孟露明 - 华南师范大学 - 生物光子学研究院

个人简介

2017/09 至今华南师范大学生物光子学研究院副研究员 2015/07 — 2017/08北京大学化学与分子工程学院博士后 2015/01 — 2015/06香港科技大学化学系访问学者 2010/08 — 2014/12香港科技大学纳米科学与技术专业博士 2006/09 — 2010/06中国科学技术大学化学物理系本科

研究领域

1. 通过理论建模方法重构出满足Hi-C实验数据的染色质三维结构。 2. 研究染色质三维结构与其生物学功能之间的联系

近期论文

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Meng, L. M.; Sheong, F. K.; Zeng, X. Z.; Zhu, L. Z.; Huang, X. H., Path lumping: An efficient algorithm to identify metastable path channels for conformational dynamics of multi-body systems. J Chem Phys 2017, 147 (4). Xie W.; Meng L. M. (co-first author); Liu S.; Zhang L.; Cai X.; Gao Y.*, Structural Modeling of Chromatin Integrates Genome Features and Reveals Chromosome Folding Principle, Sci. Rep. (2017) DOI:10.1038/s41598-017-02923-6 Hong, Y. N.; Meng, L. M.; Chen, S. J.; Leung, C. W. T.; Da, L. T.; Faisal, M.; Silva, D. A.; Liu, J. Z.; Lam, J. W. Y.; Huang, X. H.*; Tang, B. Z.*, Monitoring and Inhibition of Insulin Fibrillation by a Small Organic Fluorogen with Aggregation-Induced Emission Characteristics., J. Am. Chem. Soc. 134 (3), 1680-1689, (2012). Bowman, G. R.*; Meng, L. M.; Huang, X. H., Quantitative comparison of alternative methods for coarse-graining biological networks. J. Chem. Phys. 139 , 121905, (2013). Gu, S.; Silva, D. A.; Meng, L. M.; Yue, A.; Huang, X. H.*, Quantitatively Characterizing the Ligand Binding Mechanisms of Choline Binding Protein Using Markov State Model Analysis. PLoS Comput. Biol. 10 (8), e1003767, (2014). Sheong, F. K.; Silva, D. A.; Meng, L. M.; Zhao, Y. T.; Huang, X. H.*, Automatic State Partitioning for Multibody Systems (APM): An Efficient Algorithm for Constructing Markov State Models To Elucidate Conformational Dynamics of Multibody Systems. J. Chem. Theory Comput. 11 (1), 17-27, (2015). Zheng, X. Y.; Zhu, L. Z.; Zeng, X. Z.; Meng, L. M.; Zhang, L.; Wang, D.; Huang, X. H.*, Kinetics-Controlled Amphiphile Self-Assembly Processes. J. Phys. Chem. Lett. 8 (8), 1798-1803, (2017). Liu, J. Z.; Su, H. M.; Meng, L. M.; Zhao, Y. H.; Deng, C. M.; Ng, J. C. Y.; Lu, P.; Faisal, M.; Lam, J. W. Y.; Huang, X. H.; Wu, H. K.; Wong, K. S.*; Tang, B. Z.*, What makes efficient circularly polarised luminescence in the condensed phase: aggregation-induced circular dichroism and light emission. Chem. Sci. 3 (9), 2737-2747, (2012). Wang, E. J.; He, Z. K.; Zhao, E. G.; Meng, L. M.; Schutt, C.; Lam, J. W. Y.; Sung, H. H. Y.; Williams, I. D.; Huang, X. H.; Herges, R.*; Tang, B. Z.*, Aggregation-Induced-Emission-Active Macrocycle Exhibiting Analogous Triply and Singly Twisted Mobius Topologies. Chem. Eur. J. 21 (33), 11707-11711, (2015). Zhao, E.; Lam, J. W. Y.; Meng, L. M.; Hong, Y.; Deng, H. Q.; Bai, G. X.; Huang, X. H.; Hao, J. H.; Tang, B. Z.*, Poly[(maleic anhydride)-alt-(vinyl acetate)]: A Pure Oxygenic Nonconjugated Macromolecule with Strong Light Emission and Solvatochromic Effect. Macromolecules 48 (1), 64-71, (2015). Xue S.; Meng L. M.; Wen R.; Shi L.; Lam, J. W. Y.; Tang Z.; Li B. S.*; Tang B. Z.*; Unexpected aggregation induced circular dichroisim, circular polarized luminecence and helical assembly from achiral hexaphenylsilole (HPS). RSC Adv. 7, 24841-24847, (2017).