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个人简介

教育经历: 2010/10–2014/2 德国哥廷根大学化学学院,有机化学,博士,导师:Lutz Ackermann 教授 2007/9–2010/7 郑州大学化学系,有机化学,硕士,导师:朱志兀教授 2003/9–2007/7 郑州大学化学系,化学,学士 科研与学术工作经历: 2014/7– 华侨大学生物医学学院讲师、副教授,硕士生导师 主讲课程: 《有机化学》(本科生),《有机化学实验》(本科生),《医用化学(有机部分)》,《医用化学实验(有机部分)》;《化学史话》(校通识课程);《功能有机分子的设计与合成》(研究生),《高等有机化学》(研究生),《化学药物合成》(研究生)。 主持科研项目: 1. 烯基叠氮参与的氮杂环医药分子骨架构筑(2018C073R),泉州市科技计划项目,20 万。 2. 福建省高校杰出青年科研人才培育计划,4 万。 3. 膦-磷叶立德双齿配体介导的 C–H 键官能团化反应研究(21602064),国家自然科学基金青年项目,20 万。 4. 基于过渡金属催化 C–H 键活化的氧化偶联反应研究(2015J01056),福建省自然科学基金面上项目,4 万。 5. 可移去/修饰导向基作用下的 C–H 键功能化反应研究(JA15032),福建省中青年教师教育科研项目,2 万。 6. 易修饰导向基作用下的直接 C–H 键活化反应研究(ZQN-PY317),中央高校基本科研业务费,40 万。 7. 基于金属催化直接 C–H 键功能团化反应研究(16BS106),华侨大学科研启动基金,6 万。 入选人才计划项目: 1. 福建省高校杰出青年科研人才培育计划(2018) 2. 泉州市“海纳百川”高端人才聚集计划(2015) 授权发明专利: 1. 王连会,崔秀灵,揭亮华, 一种N-(2-吡啶/嘧啶基)吲哚衍生物的制备方法,2018.1.8,中国,ZL201810017134.2。

研究领域

有机合成与药物合成;有机合成方法学。

近期论文

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23. Z. Shi, L. Wang*, Z. Yang, L. Jie, X. Liu, X. Cui*, Tandem construction of indole-fused phthalazines from (2-alkynylbenzylidene)hydrazines under metal-free conditions. J. Org. Chem., 2020, 85, 3029−3040. 22. W. Fu, L. Wang*, Z. Yang, J.-S. Shen, F. Tang, J. Zhang, X. Cui*, Facile access to versatile aza-macrolides through iridium-catalysed cascade allyl-amination/macrolactonization. Chem. Commun., 2020, 56, 960−963. 21. Z. Shi, L. Wang*, X. Cui*, Recent advances in the I2-catalyzed C−H bond functionalizations. Chin. J. Org. Chem., 2019, 39, 1596−1612. (In Chinese) 20. L. Jie, L. Wang*, D. Xiong, Z. Yang, D. Zhao, X. Cui*, Synthesis of 2‑arylindoles through Pd(II)-catalyzed cyclization of anilines with vinyl azides. J. Org. Chem., 2018, 83, 10974−10984. 19. D. Xiong, L. Wang*, L. Jie, Z. Yang, L. Li, X. Cui*, Rhodium-catalyzed mild C7-amination of indolines with nitrosobenzenes. ChemistrySelect, 2018, 3, 13497–13500. 18. L. Wang, D. Xiong, L. Jie, C. Yu, X. Cui*, Rhodium-catalyzed oxidative homologation of N-pyrimidyl indolines with alkynes via dual C–H activation: facile synthesis of benzo[g]indolines, Chin. Chem. Lett., 2018, 29, 907–910. 17. L. Wang, Y. Yu, M. Yang, C. Kuai, D. Cai, J. Yu, X. Cui*, Rhodium-catalyzed synthesis of multiaryl-substituted naphthols via a removable directing group. Adv. Synth. Catal., 2017, 359, 3818−3825. 16. L. Wang, Z. Yang, M. Yang, M. Tian, C. Kuai, X. Cui*, Facile route to ortho-hydroxyanilnes through an IrIII-catalyzed direct C–H amidation of 2-phenoxypyridines. Chem. Asian J., 2017, 12, 2634–2643. 15. L. Wang, Z. Yang, M. Yang, R. Zhang, C. Kuai, X. Cui*, Iridium-catalyzed direct C–H amidation of anilines with sulfonyl azides: easy access to 1,2-diaminobenzenes. Org. Biomol. Chem., 2017, 15, 8302−8307. 14. L. Xu, L. Wang, Y. Feng, Y. Li, L. Yang, X. Cui*, Iridium(III)-catalyzed one-pot access to 1,2-disubstituted benzimidazoles starting from imidamides and sulfonyl azides. Org. Lett., 2017, 19, 4343−4346. 13. C. Kuai, L. Wang, B. Li, Z. Yang, X. Cui*, Cobalt-catalyzed selective synthesis of isoquinolines using picolinamide as a traceless directing group. Org. Lett., 2017, 19, 2102−2105. 12. C. Kuai, L. Wang, H. Cui, J. Shen, Y. Feng, X. Cui*, Efficient and selective synthesis of (E)-enamides via Ru(II)-catalyzed hydromidation of internal alkynes. ACS Catal., 2016, 6, 186–190. 11. M. Wei, L. Wang, Y. Li, X. Cui*, Iridium-catalyzed direct ortho-C–H amidation of benzoic acids with sulfonylazides. Chin. Chem. Lett., 2015, 26, 1336–1340. 10. J. Mo, L. Wang, X. Cui*, Rhodium(III)-catalyzed C–H activation/alkyne annulation by weak coordination of peresters with O–O bond as an internal oxidant. Org. Lett., 2015, 17, 4960–4963. 9. J. Mo, L. Wang, Y. Liu, X. Cui*, Transition-metal-catalyzed direct C–H functionalization under external-oxidant-free conditions. Synthesis, 2015, 47, 439–459. (Invited review) 8. L. Wang, K. Rauch, A. V. Lygin, S. I. Kozhushkov, L. Ackermann*, Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C–H bond functionalization in water: synthesis of ethyl (E)-3-(2-acetamido-4-methylphenyl)acrylate. Org. Synth., 2015, 92, 131–147. 7. M. Schinkel, L. Wang, K. Bielefeld, L. Ackermann*, Ruthenium(II)-catalyzed C(sp(3))–H alpha-alkylation of pyrrolidines. Org. Lett., 2014, 16, 1876–1879. 6. L. Wang, L. Ackermann*, Ruthenium-catalyzed ortho-C–H halogenations of benzamides. Chem. Commun., 2014, 50, 1083–1085. 5. L. Wang, L. Ackermann*, Versatile pyrrole synthesis through ruthenium(II)-catalyzed alkene C–H bond functionalization on enamines. Org. Lett., 2013, 15, 176–179. 4. L. Ackermann*, L. Wang, A. V. Lygin, Ruthenium-catalyzed aerobic oxidative coupling of alkynes with 2-aryl-substituted pyrroles. Chem. Sci., 2012, 3, 177–180. 3. L. Ackermann*, L. Wang, R. Wolfram, A. V. Lygin, Ruthenium-catalyzed oxidative C–H alkenylations of anilides and benzamides in water. Org. Lett., 2012, 14, 728–731. 2. L. Wang, X. Cui*, J. Li, Y. Wu, Z. Zhu, Y. Wu*, Synthesis of biaryls through a one-pot tandem borylation/Suzuki-Miyaura cross-coupling reaction catalyzed by a palladacycle. Eur. J. Org. Chem., 2012, 595–603. 1. L. Wang, J. Li, X. Cui*, Y. Wu, Z. Zhu, Y. Wu*, Cyclopalladated ferrocenylimine as efficient catalyst for the syntheses of arylboronate esters. Adv. Synth. Catal., 2010, 352, 2002–2010.

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