研究领域
Jeremy’s research group studies bacteriophage and investigates their role and function in the human body. Projects in his research group include the bacteriophage adherence to mucus (BAM) model; utilizing microfluidic devices to create life-like mucosal surfaces; investigating the dynamics of bacteriophage diffusion in complex media and fluids; bioengineering bacteriophages and nanoparticles for prospective biotechnology applications.
近期论文
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Natasha Bonilla, Maria Isabel Rojas, Giuliano Netto Flores Cruz, Shr-Hau Hung, Forest Rohwer, Jeremy J. Barr. Phage on tap–a quick and efficient protocol for the preparation of bacteriophage laboratory stocks PeerJ 2016;
Barr JJ, Dutilh BE, Skennerton CT, Fukushima T, Hastie ML, Gorman JJ, Tyson GW, Bond PL. Metagenomic and metaproteomic analyses of Accumulibacter phosphatis-enriched floccular and granular biofilm. Environ. Microbiol. 2016; 18(1):273-87
Barr JJ, Auro R, Sam-Soon N, Kassegne S, Peters G, Bonilla N, Hatay M, Mourtada S, Bailey B, Youle M, Felts B, Baljon A, Nulton J, Salamon P, Rohwer F. Subdiffusive motion of bacteriophage in mucosal surfaces increases the frequency of bacterial encounters. Proc. Natl. Acad. Sci. U.S.A. 2015; 112(44):13675-80
Skennerton CT, Barr JJ, Slater FR, Bond PL, Tyson GW. Expanding our view of genomic diversity in Candidatus Accumulibacter clades. Environ. Microbiol. 2015; 17(5):1574-85
Tariq MA, Everest FL, Cowley LA, De Soyza A, Holt GS, Bridge SH, Perry A, Perry JD, Bourke SJ, Cummings SP, Lanyon CV, Barr JJ, Smith DL. A metagenomic approach to characterize temperate bacteriophage populations from Cystic Fibrosis and non-Cystic Fibrosis bronchiectasis patients. Front Microbiol 2015; 6:97
Dutilh BE, Cassman N, McNair K, Sanchez SE, Silva GG, Boling L, Barr JJ, Speth DR, Seguritan V, Aziz RK, Felts B, Dinsdale EA, Mokili JL, Edwards RA. A highly abundant bacteriophage discovered in the unknown sequences of human faecal metagenomes. Nat Commun 2014; 5:4498
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