个人简介

Dr. Ashok Mulchandani obtained his B. Tech. in Chemical Engineering from Laxminarayan Institute of Technology, Nagpurin 1976 and M. Tech. in Chemical Engineering from Indian Institute of Technology, Powai in 1978. After working at Vulcan-Laval, Pune from 1978 to 1980, he joined McGill University, Montreal, Canada for Ph.D. and graduated in 1985. From 1985 to 1987 he worked as a Postdoctoral Fellow in the Chemical Engineering Department at Laval University, Canada and from 1987 to 1990 as a Research Associate at the Biotechnology Research Institute at Montreal, Canada. In 1990 he joined the University of Western Ontario, London, Canada and then moved to the University of California, Riverside in 1991 as the founding faculty of the Department of Chemical Engineering and pioneer faculty of Bourns College of Engineering. From 2000 to 2004 he was the Chair of the Department of Chemical and Environmental Engineering. From 2003 to 2015 Prof. Mulchandani was the Editor-in-Chief of the Applied Biochemistry and Biotechnology. He is presently an Associate Editor of Frontiers in Chemistry and member of editorial boards of several journals. He has received several honors and awards including Research Initiation Award from the national Science Foundation and Faculty Participation Award from the Department of Energy. He has delivered several Plenary and Keynote lectures at National and International conferences and Gordon Conference. Prof. Mulchandani’s research efforts are primarily aimed at developing innovative technologies for improving human health and the quality of life. One may summarize his work by "Better Science, Better Health, Better Life." He applies the tools of biotechnology and nanotechnology for the creation of novel and very effective (bio)analytical devices, (bio)remediation techniques and (bio)energy generation technologies to help enhance the quality of life. In biosensors, a field in which he is recognized nationally and internationally as a leader, he works on development of very effective (bio)sensors for fast, highly sensitive, selective and point-of-use/care detection of biomarkers for the early detection of debilitating diseases such as cancer, psycho-social stress, myocardial infarction, etc.; assessment of personal/individual exposure to toxic industrial chemicals for health care and security; monitoring of viruses, toxins, and bacteria for healthcare and water and food safety; and explosives, bio-warfare and chemical warfare agents for homeland security. Aside from biosensors, he is also recognized for his world class research program in development of “green engineering” techniques for heavy metal removal from water and soil, and the degradation of chemical warfare agents, pesticides and recalcitrant chemicals and highly efficient and low cost methods for separation and purification of biomolecules such as antibodies, enzymes, nucleic acids etc., for therapeutics. These research activities have received ~ $16 million grants over the past twenty years from intensively competitive programs of NIH, NSF, USDA, EPA, DARPA and Department of Justice. Prof. Mulchandani has published more than 270 peer-reviewed articles in peer-reviewed premier journals, 13 book chapters, a dozen conference proceedings articles and over 260 conference abstracts. He has co-edited four textbooks that include very popular Enzyme and Microbial Biosensors: Protocols and Techniques and Affinity Biosensors: Protocol and Techniques. Prof. Mulchandani has mentored 30 Ph.D., 10 M.S., 40 Postdoctoral Fellows, 21 international visiting researchers and a large number of undergraduate researchers. His students/postdocs/visiting researchers are working in academia, industry and government laboratories. Ashok Mulchdani's research interests include nanobiotechnology, environmental biotechnology, biosensors and bioengineering.

研究领域

Analytical Chemistry

Biotechnology and Biomolecular Engineering

近期论文

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K. K. Krishnani, W. Chen, A. Mulchandani, "Bactericidal activity of elastin-like polypeptide biopolymer with polyhistidine domains and silver," Colloids and Surfaces B: Biointerfaces, ACCEPTED, 3/10/14. L. N. Cella, P. Biswas, M. V. Yates, A. Mulchandani, W. Chen, "Quantitative assessment of in vivo HIV protease activity using genetically engineered QD-based FRET probes," Biotechnology Bioengineering, 6 p, ACCEPTED, 01/21/14. S. Badhulika, C. Tlili, A. Mulchandani, "Poly (3-aminophenyl boronic acid) functionalized carbon nanotubes based chemiresistive sensors for detection of sugars," Analyst, 5 p, ACCEPTED 2/18/14. S. Badhulika, N. V. Myung, A. Mulchandani, "Conducting polymer coated single-walled carbon nanotube gas sensors for detection of volatile organic compounds," Talanta, 123, 109-114, 2014. Rajesh, V. Sharma, N. K. Puri, R. K. Singh, A. M. Biradar, A. Mulchandani, "Label-free detection of cardiac troponin-I using gold nanoparticels functionalized sigle-walled carbon nanotubes based chemiresistive biosensor," Applied Physics Letters, 103, Art. 203703, 4 p, 2013. S. Srinives, T. Sarkar, A. Mulchandani, "Primary amine-functionalized polyaniline nanothin film sensor for detecting formaldehyde," Sensors & Actuators B-Chemical, 194, 255-259, 2014. T. Sarkar, S. Sriniver, S. Sarkar, R. C. Haddon, A. Mulchandani, "Single-walled carbon nanotube-poly(porphyrin) hybrid for volatile organic compounds," J. Physical Chemistry C, 118, 1602-1610, 2014. K. Datta, P. Ghosh, A. Mulchandani, S. H. Han, P. Koinkar, M. D. Shirsat, "Organic field-effect transistors: predictive control on performance parameters," Journal of Physics D: Applied Physics, 46, Art. 495110, 7 p, 2013. P. Ramnani, Y. N. Gao, M. Ozsoz, A. Mulchandani, "Electronic detection of microRNA at attomolar level with high selectivity," ANALYTICAL CHEMISTRY, 85, 8061-8064, 2013. P. Ghosh, K. Datta, A. Mulchandani, S. H. Han, P. Koinkar, M. D. Shirsat, "Poly(o-toluidine) Nanowires Based Organic Field Effect Transistors: A Study on Influence of Anionic Size of Dopants and SWNTs as a Dopant," JOURNAL OF PHYSICAL CHEMISTRY C, 117, 15414-15420, 2013. T. Sarkar, Y. N. Gao, A. Mulchandani, "Carbon Nanotubes-Based Label-Free Affinity Sensors for Environmental Monitoring," APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 170, 1011-1025, 2013. S. Srinives, T. Sarkar, A. Mulchandani, "Nanothin Polyaniline Film for Highly Sensitive Chemiresistive Gas Sensing," ELECTROANALYSIS, 25, 1439-1445, 2013. K. K. Krishnani, S. Srinives, B. C. Mohapatra, V. M. Boddu, J. M. Hao, X. Meng, A. Mulchandani, "Hexavalent chromium removal mechanism using conducting polymers," JOURNAL OF HAZARDOUS MATERIALS, 252, 99-106, 2013. A. Rushi, K. Datta, P. Ghosh, A. Mulchandani, M. D. Shirsat, "Iron tetraphenyl porphyrin functionalized single wall carbon nanotubes for the detection of benzene," MATERIALS LETTERS, 96, 38-41, 2013. X. Y. Cao, C. Yang, R. H. Liu, Q. Li, W. Zhang, J. L. Liu, C. J. Song, Q. L. Qiao, A. Mulchandani, "Simultaneous degradation of organophosphate and organochlorine pesticides by Sphingobium japonicum UT26 with surface-displayed organophosphorus hydrolase," BIODEGRADATION, 24, 295-303, 2013. S. Mubeen, M. Lai, T. Zhang, J. H. Lim, A. Mulchandani, M. A. Deshusses, N. V. Myung, "Hybrid tin oxide-SWNT nanostructures based gas sensor," ELECTROCHIMICA ACTA, 92, 484-490, 2013. P. Ghosh, K. Datta, A. Mulchandani, R. G. Sonkawade, K. Asokan, M. D. Shirsat, "A chemiresistive sensor based on conducting polymer/SWNT composite nanofibrillar matrix-effect of 100 MeV O-16 ion irradiation on gas sensing properties," SMART MATERIALS AND STRUCTURES, 22, Art # 035004, 2013. M. Sebaa, T. Y. Nguyen, R. K. Paul, A. Mulchandani, H. N. Liu, "Graphene and carbon nanotube-graphene hybrid nanomaterials for human embryonic stem cell culture," MATERIALS LETTERS, 92, 122-125, 2013. Rajesh, R. k. Paul, A. Mulchandani, "Platinum nanoflowers decorated three-dimensional graphene-carbon nanotubes hybrid with enhanced electrocatalytic activity," JOURNAL OF POWER SOURCES, 223, 23-29, 2013. J. L. Gong, T. Sarkar, S. Badhulika, A. Mulchandani, "Label-free chemiresistive biosensor for mercury (II) based on single-walled carbon nanotubes and structure-switching DNA," APPLIED PHYSICS LETTERS, 102, Art #013701, 2013.