Aggarwal, Varinder - University of Bristol

研究领域

My research interests include; the development of new catalytic processes for asymmetric synthesis; the development of chiral carbenoids and their use and subsequent applications in catalysis and synthesis; the development of new methodology and its applications in synthesis; total synthesis of biologically important targets. catalytic processes asymmetric synthesis reactive intermediates synthesis carbenes carbenoids

近期论文

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Shu, C, Noble, A & Aggarwal, VK, 2019, ‘Photoredox-Catalyzed Cyclobutane Synthesis via a Deboronative Radical Addition-Polar Cyclization Cascade’. Angewandte Chemie - International Edition, vol 58., pp. 3870-3874 Silvi, M & Aggarwal, VK, 2019, ‘Radical Addition to Strained σ-Bonds Enables the Stereocontrolled Synthesis of Cyclobutyl Boronic Esters’. Journal of the American Chemical Society, vol 141., pp. 9511-9515 Fawcett, A, Murtaza, A, Gregson, CHU & Aggarwal, VK, 2019, ‘Strain-Release-Driven Homologation of Boronic Esters: Application to the Modular Synthesis of Azetidines’. Journal of the American Chemical Society. Fawcett, A, Biberger, T & Aggarwal, VK, 2019, ‘Carbopalladation of C–C σ-bonds enabled by strained boronate complexes’. Nature Chemistry, vol 11., pp. 117-122 Wu, J, Grant, PS, Li, X, Noble, A & Aggarwal, VK, 2019, ‘Catalyst-Free Deaminative Functionalizations of Primary Amines via Photoinduced Single-Electron Transfer’. Angewandte Chemie - International Edition, vol 58., pp. 5697-5701 Nandakumar, M, Rubial, B, Noble, A, Myers, EL & Aggarwal, VK, 2019, ‘Ring-Opening Lithiation-Borylation of 2-Trifluoromethyl Oxirane: A Route to Versatile Tertiary Trifluoromethyl Boronic Esters’. Angewandte Chemie - International Edition. Fordham, JM, Grayson, MN & Aggarwal, VK, 2019, ‘Vinylidene Homologation of Boronic Esters and its Application to the Synthesis of the Proposed Structure of Machillene’. Angewandte Chemie - International Edition, vol 58., pp. 15268-15272 Kornilov, A, Kennedy, PD, Aldrovandi, M, Watson, A, Hinz, C, Harless, B, Colombo, J, Maxey, KM, Tyrrell, VJ, Simon, M, Aggarwal, VK, Boeglin, WE, Brash, AR, Murphy, RC & O'donnell, VB, 2019, ‘Revising the structure of a new eicosanoid from human platelets to 8,9-11,12-diepoxy-13-hydroxy-eicosadienoic acid’. Journal of Biological Chemistry, vol 294., pp. 9225-9238 Tillin, C, Bigler, R, Calo-lapido, R, Collins, B, Noble, A & Aggarwal, V, 2019, ‘Complex Boron-Containing Molecules through a 1,2-Metalate Rearrangement/anti-S N 2′ Elimination/Cycloaddition Reaction Sequence’. SYNLETT, vol 30., pp. 449-453 Rubial, B, Collins, BS, Bigler, R, Aichhorn, S, Noble, A & Aggarwal, VK, 2019, ‘Enantiospecific Synthesis of ortho-Substituted 1,1-Diarylalkanes by a 1,2-Metalate Rearrangement/anti-SN2′ Elimination/Rearomatizing Allylic Suzuki–Miyaura Reaction Sequence’. Angewandte Chemie - International Edition, vol 58., pp. 1366-1370 Wu, J, Baer, R, Guo, L, Noble, A & Aggarwal, VK, 2019, ‘Photoinduced Deoxygenative Borylations of Aliphatic Alcohols’. Angewandte Chemie - International Edition. Kaiser, D, Noble, A, Fasano, V & Aggarwal, VK, 2019, ‘1,2-Boron Shifts of β-Boryl Radicals Generated from Bis-boronic Esters Using Photoredox Catalysis’. Journal of the American Chemical Society, vol 141., pp. 14104-14109