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个人简介

博士(后),教授,博士及硕士研究生导师,湖南科技大学教育部重点实验室专职科研人员,中国化学会会员。近年来,先后共主持各类科研项目10来项。2010年获广东省优秀博士学位论文,2011年获全国优秀博士学位论文提名奖,2014年获湖南省化学化工学会第十三届青年化学化工奖,2019年湖南省121创新人才第三层次。在《Advanced Functional Materials》、《Small》、《Macromolecules》、《Chemical Communications》、《Polymer Chemistry》等国内外杂志上发表SCI论文60余篇,引用1800余次,其中ESI高被引论文3篇,H指数为25。申请发明专利20余项,授权14项。

近期论文

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Sheng Wang, Hong Wang, Peisheng Zhang, Lulu Xue, Jian Chen* and Jiaxi Cui*, Folding Fluorescent Probes for Self-Reporting Transesterification in Dynamic Polymer Networks. Materials Horizons , 2021, DOI: 10.1039/D0MH02024A. Hui Liu, Peisheng Zhang*, Chonghua Zhang, Jian Chen* and JianHui Jiang*, Self-assembly of dual targeting and self-calibrating ratiometric polymer nanoprobe for accurate hypochlorous acid imaging. ACS Applied Materials & Interfaces , 2020, 12 (41): 45822–45829. Hong Wang, Peisheng Zhang,* Chonghua Zhang, Shu Chen, Rongjin Zeng, Jiaxi Cui and Jian Chen*, A rational design of a cancer-specific and lysosome-targeted fluorescence nanoprobe for glutathione imaging in living cells. Materials Advances , 2020, 1: 1739-1744. Jie Liu, Yubing Zhang, Chonghua Zhang, Peisheng Zhang, Rongjin Zeng*, Jiaxi Cui*, Jian Chen* Perylene diimide-based supramolecular polymer with temperature-sensitive ratiometric fluorescence responsiveness in solution and gels. Materials Advances , 2020, 1: 1330-1336. Mingju Xue, Jian Chen*, Yubin Zhang, Le Liu, Yuqi Li, Chonghua Zhang, Peisheng Zhang*, Susanne Sihler, and Ulrich Ziener,* Dual Function of Eosin Y in Miniemulsion Polymerization: Stabilizer and FRET Acceptor. European Polymer Journal 2020, 134: 109862. Hongqing Wei, Rongjin Zeng,* Shenglan Wang, Chong-Hua Zhang, Shu Chen, Peisheng Zhang* Jian Chen*, Engineering of a zero cross-talk fluorescent polymer nanoprobe for self-referenced ratiometric imaging of lysosomal hypochlorous acid in living cells. Materials Chemistry Frontiers 2020, 4(3): 862-868. Junyu Ren, Peisheng Zhang*, Hui Liu, Chonghua Zhang, Shu Chen, Rongjin Zeng, Yong Gao*, Jiaxi Cui, Jian Chen*, Single-chromophore-based fluorescent nanoprobe enables self-referenced ratiometric imaging of hypochlorous acid in lyso-somes. Sensors and Actuators B 2020, 304: 127299. Hong Wang1, Jing Wei1, Chonghua Zhang*, Yuan Zhang, Yubin Zhang, Lin Li, Changmin Yu*, Peisheng Zhang, Jian Chen*, Red carbon dots as label-free two-photon fluorescent nanoprobes for imaging of formaldehyde in living cells and zebrafishes. Chinese Chemical Letters , 2020, 31: 759-763. Sheng Wang, Li Yang, Hong Wang, Lulu Xue, Jian Chen*, Jiaxi Cui*, Nonequilibrium Transesterification for Programming a Material's Stiffening. ACS Applied Polymer Materials 2019, 1: 3227-3232. Zhong Lin1, Hong Wang1, Maolin Yu, Xiang Guo, Chonghua Zhang, Haitao Deng, Peisheng Zhang, Shu Chen, Rongjin Zeng, Jiaxi Cui*, Jian Chen*, Photoswitchable ultrahigh-brightness red fluorescent polymeric nanoparticles for information encryption, anti-counterfeiting and bioimaging. Journal of Materials Chemistry C , 2019, 7: 11515-11521. Ying Liu, Chonghua Zhang*, Peisheng Zhang, Hong Wang, Jinwen Liu, Shenglan Wang, Rongjin Zeng*, Shu Chen, Jian Chen*, Block copolymer nanoparticles-based fluorescent sensor for ultrasensitive detection of tyrosinase activity and inhibitor. Sensors and Actuators B 2019, 298: 126935. Hong Wang1, Yanyang He1, Yuqi Li, Chonghua Zhang, Peisheng Zhang*, Jiaxi Cui, Yunfei Long, Shu Chen, Rongjin Zeng, Jian Chen*, Selective ratiometric fluorescence detection of hypochlorite by using aggregation-induced emission dots. Analytical and Bioanalytical Chemistry , 2019, 411: 1979-1988. Maolin Yu, Hong Wang, Yuqi Li, Peisheng Zhang*, Shu Chen, Rongjin Zeng, Yong Gao*, Jian Chen*, Photoswitchable diarylethene-based polyurethane film for photorewritable patterning and stable information storage. Journal of Applied Polymer Science 2019, 136(20): 47466. Yongxiang Hong, Hong Wang, Mingju Xue, Peisheng Zhang*, Wanqiang Liu, Shu Chen, Rongjin Zeng, Jiaxi Cui, Yong Gao*, and Jian Chen*, Rational design of a ratiometric and lysosome-targetable AIE dots for imaging endogenous HClO in live cells. Materials Chemistry Frontiers 2019, 3: 203-208. Mingju Xue1, Hong Wang1, Jian Chen*, Junyu Ren, Shu Chen, Heping Yang, Rongjin Zeng, Yunfei Long and Peisheng Zhang*, Ratiometric fluorescent sensing of endogenous hypochlorous acid in lysosomes using AIE-based polymeric nanoprobe. Sensors and Actuators B 2019, 282: 1-8. Chong-Hua Zhang, Hong Wang, Jin-Wen Liu, Ying-Ying Sheng, Jian Chen*, Peisheng Zhang, Jian-Hui Jiang*, Amplified Split Aptamer Sensor Delivered Using Block Copolymer Nanoparticles for Small Molecule Imaging in Living Cells. ACS Sensors 2018, 3, 2526−2531. Maolin Yu1, Peisheng Zhang1, Baiju P. Krishnan, Hong Wang, Yong Gao*, Shu Chen, Rongjin Zeng, Jiaxi Cui*, and Jian Chen*, From a Molecular Toolbox to a Toolbox for Photoswitchable Fluorescent Polymeric Nanoparticles. Advanced Functional Materials, 2018, 28: 1804759. Hong Wang1, Peisheng Zhang1, Baiju P. Krishnan, Maolin Yu, Jie Liu, Mingju Xue, Shu Chen, Rongjin Zeng, Jiaxi Cui* and Jian Chen*, Switchable single fluorescent polymeric nanoparticles for stable white-light generation. Journal of Materials Chemistry C, 2018, 6: 9897-9902. Peisheng Zhang*, Yong Tian, Hui Liu, Junyu Ren, Hong Wang, Rongjin Zeng, Yunfei Long and Jian Chen, In vivo imaging of hepatocellular nitric oxide using a hepatocyte-targeting fluorescent sensor, Chemical Communications, 2018, 54: 7231-7234. Hong Wang, Peisheng Zhang*, Yong Tian, Yuan Zhang, Heping Yang, Shu Chen, Rongjin Zeng*, Yunfei Long, Jian Chen*. Real-time monitoring of endogenous cysteine levels in living cells using a CD-based ratiometric fluorescent nanoprobe. Analytical and Bioanalytical Chemistry, 2018, 410: 4379-4386. Yongxiang Hong, Peisheng Zhang*, Hong Wang, Maolin Yu, Yong Gao*, Jian Chen*. Photoswitchable AIE nanoprobe for lysosomal hydrogen sulfide detection and reversible dual-color imaging. Sensors and Actuators B 2018, 272: 340-347. Peisheng Zhang, Hong Wang, Di Zhang, Xuyao Zeng, Rongjin Zeng,* Lehui Xiao*, Hongwen Tao Yunfei Long, Pinggui Yi, and Jian Chen*. Two-photon fluorescent probe for lysosome-targetable hypochlorous acid detection within living cells. Sensors and Actuators B 2018, 255: 2223-2231. Peisheng Zhang*, Hong Wang, Yongxiang Hong, Maolin Yu, Rongjin Zeng, Yunfei Long, Jian Chen*. Selective visualization of endogenous hypochlorous acid in zebrafish during lipopolysaccharide-induced acute liver injury using a polymer micelles-based ratiometric fluorescent probe. Biosensors and Bioelectronics 2018, 99: 318–324. Peisheng Zhang,1 Yongxiang Hong,1 Hong Wang, Maolin Yu, Yong Gao,*, Rongjin Zeng,* Yunfei Long and Jian Chen*. Selective visualization of endogenous hydrogen sulfide in lysosomes via using aggregation induced emission dots. Polymer Chemistry 2017, 8: 7271 - 7278. Jian Chen,* Weibang Zhong, Mingju Xue, Hong Wang, Maolin Yu, Peisheng Zhang* and Pinggui Yi*. Photochromic RAFT reagent helps constructing superior photoswitchable fluorescent polymer nanoparticles for rewritable fluorescence patterning and intracellular dual-color imaging. Polymer Chemistry 2017, 8: 6520-6526. Hong Wang, Peisheng Zhang,* Yongxiang Hong, Bin Zhao, Pinggui Yi and Jian Chen*. Ratiometric imaging of lysosomal hypochlorous acid enabled by FRET-based polymer dots. Polymer Chemistry 2017, 8: 5795-5802. Weibang Zhong1, Xuyao Zeng1, Jian Chen*, Yongxiang Hong, Lehui Xiao and Peisheng Zhang*. Photoswitchable fluorescent polymeric nanoparticles for rewritable fluorescence patterning and intracellular dual-color imaging with AIE-based fluorogens as FRET donors. Polymer Chemistry 2017, 8: 4849-4855. Jian Chen*, Chonghua Zhang, Kun Lv, Hong Wang, Peisheng Zhang*, Pinggui Yi, Jianhui Jiang*. A silica nanoparticle-based dual-responsive ratiometric probe for visualizing hypochlorite and temperature with distinct fluorescence signals. Sensors and Actuators B 2017, 251: 533-541. Jian Chen, Adam W. Ziegler, Baoming Zhao, Wei Wan and Alexander D. Q. Li*. Chemomechanical-force-induced folding–unfolding directly controls distinct fluorescence dual-color switching. Chemical Communications, 2017, 53, 4993-4996. Hong Wang1, Peisheng Zhang1, Jian Chen*, Ya Li, Maolin Yu, Yunfei Long, Pinggui Yi. Polymer nanoparticle-based ratiometric fluorescent probe for imaging Hg2+ ions in living cells. Sensors and Actuators B 2017, 242: 818-824. Kun Lv, Jian Chen*, Hong Wang, Peisheng Zhang*, Maolin Yu, Yunfei Long, Pinggui Yi. One-pot fabrication of FRET-based fluorescent probe for detecting copper ion and sulfide anion in 100% aqueous media. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2017, 177, 63-68. Hong Wang, Jian Chen*, Yongxiang Hong, Kun Lv, Maolin Yu, Peisheng Zhang*, Yunfei Long, and Pinggui Yi. Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum. Analytical Sciences 2017, 33, 591-597. Jian Chen*, Ying Tang, Hong Wang, Peisheng Zhang*, Ya Li and Jianhui Jiang*. Design and fabrication of fluorescence resonance energy transfer-mediated fluorescent polymer nanoparticles for ratiometric sensing of lysosomal pH, Journal of Colloid and Interface Science 2016, 484: 298-307. Jian Chen*, Ya Li, Kun lv, Weibang Zhong, Hong Wang, Zhan Wu*, Pinggui Yi* and Jianhui Jiang. Cyclam-Functionalized Carbon Dots Sensor for Sensitive and Selective Detection of Copper(II) Ion and sulfide anion in Aqueous Media and Its Imaging in Live Cells. Sensors and Actuators B 2016, 224: 298-306. Jian Chen,* Ya Li, Weibang Zhong, Hong Wang, Peisheng Zhang* and Jianhui Jiang. A highly selective fluorescent and colorimetric chemosensor for Hg2+ based on a new rhodamine derivative. Analytical Methods 2016, 8: 1964-1967. Jian Chen,* Weibang Zhong, Ying Tang, Zhan Wu, Ya Li, Pinggui Yi,* Jianhui Jiang*. Amphiphilic BODIPY-Based Photoswitchable Fluorescent Polymeric Nanoparticles for Rewritable Patterning and Dual-Color Cell Imaging. Macromolecules 2015, 48: 3500-3508. Jian Chen*, Ya Li, Weibang Zhong, Qingyang Hou, Hong Wang, Xiang Sun and Pinggui Yi. Novel fluorescent polymeric nanoparticles for highly selective recognition of copper ion and sulfide anion in water. Sensors and Actuators B 2015, 206: 230-238. Jian Chen*, Fuhua Huang, Hong Wang, Ya Li, Shengli Liu, Pinggui Yi. One-pot preparation of multicolor polymeric nanoparticles with high brightness by single wavelength excitation. Journal of Applied Polymer Science 2015, 132: 41492. Bo Liao*, Peng Long, Benqiao He*, Shoujun Yi, Baoli Ou, Shaohua Shen, Jian Chen*. Reversible Fluorescence Modulation of Spiropyrans-functionalized Carbon Nanoparticles. Journal of Materials Chemistry C 2013, 1: 3716-3721. Peisheng Zhang, Jian Chen*, Fuhua Huang, Zhiqiang Zeng, Jia Hu, Pinggui Yi*, Fang Zeng and Shuizhu Wu. One-pot fabrication of polymer nanoparticle-based chemosensor for Cu2+ detection in aqueous media. Polymer Chemistry 2013, 4: 2325-2332. Jian Chen*, Dapeng Wang, Andrey Turshatov, Rafael Muñoz-Espí, Ulrich Ziener,* Kaloian Koynov, Katharina Landfester*. One-pot Fabrication of Amphiphilic Photoswitchable Thiophene-Based Fluorescent Polymer Dots. Polymer Chemistry 2013, 4: 773-781. Jian Chen, Jie Shu, Simone Schobloch, Anja Kroeger, Robert Graf, Rafael Muñoz-Espí, Katharina Landfester, and Ulrich Ziener*. A New Design Strategy for the Synthesis of Unsubstituted Polythiophene with Defined High Molecular Weight. Macromolecules 2012, 45: 5108-5113. Jian Chen*, Peisheng Zhang, Gang Fang, Chao Weng, Jia Hu, Pinggui Yi*, Xianyong Yu and Xiaofang Li. One-pot synthesis of amphiphilic reversible photoswitchable fluorescent nanoparticles and their fluorescence modulation properties. Polymer Chemistry 2012, 3: 685-693. Jian Chen*, Peisheng Zhang, Gang Fang, Pinggui Yi*, Fang Zeng and Shuizhu Wu. Design and Synthesis of FRET-Mediated Multicolor and Photoswitchable Fluorescent Polymer Nanoparticles with Tunable Emission Properties. Journal of Physical Chemistry B 2012, 116(14):4354-4362. Jian Chen, Peisheng Zhang, Gang Fang, Pinggui Yi*, Xianyong Yu, Xiaofang Li, Fang Zeng* and Shuizhu Wu. Synthesis and Characterization of Novel Reversible Photoswitchable Fluorescent Polymeric Nanoparticles via One-Step Miniemulsion Polymerization. Journal of Physical Chemistry B 2011, 115(13): 3354-3362.

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