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Huiling Xu,Guangwei Han,Ying Lu,Zehui Liu,Lina Tao,He Fang*.(2021)Broad neutralization of CSFV with novel monoclonal antibodies in vivo.Int J Biol Macromol.2021 Jan 23;173:513-523.doi:10.1016/j.ijbiomac.2021.01.142.(IF5=5.137)
Xu HL,Liu Ze-Hui.,Zheng Suya,Han Guangwei.,He Fang*.(2020).CD163 Antibodies Inhibit PRRSV Infection via Receptor Blocking and Transcription Suppression.Vaccines(Basel).2020 8(4),592;https://doi.org/10.3390/vaccines8040592(IF4.105)
Tao LN,Liu ZH,Xu HL,Lu Y,Liao M,He Fang*.(2020).LvYY1 Activates WSSV ie1 Promoter for Enhanced Vaccine Production and Efficacy.Vaccines(Basel).2020 Sep 8;8(3):E510.doi:10.3390/vaccines8030510.PMID:32911686(IF4.105)
Han Guangwei.,Xu Huiling.,Wang Yanli.,Liu Zehui.,He Fang*.(2020).Efficacy Evaluation of Two Commercial Vaccines Against a Recombinant PRRSV2 Strain ZJnb16-2 From Lineage 8 and 3 in China.Pathogens,9(1),(IF3.405)doi:10.3390/pathogens9010059
Xu H,Wang Y,Han G,Fang W,He Fang*.(2020)Identification of E2 with improved secretion and immunogenicity against CSFV in piglets.BMCMicrobiol.2020;20(1):26.Published2020Feb4.(IF3.287)doi:10.1186/s12866-020-1713-2
Han Guangwei.,Lei Kaixia.,Xu Huiling.,He Fang*.(2020).Genetic characterization of a novel recombinant PRRSV2 from lineage 8,1 and 3 in China with significant variation in replication efficiency and cytopathic effects.Transbound Emerg Dis,2020 Jul;67(4):1574-1584.doi:10.1111/tbed.13491.Epub 2020 Feb 5..(IF4.188)doi:10.1111/tbed.13491
Liu Ze-Hui.,Lei Kai-Xia.,Han Guang-Wei.,Xu Hui-Ling.,He Fang*.(2020).Novel Lentivirus-Based Method for Rapid Selection of Inhibitory Nanobody against PRRSV.Viruses,12(2)(IF 3.811)doi:10.3390/v12020229
Han Guangwei.,Xu Huiling,Wang Kexiong,He Fang*.(2019).Emergence of Two different recombinant PRRSV strains with low neutralizing antibody susceptibility in China.Sci Rep,9(1),2490.(IF4.011)doi:10.1038/s41598-019-39059-8
Li Liang.,etc.,He Fang.,Kwong Chow Vincent Tak.,Tan Nguan Soon.(2019).Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia.mBio,10(3),undefined.(IF6.747)doi:10.1128/mBio.02469-18
Pierce Carrie L.,Williams Tracie L.,Santana Wanda I.,Levine Marnie.,Chen Li-Mei.,Cooper Hans C.,Solano Maria I.,Woolfitt Adrian R.,Marasco Wayne A.,Fang He.,Donis Ruben O.,Barr John R.(2017).Immunocapture isotope dilution mass spectrometry in response to a pandemic influenza threat.Vaccine,35(37),5011-5018.(IF3.269)doi:10.1016/j.vaccine.2017.07.049
Jia Q,Ng Q,Chin W,Meng T,Chow VTK,Wang CI,Kwang J,He F*.Effective in vivo therapeutic IgG antibody against VP3 of enterovirus 71 with receptor-competing activity.Sci Rep.2017 Apr 19;7:46402.doi:10.1038/srep46402.
He Fang*.,Leyrer Sonja.,Kwang Jimmy.(2016).Strategies towards universal pandemic influenza vaccines.Expert Rev Vaccines,15(2),215-25.（IF4.531)doi:10.1586/14760584.2016.1115352
Ng Qingyong.,He Fang*,Kwang Jimmy*.(2015).Recent Progress towards Novel EV71 Anti-Therapeutics and Vaccines.Viruses,7(12),6441-57.(IF3.811)doi:10.3390/v7122949
Tan Y,He Fang*and Kwang J.*(2015)How can we develop universal H5N1 vaccines Immunotherapy 2015 Aug 7:1-4
P.Rai,M.Parrish,I.J.J.Tay,L.Na,S.Ackerman,He F.,J Kwang,V.T.K.Chow and B.P.Engelward.(2015)Streptococcus pneumoniae Secretes Hydrogen Peroxide Leading to DNA Damage and Apoptosis in Lung Cells.PNAS 112(26):E342130
Rai P,He F,Kwang J,Engelward BP,Chow VT.Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle Arrest.Sci Rep.2016 Mar 30;6:22972.doi:10.1038/srep22972.
Kumar SR,Prabakaran M,K.V.Ashok Raj,He F.and J.Kwang(2015)Amino acid Substitutions Improve the Immunogenicity of H7N7HA Protein and Protect Mice against Lethal H7N7 Viral Challenge PLoS One 10(6):e0128940
Tan Y,Ng QY,Jia Q,Kwang J and He Fang*.(2015)A novel humanized antibody neutralizes H5N1 via two different mechanisms..J Virol 89(7):3712-22
He,F.,Prabakaran M,Kumar SR,Tan Y,Kwang J.(2014)Monovalent H5 vaccine based on epitope-chimeric HA provides broad cross-clade protection against variant H5N1 viruses in mice.Antiviral Research.105:143-151.
Prabakaran,M.,Leyrer S.,He F.,Auer S.,S.R Kumar,Kindsmueller K.,Mytle N.,Schneider J.,Lockhart S.,Kwang J..(2014)Progress Toward A Universal H5N1 Vaccine:A Recombinant Modified Vaccina Virus Ankara-expressing Trivalent Hemagglutinin Vaccine.PLoS ONE 17;9(9):e107316.
Prabakaran,M.,S.Rajesh Kumar,K.V.Ashok Raj,X.Wu,He F..,J.Zhou,and J.Kwang.(2014).Cross-protective efficacy of baculovirus displayed hemagglutinin against highly pathogenic influenza H7 subtypes.Antiviral Res 109C:149-159.
He,F.,Prabakaran M,Tan Y,Indira K,Kumar SR,Kwang J.(2013)Development of dual-function ELISA for effective antigen and antibody detection against H7 avian influenza virus.BMC Microbiol.2013 Oct 2;13(1):219.
He,F.,S.R.Kumar,et al.(2013)Effective intranasal therapeutics and prophylactics with monoclonal antibody against lethal infection of H7N7 influenza virus.Antiviral Research.100(1):207-14
He,F and Kwang J.(2013)Monoclonal antibody targeting neutralizing epitope on H5N1 influenza virus of clade 1 and 0 for specific H5 quantification.Influenza Research and Treatment 2013;2013:360675.doi:10.1155/2013/360675.
He,F.,T.K.Kiener,et al.(2013).Development of a sensitive and specific epitope-blocking ELISA for universal detection of antibodies to human enterovirus 71 strains.PLoS One 8(1):e55517.
Prabakaran,M.,A.B.Kolpe,He,F.,et al.(2013).Cross-protective efficacy of bivalent recombinant baculoviral vaccine against heterologous influenza H5N1 challenge.Vaccine 31(10):1385-1392.
Chen,Q.,He F.,et al.(2012).GM-CSF and IL-4 stimulate antibody responses in humanized mice by promoting T,B,and dendritic cell maturation.J Immunol 189(11):5223-5229.
Kiener TK,Jia Q,Lim XF,He F,Meng T,et al.(2012)Characterization and specificity of the linear epitope of the enterovirus 71 VP2 protein.Virol J 9:55.
He,F and Kwang J.(2011)Universal Recognition and Vaccination of H5N1 Hemagglutinin.Asia Pacific Biotech News 15(11),19-22
Velumani S,Ho HT,He F,Musthaq S,Prabakaran M,et al.(2011)A novel peptide ELISA for universal detection of antibodies to human H5N1 influenza viruses.PLoS One 6:e20737.
Prabakaran M,Meng T,He F,Yunrui T,Qiang J,et al.(2011)Subcutaneous immunization with baculovirus surface-displayed hemagglutinin of pandemic H1N1 Influenza A virus induces protective immunity in mice.Clin Vaccine Immunol 18:1582-1585.
He,F.,Retno,D S.,Sri,M.,Goutama,M.and Kwang,J.(2010).Complementary monoclonal antibody-based dot ELISA for universal detection of H5 avian influenza virus.BMC Microbiol 10,330
Prabakaran,M,He F,T Meng,S Madhan,Y Tan,Q Jia and J Kwang.2010.Neutralizing Epitopes of Influenza Virus Hemagglutinin:Target for the Development of a Universal Vaccine against H5N1 Lineages.J Virol 84:11822-11830.
Chua,TH,CYH Leung,He F,CK Chow,SK Ma,SF Sia,IHY Ng,SG Fenwick,CM James,SB Chua,ST Chew,J Kwang,JSM Peiris and TM Ellis.2010.Evaluation of a Subunit H5 Vaccine and an Inactivated H5N2 Avian Influenza Marker Vaccine in Ducks Challenged with Vietnamese H5N1 Highly Pathogenic Avian Influenza Virus.Influenza Research and Treatment 2010,Article ID 489213.
He,F.,Madhan,S.,and Kwang,J.(2009).Baculovirus vector as a delivery vehicle for influenza vaccines.Expert Rev Vaccines 8(4),455-67.
He,F.,Du,Q.,Ho,Y.,and Kwang,J.(2009).Immunohistochemical detection of Influenza virus infection in formalin-fixed tissues with anti-H5 monoclonal antibody recognizing FFWTILKP.J Virol Methods 155(1),25-33.
He,F.,Syed,S.M.,Hameed,A.S.,and Kwang,J.(2009).Viral ubiquitin ligase WSSV222 is required for efficient white spot syndrome virus(WSSV)replication in shrimp.J Gen Virol 90(pt6),1483-90.
Ho,H.T.,Qian,H.L.,He,F.,Meng,T.,Szyporta,M.,Prabhu,N.,Prabakaran,M.,Chan,K.P.,and Kwang,J.(2009).Rapid detection of H5N1 subtype influenza viruses by antigen capture enzyme-linked immunosorbent assay using H5-and N1-specific monoclonal antibodies.Clin Vaccine Immunol 16(5),726-32.
Prabhu,N.,Prabakaran,M.,He,F.,Qian,H.L.,Ho,H.T.,Jia,Q.and Kwang,J.(2009)Combination Therapy using Chimeric Monoclonal Antibodies Protects Mice from Lethal H5N1 Infection and Prevents formation of Escape Mutants.PLoS ONE 4(5),e5672.
Prabakaran,M.,Ho,H.T.,Prabhu,N.,Velumani,S.,Szyporta,M.,He,F.,Chan,K.P.,Chen,L.M.,Matsuoka,Y.,Donis,R.O.,and Kwang,J.(2009).Development of epitope-blocking ELISA for universal detection of antibodies to human H5N1 influenza viruses.PLoS ONE 4(2),e4566.
Prabhu,N,M Prabakaran,Qian HL,He F,H Ho,J Qiang,M Goutama,A P Lim,BJ Hanson and J Kwang.(2009)Prophylactic and therapeutic efficacy of a chimeric monoclonal antibody specific for H5 hemagglutinin against lethal H5N1 Influenza.Antiviral therapy,14:911-921.
He,F.,and Kwang,J.(2008).Identification and characterization of a new E3 ubiquitin ligase in white spot syndrome virus involved in virus latency.Virol J 5,151.
He,F.,Ho,Y.,Yu,L.,and Kwang,J.(2008).WSSV ie1 promoter is more efficient than CMV promoter to express H5 hemagglutinin from influenza virus in baculovirus as a chicken vaccine.BMC Microbiol 8,238.
Prabakaran,M.,Velumani,S.,He,F.,Karuppannan,A.K.,Geng,G.Y.,Yin,L.K.,and Kwang,J.(2008).Protective immunity against influenza H5N1 virus challenge in mice by intranasal co-administration of baculovirus surface-displayed HA and recombinant CTB as an adjuvant.Virology 380(2),412-20.
Liu,J.,Zhu,Y.,Chen,I.,Lau,J.,He,F.,Lau,A.,Wang,Z.,Karuppannan,A.K.,and Kwang,J.(2007).The ORF3 protein of porcine circovirus type 2 interacts with porcine ubiquitin E3 ligase Pirh2 and facilitates p53 expression in viral infection.J Virol 81(17),9560-7.
He,F.,Fenner,B.J.,Godwin,A.K.,and Kwang,J.(2006).White spot syndrome virus open reading frame 222 encodes a viral E3 ligase and mediates degradation of a host tumor suppressor via ubiquitination.J Virol 80(8),3884-92.
Wang,Z.,Chua,H.K.,Gusti,A.A.,He,F.,Fenner,B.,Manopo,I.,Wang,H.,and Kwang,J.(2005).RING-H2 protein WSSV249 from white spot syndrome virus sequesters a shrimp ubiquitin-conjugating enzyme,PvUbc,for viral pathogenesis.J Virol 79(14),8764-72.
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