Dowling, Damian - Monash University - School of Biological Sciences

研究领域

Research in Damian Dowling’s group is focused on understanding how life evolves. We draw on experimental evolutionary, genomic and ecological techniques to explore fundamental biological questions. Our core goal is to understand the evolution of our energy-producing genes. The mitochondria are salient to eukaryote life. Curiously, their functionality hinges on fine-tuned interactions between genes that reside over two obligate genomes. This sets the stage for inter-genomic evolutionary collaborations and conflicts between these genes, which will ultimately affect the dynamics of core life history processes

近期论文

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Mitonuclear interactions, mtDNAmediated thermal plasticity, and implications for the Trojan Female Technique for pest control JN Wolff, DM Tompkins, NJ Gemmell, DK Dowling Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies JN Wolff, N Pichaud, MF Camus, G Côté, PU Blier, DK Dowling Complete mitochondrial genome sequences of thirteen globally sourced strains of fruit fly (Drosophila melanogaster) form a powerful model for mitochondrial research Jonci N. Wolff, M. Florencia Camus, David J. Clancy, and Damian K. Dowling Intergenomic interactions between mitochondrial and Y-linked genes shape male mating patterns and fertility in Drosophila melanogaster Winston K.W. Yee, Bjorn Rogell, Bernardo Lemos and Damian K. Dowling Single Nucleotides in the mtDNA Sequence Modify Mitochondrial Molecular Function and Are Associated with Sex-Specific Effects on Fertility and Aging M. Florencia Camus, Jochen B.W. Wolf, Edward H. Morrow, Damian K. Dowling