Mohammed, Afzal - Aston University - School of Life & Health Sciences, Pharmacy

个人简介

PhD, Aston University (Supervisor, Prof Yvonne Perrie) (2004) MSc Sheffield Hallam University (2001) Bachelor of Pharmacy (1999) 2016 - present: Chair in Pharmaceutics 2015 - 2016: Reader in Pharmaceutics 2011- 2015 : Senior Lecturer in Pharmaceutics, Aston University 2007- 2011: Lecturer in Pharmaceutics, Aston University 2004-2007: Research Fellow, Aston University (PI, Prof Yvonne Perrie).

研究领域

Formulation development and optimization of orally disintegrating tablets Formulation and stability testing of oral liquid nano medicines Understanding the gene expression profiling of drug delivery systems using microarrays Evaluation of gene expression changes during oral drug absorption in vitro

近期论文

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Hamad Alyami, Jasdip Koner, Eman Z. Dahmash, James Bowen, David Terryand Afzal R. Mohammed* (2016) Micro particle surface layering through dry coating: impact of moisture content and process parameters on the properties of orally disintegrating tablets. Journal of Pharmacy and Pharmacology (Accepted) Hamad Alyami, Eman Dahmash, Fahad Alyami, Dania Dahmash, Chi Huynh, David Terry, Afzal R Mohammed. (2016)Dosage form preference consultation study in children and young adults: paving the way for patient centred and patient informed dosage form development. European Journal of Hospital Pharmacy (Accepted). Iyire A, Alayedi M, Mohammed AR* (2016) Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers. Nature Scientific Reports 1; 6: 32498. Jasdip Koner, Ali RajabiSiahboomi, James Bowen, Dan Kirby, Yvonne Perrie and Afzal R Mohammed* (2016) A holistic and multievidence study to understand the fragmentation behaviour of mannitol. Nature Scientific Reports5,12, 16352. Thomas J. Dennison, Julian Smith, Michael P. Hofmann, Charlotte E. Bland, Raj K. Badhan, Ali Al-Khattawi and Afzal R. Mohammed* (2016)Design of Experiments to Study the Impact of Process Parameters on Droplet Size and Development of Non-Invasive Imaging Techniques in Tablet Coating. PLOS ONE 11(8):e0157267 Eman Dahmash and Afzal R Mohammed* (2016) Characterisation and surface profiling techniques fr composite particles produced by dry particle coating in pharmaceutical drug delivery. Drug Discovery Today 21(4):550-61. Eman Dahmash and Afzal R Mohammed (2015) Functionalised particles using dry powder coating in pharmaceutical drug delivery: promises and challenges. Expert opinion on drug delivery (Accepted). Amr ElShaer, Waseem Kaialy, Noreen Akhtar, Affiong Iyire, Tariq Hussain, Raid Alany and Afzal R Mohammed (2015) A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets. European Journal of Pharmaceutics and Biopharmaceutics (Accepted). Ali Al-Khattawi, Jasdip Koner, Peter Rue, Dan Kirby, Yvonne Perrie, Ali Rajabi-Siahboomi, Afzal R Mohammed (2015) A pragmatic approach for engineering porous mannitol and mechanistic evaluation of particle performance. European Journal of Pharmaceutics and Biopharmaceutics (Accepted). Craig Russell, Sumyra Begum, Yasar Hussain, Majad Hussain, David Huen, Ayesha S Rahman, Yvonne Perrie and Afzal R Mohammed. (2015) Paediatric Drug Development of Ramipril: Reformulation, In Vitro and In Vivo Evaluation. Journal of Drug Targeting (Accepted). Ali Al-khattawi, Hamad Alyami, Bill Townsend, Xianghong Maand Afzal R Mohammed (2014) Evidence-Based Nanoscopic and Molecular Framework for Excipient Functionality in Compressed Orally Disintegrating Tablets. PLOS ONE – Accepted. Ali Al-khattawi and Afzal R Mohammed (2014) Challenges and Emerging Solutions in the Development of Compressed Orally Disintegrating Tablets. Expert Opinion On Drug Discovery – Accepted. Amr ElShaer, Peter Hanson, and Afzal R Mohammed (2014) A novel concentration dependent amino acid ion pair strategy to mediate drug permeation using indomethacin as a model insoluble drug. European Journal of Pharmaceutical Sciences -Accepted Ali Al-Khattawi, Affiong Iyire, Tom Dennison, Eman Dahmash, Clifford J Bailey, Julian Smith, Peter Rue, Afzal R Mohammed (2014) Systematic Screening of Compressed ODT Excipients: Cellulosic Versus Non -Cellulosic. Current Drug Delivery (Accepted) Ali Al-khattawi and Afzal R Mohammed (2014) Excipients in Medicines for Children: Scientific and Regulatory Paradigms. European Pharmaceutical Review (Accepted) Ali Al-khattawi and Afzal R Mohammed (2013) Compressed Orally Disintegrating Tablets: Excipients Evolution and Formulation Strategies. Expert Opinion in Drug Delivery. 10, 5, 651 - 663. Hesham Tawfeek, Evans AR, Ifitkhar A, Afzal Mohammed, Shabir A, Somavarapu S, Gillian Hutcheon, Imran Saleem (2013) Dry powder inhalation of macromolecules using novel PEG-co-polyester microparticle carriers International Journal of Pharmaceutics. Accepted. Craig Russell, Ayesha Rahman and Afzal R Mohammed (2013) Application of genomics, proteomics and metabolomics in drug discovery, development and clinic. Therapeutic Delivery. 4 (3) 395 - 413. Amr ElShaer, Defang Ouyang, Peter Hanson, and Afzal R Mohammed (2013).Application of molecular simulation studies in the development of amino acid based pharmaceutical salts of ciprofloxacin. Journal of Pharmaceutics and Drug Delivery Research.Accepted Amr ElShaer, Peter Hanson and Afzal R Mohammed (2013) A systematic and mechanistic evaluation of aspartic acid as a filler for directly compressed tablets containing trimethoprim and trimethoprim aspartate. European Journal of Pharmaceutics and Biopharmaceutics. 83, 3, 468 - 476.