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Ding, H., Czoty, P. W., Kiguchi, N., Cami-Kobeci, G., Sukhtankar, D. D., Nader, M. A., Husbands, S. M. and Ko, M.-C., 2016. A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates. Proceedings of the National Academy of Sciences of the United States of America Grabski, M., Curran, H. V., Nutt, D. J., Husbands, S. M., Freeman, T. P., Fluharty, M. and Munafò, M. R., 2016. Behavioural tasks sensitive to acute abstinence and predictive of smoking cessation success:a systematic review and meta-analysis. Addiction Blazer, L. L., Storaska, A. J., Jutkiewicz, E. M., Turner, E. M., Calcagno, M., Wade, S. M., Wang, Q., Huang, X.-P., Traynor, J. R., Husbands, S. M., Morari, M. and Neubig, R. R., 2015. Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors. ACS Chemical Neuroscience, 6 (6), pp. 911-919. Huang, W., Manglik, A., Venkatakrishnan, A. J., Laeremans, T., Feinberg, E. N., Sanborn, A. L., Kato, H. E., Livingston, K. E., Thorsen, T. S., Kling, R. C., Granier, S., Gmeiner, P., Husbands, S. M., Traynor, J. R., Weis, W. I., Steyaert, J., Dror, R. O. and Kobilka, B. K., 2015. Structural insights into μ-opioid receptor activation. Nature, 524 (7565), pp. 315-321. Husbands, S., 2015. Meet our editorial board member. Mini-Reviews in Medicinal Chemistry, 15 (10), p. 797. Lowe, J. D., Sanderson, H. S., Cooke, A. E., Ostovar, M., Tsisanova, E., Withey, S. L., Chavkin, C., Husbands, S. M., Kelly, E., Henderson, G. and Bailey, C. P., 2015. Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization. Molecular Pharmacology, 88 (2), pp. 347-356. Almatroudi, A., Husbands, S. M., Bailey, C. P. and Bailey, S. J., 2015. Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in mice. Journal of Psychopharmacology, 29 (7), pp. 812-821. Cueva, J. P., Roche, C., Ostovar, M., Kumar, V., Clark, M. J., Hillhouse, T. M., Lewis, J. W., Traynor, J. R. and Husbands, S. M., 2015. C7β-methyl analogues of the orvinols:the discovery of kappa opioid antagonists with nociceptin/orphanin FQ peptide (NOP) receptor partial agonism and low, or zero, efficacy at Mu opioid receptors. Journal of Medicinal Chemistry, 58 (10), pp. 4242-4249. Alotaibi, M. R., Husbands, S. M. and Blagbrough, I. S., 2015. 1H, 13C, 15N HMBC, and 19F NMR spectroscopic characterisation of seized flephedrone, cut with benzocaine. Journal of Pharmaceutical and Biomedical Analysis, 107, pp. 535-538. Khroyan, T. V., Wu, J., Polgar, W. E., Cami-Kobeci, G., Fotaki, N., Husbands, S. M. and Toll, L., 2015. BU08073 a buprenorphine analog with partial agonist activity at μ-receptors in vitro but long-lasting opioid antagonist activity in vivo in mice. British Journal of Pharmacology, 172 (2), pp. 668-680. Bailey, S., Almatroudi, A. M. I., Bailey, C. and Husbands, S., 2015. The antidepressant-like effects of BU10119, a novel kappa opioid receptor antagonist, in the novelty-induced hypophagia task in mice. In: Society for Neuroscience 2015, 2015-10-17 - 2015-10-21, Chicago. Bailey, C. P. and Husbands, S. M., 2014. Novel approaches for the treatment of psychostimulant and opioid abuse-focus on opioid receptor-based therapies. Expert Opinion on Drug Discovery, 9 (11), pp. 1333-1344. Kumar, V., Clark, M.J., Traynor, J.R., Lewis, J.W. and Husbands, S.M., 2014. Pyrrolo- and pyridomorphinans:Non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists. Bioorganic and Medicinal Chemistry, 22 (15), pp. 4067-4072. Almatroudi, A., Husbands, S. M., Bailey, C. P. and Bailey, S. J., 2014. Combination Treatment With Buprenorphine/Naltrexone, A Functional Kappa Opioid Receptor Antagonist, Produces Antidepressant-Like Effects In Mice. Journal of Psychopharmacology, 28 (8), A101. Cordery, S. F., Taverner, A., Ridzwan, I. E., Guy, R. H., Delgado-Charro, M. B., Husbands, S. M. and Bailey, C. P., 2014. A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm. Addiction Biology, 19 (4), pp. 575-586. Kumar, V., Ridzwan, I.E., Grivas, K., Lewis, J.W., Clark, M.J., Meurice, C., Jimenez-Gomez, C., Pogozheva, I., Mosberg, H., Traynor, J.R. and Husbands, S.M., 2014. Selectively promiscuous opioid ligands:Discovery of high affinity/low efficacy opioid ligands with substantial nociceptin opioid peptide receptor affinity. Journal of Medicinal Chemistry, 57 (10), pp. 4049-4057. Parker, C.A., Nabulsi, N., Holden, D., Lin, S.-F., Cass, T., Labaree, D., Kealey, S., Gee, A.D., Husbands, S.M., Quelch, D., Carson, R.E., Nutt, D.J., Huang, Y. and Tyacke, R.J., 2014. Evaluation of 11C-BU99008, a PET Ligand for the Imidazoline Binding Sites in Rhesus Brain. The Journal of Nuclear Medicine, 55 (5), pp. 838-844. Kealey, S., Husbands, S. M., Bennacef, I., Gee, A. D. and Passchier, J., 2014. Palladium-mediated oxidative carbonylation reactions for the synthesis of 11C-radiolabelled ureas. Journal of Labelled Compounds & Radiopharmaceuticals, 57 (4), pp. 202-208. Casal-Dominguez, J. J., Furkert, D., Ostovar, M., Teintang, L., Clarke, M. J., Traynor, J. R., Husbands, S. M. and Bailey, S. J., 2014. Characterization of BU09059:A novel potent selective κ-receptor antagonist. ACS Chemical Neuroscience, 5 (3), pp. 177-184. Ju, M., Scott-ward, T. S., Liu, J., Khuituan, P., Li, H., Cai, Z., Husbands, S. M. and Sheppard, D. N., 2014. Loop diuretics are open-channel blockers of the cystic fibrosis transmembrane conductance regulator with distinct kinetics. British Journal of Pharmacology, 171 (1), pp. 265-278.

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