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研究领域

Suresh's research group (SKB Lab) focuses on two key areas. His group is interested in deciphering mechanisms through which plants sense and respond to changes in temperature. They use a combination of mutant analysis, natural variation and genomics to understand thermal responses in plants. The second area is related to understanding molecular mechanisms of genetic diseases.

近期论文

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Tabib, A., Vishwanathan, S., Seleznev, S., McKeown, P., Downing, T., Dent, C., Sanchez-Bermejo, E., Colling, L., Spillane, C and Balasubramanian, S (2016) A polynucleotide repeat expansion causing temperature-sensitivity persists in wild Irish accessions of Arabidopsis thaliana, Frontiers in Plant Science, 16 Aug 2016, doi: 10.3389/fpls.2016.01311 Sureshkumar, S., Dent, C., Seleznev, A., Tasset, C and Balasubramanian, S (2016) Nonsense-mediated mRNA decay modulates FLM-dependent thermosensory flowering response in Arabidopsis. Nature Plants, 29 Apr 2016, Article Number: 16055, doi: 10.1038/NPLANTS.2016.55 Essebier, A., Wolf, PV., Cao, MD., Carroll, BJ., Balasubramanian, S* and Boden, M (2016) Statistical enrichment of epigenetic states around triplet repeats that can undergo expansions. Frontiers in Neuroscience, 23 Feb 2016, doi:10.3389/fnins.2016.00092 (SB and MB are co-corresponding authors) Sanchez-Bermejo, E and Balasubramanian, S (2015) Natural variation involving deletion alleles of FRIGIDA modulate temperature-sensitive flowering responses in Arabidopsis thaliana. Plant Cell and Environment, 12 Dec 15, doi:10.1111/pce.12690. Raman, H., Raman, R., Coombes, N., Song, J., Pragnell, R., Banadaranayake, C., Tahira, R., Sundaramoorthi, V., Killian, A., Meng, J., Dennis, ES and Balasubramanian, S (2015) Genome-wide association analyses reveal complex genetic architecture underlying natural variation for flowering time in canola. Plant Cell and Environment, 1 Oct 15, doi:10.1111/pce.12644. Sanchez-Bermejo.E*., Zhu, W*., Tasset, C., Eimer, H., Sureshkumar, S., Singh, R., Sundaramoorthi, V., Colling, L and Balasubramanian, S (2015) Genetic architecture of natural variation in thermal responses of Arabidopsis. Plant Physiology, 169:647-659. (*equal contribution) Zhu, W*., Ausin, I*., Seleznev, A., Mendez-Vigo, B., Pico, FX., Sureshkumar, S. ,Sundaramoorthi, V., Bulach, D., Powell, D., Seemann, T., Alonso-Blanco, C and Balasubramanian, S (2015) Natural variation identifies ICARUS1, a universal gene required for cell proliferation and growth at high temperatures in Arabidopsis thaliana, PLoS Genetics, 11(5):e1005085 (* equal contribution and (S.B and CAB are co-corresponding authors) Cao, MD., Balasubramanian, S and Bodén, M (2014) Sequencing technologies and tools for short tandem repeat variation detection. Brief Bioinform. Feb 6, doi:10.1093/bib/bbu001. Cao, MD., Tasker, E., Willadsen, K., Imelfort, M., Vishwanathan, S., Sureshkumar, S., Balasubramanian, S* and Bodén, M* (2014) Inferring short tandem repeat variation from paired-end short reads. Nucleic Acids Res, 42(3):e16. (SB and MB are co-corresponding authors) Willadsen, K., Cao, MD., Wiles, J., Balasubramanian, S and Bodén, M (2013) Repeat-encoded poly-Q tracts show statistical commonalities across species. BMC Genomics, 14:76

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