Greenhill , Stuart - Aston University - School of Life & Health Sciences, Pharmacy

个人简介

BSc with First Class Honours in Pharmacology, University of Edinburgh, 2004 PhD in Neuropharmacology, University of Bath, 2008 2010 – 2016 Post-doctoral Research, Cardiff University 2016 – date: Lecturer in Neuroscience, Aston University

研究领域

My research is focussed around the mechanisms of synaptic plasticity in physiological and disease states. By using a combination of electrophysiology, functional imaging and molecular biology, we can probe the receptors and cellular processes that cause neural circuits and synapses to alter their strengths and functions in response to the changing stimulus of the outside world. This natural process would appear to be subject to critical developmental periods and be disrupted in several psychiatric and neurological conditions, so further study of its function and dysfunction is crucial to our understanding of neuroscience and psychiatry.

近期论文

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Greenhill, SD, Ranson, A & Fox, K 2015, 'Hebbian and homeostatic plasticity mechanisms in regular spiking and intrinsic bursting cells of cortical layer 5' Neuron, vol. 88, no. 3, pp. 539-552,10.1016/j.neuron.2015.09.025 Greenhill, SD, Juczewski, K, de Haan, AM, Seaton, G, Fox, K & Hardingham, NR 2015, 'Adult cortical plasticity depends on an early postnatal critical period' Science, vol. 349, no. 6246, pp. 424-427,10.1126/science.aaa8481 Greenhill, SD, Chamberlain, SEL, Lench, A, Massey, PV, Yuill, KH, Woodhall, GL & Jones, RSG 2014, 'Background synaptic activity in rat entorhinal cortex shows a progressively greater dominance of inhibition over excitation from deep to superficial layers' PLoS ONE, vol. 9, no. 1, e85125,10.1371/journal.pone.0085125 Greenhill, SD, Massey, P, Morgan, N, Woodhall, G & Jones, RSG 2012, 'Ethosuximide modifies network excitability in the rat entorhinal cortex via an increase in GABA release' Neuropharmacology, vol. 62, no. 2, pp. 807-814,10.1016/j.neuropharm.2011.09.006 Greenhill, SD & Jones, RSG 2010, 'Diverse antiepileptic drugs increase the ratio of background synaptic inhibition to excitation and decrease neuronal excitability in neurones of the rat entorhinal cortexin vitro' Neuroscience, vol. 167, no. 2, pp. 456-474,10.1016/j.neuroscience.2010.02.021 Harmar, AJ, Hills, RA, Rosser, EM, Jones, M, Buneman, OP, Dunbar, DR, Greenhill, SD, Hale, VA, Sharman, JL, Bonner, TI, Catterall, WA, Davenport, AP, Delagrange, P, Dollery, CL, Foord, SM, Gutman, GA, Laudet, V, Neubig, RR, Ohlstein, EH, Olsen, RW, Peters, J, Pin, J-P, Ruffolo, RR, Searls, DB, Wright, MW & Spedding, M 2009, 'IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels' Nucleic Acids Research, vol. 37, no. Suppl.1, pp. D680-D685,10.1093/nar/gkn728