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Batt, S.M., T. Jabeen, V. Bhowruth, L. Quill, P.A. Lund, L. Eggeling, L.J. Alderwick, K. Fütterer, and G.S. Besra (2012) Structural basis of inhibition of M. tuberculosis DprE1 by benzothiazinone inhibitors. Proceedings of the National Academy of Sciences USA 109: 11354-11359. Jervis, P., L.M. Graham, E.L. Foster, L.R. Cox, S.A. Porcelli, and G.S. Besra (2012) New CD1d agonists: synthesis and biological activity of 6’-triazole-substituted a-galactosyl ceramides. Bioorg. Med. Chem. Lett. 22: 4348-4352. Detre, C., M. Keszei, N. Garrido-Mesa, K. Kis-Toth, W. Castro, A.F. Agyemang, N. Veerapen, G.S. Besra, M.C. Carroll, G.C. Tsokos, N. Wang, E.A. Leadbetter, and C. Terhorst (2012) SAP expression in invariant NKT cells in requisite for cognate help and dispensable for non-cognate support to B cells. Blood. 120: 122-129. Speak, A.O., N. Platt, M. Salio, D.T. Vruchte, D.A. Smith, D. Shepherd, N. Veerapen, G.S. Besra, N.M. Yanjanin, L. Simmons, J. Imrie, J.E. Wraith, R. Lachmann, R. Hartung, H. Runz, E. Mengel, M. Beck, C.J. Hendriksz, F.D. Porter, V. Cerundolo, and F.M. Platt (2012) Invariant Natural Killer T cells are not affected by lysosomal storage in pateinets with Niemann-Pick disease type C. Eur. J. Immunol. 42: 1886-1892. Mishra, A.K., K. Krumbach, D. Rittman, S. Batt, O.Y. Lee, S. De, J. Frunzke, G.S. Besra, and L. Eggeling (2012) Deletion of manC in Corynebacterium glutamicum results in a phospho-myo-inositol mannoside and lipoglycan deficient mutant. Microbiology. 158: 1908-1917. Varela, C., D. Rittmann, A. Singh, K. Krumbach, K. Bhatt, L. Eggeling, G.S. Besra*, and A. Bhatt (2012) MmpL genes are associated with mycolic acid metabolism in mycobacteria and corynebacteria. Chem Biol. 19(4): 498-506. [*co-corresponding author]. Woude, van der A.D., D. Sarkar, A. Bhatt, M. Sparrius, S.A. Raadsen, L. Boon, J. Geurtsen, A.M. van der Sar, J. Luirink, E.N. Houben, G.S. Besra, and W. Bitter (2012) An unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum. J. Biol. Chem. 287: 20417-20429. Wu, L., V.V. Parek, C.L. Gabriel, D.P. Bracy, P.A. Marks-Shulman, R.A. Tamboli, S. Kim, Y.V. Mendez-Fernandez, G.S. Besra, J.P. Lomenick, B. Williams, D.H. Wasserman, and L. van Kaer (2012) Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. Proc. Natl. Acad. Sci. USA. 109 (19): E1143-1152. Usha, V., J.V. Hobrath, S.S. Gurcha, R.C. Reynolds, and G.S. Besra (2012) Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis. PLoS ONE 7(3): e33886. Jervis, P.J., M. Moulis, J.P. Jukes, H. Ghadbane, L.R. Cox, V. Cerundolo, and G.S. Besra (2012) Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric a-galactosyl ceramide analogues. Carbohydr. Res. (2012) 356: 152-162. Usha, V., A.J. Lloyd, A.L. Lovering, and G.S. Besra (2012) Structure and function of Mycobacterium tuberculosis meso-diaminopimelic acid (DAP) biosynthesis enzymes. FEMS Microbiol. Lett. 330(1): 10-16. Leon, L., R.V. Tatituri, R. Grenha, Y. Sun, D.C. Barral, A.J. Minnaard, V. Bhowruth, N. Veerapen, G.S. Besra, A. Kasmar, W. Peng, D.B. Moody, G.A. Grabowski, and M. B. Brenner (2012) Saposins utilize two strategies for lipid transfer and CD1 antigen presentation. Proc. Natl. Acad. Sci. USA 109(12): 4357-4364. Jankute, M., S. Grover, A.K. Rana, and G.S. Besra (2012) Arabinogalactan and lipoarabinomannan biosynthesis: structure, biogenesis and their potential as drug targets. Future Microbiol. 7(1): 129-147. Wojno, J., J.P. Jukes, H. Ghadbane, D. Shepherd, G.S. Besra*, V. Cerundolo, and L.R. Cox (2012) Amide analogs of CD1d agonists modulate iNKT cell-mediated cytokine production. ACS Chem. Biol. 7: 847-855 [*co-corresponding author] King, I.L., A. Fortier, M. Tighe, J. Dibble, G. F.M. Watts, N. Veerapen, A.M. Haberman, G.S. Besra, M. Mohrs, M.B. Brenner, and E.A. Leadbetter (2011) iNKT cells direct B cell responses to cognate lipid antigen in an interleukin 21-dependent manner. Nat. Immunol. 13(1): 44-50. Cohen, N.R., R.V.V. Tatituri, A. Rivera, G. Watts, A. Chiba, G.S. Besra, E.G. Pamer, M. Brigl, and M.B. Brenner (2011) Innate recognition of cell wall b-glucan via Dectin-1 drives iNKT cell responses against fungi. Cell Host & Microbe, 10(5): 437-450. Patel, O., D.G. Pellicci, A.P. Uldrich, L.C. Sullivan, M. Bhati, M. McKnight, S.K. Richardson, A.R. Howell, T. Mallevaey, J. Zhang, R. Bedel, G.S. Besra, A.G. Brooks, L.K. Nielsen, J. McClusky, S.A. Porcelli, L. Gapin, J. Rossjohn, and D.I. Godfrey (2011) Vb2 Natural killer T cell receptor mediated recognition of CD1d-glycolipid antigen. Proc. Natl. Acad. Sci. USA, 8(47): 19007-19012. Kinjo, Y., P. Illarionov, J.L. Vela, B. Pei, E. Girardi, X. Li, Y. Li, M. Imamura, Y. Kaneko, A. Okawara, Y. Miyazaki, A. Gomez-Velasco, P. Rogers, S. Dahesh, S. Uchiyama, A. Khurana, K. Kawahara, H. Yesilkaya, P.W. Andrew, C-H Wong, K. Kawakami, V. Nizet, G.S. Besra, M. Tsuji, D.M. Zajonc, and M. Kronenberg (2011) Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nat. Immunol. 12: 966-974. Muppidi, J.R., T.I. Arnon, Y. Bronevetsky, N. Veerapen, M. Tanaka, G.S. Besra, and J.G. Cyster (2011) Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. J. Exp. Med. 208: 1941-1948. Pellicci, D.G., A.J. Clarke, O. Patel, T. Mallevaey, T. Beddoe, J. Le Nours, A.P. Uldrich, J. McCluskey, G.S. Besra, S.A. Porcelli, L. Gapin, D.I. Godfrey, and J. Rossjohn (2011) Recognition of b-linked self glycolipids mediated by natural killer T cell antigen receptors. Nat. Immunol. 12: 827-833.