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个人简介

招生专业 071007-遗传学 招生方向 树鼩疾病模型建立与遗传 教育背景 2002-09--2005-06 南京农业大学 硕士 1998-09--2002-06 南京农业大学 本科 工作简历 2007-12~现在, 中国科学院昆明动物研究所, 副研究员 2005-07~2007-11,中国农业科学院上海兽医研究所, 研究实习员 2002-09~2005-06,南京农业大学, 硕士 1998-09~2002-06,南京农业大学, 本科 奖励信息 (1) Leber遗传性视神经病遗传易感研究, 二等奖, 省级, 2015 科研项目 ( 1 ) lncRNA调控树鼩天然免疫反应及影响HCV复制的机制研究, 主持, 省级, 2018-06--2021-05 ( 2 ) 线粒体MAVS基因3'UTR在家鸡抗病毒感染过程中的作用机制研究, 主持, 国家级, 2011-01--2013-12 ( 3 ) 树鼩基因组数据库与生物信息平台搭建, 主持, 省级, 2013-10--2016-09 ( 4 ) 树鼩HCV进入因子EphA2影响HCV复制及持续性感染的研究, 主持, 省级, 2020-06--2023-05

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(1) An alternative splicing of Tupaia STING modulated anti-RNA virus responses by targeting MDA5-LGP2 and IRF3., The Journal of Immunology, 2020, 第 2 作者 (2) Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I., Journal of Genetics and Genomics, 2019, 第 2 作者 (3) Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis), Developmental and Comparative Immunology, 2019, 第 2 作者 (4) Establishment and characterization of an immortalized renal cell line of the Chinese tree shrew (Tupaia belangeri chinesis), Applied Microbiology and Biotechnology, 2019, 第 2 作者 (5) Molecular characterization of the 2′,5′-oligoadenylate synthetase family in the Chinese tree shrew (Tupaia belangeri chinensis), Cytokine, 2019, 第 2 作者 (6) Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew, Proceedings of the National Academy of Sciences of the United States of America, 2016, 第 1 作者 (7) Identification and characterization of toll-like receptors (TLRs) in the Chinese tree shrew (Tupaia belangeri chinensis), Developmental and Comparative Immunology, 2016, 第 1 作者 (8) Diverse interleukin-7 mRNA transcripts in Chinese tree shrew (Tupaia belangeri chinensis), PLoS One, 2014, 第 1 作者 (9) Genetic variations of mitochondrial antiviral signaling gene (MAVS) in domestic chickens, Gene, 2014, 第 1 作者 (10) IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma, Medical Science Monitor, 2014, 通讯作者 (11) Mitochondrial DNA sequence variation and haplogroup distribution in Chinese patients with LHON and m.14484T>C, PLoS One, 2010, 第 1 作者 (12) Molecular characterization of six Chinese families with m.3460G>A and Leber hereditary optic neuropathy, Neurogenetics, 2010, 第 1 作者 (13) Reverse genetic manipulation of the overlapping coding regions for structural proteins of the type II porcine reproductive and respiratory syndrome virus, Virology, 2009, 第 1 作者

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