近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Tait, M. B., Butterworth, S., Clayden, J., ‘2,2- and 2,6-diarylpiperidines by aryl migration within lithiated urea derivatives of tetrahydropyridines’. Organic Letters 2015, 17, 1236-1239. Butterworth S., Overduin M., Barr A. J.: Targeting Protein Tyrosine Phosphatase SHP2 for therapeutic intervention. Future Medicinal Chemistry 2014, 6(12), 1423-1427. Finlay M. R. V., Anderton M., Ashton S., Ballard P., Bethel P. A., Box M., Bradbury R. H., Brown S. J., Butterworth S., Campbell A, Chorley C, Colclough N, Cross DA, Currie GS, Grist M, Hassall L, Hill GB, James D, James M, Kemmitt P, Klinowska T, Lamont G, Lamont SG, Martin N, McFarland HL, Mellor MJ, Orme JP, Perkins D, Perkins P, Richmond G, Smith P, Ward RA, Waring MJ, Whittaker D, Wells S, Wrigley GL.: Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor. Journal of Medicinal Chemistry 2014, 57(20), 8249-8267. Ward, R. A., Anderton, M. J., Ashton, S., Bethel, P. A., Matthew Box, Butterworth, S., et al.: Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR). Journal of Medicinal Chemistry 2013 56, 7025-7048. Butterworth, Sam; Finlay, Maurice Raymond Verschoyle; Ward, Richard Andrew; Kadambar, Vasantha Krishna; Chandrashekar, Reddy C.; Murugan, Andiappan; Redfearn, Heather Marie; Preparation of 2-(2,4,5-substituted-anilino)pyrimidine derivatives as EGFR modulators useful for treating cancer. WO 2013014448. Carr G., Butterworth S., Walker, P., Reck F., Geng B., Pandarinathan L.: A multi-kilo scale synthesis of (R)-methyl 2-((1r,4R)-4-(tert-butoxycarbonylamino)cyclohexyl)-2-(2-nitrophenylsulfonamido) acetate. Synthesis (2012), 44(6), 875-880. Donohoe, T. J., Wheelhouse, K. M. P., Lindsay-Scott, P. J., Churchill, G. H., Connolly, M. J., Butterworth, S., Glossop, P. A.: Osmium-Mediated Oxidative Cyclizations: A Study into the Range of Initiators That Facilitate Cyclization. Chemistry - An Asian Journal 2009, 4(8), 1237-1247. Kaiser, J., van Esseveldt, B. C. J., Segers, M. J. A., van Delft, F. L., Smits, J. M. M., Butterworth, S., Rutjes, F. P. J. T.: Synthesis and aromatization of cyclic enediyne-containing amino acids. Organic & Biomolecular Chemistry 2009, 7(4), 695-705. Donohoe, T. J., Harris, R. M., Butterworth, S., Burrows, J. N., Cowley, A., Parker, J. S.: New osmium-based reagent for the dihydroxylation of alkenes. Journal of Organic Chemistry 2006, 71(12), 4481-4489. Donohoe, T. J., Butterworth, S.: Oxidative cyclization of diols derived from 1,5-dienes: Formation of enantiopure cis-tetrahydrofurans by using catalytic osmium tetroxide; formal synthesis of (+)-cis-solamin. Angewandte Chemie, International Edition 2005, 44(30), 4766-4768. Donohoe, T. J., Butterworth, S.: A general oxidative cyclization of 1,5-dienes using catalytic osmium tetroxide. Angewandte Chemie, International Edition 2003, 42(8), 948-951