黄耀伟 - 浙江大学 - 动物科学学院

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黄耀伟教授博士生导师收藏完善纠错
浙江大学动物科学学院
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个人简介

黄耀伟，男，博士，浙江大学动物科学学院动物医学系教授/博士生导师主要学术成果、奖项与学术兼职：迄今发表SCI收录论文81篇，总引用2050余次（根据ISI数据库），H指数27；其中第一作者及通讯作者（含共同通讯作者）论文34篇。已授权美国及欧亚拉美多国猪病毒疫苗相关专利6项（排名第一或第二）；中国授权专利4项。获浙江省人民政府科学技术奖一等奖2次（分别排名第2和第3）。SCI期刊Virology、Veterinary Microbiology编委（Editorial Board Member）、《中国兽医学报》编委。入选国家万人计划科技创新领军人才、科技部中青年科技创新领军人才、国家海外高层次青年人才计划、浙江省海外高层次人才引进计划特聘专家、浙江省151人才工程、杭州市“钱江特聘”专家。浙江省杰出青年基金获得者、中国畜牧兽医学会生物技术学分会常务理事、浙江省免疫学会常务理事。教育经历： 2000/09—2003/03，浙江大学，生物医学工程系，工学博士； 1998/09—2000/08，浙江大学，动物科学学院，攻读预防兽医学硕士（后转硕博连读）； 1994/09—1998/07，南京大学，生物科学与技术系，理学学士研究工作经历： 2013/09—浙江大学动物科学学院，教授 2011/01—2013/08，美国弗吉尼亚理工大学兽医学院生物医学与病理生物学系，研究助理教授(Research Assistant Professor) 2008/01—2010/12，美国弗吉尼亚理工大学兽医学院，研究科学家(Research Scientist) 2003/04—2007/12，美国弗吉尼亚理工大学兽医学院，博士后 ResearcherID网址：https://publons.com/researcher/1270749/yaowei-huang/ 欢迎报考2021年硕士、博士研究生and欢迎病毒学、分子生物学、预防兽医学方向博士毕业生应聘博士后：从2017年开始，浙大兽医学的博士入学不再采用考试，实行考生申请-导师考核制度。 2020年开始的海南浙江大学研究院硕士生专项计划（兽医专硕）：http://oc.zju.edu.cn/2020/0430/c30428a2092233/page.htm 对本实验室研究感兴趣的同学请与我联系教学与课程开设课程：本科生：《专业英语与信息检索》研究生：《兽医分子病理生物学》，《兽医生物医药专题》，《兽医科学进展》；曾授课：《预防兽医学专题》，《动物源性疫病控制与检疫》 MOOC课：主讲《动物疫病与人类健康》（通识课）中国大学MOOC网址：https://www.icourse163.org/course/ZJU-1206706822 新冠病毒科普与评论：教育部新闻办-微言教育《战“疫”公开课》：https://mp.weixin.qq.com/s/uNudQnyQtzbx6rVi_MJ_CA 世界野生动植物保护日宣传漫画：https://zj.zjol.com.cn/qihanghao/100645336.html 科普中国《这是病毒——给孩子讲病毒和新型冠状病毒》：https://v.qq.com/x/page/m3061togajh.html Opriessnig T,Huang YW.Further information on possible animal sources for human COVID-19.Xenotransplantation.2020,27:e12651. Opriessnig T,Huang YW.Update on possible animal sources for COVID-19 in humans.Xenotransplantation.2020,27:e12621. Opriessnig T,Huang YW.Coronavirus disease 2019(COVID-19)outbreak:Could pigs be vectors for human infections?Xenotransplantation.2020,27:e12591. Wu Y,Ho W,Huang Y,Jin DY,Li S,Liu SL,Liu X,Qiu J,Sang Y,Wang Q,Yuen KY,Zheng ZM.SARS-CoV-2 is an appropriate name for the new coronavirus.Lancet.2020,395(10228):949-950. 出版著作 Book Chapters: Meng XJ,Huang YW.2021.Circoviridae and Anelloviridae.In:Fields Virology,7th Edition(volume 2,chapter 7).David M.Knipe and Peter M.Howley(eds).Lippincott Williams&Wilkins,Philadelphia,PA.pp xxxx-xxxx.in press. 专利成果授权专利：麻疹病毒mRNA甲基转移酶缺陷减毒疫苗株及其应用（2021；CN108103097B）一种包含戊型肝炎病毒复制子的人肝癌细胞系、应用及构建方法（2020；CN109913424B）一种抗病毒多肽、编码基因、载体、宿主菌及应用（2020；CN107698665B）表达载体及其制备方法、PEDV-S1蛋白及包含该蛋白的间接ELISA检测试剂盒（2020；CN107664697B）研究项目 Research grants(as PI) 1.浙江省杰出青年基金（2014） 2.留学回国人员启动基金（2015） 3.国家自然科学基金面上项目（2016） 4.国家十三五重点研发计划（2016-2020） 5.浙江省重点研发计划（2016-2019） 6.海外横向委托课题（2015-2017） 7.国家十三五重点研发计划（2017-2020） 8.国家自然科学基金面上项目（2019-2022） 9.上市公司横向委托课题（2018-2022） 10.动物基因工程疫苗国家重点实验室开放课题（2019） 11.国家自然科学基金专项项目（2020）实验室消息 2014年11月：实验室PI黄耀伟博士获勃林格殷格翰“2014年度猪蓝耳病研究进步奖”。 2014年12月：实验室PI黄耀伟博士在芝加哥举行的北美蓝耳病大会上作PEDV研究的邀请报告。 http://www.ksvma.org/?Program http://www.ksvma.org/?Speakers 2015年6月：实验室PI黄耀伟博士加入兽医学科TOP SCI期刊Veterinary Microbiology的Editorial Advisory Board作为期刊编委。 http://www.journals.elsevier.com/veterinary-microbiology/editorial-board/ 2015年9月：在Genome Announcements杂志发表文章'Complete Genome Sequence of Porcine Deltacoronavirus Strain CH/Sichuan/S27/2012 from Mainland China'报道第一个猪丁型冠状病毒中国大陆毒株。 http://genomea.asm.org/content/3/5/e00945-15.abstract 2017年8月：覃盼参加第十二届全国病毒学学术研讨会获得“优秀墙报奖”（共5名）。http://www.sohu.com/a/161906991_749000 2017年9月：发现引起仔猪腹泻的新病原——一种新型的猪肠道甲型冠状病毒（SeACoV）。http://www.sciencedirect.com/science/article/pii/S0378113517309409 中文介绍：http://www.sohu.com/a/197584550_749000 2017年12月：实验室PI黄耀伟在芝加哥举行的北美蓝耳病大会上作新发冠状病毒SeACoV研究的邀请报告。 http://www.vet.k-state.edu/na-prrs/speakers.html http://www.vet.k-state.edu/na-prrs/program.html 2018年5月：与浙大医学院、俄亥俄州立大学兽医学院合作的改进麻疹疫苗文章被Virology杂志主编选为本期（5月）的研究亮点文章并推送到杂志官方博客Virology Highlights上。 https://www.journals.elsevier.com/virology/virology-highlights/improved-vaccine-candidates-for-measles-virus 论文链接：https://www.sciencedirect.com/science/article/pii/S0042682218300655 2018年8月10日：实验室PI黄耀伟在哈尔滨举行的中国畜牧兽医学会生物技术分会暨中国免疫学会兽医免疫分会第十三次学术研讨会作“新发猪肠道甲型冠状病毒的发现与特征鉴定”报告，并获优秀青年报告奖（共5名）。 http://www.hvri.ac.cn/html/zonghexinwen/suonaxinwen/2018/0813/1783.html 实验室团队成员我们的合照 2014年11月2020年6月实验室成员覃盼博士后王斌博士后史芳舒科研助理 2013级博士生2017级博士生2020级博士生吉春苗徐令东杨永乐 2015级直博生2015级硕博连读生2016级硕博连读生梁齐章梅小强赵壮壮 2018级博士生2018级博士生2019级博士生陈楚焦亚娟彭蕾 2019级直博生2020级博士生2018级硕士生苏权徐国晗李亚丽 2018级硕士生2018级硕士生2019级硕士生陆弯宗明瑞赵庄颜 2019级硕士生2019级硕士生2020级硕士生薛甜俞德吕方理 2020级硕士生2020级硕士生2020级硕士生已毕业实验室成员刘炎雷喜梅王逸雯 2014级博士生2015级博士生2013级硕士生郭存财李环王经纬 2013级硕士生2014级硕士生2014级硕士生罗文婷许姝雅于佳琦 2016级硕士生2017级硕士生2017级硕士生

研究领域

1.猪肠道冠状病毒（PEDV,PDCoV,SeACoV/SADS-CoV） 2.戊型肝炎病毒（HEV） 3.其它猪重要致病性病毒及新突发病毒 4.人用与兽用新型疫苗

近期论文

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1.Yang YL,Qin P,Wang B,Liu Y,Xu GH,Peng L,Zhou J,Zhu SJ*,Huang YW*.Broad cross-species infection of cultured cells by bat HKU2-related swine acute diarrhea syndrome coronavirus and identification of its replication in murine dendritic cells in vivo highlight its potential for diverse interspecies transmission.Journal of Virology,2019,93:e01448-19. 中文介绍：http://www.sohu.com/a/348071280_749000 2.Wang B,Liu Y,Ji CM,Yang YL,Liang QZ,Zhao P,Xu LD,Lei XM,Luo WT,Qin P,Zhou J,Huang YW*.Porcine deltacoronavirus engages the transmissible gastroenteritis virus functional receptor porcine aminopeptidase N for infectious cellular entry.Journal of Virology,2018,92:e00318-18. 中文介绍：http://www.virosin.org/Post/Details/PT180410000004iPlRo 3.Pan Y,Tian X,Qin P,Wang B,Zhao P,Yang YL,Wang L,Wang D,Song Y,Zhang X*,Huang YW*.Discovery of a novel swine enteric alphacoronavirus(SeACoV)in southern China.Veterinary Microbiology,2017,211:15-21. 中文介绍：http://www.sohu.com/a/197584550_749000 ESI高被引论文 4.Huang YW*,Dickerman AW,Pineyro P,Li L,Fang L,Kiehne R,Opriessnig T,Meng XJ*.Origin,Evolution,and Genotyping of Emergent Porcine Epidemic Diarrhea Virus Strains in the United States.mBio,2013,4(5):e00737-13.(*Corresponding author) Nature Research Highlights:Chinese origin for US pig virus.Nature 504,11(December 05,2013)doi:10.1038/504011f http://www.nature.com/nature/journal/v504/n7478/full/504011f.html Reuters(路透社):Scientists trace deadly piglet virus hitting U.S.farms to China.http://mobile.reuters.com/article/article/idUSBRE99L1HF20131022 ESI高被引论文 5.Huang YW,Harrall KK,Dryman BA,Opriessnig T,Vaughn EM,Roof MB,Meng XJ.Serological profile of Torque teno sus virus species 1(TTSuV1)in pigs and antigenic relationships between two TTSuV1 genotypes(1a and 1b),between two species(TTSuV1 and 2),and between porcine and human anelloviruses.Journal of Virology,2012,86(19):10628-10639. 6.Huang YW,Patterson AR,Opriessnig T,Dryman BA,Gallei A,Harrall KK,Vaughn EM,Roof MB,Meng XJ.Rescue of a porcine anellovirus(Torque teno sus virus 2)from cloned genomic DNA in pigs.Journal of Virology,2012,86(11):6042-6054. 7.Huang YW,Opriessnig T,Halbur PG,Meng XJ.Initiation at the third in-frame AUG codon of open reading frame 3 of the hepatitis E virus is essential for viral infectivity in vivo.Journal of Virology,2007,81(6):3018-3026. 8.Huang YW,Haqshenas G,Kasorndorkbua C,Halbur PG,Emerson SU,Meng XJ.Capped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs.Journal of Virology,2005,79(3):1552-1558. （所有发表的SCI文章详见“研究与成果”栏目） Ji CM,Yang XF,Qin P,Wang B*,Huang YW*.High-throughput sequencing of the porcine antibody repertoire with or without PEDV infection:A proof-of-concept study.Journal of Virological Methods,2021,in press,doi:10.1016/j.jviromet.2021.114125. Qin P,Yang YL,Hu ZM,Zhang YQ,Mei XQ,Liang QZ,Lu Z,Wang B,Chen R*,Huang YW*.A novel spike subunit 1-based ELISA reveals widespread porcine torovirus infection in eastern China.Transboundary and Emerging Diseases,2021,in press,https://doi.org/10.1111/tbed.14026. Qin P,Luo WT,Su Q,Zhao P,Zhang Y,Wang B,Yang YL,Huang YW*.The porcine deltacoronavirus accessory protein NS6 is expressed in vivo and incorporated into virions.Virology,2021,556:1-8. Zhao Z,Qin P,Huang YW*.Lysosomal ion channels involved in cellular entry and uncoating of enveloped viruses:Implications for therapeutic strategies against SARS-CoV-2.Cell Calcium,2021,94:102360. Xu LD,Zhang F,Peng L,Luo WT,Chen C,Xu P*,Huang YW*.Stable expression of a hepatitis E virus(HEV)RNA replicon in two mammalian cell lines to assess mechanism of innate immunity and antiviral response.Frontiers in Microbiology,2020,11:603699. Hao X,Wang Y,Zhu M,Zhou D,Liu R,Wang B,Huang YW*,Zhao Z*.Development of improved mumps vaccine candidates by mutating viral mRNA cap methyltransferase sites in the large polymerase protein.Virologica Sinica,2020,doi.org/10.1007/s12250-020-00326-y. Yang YL,Yu JQ,Huang YW*.Swine enteric alphacoronavirus(swine acute diarrhea syndrome coronavirus):An update three years after its discovery(invited review).Virus Research,2020,285:198024. Yang YL,Meng,F,Qin P,Herrler G,Huang YW*,Tang Y*.Trypsin promotes porcine deltacoronavirus mediating cell-to-cell fusion in a cell type-dependent manner.Emerging Microbes&Infections,2020,9:457-468. Yang YL,Qin P,Wang B,Liu Y,Xu GH,Peng L,Zhou J,Zhu SJ*,Huang YW*.Broad cross-species infection of cultured cells by bat HKU2-related swine acute diarrhea syndrome coronavirus and identification of its replication in murine dendritic cells in vivo highlight its potential for diverse interspecies transmission.Journal of Virology,2019,93:e01448-19. Lei XM,Yang YL,He YQ,Peng L,Zhao P,Xu SY,Cao H,Fang P,Qin W,Qin P,Wang B,Huang YW*.Specific recombinant proteins of porcine epidemic diarrhea virus are immunogenic,revealing their potential use as diagnostic markers.Veterinary Microbiology,2019,236:108387. Yang YL,Liang QZ,Xu SY,Mazing E,Xu GH,Peng L,Qin P,Wang B,Huang YW*.Characterization of a novel bat-HKU2-like swine enteric alphacoronavirus(SeACoV)infection in cultured cells and development of a SeACoV infectious clone.Virology,2019,536:110-118. Qin P,Du EZ,Luo WT,Yang YL,Zhang YQ,Wang B,Huang YW*.Characteristics of the Life Cycle of Porcine Deltacoronavirus(PDCoV)In Vitro:Replication Kinetics,Cellular Ultrastructure and Virion Morphology,and Evidence of Inducing Autophagy.Viruses,2019,11,455;doi:10.3390/v11050455. Hu ZM,Yang YL,Xu LD,Wang B,Qin P,Huang YW*.Porcine torovirus(PToV)—a brief review of etiology,diagnostic assays and current epidemiology.Frontiers in Veterinary Science,2019,6:120. Wang B,Liu Y,Ji CM,Yang YL,Liang QZ,Zhao P,Xu LD,Lei XM,Luo WT,Qin P,Zhou J,Huang YW*.Porcine deltacoronavirus engages the transmissible gastroenteritis virus functional receptor porcine aminopeptidase N for infectious cellular entry.Journal of Virology,2018,92:e00318-18. Ji CM,Wang B,Zhou J,Huang YW*.Aminopeptidase-N-independent entry of porcine epidemic diarrhea virus into Vero or porcine small intestine epithelial cells.Virology,2018,517:16-23. Wang Y,Liu Y,Lu M,Yang Y,Zhou D,Hao X,Zhou D,Wang B,Li J*,Huang YW*,Zhao Z*.Enhancement of safety and immunogenicity of the Chinese Hu191 measles virus vaccine by alteration of the S-adenosylmethionine(SAM)binding site in the large polymerase protein.Virology,2018,518:210-220. Zhao P,Wang B,Ji CM,Cong X,Wang M*,Huang YW*.Identification of a peptide derived from the heptad repeat 2 region of the porcine epidemic diarrhea virus(PEDV)spike glycoprotein that is capable of suppressing PEDV entry and inducing neutralizing antibodies.Antiviral Research,2018,150:1-8. Pan Y,Tian X,Qin P,Wang B,Zhao P,Yang YL,Wang L,Wang D,Song Y,Zhang X*,Huang YW*.Discovery of a novel swine enteric alphacoronavirus(SeACoV)in southern China.Veterinary Microbiology,2017,211:15-21. Qin P,Li H,Wang JW,Wang B,Xie RH,Xu H,Zhao LY,Li L,Pan Y,Song Y,Huang YW*.Genetic and pathogenic characterization of a novel reassortant mammalian orthoreovirus 3(MRV3)from a diarrheic piglet and seroepidemiological survey of MRV3 in diarrheic pigs from east China.Veterinary Microbiology,2017,208:126-136. Tian PF,Jin YL,Xing G,Qv LL,Huang YW*,Zhou JY*.Evidence of Recombinant Strains of Porcine Epidemic Diarrhea Virus,United States,2013.Emerging Infectious Diseases,2014,20(10):1735-1738.(*Corresponding author) Huang YW*,Dickerman AW,Pineyro P,Li L,Fang L,Kiehne R,Opriessnig T,Meng XJ*.Origin,Evolution,and Genotyping of Emergent Porcine Epidemic Diarrhea Virus Strains in the United States.mBio,2013,4(5):e00737-13.(*Corresponding author) Huang YW,Harrall KK,Dryman BA,Opriessnig T,Vaughn EM,Roof MB,Meng XJ.Serological profile of Torque teno sus virus species 1(TTSuV1)in pigs and antigenic relationships between two TTSuV1 genotypes(1a and 1b),between two species(TTSuV1 and 2),and between porcine and human anelloviruses.Journal of Virology,2012,86(19):10628-10639. Huang YW,Patterson AR,Opriessnig T,Dryman BA,Gallei A,Harrall KK,Vaughn EM,Roof MB,Meng XJ.Rescue of a porcine anellovirus(Torque teno sus virus 2)from cloned genomic DNA in pigs.Journal of Virology,2012,86(11):6042-6054. Huang YW,Harrall KK,Dryman BA,Beach NM,Kenney SP,Opriessnig T,Vaughn EM,Roof MB,Meng XJ.Expression of the putative ORF1 capsid protein of Torque teno sus virus 2(TTSuV2)and development of Western blot and ELISA serodiagnostic assays:Correlation between TTSuV2 viral load and IgG antibody level in pigs.Virus Research,2011,158(1-2):79-88. Huang YW,Ni YY,Dryman BA,Meng XJ.Multiple infection of porcine Torque teno virus in a single pig and characterization of the full-length genomic sequences of four U.S.prototype PTTV strains:implication for genotyping of PTTV.Virology,2010,396(2):289-297. Huang YW,Meng XJ.Novel strategies and approaches to develop the next generation of vaccines against porcine reproductive and respiratory syndrome virus(PRRSV)(Invited Review).Virus Research,2010,153(1-2):141-149. Huang YW,Dryman BA,Harrall KK,Vaughn EM,Roof MB,Meng XJ.Development of SYBR green-based real-time PCR and duplex nested PCR assays for quantitation and differential detection of species-or type-specific porcine Torque teno viruses.Journal of Virological Methods,2010,170(1-2):140-146. Huang YW,Dryman B,Li W,Meng XJ.Porcine DC-SIGN:Molecular cloning,gene structure,tissue distribution and binding characteristics.Developmental and Comparative Immunology,2009,33(4):464-480. Huang YW,Fang Y,Meng XJ.Identification and characterization of a porcine monocytic cell line supporting porcine reproductive and respiratory syndrome virus(PRRSV)replication and progeny virion production by using an improved DNA-launched PRRSV reverse genetics system.Virus Research,2009,145(1):1-8. Huang YW,Meng XJ.Identification of a porcine DC-SIGN-related C-type lectin,porcine CLEC4G(LSECtin)and its order of intron removal during splicing:Comparative genomic analyses of the cluster of genes CD23/CLEC4G/DC-SIGN among mammalian species.Developmental and Comparative Immunology,2009,33(6):747-760. Huang YW,Opriessnig T,Halbur PG,Meng XJ.Initiation at the third in-frame AUG codon of open reading frame 3 of the hepatitis E virus is essential for viral infectivity in vivo.Journal of Virology,2007,81(6):3018-3026. Huang YW,Haqshenas G,Kasorndorkbua C,Halbur PG,Emerson SU,Meng XJ.Capped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs.Journal of Virology,2005,79(3):1552-1558. Huang YW,Li L,Li JR,Yu L.Rapid construction of infectious clones of infectious bursal disease virus.Acta Biochimica et Biophysica Sinica,2003,35(4):338-344. Huang YW,Yu L,Ding HM,Li JR,Song KH.Amplification and cloning by long RT-PCR of full-length genome of larger segment of chicken infectious bursal disease viruse.Acta Biochimica et Biophysica Sinica,2001,33(3):355-359. Opriessnig T,Huang YW.Third update on possible animal sources for human COVID-19.Xenotransplantation.2021,28:e12671. Opriessnig T,Huang YW.Further information on possible animal sources for human COVID-19.Xenotransplantation.2020,27:e12651. He WT,Ji X,He W,Dellicour S,Wang S,Li G,Zhang L,Gilbert M,Zhu H,Xing G,Veit M,Huang Z,Han GZ,Huang Y,Suchard MA,Baele G,Lemey P,Su S.Genomic Epidemiology,Evolution,and Transmission Dynamics of Porcine Deltacoronavirus.Molecular Biology and Evolution,2020,37(9):2641-2654. Opriessnig T,Huang YW.Update on possible animal sources for COVID-19 in humans.Xenotransplantation.2020,27:e12621. Opriessnig T,Huang YW.Coronavirus disease 2019(COVID-19)outbreak:Could pigs be vectors for human infections?Xenotransplantation.2020,27:e12591. Wu Y,Ho W,Huang Y,Jin DY,Li S,Liu SL,Liu X,Qiu J,Sang Y,Wang Q,Yuen KY,Zheng ZM.SARS-CoV-2 is an appropriate name for the new coronavirus.Lancet.2020,395(10228):949-950. Yugo DM,Cossaboom CM,Heffron CL,Huang YW,Kenney SP,Woolums AR,Hurley DJ,Opriessnig T,Li L,Delwart E,Kanevsky I,Meng XJ.Evidence for an Unknown Agent Antigenically Related to the Hepatitis E Virus in Dairy Cows in the United States.Journal of Medical Virology,2019,91:677–686. Cao D,Ni YY,Walker M,Huang YW,Meng XJ.Roles of the genomic sequence surrounding the stem-loop structure in the junction region including the 3'terminus of ORF1 in hepatitis E virus replication.Journal of Medical Virology,2018,90(9):1524-1531. Liu S,Chen S,Li X,Wu S,Zhang Q,Jin Q,Hu L,Zhou R,Yu Z,Meng F,Wang S,Huang Y,Ye S,Shen L,Xia Z,Zou J,Feng XH,Xu P.Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses.Cell Host&Microbe,2017,21(6):754-768.e5. Rogers AJ,Huang YW,Heffron CL,Opriessnig T,Patterson AR,Meng XJ.Prevalence of the Novel Torque Teno Sus Virus Species k2b from Pigs in the United States and Lack of Association with Post-Weaning Multisystemic Wasting Syndrome or Mulberry Heart Disease.Transbound Emerg Dis.2017,64(6):1877-1883. Subramaniam S,Cao D,Tian D,Cao QM,Overend C,Yugo DM,Matzinger SR,Rogers AJ,Heffron CL,Catanzaro N,Kenney SP,Opriessnig T,Huang YW,Labarque G,Wu SQ,Meng XJ.Efficient priming of CD4 T cells by Langerin-expressing dendritic cells targeted with porcine epidemic diarrhea virus spike protein domains in pigs.Virus Res.2017,227:212-219. Thachil A,Gerber PF,Xiao CT,Huang YW,Opriessnig T.Development and application of an ELISA for the detection of porcine deltacoronavirus IgG antibodies.PLoS One,2015,10(4):e0124363.. Subramaniam S,Piñeyro P,Tian D,Overend C,Yugo DM,Matzinger SR,Rogers AJ,Haac ME,Cao Q,Heffron CL,Catanzaro N,Kenney SP,Huang YW,Opriessnig T,Meng XJ.In vivo targeting of porcine reproductive and respiratory syndromevirus antigen through porcine DC-SIGN to dendritic cells elicitsantigen-specific CD4T cell immunity in pigs.Vaccine,2014,32(50):6768-6775. Gerber PF,Gong Q,Huang YW,Wang C,Holtkamp D,Opriessnig T.Detection of antibodies against porcine epidemic diarrhea virus in serum and colostrum by indirect ELISA.The Veterinary Journal,2014,202(1):33-36. Giménez-Lirola LG,Gerber PF,Rowland RR,Halbur PG,Huang YW,Meng XJ,Opriessnig T.Development and validation of a 4-plex antibody assay for simultaneous detection of IgG antibodies against Torque teno sus virus 1(TTSuV1),TTSuV2,and porcine reproductive and respiratory syndrome virus types 1 and 2.Research in Veterinary Science,2014,96(3):543-550. Zhu Y,Yu X,Zhang Y,Ni Y,Si F,Yu R,Dong S,Huang Y,Li Z.Infectivity of a genotype 4 hepatitis E virus cDNA clone by intrahepatic inoculation of laboratory rats.Veterinary Microbiology,2013,166(3-4):405-411. Zhou L,Ni YY,Piñeyro P,Cossaboom CM,Subramaniam S,Sanford BJ,Dryman BA,Huang YW,Meng XJ.Broadening the heterologous cross-neutralizing antibody inducing ability of porcine reproductive and respiratory syndrome virus by breeding the GP4 or M genes.PLoS One,2013,8(6):e66645. Ni YY,Opriessnig T,Zhou L,Cao D,Huang YW,Halbur PG,Meng XJ.Attenuation of porcine reproductive and respiratory syndrome virus by molecular breeding of the virus envelope genes from genetically divergent strains.Journal of Virology,2013,87(1):304-313. Zhou L,Ni YY,Piñeyro P,Sanford BJ,Cossaboom CM,Dryman BA,Huang YW,Cao DJ,Meng XJ.DNA shuffling of the GP3 genes of porcine reproductive and respiratory syndrome virus(PRRSV)produces a chimeric virus with an improved cross-neutralizing ability against a heterologous PRRSV strain.Virology,2012,434(1):96-109. Cordoba L,Feagins AR,Opriessnig T,Cossaboom CM,Dryman BA,Huang YW,Meng XJ.Rescue of a genotype 4 human hepatitis E virus(HEV)from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs.Journal of General Virology,2012,93(10):2183-2194. Kenney SP,Pudupakam RS,Huang YW,Pierson FW,Leroith T,Meng XJ.The PSAP motif within the ORF3 protein of an avian strain of the hepatitis E virus is not critical for viral infectivity in vivo but plays a role in virus release.Journal of Virology,2012,86(10):5637-5646. Xiao CT,Giménez-Lirola L,Huang YW,Meng XJ,Halbur PG,Opriessnig T.The prevalence of Torque teno sus virus(TTSuV)is common and increases with the age of growing pigs in the United States.Journal of Virological Methods,2012,183(1):40-44. Cordoba L,Huang YW,Opriessnig T,Harral KK,Beach NM,Finkielstein C,Emerson SU,Meng XJ.Three amino acid mutations(F51L,T59A and S390L)on the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.Journal of Virology,2011,85(11):5338-5349. Pudupakam RS,Kenney SP,Córdoba L,Huang YW,Dryman BA,Leroith T,Pierson FW,Meng XJ.Mutational Analysis of the Hypervariable Region of the Hepatitis E Virus Reveals Its Involvement in the Efficiency of Viral RNA Replication.Journal of Virology,2011,85(19):10031-10040. Ni YY,Huang YW,Cao D,Opriessnig T,Meng XJ.Establishment of a DNA-launched infectious clone for a highly pneumovirulent strain of type 2 porcine reproductive and respiratory syndrome virus:Identification and in vitro and in vivo characterization of a large spontaneous deletion in the nsp2 region.Virus Research,2011,160(1-2):264-273. Opriessnig T,Shen HG,Pal N,Ramamoorthy S,Huang YW,Lager KM,Beach NM,Halbur PG,Meng XJ.A live-attenuated chimeric porcine circovirus type 2(PCV2)vaccine is transmitted to contact pigs but is not upregulated by concurrent infection with porcine parvovirus(PPV)and porcine reproductive and respiratory syndrome virus(PRRSV)and is efficacious in a PCV2b-PRRSV-PPV challenge model.Clinical and Vaccine Immunology,2011,18(8):1261-1268. Opriessnig T,Gomes-Neto JC,Hemann M,Shen HG,Beach NM,Huang YW,Halbur PG,Meng XJ.An experimental live chimeric porcine circovirus 1-2a vaccine decreases porcine circovirus 2b viremia when administered intramuscularly or orally in a porcine circovirus 2b and porcine reproductive and respiratory syndrome virus dual-challenge model.Microbiology and Immunology,2011,55(12):863-873. Sinha A,Shen HG,Schalk S,Beach NM,Huang YW,Meng XJ,Halbur PG,Opriessnig T.Porcine reproductive and respiratory syndrome virus(PRRSV)influences infection dynamics of porcine circovirus type 2(PCV2)subtypes PCV2a and PCV2b by prolonging PCV2 viremia and shedding.Veterinary Microbiology,2011,152(3-4):235-246. Sanford BJ,Dryman BA,Huang YW,Feagins AR,Leroith T,Meng XJ.Prior infection of pigs with a genotype 3 swine hepatitis E virus(HEV)protects against subsequent challenges with homologous and heterologous genotypes 3 and 4 human HEV.Virus Research,2011,159(1):17-22. Cao D,Huang YW,Meng XJ.The nucleotides on the stem-loop RNA structure in the junction region of the hepatitis E virus(HEV)genome are critical for virus replication.Journal of Virology,2010,84(24):13040-13044. Kwon HM,LeRoith T,Pudupakam RS,Pierson FW,Huang YW,Dryman BA,Meng XJ.Construction of an infectious cDNA clone of avian hepatitis E virus(avian HEV)recovered from a clinically healthy chicken in the United States and characterization of its pathogenicity in specific-pathogen-free chickens.Veterinary Microbiology,2011,147(3-4):310-319. Feagins AR,Cordoba L,Sanford BJ,Dryman BA,Huang YW,LeRoith T,Emerson SU,Meng XJ.Intergenotypic chimeric hepatitis E viruses(HEV)with the genotype 4 human HEV capsid protein and genotype 3 swine HEV backbone are infectious in pigs.Virus Research,2011,156(1-2):141-146. Sinha A,Shen HG,Schalk S,Beach NM,Huang YW,Halbur PG,Meng XJ,Opriessnig T.Porcine reproductive and respiratory syndrome virus(PRRSV)infection at the time of porcine circovirus type 2(PCV2)vaccination has no impact on vaccine efficacy.Clinical and Vaccine Immunology.2010,17(12):1940-1945. Shen HG,Beach N,Huang YW,Halbur PG,Meng XJ,Opriessnig T.Comparison of commercial and experimental porcine circovirus type 2(PCV2)vaccines using a triple challenge with PCV2,porcine reproductive and respiratory syndrome virus(PRRSV),and porcine parvovirus(PPV).Vaccine,2010,28(37):5960-5966. Ramamoorthy S,Huang FF,Huang YW,Meng XJ.Interferon-mediated enhancement of in vitro replication of porcine circovirus type 2 is influenced by an interferon stimulated response element in the PCV2 genome.Virus Research,2009,145(2):236-243. RS Pudupakam,YW Huang,T Opriessnig,PG Halbur,FW Pierson,XJ Meng.Deletions of the hypervariable region(HVR)in the open reading frame 1 of hepatitis E virus(HEV)do not abolish virus infectivity:Evidence for attenuation of the HVR-deletion mutants in vivo.Journal of Virology,2009,83(1):384-395. AR Feagins,T Opriessnig,YW Huang,PG Halbur,XJ Meng.Cross-species infection of specific-pathogen-free pigs 1 by a genotype 4 strain of human hepatitis E virus.Journal of Medical Virology,2008,80(8):1379–1386. N Pal,YW Huang,DM Madson,C Kuster,XJ Meng,PG Halbur,T Opriessnig.Development and validation of a duplex real-time PCR assay for the simultaneous detection and quantification of porcine circovirus type 2 and an internal control on porcine semen samples.Journal of Virological Methods,2008,149(2):217-225. Matanin BM,Huang Y,Meng XJ,Zhang C.Purification of the major envelop protein GP5 of porcine reproductive and respiratory syndrome virus(PRRSV)from native virions.Journal of Virological Methods,2008,147(1):127-135. Li L,Fang W,Li J,Huang Y,Yu L.Oral DNA vaccination with the polyprotein gene of infectious bursal disease virus(IBDV)delivered by the attenuated Salmonella elicits protective immune responses in chickens.Vaccine.2006,24(33-34):5919-5927. Li L,Wei Y,Huang Y,Yu L.Generation of VP5 deficient mutant of infectious bursal disease virus strain HZ2.Chinese Science Bulletin.2006,51(15):1909-1912. Li L,Huang YW,Wang LS,Wan WJ,Yu L.Synthesis of reassortant infectious bursal disease virus in chickens injected directly with infectious clones from different virus strains.Acta Biochimica et Biophysica Sinica,2005,37(3):192-198. Li J,Liang X,Huang Y,Meng S,Xie R,Deng R,Yu L.Enhancement of the immunogenicity of DNA vaccine against infectious bursal disease virus by co-delivery with plasmid encoding chicken interleukin 2.Virology,2004,329(1):89-100. Li J,Huang Y,Liang X,Lu M,Li L,Yu L,Deng R.Plasmid DNA encoding antigens of infectious bursal disease viruses induce protective immune responses in chickens:factors influencing efficacy.Virus Research,2003,98(1):63-74. Yu L,Li JR,Huang YW,Dikki J,Deng R.Molecular characteristics of full-length of genomic segment A of three infectious bursal disease viruses in China:two attenuated strains and a field virulent strain.Avian Diseases,2001,45(4):862-874. Li JR,Huang YW,Meng SS,Liang XY,Xie RH,Yu L.Cloning and phylogenetic analysis of interleukin-2 gene in Xiaoshan chicken,a Chinese local chicken breed.Acta Biochimica et Biophysica Sinica,2001,33(6):713-718. Song KH,Jin YF,Huang YW,Zhang YZ,Yu L.Infectious bursal disease virus structural protein VP2 expressed by a baculovirus recombinant in Bombyx mori.Acta Biochimica et Biophysica Sinica,2000,32(3):281-284. 中文论文（2016年后）：王逸雯，黄耀伟*.新发现的冠状病毒属—丁型冠状病毒.生命的化学,2016,36(4):514-518. 郭存财，刘炎，黄耀伟*.猪流行性腹泻病毒与宿主抗病毒天然免疫抑制.中国生物化学与分子生物学报，2016,32(9):967-975. 王经纬，雷喜梅，覃盼，赵鹏伟，王斌，王逸雯，李懿婷，金颢蕊，李龙，黄耀伟*.猪丁型冠状病毒荧光定量RT-PCR与S1蛋白间接ELISA检测方法的建立及应用.生物工程学报，2017,33(8):1265-1275. 覃盼，王经纬，王斌，雷喜梅，李龙，黄耀伟*.中国东部5省猪呼肠孤病毒流行病学调查与分析.浙江大学学报（农业与生命科学版）,2017,43(5):631-638. 雷喜梅，杨永乐，许姝雅，赵鹏伟，王斌，黄耀伟*.猪流行性腹泻病毒血清学及临床诊断方法研究进展.浙江大学学报（农业与生命科学版）,2018,44(2):149-156. 刘炎，黄耀伟*.猪肠道冠状病毒与入侵受体氨基肽酶N的相互作用.中国生物化学与分子生物学报，2019,35(9):952-959. 吉春苗，黄耀伟*.RNA甲基化修饰m6A调控病毒感染的研究进展.浙江大学学报（农业与生命科学版）,2021.

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