郭彩欣 - 哈尔滨工业大学 - 生命科学与技术学院

个人简介

郭彩欣，女，副教授，硕士生导师。2007年7月于中国科学院化学研究所获理学博士学位。主要研究内容包括：1.多功能造影剂及诊疗试剂的研究。构建具有声、光、磁等多功能的造影剂，同时研究具有医学诊断和治疗作用的多功能诊疗一体化试剂；2. 纳米药物载体材料，研究可用于药物缓控释和靶向输送的纳米药物载体材料；3. 纳米生物传感器，基于纳米探针构建生物传感器，用于检测水中重金属污染物及农药残留。先后主持和参与国家自然科学基金、哈工大科研创新基金、国家重点实验室开放课题、国家863、教育部高等学校科技创新工程等多个项目的研究工作。在国际期刊Biosensors and Bioelectronics, Bioconjugate Chem., Langmuir, J. Phys.Chem B, Analyst 等杂志上发表SCI论文20余篇，获授权发明专利1项。教育经历 2004/9-2007/7，中科院化学所，胶体界面实验室，博士研究生 2001/9-2004/7，东北师范大学，化学学院，硕士研究生 1997/9-2001/7，东北师范大学，化学学院，本科工作经历 2007/7-至今，哈尔滨工业大学，生命科学与技术学院，副教授，硕导

研究领域

用于癌症诊断及治疗的多功能造影剂及诊疗一体化试剂的研究采用纳米技术检测水中痕量重金属污染物的研究药物缓控释载体材料的研究

近期论文

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Caixin Guo*, Donghao Liu, Wenbo Xu, Liangcan He, Shaoqin Liu*, Accelerating the peroxidase- and glucose oxidase-like activity of Au nanoparticles by seeded growth strategy and their applications for colorimetric detection of dopamine and glucose, Colloids and Surfaces A: Physicochemical and Engineering Aspects 658 (2023) 130555. Caixin Guo*, Jinliang Wang, Jing Cheng, Colorimetric sensing of copper (Ⅱ) ions based on the inhibition of biocatalytic growth of gold nanoparticles, Microchemical Journal 2020,157,105015. Zhaohua Miao, Caixin Guo, Zhenglin Li, Yushen Jin, Hengte Ke, Zhifei Dai, Fabrication of a multimodal microbubble platform for magnetic resonance, ultrasound and fluorescence imaging application, Journal of Nanoscience and Nanotechnology, 2016, 16, 2301-2306. Caixin Guo, Yushen Jin, and Zhifei Dai, Multifunctional ultrasound contrast agents for imaging guided photothermal therapy, Bioconjugate chem. 2014, 25, 840-854. Xiuli Yue*, Caixin Guo, Yuanmiao Jing, Fang Ma, Free-standing liposomal nanohybrid cerasomes as ideal materials for cupric ions sensing, Analyst, 2012, 137, 2027-2031. Caixin Guo, Jinliang Wang, Jing Cheng, Zhifei Dai, Determination of trace copper ions with ultrahigh sensitivity and selectivity utilizing CdTe quantum dots coupled with enzyme inhibition, Biosensor and Bioelectronics, 2012, 36, 69-74. Caixin Guo, Like Zeng, Shaoqin Liu, Qi Chen, Zhifei Dai, Xiaoyi Wu, In Vitro Evaluation and Finite Element Simulation of Drug Release from Polydiacetylene-Polyethylene Glycol Stearate Nanovesicles, J. Nanosci. Nanotech. 2012, 12, 245-251. Caixin Guo, Jinliang Wang, Zhifei Dai, Selective content release from light-responsive microcapsules by tuning the surface plasmon resonance of gold nanorods, Microchimica Acta, 2011, 173, 375-382. Hengte Ke, Jinrui Wang, Zhifei Dai, Yushen Jin, Enze Qu, Zhanwen Xing, Caixin Guo, Xiuli Yue, Jibin Liu, Gold nanoshelled microcapsules: a theranostic agent for ultrasound contrast imaging and photothermal therapy, Angew. Chem. Int. Edit., 2011, 50, 3017-3021 (IF 13.455). Hot paper. Highlighted by Nature Materials. Hengte Ke, Jinrui Wang, Zhifei Dai, Yushen Jin, Enze Qu, Zhanwen Xing, Caixin Guo, and Xiuli Yue, Bifunctional gold nanorod-loaded polymeric microcapsules for both contrast-enhanced ultrasound imaging and photothermal therapy, Journal of Materials Chemistry, 2011, 21, 5561-5564. Caixin Guo, Shaoqin Liu, Zhifei Dai, Chang Jiang, Wenyuan Li, Polydiacetylene vesicles as a novel drug sustained-release system, Colloids and Surfaces B: Biointerfaces 2010, 76, 362-365. Caixin Guo, Shaoqin Liu, Chang Jiang, Wenyuan Li, Zhifei Dai, Hiroe Fritz, Xiaoyi Wu, A Promising Drug Controlled-Release System Based on Diacetylene/Phospholipid Polymerized Vesicles, Langmuir 2009, 25, 13114-13119. Renzhe Zhang, Caixin Guo, Long Jiang, Tao Liu, The Fluorescence Recovery of Polydiacetylene/Fluorophore Vesicles by Interaction with Cetyltrimethylammonium Bromide，Journal of Nanoscience and Nanotechnology 2009, 9, 990-994. Caixin Guo, Paul Boullanger, Long Jiang, Tao Liu, One-Step Immobilization of Dodecanethiol/Glycolipid Vesicles onto Gold Electrode: Amperometric Detection of Concanavalin A，Colloids and Surfaces B: Biointerfaces 2008, 62, 146-150. Caixin Guo, Paul Boullanger, Long Jiang, Tao Liu, Highly Sensitive Gold Nanoparticles Biosensor Chips Modified with a Self-assembled Bilayer for Detection of Con A, Biosensor and Bioelectronics 2007, 22, 1830-1834. Caixin Guo, Paul Boullanger, Long Jiang, Tao Liu, Colorimetric Detection of WGA in Carbohydrate-functionalized Polydiacetylene Langmuir–Schaefer Films, Colloids and Surfaces A: Physicochem. Eng. Aspects 2007, 293, 152-156. Caixin Guo, Renzhe Zhang, Long Jiang, Tao Liu，Investigation on the temperature effect of a mixed vesicle composed of polydiacetylene and BODIPY 558，Colloids and Surfaces B: Biointerfaces 2007, 60, 41–45. 邓洁丽，郭彩欣，鲁闻生，刘涛，江龙，联乙炔囊泡一种基于分子组装的生物分子识别器件，化学进展, 2006, 18, 1397-1408. Caixin Guo, Paul Boullanger, Tao Liu, Long Jiang, Size Effect of Polydiacetylene Vesicles Functionalized with Glycolipids on Their Colorimetric Detection Ability, J. Phys. Chem. B 2005, 109, 18765-18771. Caixin Guo, Minhua Cao, Changwen Hu, Synthesis and Characterization of Dy(OH)3 and Dy2O3 Nanotubes, J. Nanosci. Nanotech. 5, (2005), 184-187 Caixin Guo, Minhua Cao, Changwen Hu, A Novel and Low-temperature Hydrothermal Synthesis of SnO2 Nanorods, Inorg. Chem. Commun. 7, (2004), 929-931. Minhua Cao, Caixin Guo, Yanjuan Qi, Changwen Hu, Enbo Wang, Shape and Size Control of ZnO Nanostructures via a Simple Solution Route, J. Nanosci. Nanotech. 4, (2004), 829-832. Minhua Cao, Yonghui Wang, Caixin Guo, Yanjuan Qi, Changwen Hu, Enbo Wang, A simple route towards CuO nanowires and nanorods, J. Nanosci. Nanotech. 2004, 4 (7), 824-828. Minhua Cao, Yonghui Wang, Caixin Guo, Yanjuan Qi, Changwen Hu, Preparation of ultrahigh-aspect-ratio hydroxyapatite nanofibers in reverse micelles under hydrothermal conditions, Langmuir, 2004, 20, 4784-4786. Danfeng Li, Changzhi Gu, Caixin Guo, Changwen Hu, The effects of ambient gases on the surface resistance of polyoxometalate/TiO2 film, Chem. Phys. Lett., 2004, 385 (1-2), 55-59. Yonghui Wang, Caixin Guo, Y. W. Chen, Changwen Hu, W. H. Yu, Self-assembled Multilayer Films Based on a Keggin-type Polyoxometalate and Polyaniline, J. Colloid and Interface Science, 264, (2003), 176.