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个人简介

招生专业 071010-生物化学与分子生物学 招生方向 病毒感染与天然免疫 病毒分子流行病学 教育背景 2001-09--2004-08 中科院武汉病毒所 博士 1999-09--2000-09 荷兰Wageningen大学 合作研究 工作简历 2002-09~现在, 中科院武汉病毒所, 研究员 2001-09~2004-08,中科院武汉病毒所, 博士 1999-09~2000-09,荷兰Wageningen大学, 合作研究 1995-09~2002-09,中科院武汉病毒所, 副研究员 1993-04~1994-08,瑞典国家兽医研究所, 访问学者 1980-01~1993-01,中国科学院武汉病毒所, 助研 教授课程 动物病毒学 生物技术 专利成果 ( 1 ) 带有棉铃虫单粒包埋核型多角体病毒基因核P10基因启动子序列的快速供体质粒及构建方法, 2007, 第 1 作者, 专利号: ZL01138376 ( 2 ) 一种EV71病毒的化学发光免疫成像检测方法, 2010, 第 1 作者, 专利号: 201010542645X 发表著作 ( 1 ) 普通病毒学, Virology, 科学出版社, 2002-08, 第 4 作者 ( 2 ) 人畜共患病, Zoonotic Diseases, 湖北科技出版社, 2006-09, 第 5 作者 科研项目 ( 1 ) 量子点标记病毒研究病毒侵入和免疫应答, 参与, 国家级, 2011-01--2015-12 ( 2 ) EV71神经毒性靶点的鉴定及致病机理研究, 主持, 国家级, 2011-01--2013-12 ( 3 ) 传染病病原体检测技术平台, 参与, 国家级, 2008-10--2011-12

近期论文

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(1) Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus ORF51, a Highly Conserved Gene, is Involved in the Budded Virus Production, Virus Research , 2011, 通讯作者 (2) . Enterovirus 71 2C protein inhibits TNF-α mediated activation of NF-κB through preventing IκB kinase β phosphorylation by direct binding, Journal of Immunology, 2011, 通讯作者 (3) Detection of, and frequent co-infection with, human bocavirus in faecal specimens from children in Wuhan, China., Clinical microbiology and infection, 2010, 通讯作者 (4) Effect of Mucosal and Systemic Immunization with Virus-Like Particles of SARS-CoV in Mice., Immunology, 2010, 通讯作者 (5) The cysteine protease domain 1 of porcine reproductive and respiratory syndrome virus nonstructural protein 2 antagonizes 3 IRF-3 activation., Journal of General Virology , 2010, 通讯作者 (6) Modulation of Immune Response to Orf 3a protein of the SARS coronavirus and SARS like coronavirus by Gene-Based immunization in mice, Clinical and Vaccine Immunology, 2009, 通讯作者 (7) Comparative analysis the immunogenicity of SARS-CoV nucleocapsid DNA vaccine administrated with different routes in mouse model., Vaccine, 2009, 通讯作者 (8) Vaccination of Mice with Recombinant Baculovirus Expressing Spike or Nucleocapsid Protein of SARS-Like Coronavirus Generates Humoral and Cellular Immune Responses, Molecular Immunology, 2008, 通讯作者 (9) Virus-Like Particles of SARS-Like Coronavirus Formed by Membrane Proteins from Different Origins Demonstrate Stimulating Activity in Human Dendritic Cells, Plos One, 2008, 通讯作者 (10) Specific immune responses induced by SARS-CoV spike DNA vaccine with or without interleukin-2 immunized via different immune routes in mice., Clinical and Vaccine Immunology, 2007, 通讯作者 (11) Immune Responses Against SARS CoV Induced by Virus-Like Particles in Mice, Immunology, 2007, 通讯作者 (12) Construction and Characterization of a Helicoverpa armigera nucleopolyhedrovirus bacterial artificial chromosome with deletion of UDP-glycosyltransferase, Bioscience, Biotechnology, and Biochemistry, 2007, 通讯作者 (13) Emergence of Human Rotavirus Group A Genotype G9 Strains in Wuhan, China., Emerging Infectious Disease, 2007, 通讯作者 (14) Natural Mutations in the Receptor Binding Domain of Spike Glycoprotein Determine the Reactivity of Cross-Neutralization between Palm Civet Coronavirus and Severe Acute Respiratory Syndrome Coronavirus, Journal of Virology, 2007, 通讯作者

学术兼职

2007-09-06-今,湖北省生物工程学会, 常务理事 2005-03-15-今,湖北省遗传学会, 常务理事

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