Attwood, Paul - University of Western Australia - School of Chemistry and Biochemistry

研究领域

Enzymology, protein-histidine phosphorolation Structure and function of pyruvate carboxylase Investigation of histidine kinases and their role in mammalian cell biology

近期论文

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Arthur, P., Ludwig, M., Castelli, J., Kirkwood, P., Attwood, P. 2016, 'Prepare, Do, Review: A skills-based approach for laboratory practical classes in biochemistry and molecular biology', Biochemistry and Molecular Biology Education, 44, 3, pp. 276-287. Detail Sirithanakorn, C., Jitrapakdee, S., Attwood, P.V. 2016, 'Investigation of the Roles of Allosteric Domain Arginine, Aspartate, and Glutamate Residues of Rhizobium etli Pyruvate Carboxylase in Relation to Its Activation by Acetyl CoA', Biochemistry, 55, 30, pp. 4220-4228. Detail Golden, E., Attwood, P.V., Duff, A.P., Meilleur, F., Vrielink, A. 2015, 'Production and characterization of recombinant perdeuterated cholesterol oxidase', Analytical Biochemistry, 485, pp. 102-108. Detail Choosangtong, K., Sirithanakorn, C., Adina-Zada, A., Wallace, J.C., Jitrapakdee, S., Attwood, P.V. 2015, 'Residues in the acetyl CoA binding site of pyruvate carboxylase involved in allosteric regulation', FEBS Letters, 589, 16, pp. 2073-2079. Detail Smith, N.E., Vrielink, A., Attwood, P.V., Corry, B. 2014, 'Binding and channeling of alternative substrates in the enzyme DmpFG: A molecular dynamics study', Biophysical Journal, 106, 8, pp. 1681-1690. Detail Adina-Zada, A., Jitrapakdee, S., Wallace, J.C., Attwood, P.V. 2014, 'Coordinating role of His216 in MgATP binding and cleavage in pyruvate carboxylase', Biochemistry, 53, 6, pp. 1051-1058. Detail Sirithanakorn, C., Adina-Zada, A., Wallace, J.C., Jitrapakdee, S., Attwood, P.V. 2014, 'Mechanisms of inhibition of Rhizobium etli pyruvate carboxylase by L-Aspartate', Biochemistry including biophysical chemistry & molecular biology, 53, 45, pp. 7100-7106. Detail Smith, N.E., Tie, W.J., Flematti, G.R., Stubbs, K.A., Corry, B., Vrielink, A., Attwood, P.V. 2013, 'Mechanism of the dehydrogenase reaction of DmpFG and analysis of inter-subunit channeling efficiency and thermodynamic parameters in the overall reaction', INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 45, 8, pp. 1878-1885. Detail Attwood, P.V. 2013, 'Histidine kinases from bacteria to humans', Biochemical Society Transactions, 41, pp. 1023-1028. Detail Mukai, S, Flematti, G.R, Byrne, L.T, Besant, P.G, Attwood, P.V, Piggott, M.J 2012, 'Stable triazolylphosphonate analogues of phosphohistidine', AMINO ACIDS, 22 November 2011, pp. 18pp. Detail Adina-Zada, A., Zeczycki, T.N., Attwood, P.V. 2012, 'Regulation of the structure and activity of pyruvate carboxylase by acetyl CoA', Archives of Biochemistry and Biophysics, 519, pp. 118–130. Detail Smith, N.E., Vrielink, A., Attwood, P.V., Corry, B. 2012, 'Biological Channeling of a Reactive Intermediate in the Bifunctional Enzyme DmpFG', BIOPHYSICAL JOURNAL, 102, pp. 868-877. Detail Adina-Zada, A., Zeczycki, T.N., St Maurice, M., Jitrapakdee, S., Cleland, W.W., Attwood, P.V. 2012, 'Allosteric regulation of the biotin-dependent enzyme pyruvate carboxylase by acetyl-CoA', Biochemical Society Transactions, 40, pp. 567-572. Detail Adina-Zada, A., Sereeruk, C., Jitrapakdee, S., Zeczycki, T.N., St. Maurice, M., Cleland, W.W., Wallace, J.C., Attwood, P.V. 2012, 'Roles of Arg427 and Arg472 in the Binding and Allosteric Effects of Acetyl CoA in Pyruvate Carboxylase', BIOCHEMISTRY, 51, pp. 8208−8217. Detail Adina-Zada, A., Hazra, R., Sereeruk, C., Jitrapakdee, S., Zeczycki, T.N., St Maurice, M., Cleland, W.W., Wallace, J.C., Attwood, P.V. 2011, 'Probing the allosteric activation of pyruvate carboxylase using 2 ',3 '-0-(2,4,6-trinitrophenyl) adenosine 5 '-triphosphate as a fluorescent mimic of the allosteric activator acetyl CoA', ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 509, pp. 117-126. Detail Zeczycki, T.N., Menefee, A.L., Adina-Zada, A., Jitrapakdee, S., Surinya, K.H., Wallace, J.C., Attwood, P.V., St Maurice, M., Cleland, W.W. 2011, 'Novel Insights into the Biotin Carboxylase Domain Reactions of Pyruvate Carboxylase from Rhizobium etli', BIOCHEMISTRY, 50, pp. 9724-9737. Detail Zeczycki, T.N., Menefee, A.L., Jitrapakdee, S., Wallace, J.C., Attwood, P.V., St Maurice, M., Cleland, W.W. 2011, 'Activation and Inhibition of Pyruvate Carboxylase from Rhizobium etli', BIOCHEMISTRY, 50, pp. 9694-9707. Detail Lietzan, A.D., Menefee, A.L., Zeczycki, T.N., Kumar, S., Attwood, P.V., Wallace, J.C., Cleland, W.W., St Maurice, M. 2011, 'Interaction between the Biotin Carboxyl Carrier Domain and the Biotin Carboxylase Domain in Pyruvate Carboxylase from Rhizobium etli', BIOCHEMISTRY, 50, pp. 9708-9723. Detail ATTWOOD, P.V., BESANT, P.G., PIGGOTT, M.J. 2011, 'Focus on phosphoaspartate and phosphoglutamate', Amino Acids, 40, pp. 1035-1051. Detail DUANGPAN, S., JITRAPAKDEE, S., ADINA-ZADA, A., BYRNE, L.T., ZECZYCKI, T.N., ST. MAURICE, M., CLELAND, W.W., WALLACE, J.C., ATTWOOD, P.V. 2010, 'Probing the Catalytic Roles of Arg548 and Gln552 in the Carboxyl Transferase Domain of the Rhizobium etli Pyruvate Carboxylase by Site-Directed Mutagenesis', Biochemistry, 49, pp. 3296-3304. Detail