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Williams, R. J., Mohanakumar, K. P. and Beart, P. M., 2016. Neuro-nutraceuticals: Further insights into their promise for brain health. Neurochemistry International, 95, pp. 1-3. Williams, R. J., Mohanakumar, K. and Beart, P. M., 2015. Neuro-nutraceuticals:the path to brain health via nourishment is not so distant. Neurochemistry International, 89, pp. 1-6. Cox, C. J., Choudhry, F., Peacey, E., Perkinton, M. S., Richardson, J. C., Howlett, D. R., Lichtenthaler, S. F., Francis, P. T. and Williams, R. J., 2015. Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing. Neurobiology of Aging, 36 (1), pp. 178-187. Tan, M. G. K., Lee, C., Lee, J. H., Francis, P. T., Williams, R. J., Ramírez, M. J., Chen, C. P., Wong, P. T.-H. and Lai, M. K. P., 2014. Decreased rabphilin 3A immunoreactivity in Alzheimer's disease is associated with Aβ burden. Neurochemistry International, 64, pp. 29-36. Hoey, S. E., Buonocore, F., Cox, C. J., Hammond, V. J., Perkinton, M. S. and Williams, R. J., 2013. AMPA receptor activation promotes non-amyloidogenic amyloid precursor protein processing and suppresses neuronal amyloid-β production. PLoS ONE, 8 (10), e78155. Pereira Morais, M. P., Marshall, D., Flower, S. E., Caunt, C. J., James, T. D., Williams, R. J., Waterfield, N. R. and Van Den Elsen, J. M. H., 2013. Analysis of protein glycation using fluorescent phenylboronate gel electrophoresis. Scientific Reports, 3, 1437. Vazour, D., Rattray, M., Williams, R. J. and Spencer, J., 2013. Potential neuroprotective actions of dietary flavonoids. In: Ramawat, K. G. and Merillion, J.-M., eds. Handbook of Natural Products. Springer, pp. 2617-2640. Guadagna, S., Esiri, M. M., Williams, R. J. and Francis, P. T., 2012. Tau phosphorylation in human brain: relationship to behavioral disturbance in dementia. Neurobiology of Aging, 33 (12), pp. 2798-2806. Bahia, P. K., Pugh, V., Hoyland, K., Hensley, V., Rattray, M. and Williams, R. J., 2012. Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activity. Journal of Neurochemistry, 123 (1), pp. 182-191. McHugh, P. C., Wright, J. A., Williams, R. J. and Brown, D. R., 2012. Prion protein expression alters APP cleavage without interaction with BACE-1. Neurochemistry International, 61 (5), pp. 672-680. Choudhry, F., Howlett, D. R., Richardson, J. C., Francis, P. T. and Williams, R. J., 2012. Pro-oxidant diet enhances β/γ secretase-mediated APP processing in APP/PS1 transgenic mice. Neurobiology of Aging, 33 (5), pp. 960-968. Spencer, J. P. E., Vafeiadou, K., Williams, R. J. and Vauzour, D., 2012. Neuroinflammation: Modulation by flavonoids and mechanisms of action. Molecular Aspects of Medicine, 33 (1), pp. 83-97. Williams, R. J. and Spencer, J. P. E., 2012. Flavonoids, cognition, and dementia: Actions, mechanisms, and potential therapeutic utility for Alzheimer disease. Free Radical Biology & Medicine, 52 (1), pp. 35-45. Gaeta, A., Molina-Holgado, F., Kong, X. L., Salvage, S., Fakih, S., Francis, P. T., Williams, R. J. and Hider, R. C., 2011. Synthesis, physical-chemical characterisation and biological evaluation of novel 2-amido-3-hydroxypyridin-4(1H)-ones: Iron chelators with the potential for treating Alzheimer's disease. Bioorganic & Medicinal Chemistry, 19 (3), pp. 1285-97. Thambisetty, M., Simmons, A., Velayudhan, L., Hye, A., Campbell, J., Zhang, Y., Wahlund, L.-O., Westman, E., Guntert, A., Kinsey, A., Proitsi, P., Powell, J., Causevic, M., Killick, R., Lunnon, K., Lynham, S., Broadstock, M., Choudhry, F., Howlett, D., Williams, R., Sharp, S., Mitchlemore, C., Tunnard, C., Leung, R., Foy, C., O'Brien, D., Breen, G., Furney, S., Ward, M., Kloszewska, I., Mecocco, P., Soininen, H., Tsolaki, M., Vellas, B., Hodges, A., Murphy, D., Parkins, S., Richardson, J., Resnik, S., Ferrucci, L., Wong, D., Zhou, Y., Muehlboeck, S., Evans, A., Francis, P., Spenger, C. and Lovestone, S., 2010. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Archives of General Psychiatry, 67 (7), pp. 739-748. Rainey-Smith, S. R., Andersson, D. A., Williams, R. J. and Rattray, M., 2010. Tumour necrosis factor alpha induces rapid reduction in AMPA receptor-mediated calcium entry in motor neurones by increasing cell surface expression of the GluR2 subunit: relevance to neurodegeneration. Journal of Neurochemistry, 113 (3), pp. 692-703. Hoey, S. E., Williams, R. J. and Perkinton, M. S., 2009. Synaptic NMDA receptor activation stimulates α-secretase amyloid precursor protein processing and inhibits amyloid-β production. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience, 29 (14), pp. 4442-4460. Vafeiadou, K., Vauzour, D., Lee, H. Y., Rodriguez-Mateos, A., Williams, R. J. and Spencer, J. P. E., 2009. The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury. Archives of Biochemistry and Biophysics, 484 (1), pp. 100-109. Vafeiadou, K., Vauzour, D., Rodriguez-Mateos, A., Whiteman, M., Williams, R. and Spencer, J., 2008. Glial metabolism of quercetin reduces its neurotoxic potential. Archives of Biochemistry and Biophysics, 478 (2), pp. 195-200. Bahia, P. K., Rattray, M. and Williams, R. J., 2008. Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes. Journal of Neurochemistry, 106 (5), pp. 2194-2204. Abbott, J. J., Howlett, D. R., Francis, P. T. and Williams, R. J., 2008. Aβ1-42 modulation of Akt phosphorylation via α7 nAChR and NMDA receptors. Neurobiology of Aging, 29 (7), pp. 992-1001. Rainey-Smith, S., Schroetke, L.-W., Bahia, P., Fahmi, A., Skilton, R., Spencer, J. P. E., Rice-Evans, C., Rattray, M. and Williams, R. J., 2008. Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation. Neuroscience Letters, 438 (1), pp. 29-33. Pezet, S., Marchand, F., D'Mello, R., Grist, J., Clark, A. K., Malcangio, M., Dickenson, A. H., Williams, R. J. and McMahon, S. B., 2008. Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience, 28 (16), pp. 4261-4270. Molina-Holgado, F., Gaeta, A., Francis, P. T., Williams, R. J. and Hider, R. C., 2008. Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells. Journal of Neurochemistry, 105 (6), pp. 2466-2476.