个人简介

1986 - BSc Pharmacology with Basic Medical Science - Charing Cross and Westminster Medical School, London 1989 - MBBS - University of London 1997 - D.Phil. "Early inflammatory responses in mouse scrapie" - Dept. Pharmacology, University of Oxford (Supervisor: Professor V. H. Perry)

研究领域

Pathogenesis of neurodegenerative disease Digital pathology applications and implementations

Prion disease; pathogenesis of neurodegenerative disease; digital pathology

近期论文

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Betmouni S., Perry V.H. and Gordon J.L. (1996) Evidence for an early inflammatory response in the central nervous system of mice with scrapie. Neuroscience74(1): 1-5 Betmouni S. and Perry V.H. (1999) Acute inflammatory response in the CNS following injection of prion brain homogenate or normal brain homogenate. Neuropathology Applied Neurobiology25: 20-28 Betmouni S., Deacon R.M.J., Rawlins J.N.P. and Perry V.H. (1999) Behavioural consequences of prion disease targeted to the hippocampus in a mouse model of scrapie. Psychobiology. 27(1): 63-71 Bolton S. J., Russelakis-Carnerio M., Betmouni S. and Perry V.H. (1999) Non-nuclear histone is upregulated in neurons and astrocytes in prion and Alzheimer’s disease but not in acute neurodegeneration. Neuropathology Applied Neurobiology 25: 425-432 Russelakis-Carneiro M., Betmouni S. and Perry V.H. (1999) Inflammatory response and retinal ganglion cell degeneration following intraocular injection of ME7. Neuropathology Applied Neurobiology. 25:196-206 Betmouni S., Clements J. and Perry V.H. (1999) Vacuolation in murine scrapie: an informative artefact. Current Biology 9(18): R677-R679 Cross S. S., Betmouni S., Burton J.L., Dube A. K., Feeley K. M., Holbrook M.R., Landers R.J., Lumb P.B. and Stephenson T.J. (2000) What levels of agreement can be made between histopathologists assigning cases to discrete nominal categories? - a study of the diagnosis of hyperplastic and adenomatous polyps. Modern Pathology13: 941-944 Walsh D. T., Betmouni S. and Perry V. H. (2001) Absence of detectable IL-1 production in murine prion disease, a model of chronic neurodegeneration Journal Neuropathology and Experimental Neurology 60(2): 173-182 Fady J., Dawson K., Betmouni S., Moss T., and Smith P. (2005) The Bath Advanced Neurology Course 2003: Progressive neurological decline in pregnancy. Practical Neurology 5(3): 168-175 Chiti Z., Knutsen O.M., Betmouni S. and Greene J.R.T. (2006) Deficits in synaptic plasticity precede behavioural changes in murine prion disease. Neurobiology of Disease22: 363-373 Gray E., Thomas T.L., Betmouni S., Scolding N. and Love S. (2008) Elevated activity and microglial expression of myeloperoxidase in demyelinated cerebral cortex in multiple sclerosis. Brain Pathology18(1):86-95 Franklin S. L., Love S., Greene J.R.T. and Betmouni S. (2008) Loss of perineuronal net in ME7 prion disease. Journal of Neuropathology and Experimental Neurology67(3):189-199 Gray E., Thomas T.L., Betmouni S., Scolding N. and Love, S. (2008) Elevated MMP-9 and degradation of perineuronal net in cerebrocortical multiple sclerosis plaques. Journal of Neuropathology and Experimental Neurology67(9):888-899 Gray E., Thomas T.L., Betmouni S., Scolding N. and Love S. (2008) Elevated myeloperoxidase activity in white matter in multiple sclerosis. Neuroscience Letters444:195-198