Busby, Steve - University of Birmingham

个人简介

Postdocs 1975-1979 Institut Pasteur, Paris & NIH, Bethesda 1979-1983 Staff Scientist at Institut Pasteur, Paris 1983 Lecturer at the University of Birmingham 1988 Senior Lecturer 1990-1995 Royal Society EPA Fund Research Fellow & Reader in Biochemistry 1995-present Professor of Biochemistry 2005 FRS 2006 Fellow of the American Academy of Microbiology

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Browning, D, Grainger, D, Beatty, C, Wolfe, A, Cole, J & Busby, S (2005) Integration of three signals at the Escherichia coli nrf promoter: a role for Fis protein in catabolite repression. Molecular Microbiology 57 496-510 Grainger, D, Hurd, D, Harrison, M, Holdstock, J & Busby, S (2005) Studies of the distribution of Escherichia coli cAMP receptor protein and RNA polymerase along the E. coli chromosome. Proc Natl Acad Sci USA 102 17693-17698 Kahramanoglou, C, Webster, C, El-Robh, M, Belyaeva, T & Busby, S (2006) Mutational analysis of the Escherichia coli melR gene suggests a two-state concerted model to explain transcriptional activation and repression in the melibiose operon. J. Bacteriol. 188 3199-3207 Grainger, D, Hurd, D, Goldberg, M & Busby, S (2006) Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome. Nucl. Acids Res. 34 4642-4652 Browning, D, Lee, D, Wolfe, A, Cole, J & Busby, S (2006) The Escherichia coli K-12 NarL and NarP proteins insulate the nrf promoter from the effects of integration host factor. J. Bacteriol. 188 7449-7456 Wade, J, Roa, D, Grainger, D, Hurd, D, Busby, S & Struhl, K (2006) Extensive functional overlap between sigma factors in Escherichia coli. Nat. Struct. Mol. Biol. 13 806-814 Grainger, D, Hurd, D, Goldberg, M & Busby, S (2007) Transcription factor distribution in E coli: studies with FNR protein. Nucl. Acids Res. 35 269-278 Grainger, D, Goldberg, M, Lee, D & Busby, S (2008) Selective repression by Fis and H-NS at the Escherichia coli dps promoter. Molecular Microbiology 68 1366-1377 Shimada, T, Ishihama, A, Busby, S & Grainger D (2008) The Escherichia coli RutR transcription factor binds at targets within genes as well as intergenic regions. Nucl Acids Res. 36 3950-3955 Butala, M, Busby, S & Lee, D (2009) DNA sampling: a method for probing protein binding at specific loci on bacterial chromosomes. Nucl Acids Res doi:10.1093/nar/gkp043 Xu, M, Busby, S & Browning, D (2009) Activation and repression at the Escherichia coli ynfEFGHI operon promoter. J Bacteriol 191 3172-3176 Squire, D, Xu, M, Cole, J, Busby, S & Browning, D (2009) Competition between NarL-dependent activation and Fis-dependent repression controls expression from the Escherichia coli yeaR and ogt promoters. Biochem J 420 249-257 Piper, S, Mitchell, J, Lee, D & Busby, S(2009) A global view of Escherichia coli Rsd protein and its interactions. Molecular BioSystems 5 1943-1947 Lee, D, Bingle, L, Heurlier, K, Pallen, M, Penn, C, Busby, S & Hobman, J (2009) Gene doctoring: a method for recombineering in laboratory and pathogenic Escherichia coli strains. BMC Microbiology 9 252 Hollands, K, Lee, D, Lloyd, G & Busby, S (2010) Activation of sigma 28-dependent transcription in Escherichia coli by the cyclic AMP receptor protein requires an unusual promoter organisation. Molecular Microbiology 75 1098-1111 Lloyd, G, Godfrey R & Busby S (2010) Targets for the MalI repressor at the divergent Escherichia coli K-12 malX-malI promoters. FEMS Letters 305 28-34 Sánchez-Romero, M-A, Busby, S, Dyer, N, Ott, S, Millard, A & Grainger, D (2010) Dynamic distribution of SeqA protein across the chromosome of Escherichia coli K-12. mBio 1 e00012-10.doi10.1128/mBio00012-10 Browning, D, Lee, D, Spiro, S & Busby, S (2010) Down-regulation of the Escherichia coli K-12 nrf promoter by binding of the NsrR nitric oxide sensing transcription repressor to an upstream site. J. Bacteriol 192 3824-3828 Chismon, D, Browning, D, Farrant, G & Busby, S (2010) Unusual organization, complexity and redundancy at the Escherichia coli hcp-hcr promoter. Biochem J 430 61-68 Islam, M, Bingle, L, Pallen, M & Busby, S (2011) Organization of the LEE1 operon regulatory region of enterohaemorrhagic Escherichia coli O157:H7 and activation by GrlA. Molecular Microbiology 79 468-483