个人简介
教育经历
9/2016—7/2020 中国农业大学，食品科学与营养工程学院，农产品加工及贮藏工程专业，博士
9/2014—7/2016 中国农业大学，食品科学与营养工程学院，农产品加工及贮藏工程专业，硕士
9/2010—7/2014 四川农业大学，食品学院，食品质量与安全专业，学士
工作经历 3/2021-至今：河南农业大学食品科学技术学院
科研项目
1. 食物致敏原及膳食成分对肠道特征微生物的影响机制研究（Grant No.2019YFC1605003），国家重点研发计划，参与
2. 基于不同加工处理研究乳脂肪球膜稳定性及其对肠道菌群的调节作用与机制（Grant No. 31871806），国家自然科学基金，参与
学术交流
经历 第四届食品科学与人类健康国际研讨会、第二届食品营养与健康国际研讨会、第三届国际脂质科学与健康研讨会、第九届食品科学国际年会、第三届食品科学与人类健康国际研讨会、第八届中国乳业科技大会等
研究领域
食源功能活性因子的开发与应用；功能因子改善代谢综合征的分子营养机制
近期论文
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1. Tiange Li, Han Gong, Qichen Yuan, Min Du, Fazheng Ren and Xueying Mao. Supplementation of polar lipids-enriched milk fat globule membrane in high-fat diet-fed rats during pregnancy and lactation promotes brown/beige adipocyte development and prevents obesity in male offspring. FASEB Journal, 2020, 34(3): 4619-4634.
2. Tiange Li, Min Du, Hanning Wang and Xueying Mao. Milk fat globule membrane and its component phosphatidylcholine induce adipose browning both in vivo and in vitro. Journal of Nutritional Biochemistry, 2020, 81: 108372.
3. Tiange Li, Rui Chang, Huijuan Zhang, Min Du and Xueying Mao. Water extract of Potentilla discolor Bunge improved hepatic glucose homeostasis by regulating gluconeogenesis and glycogen synthesis in high-fat diet and streptozotocin-induced type diabetic mice. Frontiers in Nutrition, 2020, 7: 161.
4. Tiange Li, Jing Gao, Min Du and Xueying Mao. Bovine α-lactalbumin hydrolysates ameliorate obesity-associated endotoxemia and inflammation in high-fat diet-fed mice through modulation of gut microbiota. Food & Function, 2019, 10 (6): 3368-3378.
5. Tiange Li, Jing Gao, Min Du, Jiajia Song and Xueying Mao. Milk fat globule membrane attenuates high-fat diet-induced obesity by inhibiting adipogenesis and increasing uncoupling protein 1 expression in white adipose tissue of mice. Nutrients, 2018, 10(3): 331.
6. Tiange Li, Dongxiao Gao, Min Du, Xue Cheng and Xueying Mao. Casein glycomacropeptide hydrolysates inhibit PGE2 production and COX2 expression in LPS-stimulated RAW 264.7 macrophage cells via Akt mediated NF-κB and MAPK pathways. Food & Function, 2018, 9(4): 2524-2532.
7. Tiange Li, Jing Gao, Min Du and Xueying Mao. Milk fat globule membrane supplementation modulates the gut microbiota and attenuates metabolic endotoxemia in high-fat diet-fed mice. Journal of Functional Foods, 2018, 47: 56-65.
8. Tiange Li, Bin Chen, Min Du, Jiajia Song, Xue Cheng, Xu Wang and Xueying Mao. Casein glycomacropeptide hydrolysates exert cytoprotective effect against cellular oxidative stress by up-regulating HO-1 expression in HepG2 cells. Nutrients, 2017, 9(31), 1-15.
9. Tiange Li, Xue Cheng, Min Du, Bin Chen and Xueying Mao. Upregulation of heme oxygenase-1 mediates the anti-inflammatory activity of casein glycomacropeptide (GMP) hydrolysates in LPS-stimulated macrophages. Food & Function, 2017, 8(7), 2475-2484.
10. Lihua Han, Tiange Li, Min D, Rui Chang, Biyuan Zhan and Xueying Mao. Beneficial effects of potentilla discolor bunge water extract on inflammatory cytokines release and gut microbiota in high-fat diet and streptozotocin-induced Type 2 diabetic mice. Nutrients, 2019, 11: 670.
11. Jiajia Song, Tiange Li, Xue Cheng, Xiaomin Ji, Dongxiao Gao, Min Du, Naiyi Jiang, Xueling Liu and Xueying Mao. Sea cucumber peptides exert anti-inflammatory activity through suppressing NF-κB and MAPK and inducing HO-1 in RAW264.7 macrophages. Food & Function, 2016, 7, 2773-2779.
12. Han Gong, Qichen Yuan, Jinzhu Pang, Tiange Li, Jufang Li, Biyuan Zhan, Rui Chang and Xueying Mao. Dietary milk fat globule membrane restores decreased intestinal mucosal barrier development and alterations of intestinal flora in infant formula-fed rat pups. Molecular Nutrition & Food Research, 2020, 64: 2000232.
13. Qichen Yuan, Biyuan Zhan, Min Du, Rui Chang, Tiange Li and Xueying Mao. Dietary milk fat globule membrane regulates JNK and PI3K/Akt pathway and ameliorates type 2 diabetes in mice induced by a high-fat diet and streptozotocin. Journal of Functional Foods, 2019, 60: 103435.
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