个人简介
教育背景
2009-09--2014-08 麻省理工学院 博士
2005-09--2009-06 中国科学技术大学 学士
工作简历
2018-04~2023-06,中国科学院深圳先进技术研究院, 研究员
2015-01~2018-03,加州大学洛杉矶分校, 博士后
研究领域
实验室利用合成生物学的工具,对微生物组的结构和功能进行理性设计和精准调控,致力于解决人体健康、农业生产等重大问题。
近期论文
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(1) Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design, Science, 2018, 第 6 作者
(2) Effects of mutations on replicative fitness and MHC-I binding affinity are among the determinants underlying CTL escape of HIV-1 Gag Epitopes, mBio, 2017, 第 1 作者
(3) Quantifying perinatal transmission of Hepatitis B viral quasispecies by tag linkage deep sequencing, Scientific Reports, 2017, 第 10 作者
(4) Comparative analysis of protein evolution in the genome of pre-epidemic and epidemic Zika virus, Infection, Genetics and Evolution, 2017, 第 2 作者
(5) Direct observation of increasing recovery length before collapse of a marine benthic ecosystem, Nature Ecology and Evolution, 2017, 第 3 作者
(6) Adaptation in protein fitness landscapes is facilitated by indirect paths, eLife, 2016, 第 1 作者
(7) Relation between stability and resilience determines the performance of early warning signals under different environmental drivers, Proceedings of the National Academy of Sciences, 2015, 第 1 作者
(8) Dynamics of a producer-freeloader ecosystem on the brink of collapse, Nature Communications, 2014, 第 3 作者
(9) Slower recovery in space before collapse of connected populations, Nature, 2013, 第 1 作者