研究领域

Biomedical Engineering Cellular Biomechanics (cell migration, mechanobiology) Cellular Systems Biology (cardiac, cancer) Computational Cell Biology (cardiac, cancer) Electron microscopy and tomography (cardiac cell, ultrastructure) Microfluidics cell culturing and imaging (cancer cell motility) soft tissue mechanics (breast cancer image analysis)

Current research projects include: Cardiac cell systems biology and mechanobiology in diseases such as diabetic cardiomyopathy and cardiac hypertrophy Multi-scale modelling of cellular mechanobiology. Red blood cell mechanics and malaria Breast tissue mechanics with applications in breast cancer diagnosis Single ventricle heart mechanics

近期论文

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Rajagopal V, Bass G, Walker CG, Crossman DJ, Petzer A, Hickey A, Siekmann I, Hoshijima M, Ellisman MH, Crampin E, Soeller C. Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca2+ Release Patterns in Cardiomyocytes. PLOS COMPUTATIONAL BIOLOGY. Public Library of Science. 2015, Vol. 11, Issue 9. Hou Y, Crossman DJ, Rajagopal V, Baddeley D, Jayasinghe I, Soeller C. Super-resolution fluorescence imaging to study cardiac biophysics: alpha-actinin distribution and Z-disk topologies in optically thick cardiac tissue slices. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY. Pergamon. 2014, Vol. 115, Issue 2-3. Lee AWC, Rajagopal V, Gamage TPB, Doyle AJ, Nielsen PMF, Nash MP. Breast lesion co-localisation between X-ray and MR images using finite element modelling. Medical Image Analysis. Elsevier Science. 2013, Vol. 17, Issue 8. Gamage TPB, Boyes R, Rajagopal V, Nielsen PMF, Nash MP. Modelling Prone to Supine Breast Deformation Under Gravity Loading Using Heterogeneous Finite Element Models. Computational Biomechanics for Medicine. Springer. 2012. Editors: Nielsen PMF, Wittek A, Miller K. Rajagopal V, Khwaounjoo P, Walker CG, O'Sullivan M, Soeller C. Subcellular Structural Changes in Diabetic Cardiomyopathy and its Impact on Cardiac Cell Calcium Dynamics. 56th Annual Meeting of the Biophysical-Society. Biophysical Society. 2012, Vol. 102, Issue 3. Yan J, Walker CG, O'Sullivan MJ, Bushong EA, Ellisman MH, Hoshijima M, Rajagopal V. Visualization, Modeling, and Spatial Statistics of Mitochondrial Assembly in Adult Cardiomyocytes using Serial Block-Face Scanning Electron Microscopy. 56th Annual Meeting of the Biophysical-Society. Biophysical Society. 2012, Vol. 102, Issue 3. Babarenda Gamage TP, Rajagopal V, Ehrgott M, Nash MP, Nielsen PMF. Identification of mechanical properties of heterogeneous soft bodies using gravity loading. International Journal for Numerical Methods in Biomedical Engineering. John Wiley & Sons. 2011, Vol. 27, Issue 3. Gamage TPB, Rajagopal V, Ehrgott M, Nash MP, Nielsen PMF. Identification of mechanical properties of heterogeneous soft bodies using gravity loading (vol 27, pg 371, 2011). INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING. John Wiley & Sons. 2011, Vol. 27, Issue 4. Reynolds HM, Puthran J, Doyle A, Jones W, Nielsen PMF, Nash MP, Rajagopal V. Mapping Breast Cancer Between Clinical X-Ray and MR Images. 5th Computational Biomechanics for Medicine Workshop/Medical Image Computing and Computer Assisted Intervention Conference (MICCAI). Springer. 2011. Bradley C, Bowery A, Britten R, Budelmann V, Camara O, Christie R, Cookson A, Frangi AF, Gamage TB, Heidlauf T, Krittian S, Ladd D, Little C, Mithraratne K, Nash M, Nickerson D, Nielsen P, Nordbo O, Omholt S, Pashaei A, Paterson D, Rajagopal V, Reeve A, Roehrle O, Safaei S, Sebastian R, Steghoefer M, Wu T, Yu T, Zhang H, Hunter P. OpenCMISS: A multi-physics & multi-scale computational infrastructure for the VPH/Physiome project. Progress in Biophysics & Molecular Biology. Pergamon. 2011, Vol. 107, Issue 1.