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个人简介

全国高校青年教师教学竞赛理科组二等奖(第六届,2023年) 平原学者(拔尖人才)(2022年入选) 中原英才计划(育才系列)——中原青年拔尖人才(2021年入选) 河南省优秀青年基金获得者(2020年入选) 河南省优秀教师(2023) 河南省优秀硕士学位论文指导教师(2020年入选) 河南省教育厅学术技术带头人(2019年入选) 河南省高校科技创新团队支持计划获得者(2022) 河南省高校科技创新人才(2019年入选) 河南省教学标兵(2021) 新乡市市长教育质量奖——名教师质量奖获得者(2021年入选) 新乡市首届五四青年奖章(2022) 河南师范大学第六届青年教师课堂教学十佳教师(2021年入选) 教育与研究经历 2004年9月-2008年6月 四川大学 化学学院 理学 学士 2008年9月-2013年6月 四川大学 化学学院 理学 博士 (硕博连读,导师:冯小明 院士) 2013年7月-至今 河南师范大学 化学化工学院 历任讲师、副教授、教授(破格)

研究领域

1、手性亲核催化剂的设计及应用 2、手性吡啶配体的设计及应用 3、手性核苷的不对称合成

近期论文

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Tao Wei, Han-Le Wang, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Enantioselective construction of stereogenic-at-sulfur(IV) centers via catalytic acyl transfer sulfinylation, Nature Chemistry, 2024, https://doi.org/10.1038/s41557-024-01522-z Hai-Xia Wang, Chun Yang, Bai-Yu Xue, Ming-Sheng Xie*, Yin Tian*, Cheng Peng, and Hai-Ming Guo* Design of C1-symmetric tridentate ligands for enantioselective dearomative [3 + 2] annulation of indoles with aminocyclopropanes, Nat. Commun. 2023, 14, 2270. Xing-Yu Wang, Xiao-Bing Wang, Yin Tian*, Cheng Peng, Ming-Sheng Xie*, and Hai-Ming Guo* Cobalt-Catalyzed Asymmetric Dearomative [3 + 2] Annulation of Quinolines, Isoquinolines, and Pyridines,ACS Catal.2023, 13, 11528−11540. Xiao-Bing Wang, Yin Tian, Li Zhou, Ming-Sheng Xie*, Gui-Rong Qu, and Hai-Ming Guo, Rational Design of Chiral Tridentate Ligands: Bifunctional Cobalt(II) Complex/Hydrogen Bond for Enantioselective Michael Reactions, Org. Lett.2022, 24 (21), 3861-3866. Bai-Yu Xue, Chen-Ying Hou, Xiao-Bing Wang, Ming-Sheng Xie*, and Hai-Ming Guo*, Asymmetric synthesis of 7-membered-ring-bridged 3,4-fused tricyclic indoles via Friedel–Crafts alkylation/annulation, Org. Chem. Front. 2023, 10(8), 1910-1914. Ming-Sheng Xie*, Bin Huang, Ning Li, Yin Tian*, Xiao-Xia Wu, Yun Deng, Gui-Rong Qu, and Hai-Ming Guo* Rational Design of 2-Substituted DMAP-N-oxides as Acyl Transfer Catalysts: Dynamic Kinetic Resolution of Azlactones.J. Am. Chem. Soc. 2020, 142(45), 19226-19238.(Highlight by Synfacts和X-MOL) Ming-Sheng Xie,* Ye-Fei Zhang, Meng Shan, Xiao-Xia Wu, Gui-Rong Qu, and Hai-Ming Guo*, Chiral DMAP-N-Oxides as Acyl Transfer Catalysts: Design, Synthesis, and Application in Asymmetric Steglich Rearrangement, Angew. Chem. Int. Ed. 2019, 58(9), 2839-2843 (Highlight by 《有机化学》和X-MOL). Ming-Sheng Xie*, Meng Shan, Ning Li, Yang-Guang Chen, Xiao-Bing Wang, Xuan Cheng, Yin Tian*, Xiao-Xia Wu, Yun Deng, Gui-Rong Qu, and Hai-Ming Guo* Chiral 4-Aryl-Pyridine-N-oxide Nucleophilic Catalysts: Design, Synthesis, and Application in Acylative Dynamic Kinetic Resolution. ACS Catalysis, 2022, 12, 877-891. (IF:13.084) Ming-Sheng Xie*, Ning Li, Yin Tian*, Xiao-Xia Wu, Yun Deng, Gui-Rong Qu, and Hai-Ming Guo* Dynamic Kinetic Resolution of Carboxylic Esters Catalyzed by Chiral PPY-N-oxides: Synthesis of Nonsteroidal Anti-Inflammatory Drugs and Mechanistic Insights, ACS Catalysis, 2021, 11, 8183-8196. (IF: 13.084) Lei Cao, Xing-Ping Zhang, Ming-Sheng Xie,* and Hai-Ming Guo Cu-Catalyzed N-Arylation of Prolinamides: Access to Enantioenriched DMAP Analogues and Its Application in Black Rearrangement, J. Org. Chem.2023, 88(1), 341-346. Min Yang, Yu-Lin Gao, Ming-Sheng Xie,* and Hai-Ming Guo* ArPNO-catalyzed acylative kinetic resolution of tertiary alcohols: access to 3-hydroxy-3-substituted oxindoles, Org. Biomol. Chem., 2022, 20(32), 6351-6355. Meng Shan, Tao Liang, Ye-Fei Zhang, Ming-Sheng Xie,* Gui-Rong Qu, and Hai-Ming Guo* Enantioselective rearrangement of indolyl carbonates catalyzed by chiral DMAP-N-oxides, Org. Chem. Front. 2019, 6(23), 3874-3878. Huifang Zhang, Mingsheng Xie,* Guirong Qu, and Junbiao Chang* Dynamic Kinetic Resolution of α-Purine Substituted Alkanoic Acids: Access to Chiral Acyclic Purine Nucleosides, Org. Lett. 2019, 21(1), 120-123. Ming-Sheng Xie,* Yang-Guang Chen, Xiao-Xia Wu, Gui-Rong Qu, and Hai-Ming Guo* Asymmetric Synthesis of Chiral Acyclic Purine Nucleosides Containing a Hemiaminal Ester Moiety via Three-Component Dynamic Kinetic Resolution, Org. Lett. 2018, 20(4), 1212-1215. Hai-Xia Wang, Wen-Peng Li, Mi-Mi Zhang, Ming-Sheng Xie*, Gui-Rong Qu, and Hai-Ming Guo*,Synthesis of chiral pyrimidine-substituted diester D–A cyclopropanes via asymmetric cyclopropanation of phenyliodonium ylides, Chem. Commun. 2020, 56(78), 11649-11652. Ming-Sheng Xie, Guo-Feng Zhao, Tao Qin, Yong-Bo Suo, Gui-Rong Qu, and Hai-Ming Guo*, Thiourea participation in [3+2] cycloaddition with donor–acceptor cyclopropanes: a domino process to 2-amino-dihydrothiophenes, Chem. Commun. 2019, 55(11), 1580-1583. Ke-Xin Huang, Ming-Sheng Xie,* Qi-Ying Zhang, Gui-Rong Qu, and Hai-Ming Guo*, Enantioselective Synthesis of Carbocyclic Nucleosides via Asymmetric [3 + 2] Annulation of α-Purine-Substituted Acrylates with MBH Carbonates, Org. Lett.2018, 20(2), 389-392. Tao Qin, Jian-Ping Li, Ming-Sheng Xie,* Gui-Rong Qu, and Hai-Ming Guo*, Synthesis of Chiral Acyclic Nucleosides by Sharpless Asymmetric Dihydroxylation: Access to Cidofovir and Buciclovir, J. Org. Chem.2018, 83(24), 15512-15523. Ming-Sheng Xie,* Xuan Cheng (成轩,本科生), Yang-Guang Chen, Xiao-Xia Wu, Gui-Rong Qu, and Hai-Ming Guo*, Efficient synthesis of tetrazole hemiaminal silyl ethers via three-component hemiaminal silylation, Org. Biomol. Chem. 2018, 16(38), 6890-6894. Mingsheng Xie, Xiaohua Liu, Xiaoxia Wu, Yunfei Cai, Lili Lin and Xiaoming Feng*, Catalytic Asymmetric [8+2] Cycloaddition: Synthesis of Cycloheptatriene-Fused Pyrrole Derivatives,Angew. Chem. Int. Ed. (2013), 52, 5604-5607. Mingsheng Xie, Xiaohong Chen, Yin Zhu, Bo Gao, Lili Lin, Xiaohua Liu and Xiaoming Feng*,Asymmetric Three-Component Inverse Electron-Demand Aza-Diels–Alder Reaction: Efficient Synthesis of Ring-Fused Tetrahydroquinolines,Angew. Chem. Int. Ed. (2010), 49, 3799-3801. 谢明胜, 武晓霞, 王刚, 林丽丽, 冯小明*, 催化不对称[8+2]环加成反应构建环庚三烯并吡咯烷-3,3’-吲哚酮,化学学报,2014,72, 856-861. Mingsheng Xie, Xiaohua Liu, Yin Zhu, Xiaohu Zhao, Yong Xia, Lili Lin and Xiaoming Feng*, Asymmetric Synthesis of Tetrahydroquinolines with Quaternary Stereocenters via Povarov Reaction, Chemistry–A European Journal (2011), 17, 13800-13805.

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