole elevates GLT-1 activity and levels in striatal astrocytes. Neurochemistry International 60:31-38 Rainey-Smith S, Andersson D, Williams RJ & Rattray M (2010) Tumour necrosis factor alpha induces rapid reduction in AMPA receptor-mediated calcium entry in motor neurones by increasing cell surface expression of the GluR2 subunit: relevance to neurodegeneration. Journal of Neurochemistry 113:692-703 Leoni G, Rattray M, Butt AM (2009) NG2 cells differentiate into astrocytes in cerebellar slices. Molecular and Cellular Neuroscience 42, 208-218 Peacey E, Miller CCJ, Dunlop J, Rattray M (2009) The four major N- and C-terminal splice variants of the glutamate transporter GLT-1 form cell surface homomeric and heteromeric assemblies. Molecular Pharmacology 75, 1062-1073 Bahia P, Rattray M, Williams RJ (2008) Dietary flavonoid ( )epicatechin stimulates phosphatidylinositol 3-kinase dependent antioxidant response element activity and upregulates glutathione in cortical astrocytes. Journal of Neurochemistry 106, 2194-2204 Rainey-Smith S, Schroetke LW, Bahia P, Fahmi A, Skilton R, Spencer JPE, Rice-Evans C, Rattray M, Williams RJ (2008) Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation. Neuroscience Letters, 438, 29-33