个人简介
教育背景
2008-09--中国科学院上海药物研究所 理学博士
2003-09--中国药科大学 理学学士
工作简历
2015-10~现在, 中国科学院上海药物研究所, 副研究员
2013-07~现在, 中国科学院上海药物研究所, 助理研究员
2008-09~现在, 中国科学院上海药物研究所, 理学博士
2003-09~现在, 中国药科大学, 理学学士
社会兼职
2020-08-25-今,上海市药学会药理学专业委员会青年委员,
2019-12-30-今,中国药理学会抗炎免疫药理专业委员会青年委员,
近期论文
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Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp3)-H olefination mediated by donor/donor carbenes, Nat Commun, 2021, 第 1 作者
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis, Acta Pharmacologica Sinica., 2021, 通讯作者
Artemisinin analogue SM934 protects against lupus-associated antiphospholipid syndrome via activation of Nrf2 and its targets., Science China Life Sciences, 2021, 通讯作者
DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters., Int Immunopharmacol, 2021, 通讯作者
Anti-nociceptive, anti-inflammatory and anti-arthritic activities of pregnane glycosides from the root bark of Periploca sepium Bunge, J Ethnopharmacol, 2021, 通讯作者
Rh-Catalyzed C-H alkylation enabling modular synthesis of CF3-substituted benzannulated macrocyclic inhibitors of B cell responses, Org Biomol Chem, 2021, 第 1 作者
NOD-like receptors in autoimmune diseases, Acta Pharmacologica Sinica, 2021, 通讯作者
Minor immunosuppressive spiroorthoester group-containing pregnane glycosides from the root barks of Periploca sepium, Bioorganic Chemistry, 2021, 通讯作者
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-κB/NLRP3 signaling, Acta Pharmacologica Sinica, 2020, 通讯作者
Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides, Bioorg Chem, 2020, 通讯作者
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage, Arthritis Res Ther, 2019, 第 1 作者
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