研究领域

Systemic Lupus Erythematosus, glucocorticoids, Lupus, SLE, RA, GILZ , MIF, Rheumatoid Arthritis

Professor Morand's key interests are clinical outcome measurement ad biological profiling in SLE, and the actions of glucocorticoid induced proteins on the immune system. His group has pioneered the development of treat-to-target outcome measures in SLE, via the AsiaPacific Lupus Collaboration, which has over 1800 patients under study. Biomarker studies in SLE are also a major interest ,with 000s of samples linked to longitudinal clincial data archived in the Australian Lupus Registry & Biobank, headquartered at Monash. His lab group discovered the role in rheumatic disease of four glucocorticoid-regulated proteins. Most recently his group defined the role of GILZ in RA, Th17 pathways, B cell activation, and lupus, and are working on exploting its actions to develop a safe glucocortioid mimic

近期论文

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Association of low vitamin D with high disease activity in an Australian systemic lupus erythematosus cohort Yap, K. S. , Northcott, M. J. , Hoi, A. , Morand, E. F. & Nikpour, M. 2015 In : Lupus Science and Medicine. 2, 1, p. 1 - 7 7 p. Research - peer-review › Article Bcl-2 antagonists kill plasmacytoid dendritic cells from lupus-prone mice and dampen interferon-alpha production Zhan, Y. , Carrington, E. M. , Ko, H-J. , Vikstrom, I. B. , Oon, S. , Zhang, J-G. , Vremec, D. , Brady, J. L. , Bouillet, P. , Wu, L. , Huang, D. C. S. , Wicks, I. P. , Morand, E. F. , Strasser, A. & Lew, A. M. 2015 In : Arthritis & Rheumatology. 67, 3, p. 797 - 808 12 p. Research - peer-review › Article Characteristics of azathioprine use and cessation in a longitudinal lupus cohort Croyle, L. , Hoi, A. & Morand, E. F. 2015 In : Lupus Science and Medicine. 2, p. 1 - 7 7 p. Research - peer-review › Article Disseminated Enteroviral Infection Associated with Obinutuzumab Dendle, C. , Gilbertson, M. , Korman, T. , Golder, V. , Morand, E. F. & Opat, S. 2015 In : Emerging Infectious Diseases. 21, 9, p. 1661 - 1663 3 p. Other › Article GILZ regulates Th17 responses and restrains IL-17-mediated skin inflammation Jones, S. , Perera, D. N. , Fan, H. , Russ, B. E. , Harris, J. & Morand, E. F. 2015 In : Journal of Autoimmunity. 61, p. 73 - 80 8 p. Research - peer-review › Article Glucocorticoid-induced leucine zipper governs the therapeutic potential of mesenchymal stem cells by inducing a switch from pathogenic to regulatory Th17 cells in a mouse model of collagen-induced arthritis Luz-Crawford, P. , Tejedor, G. , Mausset-Bonnefont, A-L. , Beaulieu, E. V. , Morand, E. F. , Jorgensen, C. , Noel, D. & Farida, D. 2015 In : Arthritis & Rheumatology. 67, 6, p. 1514 - 1524 11 p. Research - peer-review › Article