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胡福良,男,理学博士,教授,博士生导师,国务院政府特殊津贴获得者。1964年6月出生,浙江东阳人,1985年7月毕业于浙江农业大学畜牧兽医系畜牧专业,同年留校任教。先后担任辅导员、助教、助理研究员、副研究员、研究员、教授。其间,1993年9月至1997年7月在浙江农业大学植物保护系攻读昆虫学硕士学位,获理学硕士;2002年2月至2005年4月在南非罗德斯大学(Rhodes University)动物与昆虫学系攻读博士学位,获理学博士。曾任浙江大学动物科学学院院长助理(2009-2014)、特种经济动物科学系副主任(1999-2009)。现任浙江大学蚕蜂研究所所长,动物科学学院学术(教授)委员会主任。 长期从事蜜蜂、蜂产品及功能性食品科学的科研与教学工作,在蜜蜂生物学、蜂产品的化学成分、生物学活性、质量控制及深加工技术等领域有较深入的研究,取得了多项原创性成果。先后主持国家自然科学基金、科技部、教育部、浙江省等各级各类课题60余项;获国家技术发明二等奖2项、国家科技进步三等奖1项、省部级奖6项;获得授权国家发明专利38项;制订国家及行业标准10项;主编、副主编著作10部;发表学术论文400余篇,其中,SCI收录110余篇,总被引2100余次,H指数24;培养蜂学博士24人、硕士30人。先后荣获“浙江省青少年英才”“浙江省杰青”“浙江省151人才”“浙江省优秀教师”“浙江省优秀科技工作者”“浙江省三育人先进个人”“浙江大学三育人标兵”“杭州市钱江特聘专家”等称号。 教学与课程 讲授课程 本科生通识课:《蜜蜂、生态与人类》 本科生专业课:《蜜蜂学》《蜜蜂产品学》 研究生专业课:《特种经济动物科学专题》《特种经济动物资源应用及养殖技术》 科研 主持的各级各类课题一览表 序号 项目名称 来源 起止年月 01 工蜂胎免疫活性肽的结构与功能研究 国家自然科学基金 2001.01~2001.12 02 意蜂多王群蜂王的产卵特性及蜂王间相互作用关系的研究 国家自然科学基金 2004.01~2006.12 03 意大利蜂多王群信息素合成和接收关键组织蛋白质组研究 国家自然科学基金 2008.01~2010.12 04 蜜蜂miRNA的全基因组挖掘及其在级型分化过程中的表达差异研究 国家自然科学基金 2009.01~2011.12 05 基于多指标成分定量结合指纹图谱定性的蜂胶真实性评价体系的构建及机理研究 国家自然科学基金 2013.01~2016.12 06 基于特征性脂肪酸合成机理及抗氧化活性物质基础的蜂王浆质量评价研究 国家自然科学基金 2019.01~2022.12 07 蜂产品深加工及产业化开发 科技部 2001.01~2003.12 08 酶法改性蜂胶黄酮苷技术 科技部 2006.08~2008.12 09 基于多王群和寄生海角蜂的蜜蜂群内生殖共享与冲突研究 科技部 2014.01~2016.12 10 蜂王浆新鲜度指标与评定方法研究 教育部 2008.01~2009.12 11 蜜蜂种质及蜂产品生产加工技术引进与创新 农业部 2008.01~2008.12 12 不同蜜蜂生产区抗逆增产技术体系研究与示范 农业部 2007.01~2010.12 13 现代农业(蜂)产业技术体系 农业部 2008.01~2015.12 14 现代农业(蜂)产业技术体系 农业部 2016.01~2020.12 15 工蜂胎的开发利用研究 浙江省科委 1995.01~1996.12 16 蜂产品深加工产业化技术与产品开发研究 浙江省科技厅 2001.01~2002.06 17 蜂业资源产品深加工及产业化 浙江省科技厅 2001.01~2003.12 18 蜂源性免疫增强剂(BLP)的中试 浙江省科技厅 2002.01~2003.12 19 蜂胶功效成分提取新技术研究及系列产品开发 浙江省科技厅 2003.10~2005.12 20 多王群的生物学特性及其在养蜂生产中的应用研究 浙江省科技厅 2004.01~2005.12 21 意蜂多王群饲养管理技术体系的建立与示范 浙江省科技厅 2006.06~2008.06 22 优质抗病蜜蜂新品系选育 浙江省科技厅 2012.01~2015.12 23 浙江浆蜂优质抗逆新品系选育 浙江省科技厅 2016.01~2020.12 24 浙江省杰出青年基金项目 浙江省自然科学基金 2010.01~2012.12 25 浙江中蜂蜂蜜质量研究 浙江省农业重大技术 协同推广计划 2019.04~2021.04 26 蜂胶功能因子研究及蜂胶新产品的研制开发 上海市农委 2014.04~2016.12 27 中蜂有机养殖与蜂蜜加工技术集成及产业化 广东省产学研结合项目 2010.05~2012.04 28 新型蜂胶功能食品的创制与产业化开发 浙江省教育厅 2008.01~2010.12 29 Gene profiling分析测试 中科院上海药物研究所 2010.10~2010.12 30 蜂业可持续发展支撑体系研究 中国农科院蜜蜂研究所 2010.04~2010.12 31 蜂产品溯源软件系统的应用和提高 中国农科院蜜蜂研究所 2010.11~2011.12 32 蜂产品中兽药残留代谢规律及蜂产品质量评价技术开发 中国农科院蜜蜂研究所 2010.05~2011.12 33 蜂胶样本的采集和鉴别 中国农科院蜜蜂研究所 2013.06~2014.06 34 蜂胶品质和真伪识别方法 中国农科院蜜蜂研究所 2015.07~2016.06 35 蜂胶的纳米化技术研究及系列产品的研制开发 杭州市科技局 2004.01~2006.12 36 杭州蜂业科技创新服务平台专项 杭州市科技局 2005.12~2009.12 37 蜂产品质量控制和深加工关键技术研究及示范 宁波市科技局 2012.03~2013.12 38 中国红蜂胶抗糖尿病作用的研究 国际合作 2007.08~2008.07 39 中药抗炎免疫机理研究 横向课题 2001.06~2002.05 40 蜂王浆、蜂胶深加工产品的研制开发 横向课题 2001.09~2002.12 41 蜂产品深加工技术研究 横向课题 2001.11~2002.11 42 蜂胶的深加工技术研究与产业化 横向课题 2002.03~2003.12 43 “天宝”蜂产品开发研究 横向课题 2002.07~2005.04 44 复方中草药蜂药防治效果的研究 横向课题 2003.01~2003.12 45 蜂胶类保健产品的研制开发 横向课题 2003.03~2004.06 46 “蜂之语”系列蜂产品的研究开发 横向课题 2003.05~2008.04 47 蜂胶精深加工技术研究及新产品开发 横向课题 2003.10~2004.12 48 新型蜂胶类保健食品的研制开发 横向课题 2007.06~2008.06 49 蜂蜜泡腾片的研制 横向课题 2007.09~2008.08 50 蜂产品加工厂扩建(技术咨询) 横向课题 2007.11~2008.11 51 平湖意蜂遗传标记的调查分析 横向课题 2008.04~2009.04 52 蜂胶与杨树胶真伪鉴别技术 横向课题 2010.02~2011.02 53 蜂蜜发酵深加工系列产品研发 横向课题 2010.10~2011.10 54 '福赐德'系列蜂产品的研制 横向课题 2011.03~2014.03 55 “控螨饵料”控制蜂螨的作用及安全性研究 横向课题 2011.04~2012.06 56 “蜂乃宝”系列蜂产品的研究开发 横向课题 2011.07~2016.07 57 蜂胶深加工技术研究开发 横向课题 2012.10~2013.12 58 蜂产品质量提升与新产品研制 横向课题 2013.01~2015.01 59 一种蜂王浆新鲜度的快速检测方法 横向课题 2014.06~2023.06 60 提高蜂产品生物利用率的深加工技术创新与应用 横向课题 2014.08~2015.12 61 “千岛金蜂”中华蜜蜂资源的保护与利用 横向课题 2015.06~2016.12 62 蜂产品生物医用材料的开发利用研究 横向课题 2016.01~2018.12 63 长白山蜂胶质量评价体系研究与应用 横向课题 2016.05~2018.06 64 《丽水市中蜂产业发展规划》的制定 横向课题 2017.09~2017.12 65 《龙泉市中蜂产业发展规划》的制定 横向课题 2017.11~2018.10 66 系列蜂产品的研究开发 横向课题 2020.03~2025.02 研究与成果 长期从事蜜蜂、蜂产品及功能性食品科学的研究。先后主持国家自然科学基金、科技部、教育部、浙江省等各级各类课题60余项;获国家技术发明二等奖2项、国家科技进步三等奖1项,省部级奖6项;获得授权国家发明专利38项;制订国家及行业标准8项;主编、副主编专著10部;发表学术论文400余篇,其中,SCI收录100余篇。 在蜜蜂生物学、蜂产品的化学成分、生物学活性、质量控制及深加工技术等领域有较深入的研究,取得了多项原创性成果: 一、采用生物诱导与环境诱导相结合的方法,在国内外率先成功组建无障碍同巢意蜂多王群,突破了蜜蜂单王垄断生殖权的基本生物学规律。试验结果表明,应用多王群为生产群补群可显著提高蜂产品产量,应用多王群为生产群提供日龄一致的幼虫可显著减轻蜂农劳动强度,节省劳力;通过对多王群形成机制的研究,首次发现蜂王可在不评估对手实力的情况下,仅基于对自身实力的判断选择规避可能致死的打斗。同时,基于基因表达谱的研究,证实了多王群内蜂王间存在信息素竞争,首次发现蜂王上颚腺信息素并不是蜂王生殖力的指示信号,而更有可能是工蜂卵巢发育的抑制因子,从而揭示了蜂王间达到生殖共享的机制。蜜蜂多王群既为养蜂业创立了独特的饲养管理方式,又为社会性昆虫的研究提供了新的生物模式。 二、对蜂胶的植物来源、功效成分、生物学活性、质量控制及深加工技术进行了系统的研究,出版了我国第一部蜂胶基础研究专著;创立了基于水杨苷和邻苯二酚的HPLC蜂胶与杨树胶的鉴别方法和多指标成分定量结合指纹图谱定性的中国蜂胶质量评价方法,并牵头制定了蜂胶真伪鉴别和标志性成分检测的国家标准与行业标准,解决了困扰蜂胶行业十多年的技术难题。同时,将纳米技术、微胶囊技术和酶解技术等高新技术应用于蜂胶的深加工,提高了蜂胶产品的附加值和生物利用度。 三、对蜂王浆的质量控制尤其是新鲜度指标与评定方法进行了系统研究,从微观到宏观,从定性、半定量到定量建立了多项新鲜度(品质)评价新技术,提出了相关的评价指标和阈值,为科学评价蜂王浆新鲜度(品质)提供了理论依据和技术手段;以蜂王浆优质高效生产和质量安全评价为目的,建立了蜂王浆优质高效生产体系,实现了从源头控制蜂王浆质量。 四、对蜂胶及其活性成分的抗氧化、抗炎、抗肿瘤、抗糖尿病、促创伤修复作用及其分子机制,对蜂王浆及其活性成分的抗炎、抗氧化、抗衰老作用及其分子机制进行了深入研究,为蜂胶和蜂王浆的开发利用提供了理论依据。 五、对国内外不同种类蜂蜜的理化特性和生物学活性进行了较系统研究,基于中蜂蜂蜜与意蜂蜂蜜蜂源性物质的差异,建立了4种中蜂蜂蜜与意蜂蜂蜜的鉴别方法,并基于MRJP2开发了第一款中蜂蜂蜜与意蜂蜂蜜鉴别的ELISA试剂盒。 六、率先对工蜂胎的营养价值、生物学活性及开发利用价值进行了较系统研究,开辟了一条新的蜂产品综合利用途径。 七、在蜜蜂基础生物学研究方面,(1)首次在中国境内发现了“无政府主义”蜂群,通过对这些特殊蜂群生殖特性的研究,并对其上颚腺分泌物的分析,首次阐述了工蜂上颚腺信息素作为调控因子在无政府主义生殖劳动分工的作用,并说明有王群工蜂生殖现象可能比之前认为的更加普遍;(2)在国内外率先系统研究了蜜蜂基因组中的miRNA,尤其是蜂王幼虫和工蜂幼虫的mRNA和miRNA的表达差异,为国际miRBase数据库中蜜蜂miRNA贡献了大部分的数据;(3)对蜜蜂属(Apis)系统发育及中国大蜜蜂(A.dorsata)遗传分化进行了深入研究,明确了蜜蜂属系统发育关系,确定了海南岛大蜜蜂群体和大陆大蜜蜂群体之间的遗传分化;(4)与南京大学团队合作,研究发现蜂粮中的植物源microRNA调控蜜蜂级型分化,这是首次关于植物源microRNA可以跨界调控动物体的表型和发育机制的报道;(5)首次建立了一套用于蜜蜂脑机接口及其神经机理研究的方法系统,并初步揭示了蜜蜂可能的飞行起始神经通路及其特性。 在产学研合作方面,主持建设了“杭州蜂业科技创新服务平台”,主持完成了多项与企业合作的重大项目,取得了十分显著的社会经济效益。 获得的科技成果奖励如下: 国家科技进步三等奖(排名第三),1990 浙江省科技进步一等奖(排名第二),1994 国家技术发明二等奖(排名第三),1995 浙江省科技进步三等奖(排名第五),2003 嘉兴市科技进步二等奖(排名第一),2007 国际蜜蜂研究会(IBRA)“Eva Crane奖”,2009 浙江省科学技术三等奖(排名第一),2010 中国农业科学院科学技术二等奖(排名第二),2012 北京市科学技术三等奖(排名第二),2012 浙江省农业丰收奖三等奖(排名第三),2013 中华农业科技奖科学研究成果一等奖(排名第二),2015 全国农牧渔业“丰收奖”一等奖(排名第二),2016 山东省高等学校科学技术奖一等奖(排名第二),2016 国家技术发明二等奖(排名第三),2017 出版著作 主编、副主编的著作: 胡福良,郎海芳主编.《蜜蜂标准化养殖技术手册》,杭州:浙江科学技术出版社,2020 吴杰主编,胡福良等副主编.《现代农业产业技术体系建设理论与实践----蜂业分册》,北京:中国农业科学技术出版社,2020 胡福良等著.《蜂胶研究》,杭州:浙江大学出版社,2019 吴杰主编,胡福良等副主编.《蜜蜂学》,北京:中国农业出版社,2012 曾志将主编,姜玉锁、胡福良等副主编.《养蜂学》(全国统编教材),北京:中国农业出版社,2009 陈润龙,胡福良等编.《蜜蜂标准化生产技术》,杭州:浙江科学技术出版社,2008 胡福良著.《蜂胶药理作用研究》,杭州:浙江大学出版社,2005 胡福良,李英华,朱威编著.《蜂胶蜂花粉加工技术》,北京:金盾出版社,2005 胡福良,黄坚编著.《蜂王浆优质高产技术》,北京:金盾出版社,2004 胡福良,陈黎红编著.《蜜蜂高效养殖7日通》,北京:中国农业出版社,2004 专利成果 授权的国家发明专利 专利名称(专利号) 授权时间 发明人 1 一种能抑制肿瘤细胞生长的免疫增强剂 (ZL 97111348.3) 2000.01 胡福良、陈民利、陈盛禄 2 一种水溶性蜂胶的提取方法及用途 (ZL 03150648.8) 2006.01 胡福良、王超敏、李英华 3 纳米蜂胶制品的制备方法 (ZL 200510049745.8) 2007.03 胡福良、李英华、朱威 4 亚微米蜂胶微胶囊的制备方法 (ZL 200510049746.2) 2007.04 胡福良、李英华、朱威 5 意大利蜂同巢多王群的组建方法和饲养管理方法 (ZL 200410084705.2) 2008.10 胡福良、金水华、姜全清、符林杰、潘永根、李新鑫、郑火青 6 一种食品新鲜度的快速检测试剂及使用方法 (ZL 200710067215.5) 2010.01 胡福良、吴黎明、郑火青、朱威 7 一种蜂王浆新鲜度的快速检测试剂及使用方法 (ZL 200710067214.0) 2010.07 胡福良、吴黎明、郑火青、朱威 8 一种酸解蜂胶黄酮苷的方法(ZL 200810063053.2) 2011.04 胡福良、刘亚男、李英华 9 一种柚苷酶水解蜂胶黄酮苷的方法 (ZL 200810063054.7) 2011.05 胡福良、刘亚男、李英华 10 一种室内人工饲养蜜蜂的装置 (ZL 200610155514.X) 2011.06 胡福良、郑火青、程艳华、 刘亚男 11 一种测定蜂王浆新鲜度的方法 (ZL 200810116945.4) 2011.11 吴黎明、薛晓锋、赵静、 李熠、彭文君、胡福良 12 一种具有吸湿保湿功能的蜂王浆酶解产物 (ZL 200710070447.6) 2012.01 胡福良、季文静 13 一种蜂王浆新鲜度的检测方法 (ZL 200910154567.3) 2012.06 郑火青、胡福良、魏文挺、 易松强 14 一种蜂王浆新鲜度的红外光谱评价方法 (ZL 200810117290.2) 2012.07 吴黎明、胡福良、赵静、孙素琴、周群 15 一种蜂王浆品质的评价方法(ZL 200810223379.7) 2012.07 吴黎明、胡福良、薛晓锋、赵静、李熠、周金慧 16 一种评价蜂王浆贮存条件适合性的方法 (ZL 200810223381.4) 2012.07 吴黎明、胡福良、薛晓锋、赵静、李熠、周金慧 17 一种评价蜂王浆贮存条件适合性的方法 (ZL 200810223497.8) 2012.07 吴黎明、胡福良、薛晓锋、赵静、李熠、周金慧 18 蜂胶与杨树胶的鉴别方法(ZL 201010180675.0) 2012.10 胡福良、张翠平 19 一种蜂胶微胶囊的制备方法及应用 (ZL 201110067242.9) 2013.01 胡福良、张翠平 20 一种提高蜂王浆中10-羟基-2-癸烯酸含量的方法 (ZL 201110357224.4) 2013.06 胡福良、魏文挺、郑火青 21 一种防治蜂螨的药物及用途(ZL 201110395445.0) 2013.07 郑火青、胡福良、苏晓玲 22 一种饲养蜜蜂的装置及应用(ZL 201110395444.6) 2013.09 郑火青、胡福良、苏晓玲 23 一种蜂胶与杨树胶的鉴别方法(ZL200910101428.4) 2014.04.16 胡福良、张翠平 24 一种酒神菊型蜂胶质量控制方法 (ZL 201310075055.4) 2014.11.12 张翠平、胡福良、黄帅 25 一种蜂胶与虫草菌丝粉组合物及制备和应用 (ZL 201310540701.X) 2015.04.29 张翠平、胡福良、柳刚 26 一种与实验室旋转蒸发仪配套的简易水循环装置 (ZL 201310225564.0) 2015.04.29 胡福良、平舜、张翠平、郑火青 27 一种杨树胶中特有成分的分离纯化方法及应用 (201310721079.2) 2015.07.08 胡福良、黄帅、张翠平、 王凯、甘礼设 28 一种酒神菊属型蜂胶质量控制的方法及应用 (ZL 201310543934.5) 2015.07.08 张翠平、胡福良、黄帅、刘嘉 29 一种蜂王浆微胶囊的制备方法及应用 (ZL 20140136195.2) 2016.01.06 张翠平、胡福良 30 蜂王浆中三种脂肪酸成分含量的检测方法及应用 (ZL 201410417420.X) 2017.01.11 胡福良、吴雨祺、魏文挺、 郑火青 31 一种穿心莲水提物的制药用途 (ZL 201510078065.2) 2018.01.12 郑火青、陈秀贤、胡福良、王帅 32 一种防治蜜蜂微孢子虫病的中药组合物及其用途 (ZL 2015103026500.6) 2018.04.17 郑火青、陈秀贤、胡福良、张翠平 33 一种防治蜜蜂微孢子虫病的药物及其用途 (ZL 201510302635.1) 2018.04.20 郑火青、陈秀贤、胡福良、李利 34 一种巴西绿蜂胶质量控制方法 (ZL 201610279885.2) 2018.04.28 张翠平、胡福良、申小阁、刘嘉 35 一种口腔护理液及其制备方法 (ZL 201610274188.8) 2018.04.28 张翠平、胡福良、孙德官 36 天然植物提取物及防治蜜蜂微孢子虫病的用途 (ZL 201410672287.2) 2018.05.29 郑火青、陈秀贤、胡福良、 贡红日 37 一种中国蜂胶黄酮提取物及制备方法和应用 (ZL 201710068269.7) 2019.04.30 胡福良、程晓雨、郑宇斐、 张翠平、郑火青 38 检测中蜂蜂蜜与意蜂蜂蜜的ELISA检测试剂盒 (ZL 201910550683.0) 2020.06.16 胡福良、张言政、郑火青、张翠平 荣誉奖励 浙江省优秀教师,1987 浙江省第三届青少年英才奖,1995 国务院“政府特殊津贴”专家,1999 浙江大学“圣雄”奖教金,2001 大江园丁奖,2002 对全国蜂产品行业发展做出突出贡献的先进个人,2005 中国蜂产品行业优秀科技创新人才,2007 浙江省新农村建设带头人“金牛奖”提名奖,2007 浙江省教育系统“事业家庭兼顾型”先进个人,2007 浙江省“新世纪151人才工程”第二层次,2008 浙江大学优秀共产党员,2009 浙江省杰出青年基金获得者,2010 杭州市钱江特聘专家,2011 浙江大学先进工作者,2011 浙江大学师德先进个人,2015 浙江省优秀科技工作者,2016 浙江大学大北农突出贡献奖,2017 中国蜂胶产业突出贡献奖,2018 浙江大学优秀研究生德育导师,2018 “蜂耘三十年”杰出教育工作者,2019 全国蜂业突出贡献奖,2019 浙江大学“三育人”标兵,2020 浙江省“三育人”先进个人,2020 培养毕业研究生 团队培养毕业研究生一览表 姓名 毕业时间 现工作单位 博士 吴黎明 2008 中国农业科学院蜜蜂研究所 吴杰 2009 中国农业科学院蜜蜂研究所 郑火青 2009 浙江大学动物科学学院 朱威 2010 浙江大学工业技术转化研究院 张翠平 2010 浙江大学动物科学学院 玄红专 2011 聊城大学生命科学学院 李雅晶 2011 浙江经贸职业技术学院 陈璇 2012 浙江省中医药研究院 曹联飞 2012 浙江省农业科学院畜牧所 季文静 2013 中国平安集团公司杭州分公司 牛德芳 2014 江苏农牧科技职业学院 赵慧霞 2014 中国科学院深圳先进技术研究院 魏文挺 2014 杭州答尔问教育咨询有限公司 王凯 2016 中国农业科学院蜜蜂研究所 蔺哲广 2017 扬州大学动物科技学院 吴雨祺 2018 杭州凯莱谱精准医疗检测技术有限公司 潘永明 2019 浙江中医药大学 陈伊凡 2019 浙江省农业科学院食品所 张言政 2019 浙江大学动物科学学院 王帅 2019 浙江大学动物科学学院 郑宇斐 2020 浙江大学医学院附属邵逸夫医院 蒋侠森 2020 阜阳师范大学生物与食品工程学院 硕士 李英华 2002 复旦大学附属上海第五人民医院 玄红专 2003 聊城大学生命科学学院 詹耀锋 2003 杭州市环境保护局 朱威 2004 浙江大学工业技术研究院 张挺 2006(联培) 福建省南平市食品药品监督管理局 刘亚男 2008(联培) 北京中农盛世农业科技有限公司 程艳华 2008(联培) 青海省大数据有限责任公司 褚亚芳 2010 雀巢健康科学(中国)有限公司 易松强 2010 江西省畜牧技术推广站 苏晓玲 2012 浙江省金华市农业科学院 张金连 2012 厦门大学嘉庚学院 卢媛媛 2014 浙江大学动物科学学院 平舜 2015 劢强科技(上海)有限公司 黄帅 2015 澳大利亚墨尔本大学 张江临 2015 美国南加州大学医学院 李诗怡 2016 浙江省公众信息产业有限公司 申小阁 2016 重庆交通职业学院 曹雪萍 2016 上海希元生物科技有限公司 贡红日 2016 南开大学 陈秀贤 2016 德国柏林自由大学 陈晓雨 2017 浙江省粮食干部学校 李利 2017 中国电信股份有限公司杭州分公司 张迎迎 2017 安徽省合肥市农业委员会 陈佳玮 2018 天堃医药科技(杭州)有限公司 秦瑶 2018 北京市通州区西集镇政府 许瑛瑛 2018 杭州泽厚生物科技有限公司 刘奕辰 2019 天津市宁河区廉庄镇政府 思娟娟 2019 宁夏银川市兴庆区月牙湖乡政府 史旖桢 2019 河南科技大学 田静 2020 杭州学而思教育咨询有限公司 陈曦 2020 北京京东世纪贸易有限公司 陈功文 2020 浙江大学动物科学学院

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SCI收录论文: Gongwen Chen,Yuqi Wu,Jie Deng,Zhengsheng Wen,Shuai Wang,Yanping Chen,Fuliang Hu,Huoqing Zheng*.Seasonal variation of viral infections between the eastern honey bee(Apis cerana)and the western honey bee(Apis mellifera).MicrobiologyOpen,2021,10:e1162.https://doi.org/10.1002/mbo3.1162 Zheguang Lin,Shuai Wang,Peter Neumann,Gongwen Chen,Paul Page,Li Li,Fuliang Hu,Huoqing Zheng*,Vincent Dietemann.Population genetics and host specificity of Varroa destructor mites infesting eastern and western honeybees.Journal of Pest Science,2021.https://doi.org/10.1007/s10340-020-01322-7. Mengmeng You,Zhuoning Miao,Olimpia Sienkiewicz,Xiasen Jiang,Xin Zhao*,Fuliang Hu*.10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.International Immunopharmacology,2020,84:106501.https://doi.org/10.1016/j.intimp.2020.106501 Yuqi WU,Yufei ZHENG,Hongmei LI-BYARLAY,Yizhen SHI,Shuai WANG,Huoqing ZHENG,Fuliang HU*.CYP6AS8,a cytochrome P45,is associated with the 10-HDA biosynthesis in honey bee(Apis mellifera)workers.Apidologie,2020,51:1202-1212.doi:10.1007/s13592-019-00709-5 Wei Yang*,Fu-liang Hu,Xiao-feng Xu.Bee venom and SARS-CoV-2.Toxicon,2020,181:69-70.https://doi.org/10.1016/j.toxicon.2020.04.105 Shuai Wang,Zheguang Lin,Gongwen Chen,Paul Page,Fuliang Hu,Qingsheng Niu,Xiaoling Su,Panuwan Chantawannakul,Peter Neumann,Huoqing Zheng*,Vincent Dietemann.Reproduction of ectoparasitic mites in a coevolved system:Varroa spp.–Eastern honey bees,Apis cerana.Ecology and Evolution,2020,10(24):14359-14371.doi:10.1002/ece3.7038 Fan Wu,Xin-Mi Song,Yi-Lei Qiu,Huo-Qing Zheng,Fu-Liang Hu&Hong-Liang Li*.Unique dynamic mode between Artepillin C and human serum albumin implies the characteristics of Brazilian green propolis representative bioactive component.Scientific Reports,2020,10:17277.https://doi.org/10.1038/s41598-020-74197-4 Mengmeng You,Zhuoning Miao,Jing Tian&Fuliang Hu*.Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy.European Journal of Nutrition,2020,59:2875-2892.https://doi.org/10.1007/s00394-019-02128-9 Zheng Yufei,Wu Yuqi,Hu Binyue,Tao Lingchen,Chen Xi,Dixon Hoffelt,and Hu Fuliang*.Chrysin Inhibits Melanoma Tumor Metastasis via Interfering with the FOXM1/β-Catenin Signaling.Journal of Agricultural and Food Chemistry,2020,https://dx.doi.org/10.1021/acs.jafc.0c03123 Xia-sen Jiang,Hong-qing Xie,Chun-guang Li,Meng-meng You,Yu-fei Zheng,George Q.Li,Xiang Chen,Cui-ping Zhang,and Fu-liang Hu*.Chinese Propolis Inhibits the Proliferation of Human Gastric Cancer Cells by Inducing Apoptosis and Cell Cycle Arrest.Evidence-Based Complementary and Alternative Medicine,Volume 2020,Article ID 2743058,11 pages.https://doi.org/10.1155/2020/2743058 Xiasen Jiang,Linchen Tao,Chunguang Li,Mengmeng You,George Q.Li,Cuiping Zhang and Fuliang Hu*.Grouping,Spectrum–Effect Relationship and Antioxidant Compounds of Chinese Propolis from Different Regions Using Multivariate Analyses and Off-Line Anti-DPPH Assay.Molecules,2020,25,3243.doi:10.3390/molecules25143243 Yuqi Wu,Yufei Zheng,Yanan Chen,Shuai Wang,Yanping Chen,Fuliang Hu*and Huoqing Zheng*.Honey bee(Apis mellifera)gut microbiota promotes host endogenous detoxification capability via regulation of P450 gene expression in the digestive tract.Microbial Biotechnology,2020,13(4):1201-1212.doi:10.1111/1751-7915.13579 Yuqi Wu,Yufei Zheng,Yanan Chen,Gongwen Chen,Huoqing Zheng and Fuliang Hu*.Apis cerana gut microbiota contribute to host health though stimulating host immune system and strengthening host resistance to Nosema ceranae.Royal Society Open Science.2020,7:192100.http://dx.doi.org/10.1098/rsos.192100 Yufei Zheng,Yuqi Wu,Lingchen Tao,Xi Chen,Trevor Joseph Jones,Kai Wang,Fuliang Hu*.Chinese propolis prevents obesity and metabolism syndromes induced by a high fat diet and accompanied by an altered gut microbiota structure in mice.Nutrients,2020,12,959.doi:10.3390/nu12040959 Meng-Meng You,Yi-Chen Liu,Yi-Fan Chen,Yong-Ming Pan,Zhuo-Ning Miao,Yi-Zhen Shi,Juan-Juan Si,Min-Li Chen,Fu-Liang Hu*.Royal jelly attenuates nonalcoholic fatty liver disease by inhibiting oxidative stress and regulating the expression of circadian genes in ovariectomized rats.Journal of Food Biochemistry,2020.doi:10.1111/jfbc.13138 Zheguang Lin,Xiaoling Su,Shuai Wang,Ting Ji,Fu-Liang Hu and Huo-Qing Zheng*.Fumigant toxicity of eleven Chinese herbal essential oils against an ectoparasitic mite(Varroa destructor)of the honey bee(Apis mellifera).Journal of Apicultural Research,2020,59(2):204-210.https://doi.org/10.1080/00218839.2019.1688493 Hongzhuan Xuan*,Wenwen Yuan,Huasong Chang,Minmin Liu,Fuliang Hu*.Anti-inflammatory effects of Chinese propolis in lipopolysaccharide-stimulated human umbilical vein endothelial cells by suppressing autophagy and MAPK/NF-κB signaling pathway.Inflammopharmacology,2019,27:561-571.https://doi.org/10.1007/s10787-018-0533-6 Chen X,Wang S,Xu Y,Gong H,Wu Y*,Chen Y,Hu F,Zheng H.Protective potential of Chinese herbal extracts against microsporidian Nosema ceranae,an emergent pathogen of western honey bees,Apis mellifera L.Journal of Asia-Pacific Entomology,2019.doi:10.1016/j.aspen.2019.08.006 Shuai Wang,Zheguang Lin,Vincent Dietemann,Peter Neumann,Yuqi Wu,Fuliang Hu,and Huoqing Zheng*.Ectoparasitic Mites Varroa underwoodi(Acarina:Varroidae)in Eastern Honeybees,but not in Western Honeybees.Journal of Economic Entomology,112(1),2019,25-32.doi:10.1093/jee/toy288 Shuai Wang,Gongwen Chen,Zheguang Lin,Yuqi Wu,Fuliang Hu,Huoqing Zheng*.Occurrence of multiple honeybee viruses in the ectoparasitic mites Varroa spp.in Apis cerana colonies.Journal of Invertebrate Pathology,2019,166:107225.https://doi.org/10.1016/j.jip.2019.107225 Mengmeng You,Zhuoning Miao,Yongming Pan,Fuliang Hu*.Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.European Journal of Pharmacology,2019,865:172736.doi:10.1016/j.ejphar.2019.172736 Xiasen Jiang,Jing Tian,Yufei Zheng,Yanzheng Zhang,Yuqi Wu,Cuiping Zhang,Huoqing Zheng and Fuliang Hu*.A new propolis type from Changbai Mountains in North-east China:chemical composition,botanical origin and biological activity.Molecules,2019,24,1369.doi:10.3390/molecules24071369 Yongming Pan,Jianqin Xu,Ping Jin,Qinqin Yang,Keyan Zhu,Mengmeng You,Fuliang Hu*and Minli Chen*.Royal jelly ameliorates behavioral deficits,cholinergic system deficiency,and autonomic nervous dysfunction in ovariectomized cholesterol-fed rabbits.Molecules,2019,24,1149.doi:10.3390/molecules24061149 Fu-Liang Hu*,Katarína Bíliková,HervéCasabianca,Gaëlle Daniele,Foued Salmen Espindola,Mao Feng,Cui Guan,Bin Han,Tatiana Krištof Kraková,Jian-Ke Li,Li Li,XingAn Li,JozefŠimúth,Li-Ming Wu,Yu-Qi Wu,Xiao-Feng Xue,Yun-Bo Xue,Kikuji Yamaguchi,ZhiJiang Zeng,Huo-Qing Zheng&Jin-Hui Zhou.Standard methods for Apismellifera royal jelly research,Journal of Apicultural Research,2019,58:2,1-68.doi:10.1080/00218839.2017.1286003 Yongming Pan,Yili Rong,Mengmeng You,Quanxin Ma,Minli Chen,Fuliang Hu*.Royal jelly causes hypotension and vasodilation induced by increasing nitric oxide production.Food Science&Nutrition.2019,7:1361-1370.doi:10.1002/fsn3.970 Yi-zhen Shi,Yi-chen Liu,Yu-fei Zheng,Yi-fan Chen,Juan-juan Si,Min-li Chen,Qi-yang Shou,Huo-qing Zheng,and Fu-liang Hu*.Ethanol extract of Chinese propolis attenuates early diabetic retinopathy by protecting the blood–retinal barrier in streptozotocin-induced diabetic rats.Journal of Food Science,2019,84(2):358-369.doi:10.1111/1750-3841.14435 Yan-Zheng Zhang,Shuai Wang,Yi-Fan Chen,Yu-Qi Wu,Jing Tian,Juan-Juan Si,Cui-Ping Zhang,Huo-Qing Zheng and Fu-Liang Hu*.Authentication of Apis cerana Honey and Apis mellifera Honey Based on Major Royal Jelly Protein 2 Gene.Molecules,2019,24,289.doi:10.3390/molecules 24020289 Mengmeng You,Yongming Pan,Yichen Liu,Yifan Chen,Yuqi Wu,Juanjuan Si,Kai Wang and Fuliang Hu*.Royal jelly alleviates cognitive deficits and b-amyloid accumulation in APP/PS1 mouse model via activation of the cAMP/PKA/CREB/BDNF pathway and inhibition of neuronal apoptosis.Frontiers in Aging Neuroscience.2019,10:428.doi:10.3389/fnagi.2018.00428 Yan-Zheng Zhang,Yi-Fan Chen,Yu-Qi Wu,Juan-Juan Si,Cui-Ping Zhang,Huo-Qing Zheng*,Fu-Liang Hu*.Discrimination of the entomological origin of honey according to the secretions of the bee(Apis cerana or Apis mellifera).Food Research International,2019,116:362-369.https://doi.org/10.1016/j.foodres.2018.08.049 Zheguang Lin,Yao Qin,Paul Page,Shuai Wang,Li Li,Zhengsheng Wen,Fuliang Hu,Peter Neumann,Huoqing Zheng*,Vincent Dietemann.Reproduction of parasitic mites Varroa destructor in original and new honey bee hosts.Ecology and Evolution,2018,8(4):2135-2145. Kai Wang,Xiaolu Jin,Qiangqiang Li,Alexandra Christine Helena Frankland Sawaya,Richard K.Le Leu,Michael A.Conlon,Liming Wu*,and Fuliang Hu*.Propolis from Different Geographic Origins Decreases Intestinal Inflammation and Bacteroides spp.Populations in a Model of DSS-Induced Colitis.Molecular Nutrition and Food Research,2018,62,1800080.doi:10.1002/mnfr.201800080 Hongzhuan Xuan*,Wenwen Yuan,Huasong Chang,Minmin Liu,Fuliang Hu*.Anti_x005f_x001e_inflammatory ffects of Chinese propolis in lipopolysaccharide_x001e_stimulated human umbilical vein endothelial cells by suppressing autophagy and MAPK/NF-κB signaling pathway.Inflammopharmacology,2018.https://doi.org/10.1007/s10787-018-0533-6 Qiang-Qiang Li,Kai Wang,Maria Cristina Marcucci,Alexandra Christine Helena Frankland Sawaya,Lin Hu,Xiao-Feng Xue,Li-Ming Wu,Fu-Liang Hu.Nutrient-rich bee pollen:A treasure trove of active natural metabolites.Journal of Functional Foods,2018,49:472-484 Yufei Zheng,Yuqi Wu,Xi Chen,Xiasen Jiang,Kai Wang and Fuliang Hu*.Chinese propolis exerts anti-proliferation effects in human melanoma cells by targeting NLRP1 inflammatory pathway,inducing apoptosis,cell cycle arrest,and autophagy.Nutrients,2018,10,1170.doi:10.3390/nu 10091170 Yufei Zheng,Kai Wang,Yuqi Wu,Yifan Chen,Xi Chen,Chenyue W.Hu,Fuliang Hu*.Pinocembrin induces ER stress mediated apoptosis and suppresses autophagy in melanoma cells.Cancer Letters,2018,431:31-42 Jing Tan,Xinmi Song,Xiaobin Fu,Fan Wu,Fuliang Hu,Hongliang Li*.Combinatorialmultispectral,thermodynamics,docking and site-directed mutagenesis reveal the cognitive characteristics of honey bee chemosensory protein to plant semiochemical.Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy,2018,201:346-353 Yi-Fan Chen,Meng-Meng You,Yi-Chen Liu,Yi-Zhen Shi,Kai Wang,Yuan-Yuan Lu,Fu-Liang Hu*.Potential protective effect of Trans-10-hydroxy-2-decenoic acid on the inflammation induced by Lipoteichoic acid.Journal of Functional Foods,2018,45:491-498 Meng-Meng You,Yi-Fan Chen,Yong-Ming Pan,Yi-Chen Liu,Jue Tu,Kai Wang,and Fu-Liang Hu*.Royal Jelly Attenuates LPS-Induced Inflammation in BV-2 Microglial Cells through Modulating NF-κB and p38/JNK Signaling Pathways.Mediators of Inflammation,Volume 2018,Article ID 7834381,11 pages.https://doi.org/10.1155/2018/7834381 Yongming Pan,Jianqin Xu,Cheng Chen,Fangming Chen,Ping Jin,Keyan Zhu,Chenyue W.Hu,Mengmeng You,Minli Chen*and Fuliang Hu*.Royal jelly reduces cholesterol levels,ameliorates Ab pathology and enhances neuronal metabolic activities in a rabbit model of Alzheimer’s disease.Frontiers in Aging Neuroscience.2018,10:50.DOI:10.3389/fnagi.2018.00050 Qingyun Diao,Liangxian Sun,Huajun Zheng,Zhijiang Zeng,Shengyue Wang,Shufa Xu,Huoqing Zheng,Yanping Chen,Yuanyuan Shi,Yuezhu Wang,Fei Meng,Qingliang Sang,Lianfei Cao,Fang Liu,Yongqiang Zhu,Wenfeng Li,Zhiguo Li,Congjie Dai,Minjun Yang,Shenglu Chen,Runsheng Chen,Shaowu Zhang,Jay D.Evans,Qiang Huang,Jie Liu,Fuliang Hu*,Songkun Su*&Jie Wu*.Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology.Scientific Reports,2018,(2018)8:822.doi:10.1038/s41598-017-17338-6 Cui-ping Zhang,Xiao-ge Shen,Jia-wei Chen,Xia-sen Jiang,Kai Wang and Fu-liang Hu*.Artepillin C,is it a good marker for quality control of Brazilian green propolis?Natural Product Research,2017,31(20):2441-2444 Xue-Ping Cao,Yi-Fan Chen,Jiang-Lin Zhang,Meng-Meng You,Kai Wang,Fu-Liang Hu*.Mechanisms underlying the wound healing potential of propolis based on its in vitro antioxidant activity.Phytomedicine,2017,34(2017):76-84 Kegan Zhu,Minghui Liu,Zheng Fu,Zhen Zhou,Yan Kong,Hongwei Liang,Zheguang Lin,Jun Luo,Huoqing Zheng,Ping Wan,Junfeng Zhang,Ke Zen,Jiong Chen*,Fuliang Hu*,Chen-Yu Zhang*,Jie Ren*,Xi Chen*.Plant microRNAs in larval food regulate honeybee caste development.PLoS Genetics,13(8):e1006946 Kai Wang,Xiaolu Jin,Mengmeng You,Wenli Tian,Richard K.Le Leu,David L.Topping,Michael A.Conlon*,Liming Wu*and Fuliang Hu*.Dietary propolis ameliorates dextran sulfate sodium-induced colitis and modulates the gut microbiota in rats fed awestern diet.Nutrients,2017,9,875.doi:10.3390/nu9080875 YuQi Wu,HuoQing Zheng*,Miguel Corona,Christian Pirk,Fei Meng,YuFei Zheng&FuLiang Hu*.Comparative transcriptome analysis on the synthesis pathway of honey bee(Apis mellifera)mandibular gland secretions.Scientific Reports,2017,7:4530.DOI:10.1038/s41598-017-04879-z Cuiping Zhang,Xiaoge Shen,Jiawei Chen,Xiasen Jiang,and Fuliang Hu*.Identification of free radical scavengers from Brazilian green propolis using off-line HPLC-DPPH assay and LC-MS.Journal of Food Science,2017,82(7):1602-1607.doi:10.1111/1750-3841.13730 Xiao-Lu Jin,Kai Wang,Qiang-Qiang Li,Wen-Li Tian,Xiao-Feng Xue,Li-Ming Wu*,Fu-Liang Hu.Antioxidant and anti-inflammatory effects of Chinese propolis during palmitic acid-induced lipotoxicity in cultured hepatocytes.Journal of Functional Foods,2017,34:216–223 Hongliang Li*,Jing Tan,Xinmi Song,Fan Wu,Mingzhu Tang,Qiyun Hua,Huoqing Zheng,Fuliang Hu.Sublethal doses of neonicotinoid imidacloprid can interact with honey bee chemosensory protein 1(CSP1)and inhibit its function.Biochemical and Biophysical Research Communications,2017,486(2017):391-397 Liping Sun*,KaiWang,Xiang Xu,Miaomiao Ge,Yifan Chen and Fuliang Hu.Potential Protective Effects of bioactive constituents from Chinese propolis against acute oxidative stress induced by hydrogen peroxide in cardiac H9c2 cells.Evidence-Based Complementary and Alternative Medicine,Volume 2017,Article ID 7074147,10 pages.https://doi.org/10.1155/2017/7074147 Li Li,Zhe-Guang Lin,Shuai Wang,Xiao-Ling Su,Hong-Ri Gong,Hong-Liang Li,Fu-Liang Hu,Huo-Qing Zheng*.The effects of clove oil on the enzyme activity of Varroa destructor Anderson and Trueman(Arachnida:Acari:Varroidae).Saudi Journal of Biological Sciences,2017,24(2017):996-1000 Kai Wang,Xiao-Lu Jin,Xiao-Ge Shen,Li-Ping Sun,Li-Ming Wu,Jiang-Qin Wei,Maria Cristina Marcucci,Fu-Liang Hu*and Jian-Xin Liu.Effects of Chinese propolis in protecting bovine mammary epithelial cells against mastitis pathogens-induced cell damage.Mediators of Inflammation,Volume 2016,Article ID 8028291,12 pages.http://dx.doi.org/10.1155/2016/8028291 Zheguang Lin,Paul Page,Li Li,Yao Qin,Yingying Zhang,Fuliang Hu,Peter Neumann,Huoqing Zheng*,Vincent Dietemann.Go east for better honey bee health:Apis cerana is faster at hygienic behavior than A.mellifera.PLoS One,2016,11(9):e0162647.doi:10.1371/journal.pone.0162647 De-Fang NIU,ChristianW.W.PIRK,Huo-Qing ZHENG,Shun PING,Jin-Hu SHI,Lian-Fei CAO,Fu-Liang HU*.Reproductive traits and mandibular gland pheromone of anarchistic honey bee workers Apis mellifera occurring in China.Apidologie,2016,47:515–526.DOI:10.1007/s13592-015-0396-4 Paul Page,Zheguang Lin,Ninat Buawangpong,Huoqing Zheng*,Fuliang Hu,Peter Neumann,Panuwan Chantawannakul*&Vincent Dietemann.Social apoptosis in honey bee superorganisms.Scientific Reports,2016,6:27210.DOI:10.1038/srep27210 Yi-Fan Chen,Kai Wang,Yan-Zheng Zhang,Yu-Fei Zheng,Fu-Liang Hu*.In Vitro anti-inflammatory effects of three fatty acids from royal jelly.Mediators of Inflammation,2016,Article ID 3583684,11 pages Kai Wang,Xiaolu Jin,Yifan Chen,Zehe Song,Xiasen Jiang,Fuliang Hu*,Michael A.Conlon*and David L.Topping.Polyphenol-Rich Propolis Extracts Strengthen Intestinal Barrier Function by Activating AMPK and ERK Signaling.Nutrients,2016,8,272 Hongliang Li*,Fan Wu,Jing Tan,Kai Wang,Cuiping Zhang,Huoqing Zheng,Fuliang Hu*.Caffeic acid phenethyl ester exhibiting distinctive binding interactionwith human serum albumin implies the pharmacokinetic basis ofpropolis bioactive components.Journal of Pharmaceutical and Biomedical Analysis,2016,122:21-28 Hong-Liang Li*,Cui-Xia Ni,Jing Tan,Lin-Ya Zhang,Fu-Liang Hu*.Chemosensory proteins of the eastern honeybee,Apis cerana:Identification,tissue distribution and olfactory related functional characterization.Comparative Biochemistry and Physiology,Part B,2016,194-195:11-19 Lian-Fei Cao,Huo-Qing Zheng,Christian W.W.Pirk,Fu-Liang Hu,Zi-Wei Xu*.High royal jelly-producing honeybees(Apis mellifera ligustica)(Hymenoptera:Apidae)in China.Journal of Economic Entomology,2016,109(2):510–514 Gong HR,Chen XX,Chen YP,Hu FL,Zhang JL,Lin ZG,Yu JW,Zheng HQ*.Evidence of Apis cerana Sacbrood virus Infection in Apis mellifera.Applied and Environmental Microbiogy.2016,82(8):2256-2262 Xiaolu Jin,Kai Wang,Hongyun Liu*,Fuliang Hu,Fengqi Zhao,Jianxin Liu*.Protection of bovine mammary epithelial cells from hydrogen peroxide-induced oxidative cell damage by resveratrol.Oxidative Medicine and Cellular Longevity,Volume 2016,Article ID 2572175,15 pages.http://dx.doi.org/10.1155/2016/2572175 Ji W,Zhang C,Wei W,Hu F*.The in Vivo antiaging effect of enzymatic hydrolysate from royal jelly in D-galactose induced aging mouse.Journal of Chinese Institute of Food Science and Technology,2016,16(1):18-25 Orlando Yañez,Huo-Qing Zheng*,Xiao-Ling Su,Fu-Liang Hu,Peter Neumann and Vincent Dietemann.Potential for virus transfer between the honey bees Apis mellifera and A.cerana.Journal of Apicultural Research,2015,54(3):179-191 Kai Wang,Lin Hu,Xiao-Lu Jin,Quan-Xin Ma,Maria Cristina Marcucci,Amandio Augusto Lagareiro Netto,Alexandra Christine Helena Frankland Sawaya,Shuai Huang,Wen-Kai Ren,Michael A.Conlon,David L.Topping,Fu-Liang Hu*.Polyphenol-rich propolis extracts from China and Brazil exert anti-inflammatory effects by modulating ubiquitination of TRAF6 during the activation of NF-κB.Journal of Functional Foods,2015,19:464-478 Cui-Ping Zhang,Shun Ping,Kai Wang,Shuai Huang&Fu-Liang Hu*.A survey of the incidence of poplar tree gum in propolis products on the Chinese retail market.Journal of Apicultural Research,54(1):30-35.http://dx.doi.org/10.1080/00218839.2015.1029784 Hongliang Li,Fan Wu,Lei Zhao,Jing Tan,Hongtao Jiang,Fuliang Hu.Neonicotinoid insecticide interact with honeybee odorant-bindingprotein:Implication for olfactory dysfunction.International Journal of Biological Macromolecules,2015,81:624-630 Jianglin Zhang,Xueping Cao,Shun Ping,KaiWang,Jinhu Shi,Cuiping Zhang,Huoqing Zheng,Fuliang Hu*.Comparisons of ethanol extracts of Chinese propolis(poplar type)and poplar gums based on the antioxidant activities and molecular mechanism.Evidence-Based Complementary and Alternative Medicine,Volume 2015,Article ID 307594,15 pages Zheng HQ,Gong HR,Huang SK,Sohr A,Hu FL,Chen YP*.Evidence of the synergistic effect of honey bee pathogens Nosema ceranae and Deformed wing virus.Veterinary Microbiology,2015,177(1-2):1-6 Shuai Huang,Cui-Ping Zhang,Kai Wang,George Q.Li*,Fu-Liang Hu*.Recent advances in the chemical composition of propolis.Molecules,2014,19:19610-19632.doi:10.3390/molecules 191219610 Huixia Zhao,Nenggan Zheng*,Willi A.Ribi,Huoqing Zheng,Lei Xue,Fan Gong,Xiaoxiang Zheng,Fuliang Hu*.Neuromechanism study of insect–machine interface:flight control by neural electrical stimulation.PLoS One,2014,9(11),e113012 Zhang Cui-ping,Huang Shuai,Wei Wen-ting,Ping Shun,Shen Xiao-ge,Li Ya-jing,and Hu Fu-liang*.Development of high-performance liquid chromatographic for quality and authenticity control of Chinese propolis.Journal of Food Science,2014,79(7):C1315-C1322 D.Niu,H.Zheng,M.Corona,Y.Lu,X.Chen,L.Cao,A.Sohr and F.Hu*.Transcriptome comparison between inactivated and activated ovaries of the honey bee Apis mellifera L.Insect Molecular Biology,2014,23(5):668-681.doi:10.1111/imb.12114 Kai Wang,Jianglin Zhang,Shun Ping,Quanxin Ma,Xuan Chen,Hongzhuan Xuan,Jinhu Shi,Cuiping Zhang,Fuliang Hu*.Anti-inflammatory effects of ethanol extracts of Chinese propolis and buds from poplar(Populus×canadensis).Journal of Ethnopharmacology,2014,155:300-311 Shuai Huang,Cui-Ping Zhang,George Q.Li,Yue-Yi Sun,Kai Wang and Fu-Liang Hu*.Identification of catechol as a new marker for detecting propolis adulteration.Molecules,2014,19:10208-10217.doi:10.3390/molecules190710208 Hongzhuan Xuan,Zhen Li,Haiyue Yan,Qing Sang,Kai Wang,Qingtao He,Yuanjun Wang,and Fuliang Hu*.Antitumor activity of Chinese propolis in human breast cancer MCF-7 and MDA-MB-231 cells.Evidence-Based Complementary and Alternative Medicine,Volume 2014,Article ID 280120,11 pages.doi:10.1155/2014/280120 Hongzhuan Xuan,Zhen Li,Jiying Wang,Kai Wang,Chongluo Fu,Jianlong Yuan,Fuliang Hu*.Propolis reduces phosphatidylcholine-specific phospholipase C activity and increasing annexin a7 level in oxidized LDL-stimulated human umbilical vein endothelial cells.Evidence-Based Complementary and Alternative Medicine,Volume 2014,Article ID 465383,9 pages Wen-Ting WEI,Yuan-Qiang HU,Huo-Qing ZHENG,Lian-Fei CAO,Fu-Liang HU*and H.Randall HEPBURN.Geographical influences on content of 10-hydroxy-trans-2-decenoic acid in royal jelly in China.Journal of Economic Entomology,2013,106(5):1958-1963.DOI:http://dx.doi.org/10.1603/EC13035 Hannelie Human*,Robert Brodschneider,Vincent Dietemann,Galen Dively,James D Ellis,Eva Forsgren,Ingemar Fries,Fani Hatjina,Fu-Liang Hu,Rodolfo Jaffé,Annette Bruun Jensen,Angela Köhler,Josef P Magyar,AsliÖzkýrým,Christian W W Pirk,Robyn Rose,Ursula Strauss,Gina Tanner,David R Tarpy,Jozef J M van der Steen,Anthony Vaudo,Fleming Vejsnæs,Jerzy Wilde,Geoffrey R Williams and Huo-Qing Zheng.Miscellaneous standard methods for Apis mellifera research.Journal of Apicultural Research,2013,52(4):1-55.doi:10.3896/IBRA.1.52.4.10 Kai Wang,Shun Ping,Shuai Huang,Lin Hu,Hongzhuan Xuan,Cuiping Zhang and Fuliang Hu*.Molecular mechanisms underlying the in-vitro anti-inflammatory effect of a flavonoids rich ethanol extract from Chinese propolis(poplar type).Evidence-Based Complementary and Alternative Medicine,Volume 2013,Article ID 127672,11 pages Zhang C-P,Ping S,Huang S,Hu F-L*.Research progress in geographic origins,plant origins and chemistry of propolis.Chinese Pharmaceutical Journal,2013,48(22):1889-1892 Wang K,Zhang J-L,Hu F-L*.Research progress in anti-inflammatory activity of propolis and its molecular mechanism.Chinese Traditional and Herbal Drugs,2013,44(16):2321-2329 Lian-Fei CAO,Huo-Qing ZHENG,Fu-Liang HU*,H.R.HEPBURN.Genetic structure of Chinese Apis dorsata population based on microsatellites.Apidologie,2012,43(6):643-651.doi:10.1007/s 13592-012-0139-8 Cui-Ping Zhang,Gang Liu,Fu-Liang Hu*.The hydrolysis of flavonoid glycosides by propolisβ-glucosidase activity.Natural Product Research,2012,26(3):270-273 Huo-Qing Zheng,Wen-Ting Wei,Li-Ming Wu,Fu-Liang Hu*,and Vincent Dietemann.Fast determination of royal jelly freshness by a chromogenic reaction.Journal of Food Science,2012,77(6):S247-S252.doi:10.1111/j.1750-3841.2012.02726.x Orlando Yañez,Huo-Qing Zheng,Fu-Liang Hu,Peter Neumann&Vincent Dietemann.A scientific note on Israeli acute paralysis virus infection of Eastern honeybee Apis cerana and vespine predator Vespa velutina.Apidologie,2012,43(5):587-589,doi:10.1007/s13592-012-0128-y Xuan Chen,Yang Hu,Huoqing Zheng,Lianfei Cao,Defang Niu,Dongliang Yu,Yongqiao Sun,Songnian Hu*,Fuliang Hu*.Transcriptome comparison between honey bee queen-and worker-estined larvae.Insect Biochemistry and Molecular Biology,2012,42:665-673 Huo-Qing ZHENG,Vincent DIETEMANN,Fu-Liang HU*,Robin M.CREWE,Christian W.W.PIRK.A scientific note on the lack of effect of mandible ablation on the synthesis of royal scent by honeybee queens.Apidologie,2012,43:471-473.doi:10.1007/s13592-011-0114-9 Lian-Fei Cao,Huo-Qing Zheng,Xuan Chen,De-Fang Niu,Fu-Liang Hu*and H Randal Hepburn.Multivariate morphometric analyses of the giant honey bees,Apis dorsata F.and Apis laboriosa F.in China.Journal of Apicultural Research,2012,51(3):245-251 Y-J Li,H-Z Xuan,Q-Y Shou,Z-G Zhan,X Lu and F-L Hu*.Therapeutic effects of propolis essential oil on anxiety of restraint stress mice.Human and Experimental Toxicology.2012,31(2):157-165 Lian-Fei Cao,Huo-Qing Zheng,Chen-Yue Hu,Shao-Yu He,Hai-Ou Kuang,and Fu-Liang Hu*.Phylogeography of Apis dorsata(Hymenoptera:Apidae)from China and neighboring Asian areas.Annals of the Entomological Society of America,2012,105(2):298-304. Yajing Li,Minli Chen,Hongzhuan Xuan,and Fuliang Hu*.Effects of encapsulated propolis on blood glycemic control,lipid metabolism,and insulin resistance in type 2 diabetes mellitus rats.Evidence-Based Complementary and Alternative Medicine,Volume 2012(2012),Article ID 981896,8 pages,doi:10.1155/2012/981896 Hongzhuan Xuan,Ruiliang Zhu,Yajing Li,and Fuliang Hu*.Inhibitory effect of Chinese propolis on phosphatidylcholine-specific phospholipase C activity in vascular endothelial cells.Evidence-Based Complementary and Alternative Medicine,Volume 2011,Article ID 985278,8 pages,doi:10.1155/2011/985278 Wei Zhu,Ying-Hua Li,Min-Li Chen and Fu-Liang Hu*.Protective effects of Chinese and Brazilian propolis treatment against hepatorenal lesion in diabetic rats.Human and Experimental Toxicology.2011,30(9):1246-1255.doi:10.1177/0960327110387456 H.-Q.Zheng,F.-L.Hu*and C.W.W.Pirk.Errors in comb building behaviour in Apis cerana cerana that result in entrapped workers.Insectes Sociaux,2011,58(3):413-415 H.-Q.Zheng,F.-L.Hu*and V.Dietemann.Changes in composition of royal jelly harvested at different times:consequences for quality standards.Apidologie,2011,42(1):39-47.doi:10.1051/apido/2010033 ZHENG Neng-gan,CHEN Wei-dong,HU Fu-liang,BAO Li,ZHAO Hui-xia,WANG Kun,ZHENG Xiao-xiang*,WU Zhao-hui.Research progress and challenges on cyborg insect.SCINTIA SINICA Vitae,2011,41(4):259-272.Dio:1360/052010-717 Wei Zhu,Minli Chen,Qiyang Shou,Yinghua Li and Fuliang Hu*.Biological activities of Chinese propolis and Brazilian propolis on streptozotocin-induced type 1 diabetes mellitus in rats.Evidence Based Complementary and Alternative Medicine,2011,Article ID 468529,doi:10.1093/ecam/neq025 Cui-ping Zhang,Huo-qing Zheng,Gang Liu,Fu-liang Hu*.Development and validation of HPLC method for determination of salicin in poplar buds:application for screening of counterfeit propolis.Food Chemistry,2011,127:345–350 Cui-Ping Zhang,Huo-Qing Zheng,and Fu-Liang Hu*.Extraction,partial characterization,and storage stability ofβ-glucosidase from propolis.Journal of Food Science,2011,76(1):75-79 Hongzhuan Xuan,Jing Zhao,Junying Miao,Yajing Li,Yafang Chu,Fuliang Hu*.Effect of Brazilian propolis on human umbilical vein endothelial cell apoptosis.Food and Chemical Toxicology,2011,49:78-85 Huo-Qing Zheng,Vincent Dietemann,Robin M.Crewe,Randall Hepburn,Fu-Liang Hu*,Ming-Xian Yang and Christian W.W.Pirk.Pheromonal predisposition to social parasitism in the honeybee Apis mellifera capensis.Behavioral Ecology,2010,(6):1221-1226.doi:10.1093/beheco/arq131 X.Chen,X.Yu,Y.Cai,H.Zheng,D.Yu,G.Liu,Q.Zhou,S.Hu*and F.Hu*.Next-generation small RNA sequencing for microRNAs profiling in the honey bee Apis mellifera.Insect Molecular Biology,2010,19(6):799-805.doi:10.1111/j.1365-2583.2010.01039.x WU Jie,ZHOU Qun,WU Li-ming,AN Jian-dong,SUN Su-qin*,HU Fu-liang.Study on the identification of six kinds of bee pollens by three step infrared macro Fingerprint method.Spectroscopy and Spectral Analysis,2010,30(2):353-357 Jie Wu,Ji-Lian Li,Wen-Jun Peng and Fu-Liang Hu*.Sensitivities of three bumblebee species to four pesticides applied commonly in greenhouses in China.Insect Science,2010,17,67-72.doi:10.1111/j.1744-7917.2009.01286.x WU Li-ming,ZHOU Qun,ZHAO Jing,SUN Su-qin*,HU Fu-liang.Research on overall assessment of royal jelly freshness by FTIR spectroscopy.Spectroscopy and Spectral Analysis,2009,29(12):3236-3240 Huo-Qing Zheng,Shui-Hua Jin,Fu-Liang Hu*,Christian W W Pirk and Vincent Dietemann.Maintenance and application of multiple queen colonies in commercial beekeeping.Journal of Apicultural Research,2009,48(4):290-295 Huo-Qing Zheng,Shui-Hua Jin,Fu-Liang Hu*and Christian W.W.Pirk.Sustainable multiple queen colonies of honey bees,Apis mellifera ligustica.Journal of Apicultural Research,2009,48(4):284-289 Xiao Feng Xue,Jin Hui Zhou,Li Ming Wu,Liang Hu Fu,Jing Zhao*.HPLC determination of adenosine in royal jelly.Food Chemistry,2009,115:715-719 WU Li-ming,ZHOU Qun,ZHOU Xiao,ZHAO Jing,SUN Su-qin*,HU Fu-liang*.FTIR Assessment of the secondary structure of proteins in royal jelly at different storage conditions.Spectroscopy and Spectral Analysis,2009,29(1):82-87 Vincent Dietemann,Huo-Qing Zheng,Colleen Hepburn,H.Randall Hepburn,Shui-Hua Jin,Robin M.Crewe,Sarah E.Radloff,Fu-Liang Hu*,Christian W.W.Pirk.Self Assessment in Insects:Honeybee Queens Know Their Own Strength.PLoS One,2008,3(1):e1412.doi:10.1371/journal.pone.0001412 Li Y-J,Feng L,Hu F-L*,Zhang T,Chen M-L.Effects of nanometer propolis on metabolism of blood lipid in hyperlipidemic SD rats.Chinese Pharmaceutical Journal,2007,42(12):903-906 Li Y-J,Hu F-L*,Chen M-L.Advances in studies on regulation effects and mechanisms of propolis on glycometabolism and lipid metabolism.Chinese Traditional and Herbal Drugs,2007,38(10):1593-1596 Hu F-L*,Li Y-H,Zhu W,Chen M-L,Ying H-Z.Study on effects and mechanism of propolis on adjuvant arthritis in rats.Chinese Pharmaceutical Journal,2005,40(15):1146-1148 Fuliang Hu,H.R.Hepburn*,Yinghua Li,M.Chen,S.E.Radloff,S.Daya.Effects of ethanol and water extracts of propolis(bee glue)on acute inflammatory animal models.Journal of Ethnopharmacology,2005,100(3):276-283 HU Fuliang,HR.Hepburn*,Hongzhuan Xuan,Minli Chen,S.Daya,S.E.Radloff.Effects of propolis on blood glucose,blood lipid and free radicals in rats with diabetes mellitus.Pharmacological Research,2005,51(2):147-152 Hu F-L*,Li Y-H,Zhu W,Chen M-L,Ying H-Z.Study on effects and mechanism of propolis on the acute lung injury.Chinese Pharmaceutical Journal,2004,39(6):432-434 国际会议论文 INTERNATIONAL CONFERENCE 45th APIMONDIA International Apicultural Congress.September 8th~12th,2019.Montreal,Canada 1.Y.Wu,Y.Zheng,Y.Chen,S.Wang,H.Zheng,F.Hu*.Honey bee gut microbiota regulate the expression of host cytochrome P450 enzymes and contribute to host detoxification ability. 2.M.You,Y.Chen,J.Tian,F.Hu*.Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy. 3.J.Tian,Y.Zhang,J.Si,C.Zhang,H.Zheng,F.Hu*.A survey on the authenticity of Apis cerana cerana honey in Chinese retail market. 4.Y.Chen,Y.Wu,S.Wang,H.Zheng,F.Hu*.The effect of diet on the synthesis ability and gene expression of mandibular gland in honey bee workers(Apis mellifera). The 14th Asian Apicultural Associasion Congress.October 22th–25th,2018.Jakarta,Indonesia 1.Yi-Chen Liu,Meng-Meng You,Yi-Zhen Shi,Yi-Fan Chen,and Fu-Liang Hu*.Royal Jelly Attenuates Non-Alcoholic Fatty Liver Disease and Regulates Expression of Circadian Genes Per1 and Per2 in Ovariectomized Rats. 2.Yi-Zhen Shi,Yi-Chen Liu,Huo-Qing Zheng,and Fu-Liang Hu*.Ethanol Extract of Propolis Attenuates Early Diabetic Retinopathy by Protecting Blood-Retinal Barrier in A Rat Model for Type 1 Diabetes Mellitus. 3.Juan-Juan Si,Huo-Qing Zheng,and Fu-Liang Hu*.Antibacterial and Antioxidative Activity of Chinese Honeys from Different Botanical and Geographical Origins. 4.Meng-Meng You,Yong-Ming Pan,Yi-Chen Liu,Yi-Fan Chen,Quan-Xin Ma,Kai Wang,Fu-Liang Hu*.Royal Jelly Improves Cognitive Deficits and Reduces Alzheimer-associated Pathological changes in APP/PS1 Transgenic Mouse Model. 5.Yan-Zheng Zhang,Yi-Fan Chen,Yu-Qi Wu,Juan-Juan Si,Cui-Ping Zhang,Huo-Qing Zheng*and Fu-Liang Hu*.Discrimination of Apis cerana cerana honey and Apis mellifera ligustica honey by GC-based approach. 6.Shuai Wang,Zhe-Guang Lin,Vincent Dietemann,Peter Neumann,Yu-Qi Wu,Fu-Liang Hu,Huo-Qing Zheng*.A survey of The Ectoparasitic Mite Varroa underwoodi(Acari:Varroidae)in Honey Bee Colonies Across China. 45th APIMONDIA International Apicultural Congress.September 26th~October 4th,2017.Istanbul,Turkey 1.Jiawei Chen,Cuiping Zhang,Xioage Shen,Fuliang Hu*.Spectrum-effect Relationships Between HPLC Fingerprints and DPPH Scavenging Activity of Brazilian Green Propolis. 2.Yifan Chen,Mengmeng You,Yichen Liu,Fuliang Hu*.Potential Protective Effect of 10-HDA on the Inflammation Induced by Lipoteichoic Acid(LTA). 3.Yufei Zheng,Kai Wang,Yuqi Wu,Yifan Chen,Fuliang Hu*.Pinocembrin Triggers A ER Stress Mediated Apoptosis but Suppress the Autophagy via Activation of PI3K Pathway i

学术兼职

中国养蜂学会副理事长 中国蜂产品协会顾问 浙江省蜂业学会理事长 国家蜂产业技术体系产品加工研究室主任 农业部授粉昆虫生物学重点实验室学术委员会主任 杭州蜂业科技创新服务平台工作委员会主任 《中国蜂业》编委 《蜜蜂杂志》编委 《天然产物研究与开发》编委 《经济动物学报》编委 国际蜂蜜委员会(International Honey Commission,IHC)委员 国家自然科学基金委第十三届、十四届生命科学部专家评审组成员 第五届、六届中国兽药典委员会委员 中国农业科学院第八届学术委员会委员 第一届、二届全国蜂产品标准化工作组(SAC/SWG2)委员 浙江省农学会常务理事 浙江省农业产业技术创新与推广服务团队畜牧产业经济动物组组长 浙江省畜禽遗传资源委员会委员 丽水市畜牧产业首席专家 桐庐县蜂产业首席专家 景宁畲族自治县中蜂产业首席科学家

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