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Pritchard, L., Broadhurst, D., (2014), On the statistics of identifying candidate pathogen effectors. Plant-Pathogen Interactions: Methods and Protocols, 1127(22), 53-64, New York, DOI: 10.1007/978-1-62703-986-4_4. Landi, A., Broadhurst, D., Vernon, S., Tyrrell, DL., Houghton, M., (2016), Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome. Cytokine, 78(2016), 27-36, DOI: 10.1016/j.cyto.2015.11.018. Chan, A., Mercier, P., Schiller, D., Bailey, R., Robbins, S., Eurich, D., Sawyer, M., Broadhurst, D., (2016), 1H-NMR urinary metabolomic profiling for diagnosis of gastric cancer. British Journal of Cancer, 114(1), 59-62, London, UK, DOI: 10.1038/bjc.2015.414. Hollywood, K., Winder, C., Dunn, W., Xu, Y., Broadhurst, D., Griffiths, C., Goodacre, R., (2015), Exploring the mode of action of dithranol therapy for psoriasis: A metabolomic analysis using HaCaTcells. Molecular Biosystems, 11(8), 2198-2209, Cambridge, United Kingdom, DOI: 10.1039/c4mb00739e. Balikcioglu, P., Balikcioglu, M., Muehlbauer, M., Purnell , J., Broadhurst, D., Freemark, M., Haqq, A., (2015), Macronutrient regulation of ghrelin and peptide YY in pediatric obesity and prader-willi syndrome. Journal of Clinical Endocrinology and Metabolism, 100(10), 3822-3831, Chevy Chase, Maryland, United States, DOI: 10.1210/jc.2015-2503. Murphy, N., Broadhurst, D., Khashan, A., Gilligan, O., Kenny, L., Donoghue, K., (2015), Gestation-specific D-dimer reference ranges: a cross-sectional study. BJOG: an International Journal of Obstetrics and Gynaecology, 122(3), 395-400, Chichester, United Kingdom, DOI: 10.1111/1471-0528.12855. Denihan, N., Walsh, B., Reinke, S., Sykes, BD., Mandal, R., Wishart, D., Broadhurst, D., Boylan, G., Murray, D., (2015), The effect of haemolysis on the metabolomic profile of umbilical cord blood. Clinical Biochemistry, 48(7-8), 534-537, Philadelphia, United States, DOI: 10.1016/j.clinbiochem.2015.02.004. Dunn, W., Lin, W., Broadhurst, D., Begley, P., Brown, M., Zelena, E., Vaughan, A., Halsall, A., Harding, N., Knowles, J., Francis-McIntyre, S., Tseng, A., Ellis, D., O'Hagan, S., Aarons, G., Benjamin , B., Chew-Graham, S., Moseley, C., Potter, P., Winder, C., Potts, C., Thornton, P., McWhirter, C., Zubair, M., Pan, M., Burns, A., Cruickshank, J., Jayson, G., Purandare, N., Wu, F., Finn, J., Haselden, J., Nicholls, A., Wilson, I., Goodacre, R., Kell, D., (2015), Molecular phenotyping of a UK population: defining the human serum metabolome. Metabolomics, 11(1), 9-26, New York, United States, DOI: 10.1007/s11306-014-0707-1. Stanley, J., Sulek, K., Andersson, I., Davidge, S., Kenny, L., Sibley, C., Mandal , R., Wishart, D., Broadhurst, D., Baker, P., (2015), Sildenafil therapy normalizes the aberrant metabolomic profile in the comt -/- mouse model of preeclampsia/fetal growth restriction. Scientific Reports, 5(15 December), ART 18241, London, United Kingdom, DOI: 10.1038/srep18241. Walsh, J., Reinke, S., Mamik, M., McKenzie, B., Maingat, F., Branton, W., Broadhurst, D., Power, C., (2014), Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS. Retrovirology, 11(N/A), 35, DOI: 10.1186/1742-4690-11-35.. Anderson, S., Dunn, W., Banerjee, M., Brown, M., Broadhurst, D., Goodacre, R., Cooper, G., Kell, D., Cruickshank, JK., (2014), Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes. PLoS One, 9(9), e103217, DOI: 10.1371/journal.pone.0103217. Kirwan , J., Weber, R., Broadhurst, D., Viant, M., (2014), Direct infusion mass spectrometry metabolomics dataset: A benchmark for data processing and quality control. Scientific Data, 1(10 June 2014), Article No.140012, DOI: 10.1038/sdata.2014.12. Reinke, S., Broadhurst, D., Sykes , B., Baker, G., Catz, I., Warren, K., Power, C., (2014), Metabolomic profiling in multiple sclerosis: insights into biomarkers and pathogenesis. Multiple Sclerosis Journal, 20(10), 1396-1400, DOI: 10.1177/1352458513516528. Reinke, S., Walsh, B., Boylan, G., Sykes, B., Kenny, L., Murray, D., Broadhurst, D., (2013), 1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: Implications for hypoxic ischemic encephalopathy. Journal of Proteome Research, 12(9), 4230-4239, Washington, USA, DOI: 10.1021/pr400617m. Xia, J., Broadhurst, D., Wilson, M., Wishart, D., (2013), Translational biomarker discovery in clinical metabolomics: An introductory tutorial. Metabolomics, 9(2), 280-299, New York, USA, DOI: 10.1007/s11306-012-0482-9. Kirwan, J., Broadhurst, D., Davidson, R., Viant, M., (2013), Characterising and correcting batch variation in an automated direct infusion mass spectrometry (DIMS) metabolomics workflow. Analytical and Bioanalytical Chemistry, 405(15), 5147-5157, Heidelberg, Germany, DOI: 10.1007/s00216-013-6856-7. Xia, J., Mandal, R., Sinelnikov, I., Broadhurst, D., Wishart, D., (2012), MetaboAnalyst 2.0-a comprehensive server for metabolomic data analysis. Nucleic Acids Research, 40(W1), W127-W133, Oxford, UK, DOI: 10.1093/nar/gks374. Bartels, A., Egan, N., Broadhurst, D., Khashan, A., Joyce, C., Stapleton, M., O'Mullane, J., O'Donoghue, K., (2012), Maternal serum cholesterol levels are elevated from the 1st trimester of pregnancy: A cross-sectional study. Journal of Obstetrics and Gynaecology, 32(8), 747-752, DOI: 10.3109/01443615.2012.714017. Dunn, W., Wilson, I., Nicholls, A., Broadhurst, D., (2012), The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans. Bioanalysis, 4(18), 2249-2264, London, UK, DOI: 10.4155/bio.12.204. Walsh, B., Broadhurst, D., Rupasri, M., Wishart, D., Boylan, G., Kenny, L., Murray, D., (2012), The metabolomic profile of umbilical cord blood in neonatal hypoxic ischaemic encephalopathy. PLoS One, 7(12), Article No. e50520, DOI: 10.1371/journal.pone.0050520. Reyes, L., Garcia, R., Ruiz, S., Broadhurst, D., Aroca, G., Davidge, S., Lopez-Jaramillo, P., (2012), Angiogenic imbalance and plasma lipid alterations in women with preeclampsia from a developing country. Growth Factors, 30(3), 158-166, Oxfortshire, UK, DOI: 10.3109/08977194.2012.674035.

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