Hartley, Paul - Bournemouth University - Department of Life & Environmental Science

个人简介

2005: PhD from the University of Edinburgh School of Clinical and Surgical Science (Supervisors Dr. Simon Brown & Prof. John Savill) 1995: BSc (Hons) University of Abertay Dundee, Biotechnology (1st class) 2000: Medical Research Council Human Reproductive Unit (Prof. Richard Anderson’s group) 2005: Medical Research Council Human Genetics Unit (Prof. Julia Dorin’s group) 2007: University of Edinburgh Circadian Physiology Group (Prof. Tony Harmar’s group) 2009: Principal Investigator, University of Edinburgh Centre for Cardiovascular Sciences 2013: British Heart Foundation Intermediate Basic Science Fellow 2013: Visiting Scientist Sanford Burnham Medical Research Inst, California (Prof. Rolf Bodmer’s group) 2015: Senior Lecturer (Functional Genetics) Bournemouth University

近期论文

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Hartley, P., 2016. SPARC-Dependent Cardiomyopathy in Drosophila. Circulation: Cardiovascular Genetics. Ivy, J.R., Drechsler, M., Catterson, J.H., Bodmer, R., Ocorr, K., Paululat, A. and Hartley, P.S., 2015. Klf15 is critical for the development and differentiation of drosophila nephrocytes. PLoS ONE, 10 (8). Hartley, P.S., 2013. Mice housed in groups of 4-6 exhibit a diurnal surge in their platelet count. Platelets, 24 (5), 412-414. Catterson, J.H., Heck, M.M.S. and Hartley, P.S., 2013. Fermitins, the Orthologs of Mammalian Kindlins, Regulate the Development of a Functional Cardiac Syncytium in Drosophila melanogaster. PLoS ONE, 8 (5). Tracey, C.J., Pan, X., Catterson, J.H., Harmar, A.J., Hussain, M.M. and Hartley, P.S., 2012. Diurnal expression of the thrombopoietin gene is regulated by CLOCK. Journal of Thrombosis and Haemostasis, 10 (4), 662-669. Hartley, P.S., 2012. The diurnal tick-tockery of platelet biology. Platelets, 23 (2), 157-160. Catterson, J.H., Knowles-Barley, S., James, K., Heck, M.M.S., Harmar, A.J. and Hartley, P.S., 2010. Dietary modulation of Drosophila sleep-wake behaviour. PLoS ONE, 5 (8). Hartley, P.S., Sheward, J., Scholefield, E., French, K., Horn, J.M., Holmes, M.C. and Harmar, A.J., 2009. Timed feeding of mice modulates light-entrained circadian rhythms of reticulated platelet abundance and plasma thrombopoietin and affects gene expression in megakaryocytes. British Journal of Haematology, 146 (2), 185-192. Hartley, P.S., John Sheward, W., French, K., Horn, J.M., Holmes, M.C. and Harmar, A.J., 2008. Food-entrained rhythmic expression of PER2 and BMAL1 in murine megakaryocytes does not correlate with circadian rhythms in megakaryopoiesis. Journal of Thrombosis and Haemostasis, 6 (7), 1144-1152. Hartley, P.S., 2007. Platelet senescence and death. Clinical Laboratory, 53 (3-4), 157-166. Hartley, P.S., Savill, J.S. and Brown, S.B., 2007. Hypoglycaemia predisposes platelets to death by affecting calcium homeostasis and mitochondrial integrity. Platelets, 18 (2), 103-112. Hartley, P.S., Savill, J. and Brown, S.B., 2006. The death of human platelets during incubation in citrated plasma involves shedding of CD42b and aggregation of dead platelets. THROMBOSIS AND HAEMOSTASIS, 95 (1), 100-106. Da Silva, S.J.M., Bayne, R.A.L., Cambray, N., Hartley, P.S., McNeilly, A.S. and Anderson, R.A., 2004. Expression of activin subunits and receptors in the developing human ovary: Activin A promotes germ cell survival and proliferation before primordial follicle formation. Developmental Biology, 266 (2), 334-345. Anderson, R.A., Cambray, N., Hartley, P.S. and McNeilly, A.S., 2002. Expression and localization of inhibin α, inhibin/activin βA and βB and the activin type II and inhibin β-glycan receptors in the developing human testis. Reproduction, 123 (6), 779-788. Hartley, P.S., Bayne, R.A.L., Robinson, L.L.L., Fulton, N. and Anderson, R.A., 2002. Developmental changes in expression of myeloid cell leukemia-1 in human germ cells during oogenesis and early folliculogenesis. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 87 (7), 3417-3427. Hartley, P.S., Dawson, B., Lindsay, C., McCormick, P. and Wishart, G., 1999. Cryopreservation of houbara semen: A pilot study. Zoo Biology, 18, 147-152.