个人简介

2005: M.Sc. in Pharmacy, Jagiellonian University of Kraków 2011: Ph.D. in Pharmaceutical Sciences, Trinity College, University of Dublin 2012: Project Management Associate, Irish Institute Project Management Ireland 2015: Associate of Higher Education Academy UK, University of Bradford 2013-2014: Postdoctoral Research Fellow, Identification and Control of Critical API Characteristics for Robust Drug Product Production and Performance Solid State and Synthesis Pharmaceutical Cluster, University of Limerick. School of Pharmacy and Pharmaceutical Sciences, Trinity College, University of Dublin. 2011-2013: Postdoctoral Research Fellow, Active Pharmaceutical Ingredient-Formulation Interface, Solid State Pharmaceutical Cluster, University of Limerick. School of Pharmacy and Pharmaceutical Sciences, Trinity College, University of Dublin. 2005-2006: Research Assistant, Department of Pharmaceutical Technology and Biopharmaceutics, School of Pharmacy, Collegium Medicum, Jagiellonian University of Krakow. 2005-present: Community Pharmacist.

研究领域

Solid-state and micromeritic characterisation of spray dried microparticles Physicochemical characterisation of high-energy forms of active pharmaceutical ingredients Nanoparticulate-based delivery systems New salts and co-crystalline forms screening and characterisation

Solid-state and micromeritic characterisation of spray dried mmaterials; Physicochemical characterisation of high-energy forms of active pharmaceutical ingredients; Nanoparticulate delivery systems; Co-crystalline complexes screening and characterisation; Dissolution, Solubility, Permeability

近期论文

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Zaneta Wojnarowska, Krzysztof J Paluch, Evgeni Shoifet, Christoph Schick, Lidia Tajber, Justyna Knapik, Patryk Wlodarczyk, Katarzyna Grzybowska, Stella Hensel-Bielowka, Sergey P Verevkin, Marian Paluch, Molecular origin of enhanced proton conductivity in anhydrous ionic systems. Journal of the American Chemical Society. 2015, 137, 3, 1157-1164 DR Serrano, P O'Connell, KJ Paluch, D Walsh, AM Healy. Cocrystal habit engineering to improve drug dissolution and alter derived powder properties Journal of Pharmacy and Pharmacology 2015, DOI: 10.1111/jphp.12476 Matthias Manne Knopp, Lidia Tajber, Yiwei Tian, Niels Erik Olesen, David S Jones, Agnieszka Kozyra, Korbinian L?bmann, Krzysztof Paluch, Claire Marie Brennan, René Holm, Anne Marie Healy, Gavin P Andrews, Thomas Rades Comparative Study of Different Methods for the Prediction of Drug–Polymer Solubility, Molecular pharmaceutics. 2015, 12, 9, 3408-3419 Anita Umerska, Krzysztof Jan Paluch, Maria Jose Santos-Martinez, Carlos Medina, Owen I Corrigan, Lidia Tajber Chondroitin-based nanoplexes as peptide delivery systems–Investigations into the self-assembly process, solid-state and extended release characteristics European Journal of Pharmaceutics and Biopharmaceutics. 2015, 93, 242-253 M Dul, KJ Paluch, H Kelly, AM Healy, A Sasse, L Tajber, Self-assembled carrageenan/protamine polyelectrolyte nanoplexes—Investigation of critical parameters governing their formation and characteristics Carbohydrate polymers. 2015, 123, 339-349 Christine Grossjohann, Dolores R Serrano, Krzysztof J Paluch, Peter O'Connell, Liana Vella‐Zarb, Panagiotis Manesiotis, Thomas Mccabe, Lidia Tajber, Owen I Corrigan, Anne Marie Healy, Polymorphism in Sulfadimidine/4‐Aminosalicylic Acid Cocrystals: Solid‐State Characterization and Physicochemical Properties. Journal of Pharmaceutical Sciences. 2015, 104, 4, 1385-1398 T Zhang, K Paluch, G Scalabrino, N Frankish, AM Healy, H Sheridan. Molecular structure studies of (1S, 2S)-2-benzyl-2, 3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol. Journal of Molecular Structure. 2015, 1083, 286-299 Z. Wojnarowska, Y. Wang, K.J. Paluch, A.P. Sokolov, M. Paluch. Observation of highly decoupled conductivity in protic ionic conductors. Phys. Chem. Chem. Phys. 2014, 16(19), 9123-9127 Paluch K.J., McCabe T., Müller-Bunz H., Corrigan O.I., Healy A.M., Tajber L. Formation and physicochemical properties of crystalline and amorphous salts with different stoichiometries formed between ciprofloxacin and succinic acid. Mol. Pharm. 2013, 10(10), 3640-54 Wojnarowska Z., Grzybowska K., Hawelek L., Dulski M., Wrzalik R., Gruszka I., Paluch M., Pienkowska K., Sawicki W., Bujak P., Paluch K.J., Tajber L., Markowski J. Molecular dynamics, physical stability and solubility advantage from amorphous indapamide drug. Mol. Pharm. 2013, 10(10), 3612-27 Paluch, K.J., Tajber, L., Corrigan, O.I., and Healy, A.M., A novel approach to crystallisation of nanodispersible microparticles by spray drying for improved tabletability, Int. J. Pharm. 2012, 436(1-2), 873-6 Paluch, K.J., Tajber, L., Elcoate, C.J., Corrigan, O.I., Lawrence, S.E., Healy A.M., Solid state characterisation of novel active pharmaceutical ingredients: co-crystal of a salbutamol hemiadipate salt with adipic acid (2:1:1) and salbutamol hemisuccinate salt, J. Pharm. Sci. 2011, 100(8), 3268-3283 Paluch, K.J., Tajber, L., McCabe, T., O’Brien, J.E., Corrigan, O.I., Healy, A.M., Preparation and solid state characterisation of chlorothiazide sodium intermolecular self assembly suprastructure, Eur. J. Pharm. Sci. 2010, 41(5), 603 – 611