孙加节 - 华南农业大学 - 动物科学学院

个人简介

U.S. Department of Agriculture与西北农林科技大学联合培养博士工作经历 2013年-2015年，美国农业部农业研究局，访问学者 2015年-至今，华南农业大学动物科学学院科研项目 1. 国家自然科学基金青年项目，CircRNA作为ceRNA参与miR-423-5p调控猪骨骼肌纤维发育的机制研究，主持 2. 广东省自然科学基金博士科研启动项目，猪高瘦肉率相关miRNAs鉴定及其调控肌细胞增殖与分化研究，主持 3. 广东省普通高校省级特色创新类项目（自然科学类），奶水牛泌乳相关miRNAs鉴定及其靶基因验证研究，主持 4. 亚热带农业生物资源保护与利用国家重点实验室开放课题基金项目，主持 5. 国家重点研发计划，环境因素对家畜泌乳健康的影响机制，项目骨干 6. 国家重点研发计划，优质肉牛高效安全养殖技术应用与示范，项目骨干教学活动《动物生物化学》、《饲料生物技术》、《动物营养组学》我的团队张永亮教授，习欠云教授，陈婷博士，罗君谊实验师。

研究领域

（1）环境应激与乳品质调控；（2）肉品质调控机制及营养干预；（3）饲料生物技术

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Zhu, Y. L., Chen, T., Xiong, J. L., Wu, D., Xi, Q. Y., Luo, J. Y., Jiajie Sun & Zhang, Y. L. (2018). miR-146b Inhibits Glucose Consumption by Targeting IRS1 Gene in Porcine Primary Adipocytes. International journal of molecular sciences, 19(3), 783. 2. Zhang, H., Qi, Q., Chen, T., Luo, J., Xi, Q., Jiang, Q., Jiajie Sun & Zhang, Y. (2018). Age-Related Changes in MicroRNA in the Rat Pituitary and Potential Role in GH Regulation. International journal of molecular sciences, 19(7). 3. Jiajie Sun, Meiying Xie, Zhipeng Huang, Hongyi Li, Ting chen, Qianyun Xi, Tongshan Wu, Yongliang Zhang. Integrated analysis of non-coding RNA and mRNA expression profiles of 2 pig breeds differing in muscle traits. Journal of animal science, 2017, 95(3), 1092-1103. 4. Jiajie Sun, Bin Zeng, Zujing Chen, Shijuan Yan, Wenjie Huang, Baoli Sun, Qian He, Xiaoyan Chen, Ting Chen, Qingyan Jiang, Qianyun Xi, Yongliang Zhang. Characterization of faecal microbial communities of dairy cows fed diets containing ensiled Moringa oleifera fodder. Scientific reports, 2017, 7, 41403. 5. Jiajie Sun, Kshama Aswath, Steven G. Schroeder, John D. Lippolis, Timothy A. Reinhardt, Tad S. Sonstegard. MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection. BMC genomics, 2015, 16(1), 806. 6. Jiajie Sun, Tad S Sonstegard, Congjun Li, Yongzheng Huang, Zhuanjian Li, Xianyong Lan, Chunlei Zhang, Chuzhao Lei, Xin Zhao, Hong Chen. Altered microRNA expression in bovine skeletal muscle with age. Animal genetics, 2015, 46(3): 227-238. 7. Jiajie Sun, Yang Zhou, Hanfang Cai, Xianyong Lan, Chuzhao Lei, Xin Zhao, Chunlei Zhang, and Hong Chen. Discovery of novel and differentially expressed microRNAs between fetal and adult backfat in cattle. PloS one, 2014, 9(2): e90244. 8. Jiajie Sun, Bowen Zhang, Xianyong Lan, Chunlei Zhang, Chuzhao Lei, and Hong Chen. Comparative Transcriptome Analysis Reveals Significant Differences in MicroRNA Expression and Their Target Genes between Adipose and Muscular Tissues in Cattle. PloS one, 2014, 9(7): e102142. 9. Jiajie Sun, Liming Shan, Chunlei Zhang, and Hong Chen. Haplotype combination of the bovine PCSK1 gene sequence variants and association with growth traits in Jiaxian cattle. Journal of genetics, 2014, 93(3): e123-129. 10. Jiajie Sun, Mijie Li, Zhuanjian Li, Jing Xue, Xianyong Lan, Chunlei Zhang, Chuzhao Lei, and Hong Chen. Identification and profiling of conserved and novel microRNAs from Chinese Qinchuan bovine longissimus thoracis. BMC genomics, 2013, 14(1): 42. 11. Jiajie Sun, Jinlong Zhu, Jing Xue, Chunlei Zhang, Xianyong Lan, Chuzhao Lei, and Hong Chen. Haplotype combinations of AdPLA gene polymorphisms associate with growth traits in Chinese cattle. Molecular biology reports, 2012, 39(6): 7069-7076. 12. Jiajie Sun, Jing Xue, Chunlei Zhang, Xianyong Lan, Chuzhao Lei, and Hong Chen. Haplotype combination of the caprine PC1 gene sequence variants and association with growth traits in Chinese Haimen breed. J Genet, 2012, 91(1): E54-E59. 13. Jiajie Sun, Yuan Gao, Dong Liu, Wei Ma, Jing Xue, Chunlei Zhang, Xianyong Lan, Chuzhao Lei, and Hong Chen. Haplotype combination of the bovine INSIG1 gene sequence variants and association with growth traits in Nanyang cattle. Genome, 2012, 55(6): 429-436. 14. Jiajie Sun, Chunlei Zhang, Xianyong Lan, Chuzhao Lei, and Hong Chen. Exploring polymorphisms and associations of the bovine MOGAT3 gene with growth traits. Genome, 2011, 55(1): 56-62. 15. Jiajie Sun, Qijiang Jin, Chunlei Zhang, Xingtang Fang, Chuanwen Gu, Chuzhao Lei, Juqiang Wang, and Hong Chen. Polymorphisms in the bovine ghrelin precursor (GHRL) and Syndecan-1 (SDC1) genes that are associated with growth traits in cattle. Molecular biology reports, 2011, 38(5): 3153-3160. 16. Chen Zhongqi, Jiajie Sun, Zhuanjian Li, Xianyong Lan, Chunlei Zhang, Yujiao Qu, Yanli Liu, Xingtang Fang, Chuzhao Lei, and Hong Chen. Novel SNPs in the caprine stearoyl-CoA desaturase (SCD) and decorin (DCN) genes that are associated with growth traits in Chinese goat breeds. Molecular biology reports, 2011, 38(5): 3121-3127. 17. Jiajie Sun, Zhang ChunLei, Fang XingTang, Lei ChuZhao, Lan XianYong, and Chen Hong. The polymorphism of bovine FIT gene and its associations with cattle (Bos taurus) growth traits. Animal Science Papers and Reports, 2011, 29(2): 99-107. 18. Jiajie Sun, Chunlei Zhang, Hong Chen, Xingtang Fang, Qijiang Jin, Danxia Chen, Xiuying Shi, and Yu Du. Two novel SNPs in coding region of the caprine Fat-inducing transcript gene and their association with growth traits. Molecular biology reports, 2010, 37(1): 485-490. 19. Jiajie Sun, Chuanwen Gu, Chunlei Zhang, Chuzhao Lei, Xingtang Fang, Qijiang Jin, Danxia Chen, Xiuying Shi, Yu Du, and Hong Chen. Association of polymorphisms of the DCN gene with growth traits in cattle. ARCHIV FUR TIERZUCHT-ARCHIVES OF ANIMAL BREEDING, 2010, 53(1): 119-121. 20. Jiajie Sun, Chunlei Zhang, Xingtang Fang, Chuzhao Lei, Xianyong Lan, and Hong Chen. Novel single nucleotide polymorphisms of the caprine PC1 gene and association with growth traits. Biochemical genetics, 2010, 48(9-10): 779-788. 21. Laercio R. Porto-Neto1, Derek M. Bickhart, Antonio J. Landaeta-Hernandez, Yuri T. Utsunomiya, Melvin Pagan, Esbal Jimenez, Peter J. Hansen, Serdal Dikmen, Steven G. Schroeder, Eui-Soo Kim, Jiajie Sun, Edward Crespo, Norman Amati, John B. Cole, Daniel Null, Jose Fernando Garcia, Antonio Reverter, William Barendse, Tad S. Sonstegard. Convergent evolution of slick coat in cattle through truncation mutations in the prolactin receptor. Frontiers in Genetics, 2018, 9, 57. 22. Bickhart Derek M, Rosen Benjamin D, Koren Sergey, Sayre Brian L, Hastie Alex R, Chan Saki, Lee Joyce, Lam Ernest T, Liachko Ivan, Sullivan Shawn T, Burton Joshua N, Huson Heather J, Nystrom John C, Kelley Christy M, Hutchison Jana L, Zhou Yang, Jiajie Sun, Crisa Alessandra, Ponce de Leon F Abel, Schwartz John C, Hammond John A, Waldbieser Geoffrey C, Schroeder Steven G, Liu George E, Dunham Maitreya J, Shendure Jay, Sonstegard Tad S, Phillippy Adam M, Van Tassell Curtis P, Smith Timothy P L. Single-molecule sequencing and chromatin conformation capture enable de novo reference assembly of the domestic goat genome, Nature genetics, 2017, 49(4), 643. 23. Lingyang Xu, Ryan J. Haasl, Jiajie Sun, Yang Zhou, Derek M. Bickhart, Junya Li, Jiuzhou Song, Tad S. Sonstegard, Curtis P. Van Tassell, Harris A. Lewin, George E. Liu. Systematic Profiling of Short Tandem Repeats in the Cattle Genome. Genome biology and evolution, 2017, 9(1), 20-31. 24. Gan Zhou, Lina Wang, Yaqiong Xu, Kelin Yang, Lv Luo, Leshan Wang, Yongxiang Li, Jiawen Wang, Gang Shu, Songbo Wang, Ping Gao, Xiaotong Zhu, Qianyun Xi, Jiajie Sun, Yongliang Zhang, Qingyan Jiang. Diversity effect of capsaicin on different types of skeletal muscle. Molecular and cellular biochemistry, 2017, 1-13. 25. Xiaojuan Wan, Songbo Wang, Jingren Xu, Lu Zhuang, Kongping Xing, Mengyuan Zhang, Xiaotong Zhu, Lina Wang, Ping Gao, Qianyun Xi, Jiajie Sun, Yongliang Zhang, Tiejun Li, Gang Shu, Qingyan Jiang. Dietary protein-induced hepatic IGF-1 secretion mediated by PPARγ activation. PloS one, 2017, 12(3), e0173174. 26. Zhuanjian Li, Xianyong Lan, Ruili Han, Jing Wang, Yongzhen Huang, Jiajie Sun, Wenjiao Guo, and Hong Chen. miR-2478 inhibits TGFβ1 expression by targeting the transcriptional activation region downstream of the TGFβ1 promoter in dairy goats. Scientific Reports, 2017, 7, 42627. 27. Ruiping Sun, Qianyun Xi, Jiajie Sun, Xiao Chen, Yanling Zhu, Dingze Ye, Ting Chen, Limin Wei, Ruisong Ye, Qingyan Jiang, Yongliang Zhang. In low protein diets, microRNA-19b regulates urea synthesis by targeting SIRT5. Scientific reports, 2016, 6, 33291. 28. Ting Chen, Meiying Xie, Jiajie Sun, Ruisong Ye, Xiao Cheng, Ruiping Sun, Limin Wei, Meng Li, Delin Lin, Qingyan Jiang, Qianyun Xi, Yongliang Zhang. Porcine milk-derived exosomes promote proliferation of intestinal epithelial cells. Scientific reports, 2016, 6, 33862. 29. Robert W. Li, Weizhong Li, Jiajie Sun, Peng Yu, Ransom L. Baldwin, Joseph F. Urban. The effect of helminth infection on the microbial composition and structure of the caprine abomasal microbiome. Scientific reports, 2016, 6, 20606. 30. Yongzhen Huang, Yujia Sun, Li Mingxun, Jing Wang, Jiajie Sun, ChunLei Zhang, and Hong Chen. Evaluation of the causality of the zinc finger BED type containing 6 gene (ZBED6) for six important growth traits in Nanyang beef cattle. Animal genetics, 2015, 46(2), 225-226. 31. Yanhong Wang, Chunlei Zhang, Xingtang Fang, Yulong Zhao, Xiaohui Chen, Jiajie Sun, Yang Zhou, Jianjin Wang, Yongan Wang, Xianyong Lan, Hong Chen. Identification and Profiling of microRNAs and Their Target Genes from Developing Caprine Skeletal Muscle. PloS one, 2014, 9(5), e96857. 32. Yang Zhou, Hanfang Cai, Yao Xu, Jiajie Sun, Xianyong Lan, Chuzhao Lei, and Hong Chen. Novel isoforms of the bovine Nuclear factor I/X (CCAAT‐binding transcription factor) transcript products and their diverse expression profiles. Animal genetics, 2014, 45(4), 581-584. 33. Yongzhen Huang, Jiajie Sun, Liangzhi Zhang, Congjun Li, James E. Womack, Zhuanjian Li, Xianyong Lan, Chuzhao Lei, Chunlei Zhang, Xin Zhao, and Hong Chen. Genome-wide DNA Methylation Profiles and Their Relationships with mRNA and the microRNA Transcriptome in Bovine Muscle Tissue （Bos taurine）. Scientific Reports, 2014, 4: 6546. 34. Liangzhi Zhang, Shangang Jia, Mingjuan Yang, Yao Xu, Congjun Li, Jiajie Sun, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, Yang Zhou, Chunlei Zhang, Xin Zhao, and Hong Chen. Detection of copy number variations and their effects in Chinese bulls. BMC Genomics, 2014, 15(1):480. 35. Yang Zhou, Jiajie Sun, Congjun Li, Yanhong Wang, Lan Li, Hanfang Cai, Xianyong Lan, Chuzhao Lei, Xin Zhao, and Hong Chen. Characterization of Transcriptional Complexity during Adipose Tissue Development in Bovines of Different Ages and Sexes. PLoS ONE, 2014, 9(7): e101261. 36. Yanhong Wang, Chunlei Zhang, Xingtang Fang, Yulong Zhao, Xiaohui Chen, Jiajie Sun, Yang Zhou, Jianjin Wang, Yongan Wang, Xianyong Lan, and Hong Chen. Identification and Profiling of microRNAs and Their Target Genes from Developing Caprine Skeletal Muscle. PLoS ONE, 2014, 9(5): e96857. 37. Liangzhi Zhang, Mingjuan Yang, Congjun Li, Yao Xu, Jiajie Sun, Chuzhao Lei, Xianyong Lan, Chunlei Zhang, and Hong Chen. Identification and genetic effect of a variable duplication in the promoter region of the cattle ADIPOQ gene. Animal Genetics, 2014, 45(2): 171-179. 38. Yang Zhou, Hanfang Cai, Yao Xu, Jiajie Sun, Xianyong Lan, Chuzhao Lei and Hong Chen. Novel isoforms of the bovine Nuclear factor I/X (CCAAT-binding transcription factor) transcript products and their diverse expression profiles. Animal Genetics, 2014, 45: 581-584. 39. Yongzhen Huang，Mingxun Li，Jing Wang，Zhaoyang Zhan，Yujia Sun，Jiajie Sun, Congjun Li，Xianyong Lan，Chuzhao Lei，Chunlei Zhang，and Hong Chen. A 5′-Regulatory Region and Two Coding Region Polymorphisms Modulate Promoter Activity and Gene Expression of the Growth Suppressor Gene ZBED6 in Cattle. PLoS ONE, 2013, 8(11): e79744. 40. Cai Hanfang, Lan Xianyong, Li Aiming, Zhou Yang, Jiajie Sun, Lei Chuzhao, and Chen Hong. SNPs of bovine HGF gene and their association with growth traits in Nanyang cattle. Research in veterinary science, 2013, 95(2): 483-488. 41. Zhuanjian Li, Xianyong Lan, Wenjiao Guo, Jiajie Sun, Yongzhen Huang, Jing Wang, Tinghua Huang, Chuozhao Lei, Xingtang Fang, and Hong Chen. Comparative Transcriptome Profiling of Dairy Goat MicroRNAs from Dry Period and Peak Lactation Mammary Gland Tissues. PLoS ONE, 2012, 7(12): e52388. 42. Yang Zhou, Xianyong Lan, Yao Xu, Bao Zhang, Mijie Li, Yongzhen Huang, Jiajie Sun, Hanfang Cai, Chuzhao Lei, and Hong Chen. Exploring polymorphisms and potential application roles of the bovine Nfix gene in breeding. Genome, 2012, 55: 845-851. 43. Ya Zhang，Jinlong Zhu，Chen Wang，Jiajie Sun，Xinsheng Lai，Yao Xu，Xianyong Lan，Chuzhao Lei，Chunlei Zhang，Dongying Yang，and Hong Chen. Exploring polymorphisms of the bovine RARRES2 gene and their associations with growth traits. Mol Biol Rep, 2012, 39:2305-2311. 44. Zhuanjian Li，Xianyong Lan，Jiajie Sun，Jing Wang，YongZheng Huang，Wenjiao Guo, Bao Zhang, Chuzhao Lei, Chunlei Zhang, Hong Chen. Molecular characterization and haplotype combination of PrRP gene polymorphism and its association with production traits in Chinese native goats. Small Ruminant Research，2012, 105(1-3): 69-78. 45. Xingtang Fang，Jingmin Zhang，Haixia Xu，Chunlei Zhang，Yu Du，Xiuying Shi，Danxia Chen，Jiajie Sun，Qijiang Jin，Xianyong Lan，and Hong Chen. Polymorphisms of diacylglycerol acyltransferase 2 gene and their relationship with growth traits in goats. Molecular Biology Reports, 2012, 39(2): 1801-1807. 46. Yongzhen Huang, Hua He, Jiajie Sun, Jing Wang, Zhuanjian Li, Xianyong Lan, Chuzhao Lei，Chunlei Zhang，Enping Zhang，Juqiang Wang and Hong Chen. Haplotype combination of SREBP-1c gene sequence variants is associated with growth traits in cattle. Genome, 2011, 54: 507-516. 47. Qijiang Jin, Jiajie Sun, Xingtang Fang, Chunlei Zhang, Liu Yang, Danxia Chen, Xiuying Shi, Yu Du, Xianyong Lan and Hong Chen. Molecular characterization and polymorphisms of the caprine Somatostatin (SST) and SST Receptor 1 (SSTR1) genes that are linked with growth traits. Molecular Biology Reports，2011, 38(5): 3129-3135. 48. Xingtang Fang, Yu Du, Chunlei Zhang, Xiuying Shi, Danxia Chen, Jiajie Sun, Qijiang Jin, Xianyong Lan, Hong Chen. Polymorphism in a Microsatellite of the Acrp30 Gene and Its Association with Growth Traits in Goats. Biochemical Genetics, 2011, 49(7-8): 533-539. 49. Shan Liming, Jiajie Sun, Zhang Chunlei, Fang Xingtang, Lei Chuzhao, Lan Xianyong, and Chen Hong. The polymorphisms of bovine PCSK1 gene and their associations with growth traits. Genes & Genomics, 2011, 33(1): 57-63. 50. Qijiang Jin, Xingtang Fang, Chunlei Zhang, Liu Yang, Jiajie Sun Danxia Chen, Xiuying Shi, Yu Du, Xianyong Lan，Hong Chen. A novel SNP of the GHRL gene in goat and its association with growth traits. Small Ruminant Research, 2010, 90：150-152. 51. Qijiang Jin, Xing Tang Fang, Liu Yang, Chun Lei Zhang, Jiajie Sun, Dan Xia Chen, X. Y. Shi, Yu Du, Chuchao Lei and Hong Chen. Novel SNPs of the Caprine Growth Hormone Secretagogue Receptor （GHSR） Gene and Their Association with Growth Traits in Goats. Biochemical Genetics, 2010, 48 (9-10): 847-856. 52. Danxia Chen, Qijiang Jin, Xingtang Fang，Chunlei Zhang, Jiajie Sun, Xiuying Shi, Yu Du, Xianyong Lan, and Hong Chen. Analysis of the polymorphisms in the caprine PRDM16, SHH and SF-1 genes and their association with production traits in goats. Small Ruminant Research, 2010, 93: 193-197.