耿晋 - 中国科学院深圳先进技术研究院 -

个人简介

After gaining PhD in Chemistry with Professor Dave M. Haddleton from University of Warwick, United Kingdom. He moved to University of Cambridge as Postdoctoral Research Fellow with Isaacs Newton Funding, he continued with postdoctoral with Professor Oren A. Scherman in Melville Laboratory of University of Cambridge before he gained a position at GKN as Research Scientist (2011-2014). He then move to take a senior research fellow position at University of Edinburgh. In 2018, he is moving to Shenzhen CAS where he took up his current position as Director/Professor in the Centre for Polymers in Medicine.

研究领域

Polymer Chemistry Drug Development Cancer Diagnosis Nanotechnology

近期论文

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Lysosome Targeting Chimaeras for Glut1-Facilitated Targeted Protein Degradation. Jinyan Luo, Quan Gaoa, Kui Tan, Shiling Zhang, Weiwei Shi, Lei Luo, Zhiying Li, Ghada E. Khedr, Jie Chen, Youwei Xu, Ming Luo, Qi Xing, and Jin Geng*. J. Am. Chem. Soc. 2024. Protocol to synthesize sequence-controlled glycooligomers for tumour targeting. Q. Lin, J. Chen, Y. Zhang, Q. Gao, L. Zhu, Q. Xing* Jin Geng*. Star Protocols. 2024 Amphiphilic Block Copolymers Containing Benzenesulfonyl Azide Groups as Visible Light-Responsive Drug Carriers for Image-Guided Delivery Lei Luo, Fei Liu, Zhiying Li, Siyuan Yue, Liang Wang, Shiling Zhang, Shanmeng Lin, Jinyan Luo, Meng Wang, Yichuan Zhang, Mohamed Abdelrahim, Qi Xing*, and Jin Geng* Biomacromolecules 2024. Thermal and Oxidation Dual-Responsive Random Copolymer Self-Assembly of Nanostructure. Lan Lou, Shiling Zhang, Al-Hassan S. Mahdy, Meng Wang, Kai Li,*, Qi Xing,*, Jin Geng*, Polymer Chemistry, 2024. Visible Light-Promoted C(sp3)-C(sp3) Cross-Coupling of Amino Acids and Aryl Trifluoromethyl Ketones Through Simultaneous Decarboxylation and Defluorination Kui Tan, Jiaan He, Zhilin Mu, Ibrahim M. Ammar, Chao Che,* Jin Geng* and Qi Xing*, Organic Letters, 2023. Investigating AIE Behaviors of Amphiphilic AIEgen-based Polymers through Self-Assembly Architectures and Hydrophobic Core Arrangements. L. Wang, G. E. Khedr, L. Luo, S. Zhang, Z. Li, S. Lin, J. Luo, Qi Xing,* and Jin Geng*. Polymer Chemistry, 2023, 14(21), 4515. Ultrasound-Responsive Glycopolymer Micelles for Targeted Dual Drug Delivery in Cancer Therapy S. Lin, L. Zhu, Z. Li, S. Yue, Z. Wang, Y. Xu, Y. Zhang, Q. Gao, J. Chen, T. Yin, L. Niu, Jin Geng*. Biomater. Sci., 2023, 11, 6149-6159 Tumor-Targeting Polymer–Drug Conjugate for Liver Cancer Treatment In Vitro. J. Xu, S. Lin, H. Hu*, Q. Xing*, and Jin Geng*. Polymers, 2022, 14(21), 4515. Oxidative Degradation of Thermosets Based on Thioketal Cleavable Linkages in Aqueous Environment, Mohamed Abdelrahim, Jun Zhang, Quan Gao, Wael A. Zordok, Ji Liu*, Jin Geng*. ACS Appl. Polym. Mater. 2022, 4, 10, 7812–7822. A Nanomedicine Enables Synergistic Chemo/Photodynamic Therapy for Pancreatic Cancer Treatment, Liwei Zhu, Shanmeng Lin, Wenqiang Cui, Youwei Xu, Liang Wang, Zhaohan Wang, Shuguang Yuan, Yichuan Zhang*, Yingfang Fan* and Jin Geng*. Biomater. Sci., 2022,10, 3624-3636 Aggregation-Induced Emission Luminogen Catalyzed Photocontrolled Reversible Addition–Fragmentation Chain Transfer Polymerization in an Aqueous Environment. Zhiying Li, Qianjin Lian, Youwei Xu, Yichuan Zhang, Pengfei Zhang, and Jin Geng*. Macromolecules 2022, 55, 7, 2904–2910. Controlled Intracellular Polymerization for Cancer Treatment. Yichuan Zhang, Quan Gao, Weishuo Li, Rongkun He, Liwei Zhu, Qianjin Lian, Wang, Liang; Yang Li,; Mark Bradley, Jin Geng*. JACS Au 2022, 2, 3, 579–589. Supramolecular Self-assembly in Living Cells. Mohamed Dergham,Shanmeng Lin,Jin Geng* Angewandte Chemie. 2022, 61. 16. Harnessing Focal Adhesions to Accelerate p53 Accumulation and Anoikis of A549 Cells Using Colloidal Self-Assembled Patterns (cSAPs) Myagmartsend Enkhbat, Boya Zhong, Ray Chang, Jin Geng, Long-Sheng Lu, Yin-Ju Chen, and Peng-Yuan Wang* ACS Appl. Bio Mater. 2022, 5, 1, 322–333. Switching-on Prodrugs using Radiotherapy. Jin Geng*, Yichuan Zhang, Kevin Neumann, Hua Dong, Hamish Porter, Mark Potter, David Argyle, Mark Bradley*. Nature Chemistry, 2021. C=C Bond Oxidative Cleavage of BODIPY Photocages by Visible Light. Youwei Xu, Shanmeng Lin, Rongkun He, Yichuan Zhang, Quan Gao, Dennis Ng, Jin Geng*. Chemistry – A European Journal. 2021. Light-controlled, living radical polymerisation mediated by fluorophore-conjugated RAFT agents. S Zhang, Y Zhang, M Üçüncü, A Lilienkampf, J Geng*, Mark Bradley*. Polymer, 2021, 226, 123840. Bioorthogonal Swarming: in situ Generation of Dendrimers. Y Zhang, M Üçüncü, A Gambardella, A Baibek, Jin Geng, S Zhang, J Clavadetscher, I Litzen, M Bradley* and A Lilienkampf. J. Am. Chem. Soc., 2020, 142, 52, 21615–21621. BODIPY Based Realtime, Reversible and Targeted Fluorescent Probes for Biothiols Imaging in Living Cells. R He, Y Zhang, S Madhu, Q Gao, Q Lian, SS Raghavan, Jin Geng*. Chem. Commun., 2020,56, 14717-14720 Multifunctional, histidine-tagged polymers: antibody conjugation and signal amplification. Y Zhang, A Gambardella, M Üçüncü, Jin Geng, J Clavadetscher, M Bradley*, Chem. Commun., 2020, 56, 13856-13859 Photo-controlled one-pot strategy for the synthesis of asymmetric three-arm star polymers Yichuan Zhang, Mark Bradley, Jin Geng*. Polymer Chemistry. 2019, 10, 4769-4773. Radical Polymerisation inside Living Cells. Jin Geng, W. Li, Y. Zhang, N. Thottappillil, J. Clavadetscher, M. Bradley. Nature Chemistry. 2019. 11, 578 - 586.