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个人简介

2006.9-2010.6 四川大学化学学院化学专业,学士 2010.9-2015.6 四川大学化学学院有机化学专业,博士(导师:冯小明教授) 2015.9-2018.2 新加坡南洋理工大学,博士后(导师: Choon-Hong Tan教授) 2018.4-2021.8 四川大学化学学院 副教授 2021.9-至今 四川大学化学学院 教授

研究领域

不对称催化、光催化、自由基化学、有机硅化学、手性药物和生物活性化合物的合成

近期论文

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Lili Feng, Xiaofan Chen, Ning Guo, Yuqiao Zhou, Lili Lin, Weidi Cao,* Xiaoming Feng,* Visible-Light-Induced Chemo-, Diastereo- and Enantioselective α-C(sp3)−H Functionalization of Alkyl Silanes, Chem. Sci. 2023, 14, 4516−4522. Xinpeng Sang, Yuhao Mo, Shiya Li, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Bimetallic Tandem Catalysis-Enabled Enantioselective Cycloisomerization/Carbonyl–ene Reaction for Construction of 5-Oxazoylmethyl a-Silyl Alcohol, Chem. Sci. 2023, 14, 8315−8320. Ning Guo, Yao Luo, Lili Feng, Zhili Liu, Weidi Cao,* Xiaoming Feng,* Radical Conjugate Addition of Acylsilane Enabled by Synergistic Photoredox and Lewis Acid Catalysis, Asian J. Org. Chem. 2023, 12, e202300164. Qianchi Lin, Siyuan Wang, Rui Weng, Weidi Cao,* Xiaoming Feng,* Chiral Lewis Acid-Catalyzed Asymmetric Multicomponent Michael Reaction through [1,2]-Phospha-Brook Rearrangement, Org. Lett. 2023, 25, 6262−6266. Wanlong Xiao, Fang Li, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Synthesis of Axially and Centrally Chiral 1,2-Dihydrobenzofuro[3,2-b]pyridines through a [2+2] Cycloaddition/Retroelectrocyclization/Re-Cycloaddition Cascade, Org. Lett. 2023, 25, 8005–8009. Fengcai Zhang, Yuqiao Zhou, Hansen Zhao, Long Chen, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric [3 + 2] Cycloaddition of Exocyclic Enol Ethers for the Synthesis of Spiroketals, Precis. Chem. 2023, 1, 423–428. Liuzhen Hou, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Recent Advances in Visible Light-induced Asymmetric Transformations of Carbonyl Compounds into Chiral Alcohols, ChemCatChem 2023, 15, e202300893. Weidi Cao, Xiaohua Liu,* Recent Advances on Catalytic Enantioselective Protonation for Construction of α-Tertiary Carbonyl Compounds, Chin. J. Org. Chem. 2023, 43, 961–973. Liuzhen Hou, Yuqiao Zhou, Han Yu, Tangyu Zhan, Weidi Cao,* Xiaoming Feng,* Enantioselective Radical Addition to Ketones through Lewis Acid-Enabled Photoredox Catalysis, J. Am. Chem. Soc. 2022, 144, 22140−22149. (Most Read Articles, highlighted by Synfacts) Guihua Pan, Changli He, Min Chen, Qian Xiong, Weidi Cao,* Xiaoming Feng,* Synthesis of Dihydroisoquinoline and Dihydropyridine Derivatives via Asymmetric Dearomative Three-component Reaction, CCS Chem. 2022, 4, 2000−2008. Liangkun Yang, Wang-Yuren Li, Liuzhen Hou, Tangyu Zhan, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* NickelⅡ-catalyzed Asymmetric Photoenolization/Mannich Reaction of (2-Alkylphenyl) Ketones, Chem. Sci. 2022, 13, 8576–8582. Fengcai Zhang, Xinpeng Sang, Yuqiao Zhou, Weidi Cao,* Xiaoming Feng,* Enantioselective Synthesis of Azetidines through [3 + 1]-Cycloaddition of Donor−Acceptor Aziridines with Isocyanides, Org. Lett. 2022, 24, 1513−1517. (Highlighted by Org. Chem. Highlights) Changqiang He, Zhikun Wu, Yuqiao Zhou, Weidi Cao,* Xiaoming Feng,* Asymmetric Catalytic Nitrooxylation and Azidation of β-Keto Amides/esters with Hypervalent Iodine Reagents, Org. Chem. Front. 2022, 9, 703−708. Li Dai, Wen Liu, Yuqiao Zhou, Zi Zeng, Xinyue Hu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Halogenation/Semipinacol Rearrangement of 3-Hydroxyl-3-vinyl Oxindoles: A Stereodivergent Kinetic Resolution Process, Angew. Chem. Int. Ed. 2021, 60, 26599–26603. Mingming Guan, Shiyu Wang, Yao Luo, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Catalytic Asymmetric Addition of Thiols to Silyl Glyoxylates for Synthesis of Multi-hetero-atom Substituted Carbon Stereocenter, Chem. Sci. 2021, 12, 7498–7503. Mingyi Jiang, Kaiqi Hu, Yuqiao Zhou, Qian Xiong, Weidi Cao,* Xiaoming Feng,* Enantioselective Isocyanide-based Multicomponent Reaction with Alkylidene Malonates and Phenols, Org. Lett. 2021, 23, 5261–5265. Weidi Cao, Xiaohua Liu,* Asymmetric Formal Hetero-Ene Reaction of Allylgold Intermediates, Chin. J. Org. Chem. 2021, 41, 857−858. Ziwei Zhong, Zhijie Xiao, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Synthesis of 3,2'-Pyrrolinyl Spirooxindoles via Conjugate Addition/Schmidt-type Rearrangement of Vinyl Azides and (E)-Alkenyloxindoles, Chem. Sci. 2020, 11, 11492−11497. Liuzhen Hou, Tengfei Kang, Liangkun Yang, Weidi Cao,* Xiaoming Feng,* Enantioselective Imino-Ene Reaction of N-Sulfonyl Ketimines with Silyl Enol Ethers: Access to Chiral Benzosultams, Org. Lett. 2020, 22, 1390−1395. Yu Zhang, Hao Pan, Wen Liu, Weidi Cao,* Xiaoming Feng,*Asymmetric Catalytic Synthesis of Epoxides via Three-Component Reaction of Diazoacetates, 2‑Oxo-3-ynoates, and Nitrosoarenes, Org. Lett. 2020, 22, 6744−6749. Xiangqiang Li, Mingyi Jiang, Tangyu Zhan, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Three-component Hydroacyloxylation/1,4-Conjugate Addition of Ynamides, Chem Asian J. 2020, 15, 1953−1956. Weidi Cao, Xiaohua Liu, Xiaoming Feng,* Chiral N,Nʹ-dioxide and Their Metal Complexes in Asymmetric Catalysis (in Chinese), Chin. Sci. Bull. 2020, 65, 2941−2951. Bin Shen, Wen Liu, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Asymmetric Synthesis of α,β-Epoxy-γ-lactams through Tandem Darzens/Hemiaminalization Reaction, Org. Lett. 2019, 21, 4713−4716. Yan Wang, Kaixuan Wang, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Diastereo- and Enantioselective 1,6-Conjugate Addition of 2‑Azaarylacetamides to para-Quinone Methides, Org. Lett. 2019, 21, 6063−6067. Weidi Cao, Xiaoming Feng, Xiaohua Liu,* Reversal of Enantioselectivity in Chiral Metal Complex-catalyzed Asymmetric Reactions, Org. Biomol. Chem. 2019, 17, 6538−6550. Wen Liu, Weidi Cao,* Haipeng Hu, Lili Lin, Xiaoming Feng,* Dynamic Kinetic Asymmetric Transformations of β-Halo-α-Keto Esters by N,N′-Dioxide/Ni(II)-Catalyzed Carbonyl-Ene Reaction, Chem. Commun. 2018, 54, 8901−8904. (highlighted by Synfacts) Hang Zhang, Qian Yao, Weidi Cao,* Shulin Ge, Jinxiu Xu, Xiaohua Liu and Xiaoming Feng,* Catalytic Enantioselective Ene-type Reactions of Vinylogous Hydrazone: Construction of α-Methylene-g-butyrolactone Derivatives, Chem. Commun. 2018, 54, 12511–12514. Lifeng Wang, Weidi Cao,* Hongjiang Mei, Linfeng Hu, Xiaoming Feng,* Catalytic Asymmetric Synthesis of Chiral Spiro-Cyclopropyl Oxindoles from 3-Alkenyl-Oxindoles and Sulfoxonium Ylides, Adv. Synth. Catal. 2018, 360, 4089-4093. (VIP) Changqiang He, Weidi Cao,* Jianlin Zhang, Shulin Ge, Xiaoming Feng,* Chirall N,N'-Dioxide/Scandium(III)-Catalyzed Asymmetric Alkylation of N-Unprotected 3-Substituted Oxindoles, Adv. Synth. Catal. 2018, 360, 4301-4305. (highlighted by Synfacts) Weidi Cao, Xiaohua Liu,* Xiaoming Feng, Chiral Organobases: Properties and Applications in Asymmetric Catalysis, Chin. Chem. Lett. 2018, 29, 1201−1208. Weidi Cao, Davin Tan, Richmond Lee,* Choon-Hong Tan,* Enantioselective 1,2-Anionotropic Rearrangement of Acylsilane through a Bisguanidinium Silicate Ion Pair, J. Am. Chem. Soc. 2018, 140, 1952−1955.

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