个人简介

1995-1998 PhD in Cytology, Morphology and Embryology, Humboldt University Berlin, Germany and People’s Friendship University Moscow, Russia 1985 -1990 DMD, Chuvash State University School of Medicine, Cheboksary, Russia

研究领域

Biology of the hair follicle:- molecular mechanisms controlling hair growth and their alterations in different hair loss conditions biological responses of the skin and hair follicle to environmental and other stressors mechanisms of skin and hair follicle aging molecular mechanisms controlling cutaneous wound repair

Skin and Hair Biology : miRNA : BMPs : Wound repair; Light

近期论文

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Mignon C, Botchkareva NV, Uzunbajakava NE, Tobin DJ. Photobiomodulation for hair regrowth and wound healing: a therapy full of promise but a literature full of confusion. Dermatol. 2016 Apr 20. doi: 10.1111/exd.13035. [Epub ahead of print] PubMed PMID: 27095546. http://www.ncbi.nlm.nih.gov/pubmed/27095546 Andl T, Botchkareva NV MicroRNAsmiRNAs) in the control of HF development and cycling: the next frontiers in hair research. . Exp Dermatol. 2015 Nov;24(11):821-6. doi: 10.1111/exd.12785. Epub 2015 Aug 25. Review. PubMed PMID: 26121602. http://www.ncbi.nlm.nih.gov/pubmed/26121602 MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway. Ahmed MI, Alam M, Emelianov VU, Poterlowicz K, Patel A, Sharov AA, Mardaryev AN, Botchkareva NV. J Cell Biol. 2014 Nov 24;207(4):549-67. doi: 10.1083/jcb.201404001. http://www.ncbi.nlm.nih.gov/pubmed/25422376 Sharova TY, Poterlowicz K, Botchkareva NV, Kondratiev NA, Aziz A, Spiegel JH, Botchkarev VA, Sharov AA. Complex Changes in the Apoptotic and Cell Differentiation Programs during Initiation of the Hair Follicle Response to Chemotherapy. J Invest Dermatol. 2014 Dec;134(12):2873-82. doi: 10.1038/jid.2014.267. http://www.ncbi.nlm.nih.gov/pubmed/24999588 Lewis CJ, Mardaryev AN, Poterlowicz K, Sharova TY, Aziz A, Sharpe DT, Botchkareva NV, Sharov AA. morphogenetic protein signaling suppresses wound-induced skin repair by inhibiting keratinocyte proliferation and migration. J Invest Dermatol. 2014 Mar;134(3):827-37. doi: 10.1038/jid.2013.419. http://www.ncbi.nlm.nih.gov/pubmed/24126843 First International Symposium "Epigenetic Control of Skin Development and Regeneration": how chromatin regulators orchestrate skin functions. Botchkarev VA, Fessing MY, Botchkareva NV, Westgate G, Tobin DJ. J Invest Dermatol. 2013 Aug;133(8):1918-21. doi: 10.1038/jid.2013.126 http://www.ncbi.nlm.nih.gov/pubmed/23856928 Botchkareva NV. MicroRNA/mRNA regulatory networks in the control of skin development and regeneration. (review) Cell Cycle. 2012;11(3):468-74. Ahmed MI, Mardaryev AN, Lewis CJ, Sharov AA, Botchkareva NV. MicroRNA-21 is an important downstream component of BMP signalling in epidermal keratinocytes. J Cell Sci. 2011;124 (Pt 20):3399-404 (featured article) http://www.ncbi.nlm.nih.gov/pubmed/21984808 Mardaryev AN, Ahmed MI, Vlahov NV, Fessing MY, Gill JH, Sharov AA, Botchkareva NV. MicroRNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle. FASEB Journal, 2010; 24:3869-81. http://www.ncbi.nlm.nih.gov/pubmed/20522784 Atoyan R, Shander D, Botchkareva NV. Non-Neuronal expression of transient receptor potential type A1 (TRPA1) in human skin.J Invest Dermatol.2009;129:2312-5. (featured article) Botchkareva NV, Kahn M, Ahluwalia G, Shander D. Survivin in the human hair follicle. J Invest Dermatol. 2007; 127:479-82. Botchkareva NV, Ahluwalia G., Shander D. Apoptosis in the hair follicle [review article]. J Invest Dermatol.2006; 126, 258-64. (invited review article)