个人简介
广东省农业科技特派员;近年来,主要从事鱼类糖脂营养及代谢、养殖鱼类肌肉品质调控、以及非蛋白能量饲料高效利用技术开发等方面的科研教学工作。主持包括国家自然科学基金青年项目、广州市基础研究计划基础与应用基础研究项目、江苏省研究生创新工程项目在内的科研课题3项,参与省部级课题5项;以第一作者或通讯作者身份在《Aquaculture》、《British Journal of Nutrition》、《Frontiers in Physiology》、《Endocrine Connections》、《General and Comparative Endocrinology》、《Fish Physiology and Biochemistry》、《Aquaculture Research》、《Aquaculture Reports》、《Fish and Shellfish Immunology》、《Comparative Biochemistry and Physiology Part A》、《水产学报》、《中国水产科学》等国内外12本著名期刊上发表论文20余篇,其中SCI论文14篇;担任《Aquaculture》、《Aquaculture Nutrition》、《Aquaculture Research》、《Aquaculture Reports》、《Fish and Shellfish Immunology》、《Fish Physiology and Biochemistry》等SCI期刊审稿人。
工作经历
2019/11–至今,华南农业大学海洋学院,讲师
教育经历
2013/09–2019/09,南京农业大学(硕博连读),水产动物营养与饲料科学,博士;
2018/08–2019/08,挪威海洋研究所(Institute of Marine Research)访学;
2009/09–2013/06,沈阳农业大学,水产养殖学,学士.
主持或参加省部级科研项目(课题):
1.国家自然科学基金青年科基金项目,TXNIP在高糖诱导团头鲂肝细胞焦亡中的调控机制研究,2021.1-2023.12,主持;
2.广州市基础研究计划基础与应用基础研究项目,AMPK/Drp1通路在高糖诱导罗非鱼肝细胞线粒体功能损伤中的作用机制研,2022.4-2024.3,主持;
3.江苏省研究生培养创新工程项目,Drp1基因对高糖胁迫团头鲂线粒体分裂异常的作用机制研究,2018.5-2019.5,主持;
4.国家大宗淡水鱼类产业技术体系项目,团头鲂营养需求研究,参与;
5.国家自然科学基金面上项目,GPR40介导的团头鲂β-细胞胰岛素分泌及脂性凋亡的调控机制,2015.1-2018.12,参与;
6.国家自然科学基金面上项目,转录辅激活因子PGC1β介导的高糖诱导团头鲂线粒体功能损伤机制研究,2019.1-2021.12,参与;
7.广东省基础与应用基础研究基金面上项目,饲料脂肪酸组成提升罗非鱼肌肉品质的机制研究,2021.1-2023.12,参与;
8.江苏省青年基金项目,高糖胁迫下团头鲂AMPK通路磷酸化水平分析及二甲双胍对其的调控研究,2014.1-2017.12,参与;
专利申请
(1) 一种提高水产动物糖利用率的调控组合物、制备方法与应用. 发明专利,202010573349.X(1/3).
(2) 一种高效水产糖代谢调控组合物及其制备方法与应用. 发明专利,201811316474.1(2/4).
(3) 一种改善鱼体糖类耐受性的调控组合物及其制备方法. 发明专利,ZL201510811938.6(3/5).
近期论文
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一、SCI期刊论文
(1) Xu Chao, et al. Interactions between dietary carbohydrate and thiamine: Implications on the growth performance and intestinal mitochondrial biogenesis and function of Megalobrama amblycephala. British Journal of Nutrition, 2021, 1–14.
(2) Xu Chao, et al. Benfotiamine ameliorates high-carbohydrate diet-induced hepatic oxidative stress, inflammation and apoptosis in Megalobrama amblycephala.Aquaculture Research, 2021, DOI:10.1111/are.15164.
(3) Xu Chao, et al.Restricted feeding benefits the growth performance and glucose homeostasis of blunt snout bream Megalobrama amblycephala fed high-carbohydrate diets. Aquaculture Reports, 2020, 18: 100513.
(4) Xu Chao, et al. Regulation of growth, intestinal microflora composition and expression of immune-related genes by dietary supplementation of Streptococcus faecalis in blunt snout bream (Megalobrama amblycephala).Fish and Shellfish Immunology, 2020, 105: 195–202.
(5) Li Meng-Meng#, Xu Chao#, et al. Effects of dietary n-3 highly unsaturated fatty acids levels on growth, lipidmetabolism and innate immunity in juvenile golden pompano (Trachinotus ovatus). Fish and Shellfish Immunology, 2020, 105: 177–185.
(6) Ma Yong-Cai#, Xu Chao#, et al.Diet with a high proportion replacement of fishmeal by terrestrial compound protein displayed better farming income and environmental benefits in the carnivorous marine teleost (Trachinotus ovatus). Aquaculture Reports, 2020, 18:100449.
(7) Xu Chao, et al.Feeding restriction alleviates high carbohydrate diet-induced oxidative stress and inflammation of Megalobrama amblycephala by activating the AMPK-SIRT1 pathway. Fish and Shellfish Immunology, 2019, 92, 637–648.
(8) Xu Chao, et al. Metformin improves the glucose homeostasis of Wuchang bream fed high-carbohydrate diets: a dynamic study.Endocrine Connections, 2019, 8: 1-13.
(9) Xu Chao, et al.Interactions between dietary carbohydrate and metformin: implications on energy sensing, insulin signaling pathway, glycolipid metabolism and glucose tolerance in blunt snout bream Megalobrama amblycephala. Aquaculture, 2018, 483: 183–195 (Web of Science高引论文).
(10) Xu Chao, et al. Benfotiamine, a Lipid-soluble analog of Vitamin B1, improves the mitochondrial biogenesis and function in blunt snout bream fed high-carbohydrate diets by promoting the AMPK/PGC-1β/NRF-1 Axis.Frontiers in Physiology, 2018, 9: 1079.
(11) Xu Chao, et al.AMP-activated protein kinase α1 in Megalobrama amblycephala: Molecular characterization and the transcriptional modulation by nutrient restriction and glucose and insulin loadings.General and Comparative Endocrinology, 2018, 267: 66-75.
(12) Xu Chao, et al.Long-term administration of benfotiamine benefits the glucose homeostasis of juvenile blunt snout bream Megalobrama amblycephala, fed a high-carbohydrate diet. Aquaculture, 2017, 470: 74-83.
(13) Xu Chao, et al.Molecular characterization of AMP-activated protein kinase α2 from herbivorous fish Megalobrama amblycephala and responsiveness to glucose loading and dietary carbohydrate levels. Comparative Biochemistry and Physiology Part A, 2017, 208: 24–34.
(14) Xu Chao, et al. Feeding rates affect growth, intestinal digestive and absorptive capabilities and endocrine functions of juvenile blunt snout bream Megalobrama amblycephala. Fish Physiology and Biochemistry, 2016, 42: 689-700.
二、中文核心期刊论文
(1) 徐超*.团头鲂PGC1α基因克隆及其对营养限制、高糖营养和葡萄糖负荷的响应.水产学报, 2021 (接收).
(2)徐超, 等. 团头鲂PGC1β基因克隆及高糖胁迫、葡萄糖和胰岛素负荷对其mRNA表达的影响.中国水产科学, 2021 (接收).
(3)徐超, 等.苯磷硫胺对饲喂高糖饲料团头鲂血浆生化指标及肝糖脂代谢的影响.中国水产科学, 2021, 28(2): 186-194.
(4)徐超, 等.不同投饵率对团头鲂幼鱼血脂水平及脂肪代谢相关基因表达的影响. 水产学报, 2016, 40: 1732-1741.
(5)徐超, 等. 水产动物营养与饲料学实验教学改革初探. 科技创新导报, 2020, 27: 174-176.