Hannon, Michael John - University of Birmingham

个人简介

Mike Hannon qualified with a first class B.A. (Hons) in Natural Sciences from the University of Cambridge in 1990. He remained at Cambridge (90-93) to study for a PhD in Inorganic Chemistry with Professor Ed Constable and then was awarded a Royal Society ESEP Fellowship to work with Nobel laureate Professor Jean-Marie Lehn in Strasbourg (93-94). He returned to the UK in 1994 to take up a lectureship at the University of Warwick. He received two awards for teaching excellence, and was promoted to Professorship in 2005. He was appointed to the Chair of Chemical Biology at the University of Birmingham in Autumn 2005 and became Director of the PSIBS Biomedical Imaging Centre in 2008.

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Noncovalent DNA-Binding Metallo-Supramolecular Cylinders Prevent DNA Transactions in vitro C. Ducani, A. Leczkowska, N.J. Hodges, M.J. Hannon, Angew. Chem. Intl. Ed., 2010, 49, 8942-8945, DOI: 10.1002/anie.201004471 Conjugation of testosterone modifies the interaction of mono-functional cationic platinum(II) complexes with DNA, causing significant alterations to the DNA helix C. Sanchez-Cano, M. Huxley, C. Ducani, A.E. Hamad, M.J. Browning, C. Navarro-Ranninger, A.G. Quiroga, A. Rodger, M. J. Hannon, Dalton Trans., 2010, 39, 11365-11374, DOI: 10.1039/C0DT00839G An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug M. Huxley, C. Sanchez-Cano, M.J. Browning, C. Navarro-Ranninger, A.G. Quiroga, A. Rodger, M. J. Hannon, Dalton Trans., 2010, 39, 11353-11364, DOI: 10.1039/C0DT00838A Towards functionalizable DNA frames: Self assembly of two-component 3D DNA arrays through induction of DNA three-way junction branch points by supramolecular cylinders D.R. Boer, J. M. C. A. Kerckhoffs, Y. Parajo, M. Pascu, I. Us?n, P. Lincoln, M.J. Hannon, M. Coll , Angew. Chem. Intl. Ed., 2010, 49, 2336-2339, DOI: 10.1002/anie.200906742 Issues surrounding standard cytotoxicity testing for assessing activity of non-covalent DNA-binding metallo-drugs A.J. Pope, C. Bruce, B. Kysela, M.J. Hannon, Dalton Trans., 2010, 39, 2772-2774, DOI: 10.1039/b927129p Electron Capture Dissociation Mass Spectrometry of Metallo-Supramolecular Complexes. M.A. Kaczorowska, A.C.G. Hotze, M.J. Hannon, H.J. Cooper, J. Am. Soc. Mass. Spectom., 2009, 21, 300-309, DOI:10.1016/j.jasms.2009.10.018 Novel and emerging approaches for the delivery of metallo-drugs. C. Sanchez-Cano and M.J. Hannon, Dalton Trans., 2009, 48, 10702-10711. DOI:10.1039/b912708 Cytotoxicity, cellular localisation and biomolecular interaction of non- covalent metallo-intercalators with appended sex hormone steroid vectors. C. Sanchez-Cano, M.J. Hannon, Dalton Trans., 2009, 48, 10765-10773. DOI:10.1039/b912711a Preparation of novel banana-shaped triple helical liquid crystals by metal coordination. P. Iqbal, M. Mayanditheuar, L. Childs, M.J. Hannon, N. Spencer, P.R. Ashton, J.A. Preece, Materials, 2009, 2, 146-168. DOI:10.3390/ma2010146 Effect of bridging ligand structure on the thermal stability and DNA binding properties of iron(ii) triple helicates. Y. Parajo, J. Malina, I. Meistermann, G.J. Clarkson, M. Pascu, A. Rodger, M.J. Hannon, Per Lincoln, Dalton Trans., 2009, 25, 4868-4874.DOI: 10.1039/b822039e Ruthenium polypyridyl complexes and their modes of interaction with DNA: Is there a correlation between these interactions and the antitumor activity of the compounds? E. Corral, A.C. Hotze, H. den Dulk, A. Leczkowska, A. Rodger, M.J. Hannon. J. Reedijk, J. Biol. Inorg. Chem., 2009, 14, 439-448.DOI 10.1007/s00775-008-0460-x Antimicrobial activity of an iron triple helicate. A.D. Richards, A. Rodger, M.J. Hannon, A. Bolhuis, Int. J. Antimicrob. Agents, 2009, 33, 469-472. DOI10.1016/j.ijantimicag.2008.10.031 Design and DNA-binding of metallo-supramolecular cylinders conjugated to peptides L. Cardo, M.J. Hannon, Inorg. Chim. Acta., 2009, 362, 784-792. DOI 10.1016/j.ica.2008.02.050 A supramolecular triple-stranded iron cylinder with unprecedented DNA binding action is a potent cytostatic and apoptotic agent without exhibiting genotoxicity A.C.G. Hotze, N.J. Hodges, R.E. Hayden, C. Sanchez-Cano, C. Paines, N. Male, M.-K. Tse, C.M. Bunce, J.K. Chipman, M.J. Hannon, Chemistry & Biology, 2008, 15, 1258-1267. DOI 10.1016/j.chembiol.2008.10.016 DNA binding and bending by dinuclear complexes comprising ruthenium polypyridyl centres linked by a bis(pyridylimine) ligand U. McDonnell, M. R. Hicks, M. J. Hannon, A. Rodger, J Inorg Biochem., 2008, 102, 2052-2059. DOI 10.1016/j.jinorgbio.2008.06.006 Interactions of Dinuclear Ruthenium(II) Supramolecular Cylinders with DNA. Sequence-specific Binding, Unwinding and Photocleavage J. Malina, M. J. Hannon, and V. Brabec, Chem. Eur J., 2008, 14, 10408-10414. DOI 10.1002/chem.200801364 DNA binding of dinuclear iron(II) metallosupramolecular cylinders. DNA unwinding and sequence preference J. Malina, M. J. Hannon, V. Brabec, Nucleic Acids Res., 2008, 36, 3630-3638. DOI 10.1093/nar/gkn244 Effect of adenine moiety on DNA binding property of copper(II)-terpyridine complexesQ. Jiang, Z.Y. Wu, Y.M. Zhang, A.C.G. Hotze, M.J. Hannon, Z.J. Guo, Dalton Trans., 2008, 3054-60. DOI: 10.1039/b719010g New organogelators based on cyclotriveratrylene platforms bearing 2-dimethylacetal-5-carbonylpyridine fragments D. Bardelang, F. Camerel, R. Ziessel , M. Schmutz, M. J. Hannon, J. Mater. Chem, 2008, 18, 489-494. DOI 10.1039/b712413a Synthesis and Cytotoxicity of Dinuclear Complexes containing Ruthenium(II) Bipyridyl units linked by a bis-pyridylimine ligandU. McDonnell, J.M.C.A. Kerchoffs, R.P.M. Castineiras, M.R. Hicks, A.C.G. Hotze, M.J. Hannon, A. Rodger, Dalton Trans., 2008, 667-675. DOI 10.1039/b711080d