研究领域
Dr Walduck’s research focuses on understanding the inflammation and pathogenesis caused by significant human and animal pathogens. Her group chiefly employs bacterial pathogens Helicobacter pylori and Staphylococcus aureus as model organisms to address questions on the interaction between host and pathogen in chronic and acute infection.
Examples of research projects addressed by her group include:
Understanding the mechanisms underlying vaccine-induced protection against H. pylori
Mechanisms of altered gastric barrier function in H. pylori infection
Aspirin as an adjunct therapy for severe sepsis
近期论文
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Bertrand, P.,Polglaze, K.,Chen, H.,Sandow, S.,Walduck, A.,Jenkins, T.,Lomax, A.,Liu, L. (2016). Excitability and synaptic transmission in the enteric nervous system: Does diet play a role? In: The Enteric Nervous System: 30 Years Later, Springer, Adelaide, Australia
Walduck, A.,Andersen, L.,Raghavan, S. (2015). Inflammation, immunity, and vaccines for Helicobacter pylori Infection In: Helicobacter, 20, 17 - 25
Sjökvist Ottsjö, L.,Flach, C.,Nilsson, S.,de W Malefyt, R.,Walduck, A.,Raghavan, S. (2015). Defining the roles of IFN-gamma and IL-17A in inflammation and protection against Helicobacter pylori infection In: PLoS ONE, 10, 1 - 20
Judd, L.,Chalinor, H.,Walduck, A.,Pavlic, D.,Däbritz, J.,Dubeykovskaya, Z.,Wang, T.,Menheniott, T.,Giraud, A. (2014). TFF2 deficiency exacerbates weight loss and alters immune cell and cytokine profiles in DSS colitis, and this cannot be rescued by wild-type bone marrow In: American Journal of Physiology - Gastrointestinal and Liver Physiology, 308, G12 - G24
Gorrell, R.,Wijburg, O.,Pedersen, J.,Walduck, A.,Kwok, T.,Strugnell, R.,Robins-Browne, R. (2013). Contribution of secretory antibodies to intestinal mucosal immunity against helicobacter pylori In: Infection and Immunity, 81, 3880 - 3893
Kalinna, B.,Walduck, A. (2013). Subversion of immunity by schistosomes In: Microbiology Australia, , 137 - 141
Rivera, J.,Walduck, A.,Thomas, S.,Glaros, E.,Hooker, E.,Guida, E.,Sobey, C.,Dummond, G. (2013). Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP In: Naunyn-Schmiedeberg's Archives of Pharmacology, 386, 1081 - 1093
Rivera, J.,Walduck, A.,Strugnell, R.,Sobey, C.,Dummond, G. (2012). Chlamydia pneumoniae induces a pro-inflammatory phenotype in murine vascular smooth muscle cells independently of elevating reactive oxygen species In: Clinical and Experimental Pharmacology and Physiology, 39, 218 - 226
Hodgson, K.,Govan, B.,Walduck, A.,Ketheesan, N.,Morris, J. (2012). Impaired early cytokine responses at the site of infection in a murine model of type 2 diabetes and melioidosis comorbidity In: Infection and Immunity, Online, 1 - 29
Walduck, A.,Becher, D. (2012). Leptin, CD4+ Treg and the prospects for vaccination against H. Pylori infection In: Frontiers in Immunology, 3, 1 - 8