Greening, Chris - Monash University - School of Biological Sciences

研究领域

Chris’ research is centred on two main themes. His environmental research is exploring the physiological and ecological significance of microbial metabolism of reduced gases, i.e. hydrogen, methane, and carbon monoxide. This research has shown that soil bacteria can enhance their long-term survival by scavenging trace gases from the atmosphere. He is exploring the significance of trace gas scavenging and other hydrogen-dependent processes in relation to microbial community structure and greenhouse gas cycling. His medical research is centred on identifying new drug targets for the treatment of tuberculosis, which continues to cause 1.5 million deaths per year. Through this research, he has shown that multiple hypothetical proteins upregulated by mycobacteria during stress-inducing conditions are critical for maintaining redox and ion homeostasis.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Carere CR, Hards K, Houghton KM, Power JF, McDonald B, Collet C, Gapes DJ, Sparling R, Cook GM, Greening C*, Stott MB* (2016) Aerobic H2 respiration enhances metabolic flexibility of methanotrophic bacteria. Manuscript submitted, preprint available on bioRxiv Jirapanjawat T & Ney B, Taylor MC, Warden AC, Afroze S, Russell RJ, Lee BM, Jackson CJ, Oakeshott JG, Pandey G, Greening C* (2016) The redox cofactor F420 protects mycobacteria from diverse antimicrobial compounds and mediates a reductive detoxification system. Applied and Environmental Microbiology, doi: 10.1128/AEM.02500-16 [IF = 3.7, CITES = 0] Søndergaard D*, Pedersen CNS, Greening C* (2016) HydDB: a web tool for hydrogenase classification and analysis. In press, Scientific Reports [IF = 5.2, CITES = 0] Ney B & Ahmed HF, Carere CR, Biswas A, Oakeshott JG, Morales SE, Watt SJ, Warden A, Taylor MC, Stott MB, Jackson CJ*, Greening C* (2016). The methanogenic redox cofactor F420 is widely synthesized by aerobic soil bacteria. The ISME Journal, doi: 10.1038/ismej.2016.100 [IF = 9.3, CITES = 2] Cook GM*, Hards K, Dunn E, Heikal A, Nakatani Y, Greening C, Crick DC, Fontes FL, Pethe K, Berney M (2016). OXPHOS as a target space for tuberculosis: success, caution, and future directions. In Tuberculosis and the Tubercle Bacilli (edited by Jacobs Jr WR), ASM Press, Washington DC [IF = N/A, CITES = 0] Wolf PC, Biswas A, Morales SE, Greening C*, Gaskins HR* (2016). H2 metabolism is diverse and widespread among human colonic microbes. Gut Microbes 7, 235-245. [IF = TBA, CITES = 1] Greening C*, Maier RJ (2016). Atmospheric H2 fuels plant-microbe interactions. Environmental Microbiology 18, 2289-2291 [IF = 5.9, CITES = 0]