当前位置: X-MOL首页全球导师 国内导师 › 陆刚

个人简介

2018.9-至今 山东大学,化学与化工学院,教授 2014.9-2018.8 美国匹兹堡大学,博士后,合作导师:Prof. Peng Liu 2012.8-2014.8 中科院福建物质结构研究所,助理研究员,合作导师:郭国聪 研究员 2008.9-2012.7 中国科学院大学,博士,导师:汪志祥 教授 2005.9-2008.7 西北农林科技大学,硕士 2001.9-2005.7 西北农林科技大学,学士

研究领域

理论与计算有机化学:利用计算化学的手段研究有机反应如何发生,以及如何改进。课题组将针对过渡金属催化有机反应中的若干核心问题开展理论计算研究。同时,我们将积极与实验化学家开展合作,协同攻克合成有机化学中极具挑战的难题。 总体研究思路:化学模型 → 反应规律 → 理解和预测。通过建立合理的化学模型来理解目标反应活性和选择性的根源,探索催化剂、底物、添加剂等因素影响反应的一般规律,最终达到预测和调控反应结果的目的。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Zhang, X.; Lu, G.; Sun, M.; Mahankali, M.; Ma, Y.; Zhang, M.; Hua, W.; Hu, Y.; Wang, Q.; Chen, J.; He, G.*; Qi, X.*; Shen, W.*; Liu, P.*; Chen, G.* “A General Strategy for Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular sp3 C−H Arylation”, Nat. Chem. 2018, 10, 540-548. Lv, X.; Huang, F.; Wu, Y.-B.; Lu, G.* “Origin of ligand effects on reactivities of pincer-Pd catalyzed hydrocarboxylation of allenes and alkenes with formate salts: a computational study”, Catal. Sci. Technol.2018, 8, 2835-2840. Lu, G.; Shao, H.;Omer, H.; Liu, P.* “Issues Particular to Organometallic Reactions” in “Applied Theoretical Organic Chemistry”, Ed. Tantillo, D., World Scientific, 2018. (book chapter) Lv, X.; Wu, Y.-B.; Lu, G.* “Computational exploration of ligand effects in copper-catalyzed boracarboxylation of styrene with CO2”, Catal. Sci. Technol. 2017, 7, 5049-5054. (Hot Article) O’Duill, M.; Matsuura, R.;Wang, Y.; Turnbull, J.; Gurak, J.; Gao, D.; Lu, G.; Liu, P.*; Engle, K.* “Tridentate Directing Groups Stabilize 6-Membered Palladacycles in Catalytic Alkene Hydrofunctionalization”,J. Am. Chem. Soc. 2017, 139, 15576-15579. Lu, G.; Yang Y.; Liu, R. Y.; Fang, C.; Lambrecht, D. S.*; Buchwald, S. L.*; Liu, P.* “Ligand-Substrate Dispersion Facilitates the Copper-Catalyzed Hydroamination of Unactivated Olefins”, J. Am. Chem. Soc. 2017,139, 16548-16555. (Top 20 most read JACS papers in November, 2017.) Burrows, L. C.; Jesikiewicz, L. T.; Lu, G.; Geib, S. J.; Liu, P.*; Brummond, K. M.* “Computationally-Guided Catalyst Design in the Type I Dynamic Kinetic Asymmetric Pauson−Khand Reaction of Allenyl Acetates”, J. Am. Chem. Soc. 2017, 139, 15022-15032. Wang, H.; Lu, G.; Sormunen, G. J.; Malik, H. A.; Liu, P.*; Montgomery, J.* “NHC Ligands Tailored for Simultaneous Regio- and Enantiocontrol in Nickel-Catalyzed Reductive Couplings”, J. Am. Chem. Soc. 2017,139, 9317-9324. Lv, X.; Lu, G.*; Wang, Z.-Q.; Xu, Z.-N.*; Guo, G.-C.* “Computational Evidence for Lewis Base-Promoted CO2 Hydrogenation to Formic Acid on Gold Surfaces”, ACS Catal. 2017, 7, 4519-4526. Lv, X.; Zhang, L.; Sun, B.; Li, Z.; Wu, Y.-B.; Lu, G.* “Computational Studies of Rh-Catalyzed Carboxylation of the C(sp2)–H Bond Using CO2”, Catal. Sci. Technol. 2017, 7, 3539-3545. Xia, Y.; Lu, G.; Liu, P.*; Dong, G.* “Catalytic Activation of Carbon–Carbon Bonds in Cyclopentanones”,Nature 2016, 539, 546-550. He, G.*; Lu, G.; Guo, Z.; Liu, P.*; Chen, G.* “Benzazetidine Synthesis via Palladium-Catalyzed Intramolecular C−H Amination”, Nat. Chem. 2016, 8, 1131-1136. Yang, Y.; Perry, I. B.; Lu, G.; Liu, P.*; Buchwald, S. L.* “Copper-Catalyzed Asymmetric Addition of Olefin-Derived Nucleophiles to Ketones”, Science 2016, 353, 144-150. Kennedy, N.*; Lu, G.; Liu, P.*; Cohen, T.* “Reductive Lithiation in the Absence of Aromatic Electron Carriers. A Steric Effect Manifested on the Surface of Lithium Metal Leads to a Difference in Relative Reactivity Depending on Whether the Aromatic Electron Carrier Is Present or Absent”, J. Org. Chem. 2015, 80, 8571-8582. Lu, G.; Fang, C.; Xu, T.; Dong, G.; Liu, P.*“Computational Study of Rh-Catalyzed Carboacylation of Olefins: Ligand-Promoted Rhodacycle Isomerization Enables Regioselective C–C Bond Functionalization of Benzocyclobutenones”, J. Am. Chem. Soc. 2015, 137, 8274-8283. Engle, K. M.; Lu, G.; Luo, S.-X.; Henling, L. M.;Takase, M. K.; Liu, P.*; Houk, K. N.*; Grubbs, R. H.* “Origins of Initiation Rate Differences in Ruthenium Olefin Metathesis Catalysts Containing Chelating Benzylidenes”, J. Am. Chem. Soc. 2015, 137, 5782-5792. Lu, G.; Zhang, P.; Sun, D.; Wang, L.; Zhou, K.; Wang, Z.-X.*; Guo, G.-C.* “Gold Catalyzed Hydrogenations of Small Imines and Nitrites: Enhanced Reactivity of Au Surface Toward H2 via Collaboration with a Lewis Base”, Chem. Sci. 2014, 5, 1082-1090. Chen, Z.-W.; Lu, G.; Li, P.-X.; Lin, R.-G.; Cai, L.-Z.; Wang, M.-S.*; Guo, G.-C.* “Influence of Supramolecular Interactions on Electron-Transfer Photochromism of the Crystalline Adducts of 4,4'-Bipyridineand Carboxylic Acids”, Cryst. Growth Des. 2014, 14, 2527-2531. Wang, L.; Lu, G.; Yang, D.; Wang, J.; Zhu, Z.;Wang, Z.*; Zhou, K.* “Manipulation of the Reducibility of Ceria-Supported Au Catalysts by Interface Engineering”, Chematchem 2013, 5,1308-1312. Zhao, L.; Huang, F.; Lu, G.; Wang, Z.-X.*; Schleyer, P. v.R.* “Why the Mechanisms of Digermyne and Distannyne Reactions with H2 Differ So Greatly”, J. Am. Chem. Soc. 2012, 134, 8856-8868.

推荐链接
down
wechat
bug