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研究领域

Proteases and Protease inhibitors in cancer, infection and immunity Pore forming proteins in health and disease

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Teoh SS, Vieusseux J, Prakash M, Berkowicz S, Luu J, Bird CH, Law RH, Rosado C, Price JT, Whisstock JC, Bird PI. Maspin is not required for embryonic development or tumour suppression. Nat Commun. 2014 Jan 20;5:3164. doi: 10.1038/ncomms4164. Wang M, Zhao XM, Tan H, Akutsu T, Whisstock JC, Song J. Cascleave 2.0, a new approach for predicting caspase and granzyme cleavage targets. Bioinformatics. 2014 Jan 1;30(1):71-80. doi: 10.1093/bioinformatics/btt603. Epub 2013 Oct 21. Pang SS, Nguyen ST, Perry AJ, Day CJ, Panjikar S, Tiralongo J, Whisstock JC, Kwok T. The three-dimensional structure of the extracellular adhesion domain of the sialic acid-binding adhesin SabA from Helicobacter pylori. J Biol Chem. 2013 Dec 27. [Epub ahead of print] Li SH, Reinke AA, Sanders KL, Emal CD, Whisstock JC, Stuckey JA, Lawrence DA. Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc Natl Acad Sci U S A. 2013 Dec 2. [Epub ahead of print] Law RH, Abu-Ssaydeh D, Whisstock JC. New insights into the structure and function of the plasminogen/plasmin system. Curr Opin Struct Biol. 2013 Nov 16. doi:pii: S0959-440X(13)00182-6. 10.1016/j.sbi.2013.10.006. [Epub ahead of print]

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