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浙江大学动物营养博士,博导,研究员,”生物饲料安全与污染防控”国家工程实验室副主任,入选国家肉鸡产业技术体系岗位科学家、教育部新世纪优秀人才、浙江省151和杭州市131人才、钱江特聘专家,主要从事家禽健康营养、环境营养调控技术研究及饲料添加剂产品开发工作,主持了国家现代农业产业技术体系岗位科学家项目、国家和浙江省自然科学基金、国家重点研发计划(子课题)、教育部新世纪优秀人才支持计划、浙江省重大科技专项和重点农业项目等课题60多项,成功开发了健康环保型饲料及高效生物饲料添加剂等系列产品,实施了产业化应用,取得了显著的社会、经济和生态效益,获国家科技进步二等奖1项、浙江省科技进步二等奖5项和三等奖3项,制修定国家和行业标准5项,授权国家发明专利2项,发表论文100余篇,其中SCI收录40多篇,参编著作8部。 教学工作 本科生:家禽生产学 研究生:饲料添加剂 工作研究项目 1、主持完成和现有课题 2019-2021环保节约型肉鸡配合饲料研发与应用,山东省枣庄英才专项 2018-2024浙江省(海盐县畜牧产业)团队科技特派员专项 2018-2020肉鸡环保饲料技术的研发与应用,浙江省重大科技专项重点农业项目(子课题) 2016-2020畜禽群体与环境互作机制研究,国家科技部重点研发计划(子课题) 2016-2020国家肉鸡产业技术体系岗位科学家项目,农业部科技专项 2016-2019母源甲硒氨酸降低种蛋孵化后期死胚率的机理研究,国家自然科学基金 2013-2017浙江省(海盐县畜牧产业)团队科技特派员专项 2012-2015肉禽种苗健康营养的关键技术研究与示范,浙江省重大科技专项重点农业项目 2011-2015国家肉鸡产业技术体系岗位科学家项目,农业部科技专项 2008-2010国家肉鸡产业技术体系岗位科学家项目,农业部科技专项 2008-2010生猪饲料饲养节流减排技术集成与示范,浙江省重大科技专项 2008-2010硒代蛋氨酸的构型营养差异化及其生物学机制,教育部新世纪优秀人才支持计划专项 2006-2010安全高效型饲料添加剂-硒代蛋氨酸的研制与应用,杭州市重大科技创新项目 2006-2008饲用缓释型赖氨酸的研制与应用,浙江省重点科技项目 2005-2008新型安全高效抗应激剂的研制与应用,重大科技横向项目 2004-2009新生体营养干预对畜禽胴体品质的影响及代谢程序化效应分析,国家973计划(子课题) 2000-2002甜菜碱对肉鸡肝脏BHMT基因表达的影响,国家自然科学基金 2000-2002畜禽肉质改良剂的研制及产业化技术研究,国家科技部地方重大专项 2000-2002改善畜禽肉质的营养调控技术研究与开发,浙江省重大科技专项 2000-2002肉质改良型专用配合饲料中试,浙江省中小型科技企业创新基金 此外,企业委托的横向项目30多项 2、主参完成和现有课题 国家自然科学基金和浙江省自然科学基金等项目10多项 教学与课程 1.猪禽生产学(本科生专业课) 2.饲料添加剂学(研究生选修课) 科研 1、家禽健康营养:研究微量元素、氨基酸、脂肪酸代谢途径及其信号转导通路的关键环节和重要靶点,开发高效营养调控生物制剂,增强家禽抗氧化、抗应激和抗病力等健康水平,提高家禽的生产性能及其产品质量。 2、家禽环境营养:研究家禽消化系统发育及肠道屏障功能的生物学机制,调控养分的消化吸收及其代谢利用,促使饲料的高效利用而减少养分排放,开发环保型家禽饲料,保障环境安全。 出版著作 2020年《体系理论与实践(肉鸡分册)》 2017年《中国动物营养研究进展》 2017年《肉鸡养殖轻简化技术图册》 2016年《中国现代农业产业可持续发展战略研究(肉鸡分册)》 2001年《中国养猪大成》 1999年《动物营养与肉的科学》 1999年《动物营养与维生素》 专利成果 占秀安,张玲,袁栋.提高种禽繁殖性能的混合型添加剂及其制备与应用,国家发明专利,ZL 201510154213 李卫芬,汪志平,余东游,占秀安,胡建强,胡彩虹.一种冬虫夏草菌粉的制备方法国家发明专利,ZL 200610050272.8 奖励荣誉 2019年枣庄英才 2014年钱江特聘专家 2008年国家现代农业(肉鸡)产业技术体系岗位科学家 2007年教育部新世纪优秀人才 2006年浙江省151人才第二层次 2005年浙江省151人才第三层次 2001年杭州市131人才第一层次 2018年浙江省科技进步三等奖 2013年浙江省科技进步二等奖 2013年浙江省民营企业科技贡献者创新奖 2007年浙江省科技进步三等奖 2004年浙江省科技进步二等奖 2003年浙江省教委科技进步一等奖 2001年国家科技进步二等奖 2001年浙江省科技进步二等奖 2000年浙江省农业科技进步一等奖 2000年浙江省科技进步二等奖 1998年浙江省科技进步二等奖

研究领域

家禽健康营养 家禽环境营养

近期论文

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(1)Wang,J.S.,Guo,T.Y.,Wang,Y.X.,Li,K.X.,Wang,Q.,Zhan,X.A.Effects of first feed intake time on growth performance,nutrient apparent metabolic rate and intestinal digestive enzyme activities in broilers.Asian-Australasian journal of animal sciences,2018,31(6),899. (2)Cao,G.T.,Zhan,X.A.,Zhang,L.L.,Zeng,X.F.,Chen,A.G.,Yang,C.M.Modulation of broilers'caecal microflora and metabolites in response to a potential probiotic bacillus amyloliquefaciens.Journal of Animal Physiology&Animal Nutrition,102(E-Suppl.1).2018. (3)Zhang,L.,Wang,J.S.,Wang,Q.,Li,K.X.,Guo,T.Y.,Xiao,X.,Wang,Y.X.,Zhan,X.A.Effects of maternal zinc glycine on mortality,zinc concentration,and antioxidant status in a developing embryo and 1-day-old chick.Biological trace element research,2018,181(2),323-330. (4)Zhang,L.,Wang,Y.X.,Xiao,X.,Wang,J.S.,Wang,Q.,Li,K.X.,Guo,T.Y.,Zhan,X.A.Effects of zinc glycinate on productive and reproductive performance,zinc concentration and antioxidant status in broiler breeders.Biological Trace Element Research,2017,178(2),1-7. (5)Xiao,X.,Wang,Y.,Liu,W.,Ju,T.,Zhan,X.Effects of different methionine sources on production and reproduction performance,egg quality and serum biochemical indices of broiler breeders.Asian-Australasian journal of animal sciences,2017,30(6),828. (6)Zhang,L.,Zhang,L.,Zhan,X.,Zeng,X.,Zhou,L.,Cao,G.,et al.Effects of dietary supplementation of probiotic,clostridium butyricum,on growth performance,immune response,intestinal barrier function,and digestive enzyme activity in broiler chickens challenged with escherichia coli k88.Journal of Animal Science and Biotechnology,2016,7(1),107-115. (7)Wang,Y.,Wang,H.,Zhan,X.Effects of different DL‐selenomethionine and sodium selenite levels on growth performance,immune functions and serum thyroid hormones concentrations in broilers.Journal of animal physiology and animal nutrition,2016,100(3),431-439. (8)Xiao,X.,Yuan,D.,Wang,Y.X.,Zhan,X.A.The protective effects of different sources of maternal selenium on oxidative stressed chick embryo liver.Biological trace element research,2016,172(1),201-208. (9)Zhang,L.,Wang,Y.X.,Zhou,Y.,Zheng,L.,Zhan,X.A.,Pu,Q.H.Different sources of maternal selenium affect selenium retention,antioxidant status,and meat quality of 56-day-old offspring of broiler breeders.Poultry Science,2014,93(9),2210. (10)Dong,Y.,Guo,X.Y.,Shi,M.L.,Lan,Z.,Wang,Y.X.,Zhan,X.Maternal dietary supplementation with two sources of selenium affects the mortality and the antioxidative status of chick embryo at different developmental periods.International Journal of Agriculture&Biology,2014,16(3),629-633. (11)Zhan,X.,Wang,H.,Yuan,D.,Wang,Y.,Zhu,F.Comparison of different forms of dietary selenium supplementation on gene expression of cytoplasmic thioredoxin reductase,selenoprotein P,and selenoprotein W in broilers.Czech Journal of Animal Science,2014,59(12),571-8. (12)Yuan,D.,Guo,X.,Shi,M.,Zheng,L.,Wang,Y.,Zhan,X.Maternal dietary supplementation with two sources of selenium affects the mortality and the antioxidative status of chick embryo at different developmental periods.International Journal of Agriculture and Biology,2014.16(3). (13)Zheng,L.,Ma,Y.E.,Gu,L.Y.,Yuan,D.,Shi,M.L.,Guo,X.Y.,Zhan,X.A.2013.Growth performance,antioxidant status,and nonspecific immunity in broilers under different lighting regimens.Journal of Applied Poultry Research,2013,22(4),798-807. (14)Yuan,D.,Zheng,L.,Guo,X.Y.,Wang,Y.X.,Zhan,X.A.Regulation of selenoprotein p concentration and expression by different sources of selenium in broiler breeders and their offspring.Poultry Science,2013,92(9),2375-2380. (15)Song,J.,Jiao,L.F.,Xiao,K.,Luan,Z.S.,Hu,C.H.,Shi,B.,Zhan,X.A.Cello-oligosaccharide ameliorates heat stress-induced impairment of intestinal microflora,morphology and barrier integrity in broilers.Animal Feed Science&Technology,2013,185(3-4),175-181. (16)Zheng,L.,Yuan,D.,Shi,M.L.,Guo,X.Y.,Ma,Y.E.,Zhan,X.A.Effects of light intensity on growth performance and antioxidative status of broilers.The Indian Journal of Animal Sciences,2013,83(11). (17)Yuan,D.,Zhan,X.A.,Wang,Y.X.Effect of selenium sources on the expression of cellular glutathione peroxidase and cytoplasmic thioredoxin reductase in the liver and kidney of broiler breeders and their offspring.Poultry Science,2012,91(4),936-942. (18)Hu,H.,Wang,M.,Zhan,X.,Li,X.,Zhao,R.Effect of different selenium sources on productive performance,serum and milk Se concentrations,and antioxidant status of sows.Biological trace element research,2011,142(3),471-480. (19)Wang,Y.,Zhan,X.,Yuan,D.,Zhang,X.,Wu,R.Influence of dietary selenomethionine supplementation on performance and selenium status of broiler breeders and their subsequent progeny.Biological trace element research,2011,143(3),1497-1507. (20)Wang,Y.,Zhan,X.,Zhang,X.,Wu,R.,Yuan,D.Comparison of different forms of dietary selenium supplementation on growth performance,meat quality,selenium deposition,and antioxidant property in broilers.Biological Trace Element Research,2011,143(1),261-273. (21)Wu,R.,Zhan,X.,Wang,Y.,Zhang,X.,Wang,M.,Yuan,D.Effect of different selemethionine forms and levels on performance of breeder hens and se distribution of tissue and egg inclusion.Biological trace element research,2011,143(2),923-931. (22)Yuan,D.,Zhan,X.,Wang,Y.Effects of selenium sources and levels on reproductive performance and selenium retention in broiler breeder,egg,developing embryo,and 1-day-old chick.Biological trace element research,2011,144(1-3),705-714. (23)Zhan,X.,Qie,Y.,Wang,M.,Li,X.,Zhao,R.Selenomethionine:an effective selenium source for sow to improve Se distribution,antioxidant status,and growth performance of pig offspring.Biological trace element research,2011,142(3),481-491. (24)Wang,Y.X.,Zhan,X.A.,Yuan,D.,Zhang,X.W.,Wu,R.J.Effects of selenomethionine and sodium selenite supplementation on meat quality,selenium distribution and antioxidant status in broilers.Czech Journal of Animal Science,2011,56(7),305-313. (25)Zhan,X.A.,Wang,M.,Ren,H.,Zhao,R.Q.,Li,J.X.,Tan,Z.L.Effect of early feed restriction on metabolic programming and compensatory growth in broiler chickens.Poultry Science,2007,86(4),654. (26)Zhan,X.A.,Min,W.,Zhao,R.Q.,Li,W.F.,Xu,Z.R.Effects of different selenium source on selenium distribution,loin quality and antioxidant status in finishing pigs.Animal Feed Science&Technology,2007,132(3),202-211. (27)Zhan,X.A.,Wang,M.,Xu,Z.R.,Li,W.F.,Li,J.X.Evaluation of caspase-dependent apoptosis during fluoride-induced liver lesion in pigs.Archives of Toxicology,2006,80(2),74-80. (28)Zhan,X.A.,Wang,M.,Xu,Z.R.,Li,J.X.,Li,J.X.Toxic effects of fluoride on kidney function and histological structure in young pigs.Fluoride.2006,39(1),22-26. (29)Zhan,X.A.,Wang,M.,Xu,Z.R.,Li,W.F.,Li,J.X.Effects of fluoride on hepatic antioxidant system and transcription of Cu/Zn SOD gene in young pigs.Journal of Trace Elements in Medicine and Biology,2006,20(2),83-87. (30)Zhan,X.A.,Li,J.X.,Xu,Z.R.,Zhao,R.Q.Effects of methionine and betaine supplementation on growth performance,carcase composition and metabolism of lipids in male broilers.British Poultry Science,2006,47(5),576-580. (31)Zhan,X.A.,Li,J.X.,Xu,Z.R.,Wang,M.2005.Effects of fluoride on pancreatic digestive enzyme activities and ultrastructure in young pigs.Fluoride,38(3),215. (32)Xu,Z.R.,Hu,C.H.,Xia,M.S.,Zhan,X.A.,Wang,M.Q.Effects of dietary fructooligosaccharide on digestive enzyme activities,intestinal microflora and morphology of growing pigs.Poultry Science,2003,82(6),1030. (33)Xu,Z.R.,Wang,M.Q.,Mao,H.X.,Zhan,X.A.,Hu,C.H.Effects of l-carnitine on growth performance,carcass composition,and metabolism of lipids in male broilers.Poultry Science,2003,82(3),408-13. (34)王倩,郑兰,王江水,郭天宇,占秀安.光照时间和强度互作对黄羽肉鸡生长性能和免疫功能的影响[J].中国畜牧杂志,2017,53(7):107-112. (35)孙标,王倩,占秀安.光照优化管理对岭南黄鸡生产性能、抗氧化和抗应激功能的影响[J].中国家禽,2017,39(12):34-38. (36)肖雪,李凯旋,袁栋,占秀安.种母鸡饲粮不同硒源及添加水平对后代肉鸡生长性能、肉品质、硒沉积和抗氧化功能的影响[J].动物营养学报,2016,28(12):3792-3802. (37)曹广添,占秀安,张玲玲,曾新福,刘金松,杨彩梅.解淀粉芽孢杆菌对肉鸡生长性能、小肠发育和血清生化指标及免疫功能的影响[J].中国畜牧杂志,2016,52(3):31-35. (38)鞠婷婷,郭孝烨,随佳佳,肖雪,占秀安.不同剂型丁酸钠对脂多糖应激肉鸡血清生化指标、抗氧化和抗炎功能的影响[J].动物营养学报,2015,27(10):3146-3154. (39)周颖,周建群,浦琴华,顾林英,占秀安.复合寡糖微量元素络合物对育肥猪生长性能、养分消化率及微量元素排泄量的影响[J].中国饲料,2015(3):7-10. (40)鞠婷婷,郭孝烨,肖雪,随佳佳,占秀安,浦琴华,顾林英.饲粮添加丁酸钠对黄羽肉鸡生产性能、血清生化指标、消化功能和肠道形态的影响[J].中国家禽,2015,37(9):32-36. (41)王永侠,茅慧玲,占秀安.不同构型硒代蛋氨酸对肉鸡的作用效果[J].动物营养学报,2015,27(12):3861-3870. (42)李治学,占秀安,汪以真.饲用氧化锌替代思路研究进展[J].中国畜牧杂志,2015,51(20):76-80. (43)郭丽青,占秀安.早期营养对肉鸡肠道发育和免疫功能影响的研究进展[J].中国家禽,2015,37(18):37-40. (44)刘文斐,占秀安.3种饲用除臭剂对肉鸡生长性能和肠道菌群及排泄物氨逸失的影响[J].中国畜牧杂志,2015,51(17):49-53. (45)刘文斐,刘伟龙,占秀安,浦琴华.不同形式蛋氨酸对肉种鸡生产性能、免疫指标及抗氧化功能的影响[J].动物营养学报,2013,25(9):2118-2125. (46)郭孝烨,史明雷,郑兰,顾林英,张云兵,谭莉,占秀安.复合芽孢杆菌制剂对肉鸡生长性能、盲肠菌群和排泄物氨逸失的影响[J].中国畜牧杂志,2013,49(11):70-73. (47)谭莉,袁栋,张云兵,占秀安.不同类型芽孢杆菌制剂对肉鸡生长性能和排泄物氨逸失的影响[J].动物营养学报,2012,24(5):877-885. (48)夏磊,占秀安,朱巧明,王永侠,刘伟龙,马玉娥.γ-氨基丁酸对热应激肉种鸡产蛋性能和繁殖性能的影响[J].动物营养学报,2012,24(1):137-144. (49)马玉娥,占秀安,朱巧明,刘伟龙,夏磊.饲粮色氨酸水平对黄羽肉种鸡生产性能、抗氧化功能及血清生化指标的影响[J].动物营养学报,2011,23(12):2177-2182. (50)刘伟龙,占秀安,王永侠,郄彦昭,武如娟.肉种鸡补充硒代蛋氨酸对后代肉鸡肉质的影响及作用机理[J].动物营养学报,2011,23(3):417-425. (51)胡鹏,占秀安,郄彦昭,王永侠,赵茹茜.母种猪饲粮添加DL-硒代蛋氨酸对后代乳猪胰脏硒含量、抗氧化能力、消化酶活性以及GSH-Px mRNA表达的影响[J].动物营养学报,2010,22(5):1361-1366. (52)武如娟,占秀安,赵茹茜,王永侠,张习文,郄彦昭.不同构型硒代蛋氨酸对岭南黄父母代肉种鸡生产性能和组织硒沉积的影响[J].动物营养学报,2010,22(1):151-156.

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