研究领域
Computational modelling and simulations of biomolecular systems, with special focus on:
Biological membranes
Protein-lipid interactions
Protein misfolding, abnormal aggregation and subsequent amyloid fibril formation
Protein-surface interactions in nanobiotechnology
近期论文
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Hung, A. (2016). Effects of interfaces on aggregates of peptides derived from pancreatic islet amyloid polypeptide In: Molecular Simulation, 42, 580 - 595
Kompella, S.,Hung, A.,Clark, R.,Mari, F.,Adams, D. (2015). Alanine Scan of alpha-Conotoxin RegIIA Reveals a Selective alpha 3 beta 4 Nicotinic Acetylcholine Receptor Antagonist In: Journal of Biological Chemistry, 290, 1039 - 1048
Tortorella, S.,Hung, A.,Karagiannis, T. (2015). The implication of cancer progenitor cells and the role of epigenetics in the development of novel therapeutic strategies for chronic myeloid leukemia In: Antioxidants and Redox Signaling, 22, 1425 - 1462
Kompella, S.,Cuny, H.,Hung, A.,Adams, D. (2015). Molecular basis for differential sensitivity of alpha-conotoxin RegIIA at rat and human neuronal nicotinic acetylcholine receptors In: Molecular pharmacology, 88, 993 - 1001
Chhabra, S.,Belgi, A.,Bartels, P.,van Lierop, B.,Robinson, S.,Kompella, S.,Hung, A.,Callaghan, B.,Adams, D.,Robinson, A.,Norton, R. (2014). Dicarba analogues of alpha-conotoxin RgIA. structure, stability, and activity at potential pain targets In: Journal of Medicinal Chemistry, 57, 9933 - 9944
van Lierop, B.,Robinson, S.,KOMPELLA, S.,Belgi, A.,McArthur, J.,Hung, A.,MacRaild, C.,Adams, D.,Norton, R.,Robinson, A. (2013). Dicarba a-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors In: ACS Chemical Biology, 8, 1815 - 1821
Grishin, A.,Cuny, H.,Hung, A.,Clark, R.,Brust, A.,Akondi, K.,Alewood, P.,Craik, J.,Adams, D. (2013). Identifying key amino acid residues that affect a-conotoxin AuIB inhibition of a3ß4 nicotinic acetylcholine receptors In: Journal of Biological Chemistry, 288, 34428 - 34442
Hung, A.,Mager, M.,Hembury, M.,Stellacci, F.,Stevens, M.,Yarovsky, I. (2013). Amphiphilic amino acids: A key to adsorbing proteins to nanopatterned surfaces? In: Chemical Science, 4, 928 - 937
Todorova, N.,Yeung, L.,Hung, A.,Yarovsky, I. (2013). "Janus" cyclic peptides: A new approach to amyloid fibril inhibition? In: PloS One, 8, 1 - 8
Russo, S.,Hung, A. (2012). Thermodynamic modelling of FeS2 In: Nature's Nanostructures, Taylor and Francis, United States