Stewart, Scott - University of Western Australia - School of Chemistry and Biochemistry

研究领域

1. The efficient synthesis of natural products and their simplified ring systems. 2. The development of palladium and nickel catalysed cross coupling reactions 3. The use of domino type reactions in organic synthesis 4. The synthesis of new nickel catalysts 5. Medicinal chemistry: antibacterial agents; thalidomide analogues; anti-cancer agents

近期论文

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tewart, S. 2014, Modern Domino Reactions Containing a Michael Addition Reaction in Domino Reactions: Concepts for Efficient Organic Synthesis, Wiley-VCH , Germany Detail Stewart, S. 2013, Formation of Heterocycles in Science of Synthesis Cross Coupling and Heck-Type Reactions 3, Thieme , Germany Detail Tietze, LF, Stewart, S., Dufert, A. 2012, Domino reactions in the Enantioselective synthesis of bioactive natural products in Modern Tools for the Synthesis of Complex Bioactive Molecules, John Wiley & Sons Inc , United States and Canada Detail Woo, K., Stewart, S.G., Kong, G.S., Finch-Edmondson, M.L., Dwyer, B.J., Yeung, S.Y., Abraham, L.J., Kampmann, S.S., Diepeveen, L.A., Passman, A.M., Elsegood, C.L., Tirnitz-Parker, J.E.E., Callus, B.A., Olynyk, J.K., Yeoh, G.C.T. 2016, 'Identification of a thalidomide derivative that selectively targets tumorigenic liver progenitor cells and comparing its effects with lenalidomide and sorafenib', European Journal of Medicinal Chemistry, 120, pp. 275-283. Detail Shi, M.W., Sobolev, A.N., Schirmeister, T., Engels, B., Schmidt, T.C., Luger, P., Mebs, S., Dittrich, B., Chen, Y., Bak, J.M., Jayatilaka, D., Bond, C.S., Turner, M.J., Stewart, S.G., Spackman, M.A., Grabowsky, S. 2015, 'Electrostatic complementarity in pseudoreceptor modeling based on drug molecule crystal structures: The case of loxistatin acid (E64c)', New Journal of Chemistry, 39, pp. 1628-1633. Detail Shen, C., Man, N.Y.T., Stewart, S.G., Wu, X. 2015, 'Palladium-catalyzed dicarbonylative synthesis of tetracycle quinazolinones', Organic and Biomolecular Chemistry, 13, 15, pp. 4422-4425. Detail Chen, J., Natte, K., Man, N.Y.T., Stewart, S.G., Wu, X.F. 2015, 'Convenient copper-mediated Chan-Lam coupling of 2-aminopyridine: Facile synthesis of N-arylpyridin-2-amines', Tetrahedron Letters, 56, 33, pp. 4843-4847. Detail Rixson, J.E., Abraham, J.R., Egoshi, Y., Skelton, B.W., Young, K., Gilbert, J., Sakoff, J.A., Gericke, K.M., McCluskey, A., Stewart, S.G. 2015, 'The synthesis and biological activity of novel anthracenone-pyranones and anthracenone-furans', Bioorganic and Medicinal Chemistry, 23, 13, pp. 3552-3565. Detail Kampmann, S.S., Skelton, B.W., Wild, D.A., Koutsantonis, G.A., Stewart, S.G. 2015, 'An Air-Stable Nickel(0) Phosphite Precatalyst for Primary Alkylamine C-N Cross-Coupling Reactions', European Journal of Organic Chemistry, 2015, 27, pp. 5995-6004. Detail Jones, K.D., Rixson, J.E., Skelton, B.W., Gericke, K.M., Stewart, S.G. 2015, 'The Total Synthesis of Heraclemycin B through ß-Ketosulfoxide and Aldehyde Annulation', Asian Journal of Organic Chemistry, 4, 9, pp. 936-942. Detail Man, N.Y.T., Li, W., Stewart, S.G., Wu, X.F. 2015, 'Transition metal-free methylation of amines with formaldehyde as the reductant and methyl source', Chimia, 69, 6, pp. 345-347. Detail Kampmann, S.S., Skelton, B.W., Yeoh, G.C., Abraham, L.J., Lengkeek, N.A., Stubbs, K.A., Heath, C.H., Stewart, S.G. 2015, 'The synthesis and fluorescence profile of novel thalidomide analogues', Tetrahedron, 71, 42, pp. 8140-8149. Detail Kampmann, S.S., Man, N.Y.T., McKinley, A.J., Koutsantonis, G.A., Stewart, S.G. 2015, 'Exploring the Catalytic Reactivity of Nickel Phosphine-Phosphite Complexes', Australian Journal of Chemistry, 68, 12, pp. 1842-1853. Detail Kampmann, S.S., Skelton, B.W., Wild, D.A., Koutsantonis, G.A., Stewart, S.G. 2015, 'Tris(tri-o-tolyl phosphite-κP)nickel: a coordinatively unsaturated nickel(0) complex ', ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 71, pp. 188-190. Detail Kampmann, S.S., Sobolev, A.N., Koutsantonis, G.A., Stewart, S.G. 2014, 'Stable nickel(0) phosphites as catalysts for C-N cross-coupling reactions', ADVANCED SYNTHESIS & CATALYSIS, 356, 9, pp. 1967-1973. Detail Miura, T., Tanaka, T., Hiraga, K., Stewart, S.G., Murakami, M. 2013, 'Stereoselective synthesis of 2,3-dihydropyrroles from terminal alkynes, azides, and α,β-unsaturated aldehydes via N-sulfonyl-1,2,3-triazoles', Journal of the American Chemical Society, 135, 37, pp. 13652-13655. Detail Rixson, J.E., Skelton, B.W., Koutsantonis, G.A., Gericke, K.M., Stewart, S.G. 2013, 'Domino reactions for the Synthesis of Anthrapyran-2-ones and the Total Synthesis of the Natural Product (±)-BE-26554A', Organic Letters, 15, 18, pp. 4834-4837. Detail Boulos, R.A., Man, N.Y.T., Lengkeek, N.A., Hammer, K.A., Foster, N.F., Stemberger, N.A., Skelton, B.W., Wong, P.Y., Martinac, B., Riley, T.V., McKinley, A.J., Stewart, S.G. 2013, 'Inspiration from old dyes: Tris(stilbene) compounds as potent gram-positive antibacterial agents', Chemistry - A European Journal, 19, 52, pp. 17980-17988. Detail Eroglu, E., Chen, X., Bradshaw, M.S., Agarwal, V., Zou, J., Stewart, S., Duan, X., Lamb, R.N., Smith, S.M., Raston, C.L., Swaminatha Iyer, K.L. 2013, 'Biogenic production of palladium nanocrystals using microalgae and their immobilization on chitosan nanofibers for catalytic applications', RSC Advances: an international journal to further the chemical sciences, 3, 4, pp. 1009-1012. Detail Rixson, J.E., Chaloner, T., Heath, C.H., Tietze, L.F., Stewart, S.G. 2012, 'The development of domino reactions incorporating the heck reaction: The formation of N-heterocycles', European Journal of Organic Chemistry, NA, pp. 544–558. Detail