方维焕 - 浙江大学 - 动物科学学院

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方维焕二级教授博士生导师收藏完善纠错
浙江大学动物科学学院
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个人简介

主要从事动物疫病和食源性病原微生物致病机制与控制研究；近年来主持国家基金、科技部以及省科技厅重大项目等30余项，在国内外学术刊物上发表论文240余篇，其中155余篇为SCI收录论文；获国家和省部级科技奖7项。教育背景： 1993.11-1996.06：芬兰赫尔辛基大学兽医学院哲学博士 1982.02-1985.01：浙江大学（原浙江农业大学）兽医系硕士 1978.03-1982.01：浙江大学（原浙江农业大学）兽医系学士工作简历 1996.12-至今：浙江大学动物科学学院教授 2006.09-2006.12：美国哈佛大学医学院微生物与分子遗传系访问学者 2001.07-2001.10：丹麦皇家兽医与农业大学访问学者 1996.11-1998.12：美国田纳西大学动物科学系博士后 1992.10-1996.11：浙江农业大学动物科学学院副教授 1988.04-1992.09：浙江农业大学兽医系讲师 1985.02-1988.03：浙江农业大学兽医系助教教学与课程本科生：兽医公共卫生学硕士研究生：1）动物源性食品安全专题；2）预防兽医学专题博士研究生：兽医分子病理学（参与授课）研究与成果 1999年回国以来主持国家和省部级以及企业委托项目30余项，研究内容涉及猪主要传染病发病机制与防控、微生物性食品安全等。出版著作 1.The Bovine Udder and Mastitis，芬兰赫尔辛基大学出版社1995，参编 2.兽医公共卫生学，中国农业出版社，2003第一版，2011第二版，2019第三版，副主编 3.动物性食品卫生学，高等教育出版社2015年第二版，副主编 4.食品检验检疫学，中国农业出版社2007，副主编专利成果 1.猪链球菌2型三重PCR快速检测试剂盒，专利号ZL200610051960.6，2009年12月23日授权。 2.李斯特菌种别及毒力快速检测试剂盒,专利号ZL200710066985.8，2011年1月5日授权。 3.鉴别猪口蹄疫免疫动物与感染动物的ELISA试剂盒，专利号ZL200710164814.9，2011年12月28日授权。 4.携带分子标记的猪瘟病毒C株感染性cDNA载体构建方法，专利号ZL200910155475.7，2012年3月14日授权。 5.基于E2基因的可插入式猪瘟病毒cDNA载体构建及应用，专利号ZL201010197337.8，2012年7月18日授权。 6.抗嗜水气单胞菌免疫球蛋白蛋黄粉包膜即制备方法，专利号ZL200610052057.1，2009年1月7日授权。 7.抗PRRSV-N-IgY抗体制备及在检测PRRSV中的应用，专利号ZL200910153897.0，2012年3月14日授权。 8.用于肉制品非热灭菌的在线式高压脉冲电场处理室，ZL 201110311244.8，2013年9月，发明专利，排名第5。 9.一种指示环境温度变化的视觉标签，2014.9，中国，ZL201210306405.9. 10.分子标记猪瘟病毒弱毒疫苗的构建方法,专利号ZL201610224932.3，授权日2019年10月29日。 11.一株高繁殖能力猪瘟病毒及其构建方法，专利号201810010854.6，授权日2020年6月16日。奖励荣誉 1.鸡传染性法氏囊病基因免疫研究，浙江省科技进步一等奖（2002），第四完成人。 2.集约化猪场猪链球菌病防治技术研究，浙江省科技进步三等奖（2003），第一完成人。 3.食品（茶叶、海产鱼虾）安全关键技术研究与综合示范，浙江省科技进步二等奖（2006），第五完成人。 4.宁波地区重大动物疫病防控关键技术研究，宁波市科学技术进步二等奖（2010），第二完成人。 5.猪肉安全质量控制关键技术研究与示范，浙江省科学技术二等奖（2013），第一完成人。 6.重要食源性人兽共患病原菌的传播生态规律及其防控技术，教育部高等学校科学研究优秀成果奖一等（2013），第二完成人。 7.重要食源性人兽共患病原菌的传播生态规律及其防控技术，国家科技进步二等奖（2017年），第二完成人。学术交流（讲座报告） 1.食源性病原溯源与风险评估，上海市畜牧兽医学会兽医公共卫生学分会成立暨兽医公共卫生国际论坛，2009年9月28-29日，上海。 2.食源性病原溯源技术:PFGE vs MLST，中澳畜牧兽医技术研讨会，2009年9月17-18日，陕西杨凌。 3.我国的肉品安全问题：挑战与机遇，2009ASAS-CAAV亚洲及环太平洋地区动物科学技术大会(Inaugural ASAS-CAAV Asia Pacific Rim Conference)，2009年11月8-10日。 4.单增李斯特菌抗酸应激与感染生物学，中国畜牧兽医学会兽医食品卫生学分会第十一次学术交流会大会报告，2010年4月23-24日，陕西杨凌。 5.单增李斯特菌致病性的分子基础及其在猪肉中污染的控制，中国畜牧兽医学会兽医食品卫生学分会第12届学术研讨会，长春，2012年12月22-24日。 6.副溶血弧菌分子流行病学及其毒力因子研究进展，166th中国工程科技论坛–人兽共患病防控，长春，2013年8月22-24日。 7.单增李斯特菌抗酸应激机制，中国畜牧兽医学会兽医微生物学专业委员会，沈阳，2014年9月12-13日。 8.PCV2感染细胞的内质网应激-自噬-凋亡：独立事件还是因果关系?动物传染病学分会分会第十六次学术会议，2015年9月4-5日，山东济南。 9.生猪屠宰管理与肉品安全和品质维持，中国畜牧兽医学会兽医食品卫生学分会第十三次学术交流会，2015年11月21-22日，北京。 10.我国转型期食源性病原风险评估问题，兽医科技发展国际论坛暨2016上海兽医公共卫生国际论坛，2016年9月21-23日，上海。 11.猪链球菌2型类IV型分泌系统VirD4和折叠酶蛋白PrsA功能研究，第五届全国人畜共患病学术研讨会，2017年4月21-23日，南京。 12.Characterization of the gene locus encoding surface layer proteins in Lactobacillus crispatus isolate ZJ001 having antagonistic activity against enteropathogens.The 6th International Conference on Global Research and Education,September 26-30,2007.Hamamatsu,Japan: 13.Internalin profiling,multilocus sequence typing and virulence assenments suggest evolutionary history of the Listeria monocytogenes-Listeria innocua clade.The 17th International Symposium on Problems of Listeriosis,May 5-8,2010,Porto,Portugal(Universidade Católica Portuguesa). 14.Zoonotic foodborne Listeria monocytogenes:Acid tolerance and infection.The 13rd International Congress of Bacteriology and Applied Microbiology,International Union of Microbiological Societies,September 6-10,2011,Sapporo,Japan. 15.Use of antibiotics in animals and antimicrobial resistance.Joint Symposium on Antimicrobial Resistance,European University Centre at Peking University,Beijing,October 29,2011. 16.PCV2 infection induces ER stress and autophagy in PK-15 cells.The 22nd International Pig Veterinary Society Conference,June 10-13,2012,Jeju,South Korea. 17.Catabolite control protein A and superoxide dismutase of Streptococcus suis type 2 are involved in virulence.The 22nd International Pig Veterinary Society Conference,June 10-13,2012,Jeju,South Korea. 18.PCV2 infection induces autophagy by activating AMPK pathway in PK-15 cells.American Society for Virology 31st Annual Meeting,June 20-25,2012,Wisconsin,Madison,USA. 19.Vibrio parahaemolyticus contains type VI secretion systems I and II that show different functions of adhesion to host cells and autophagy.The 23rd International ICFMH Symposium,Food Micro 2012,September 3-7,2012,Istanbul,Turkey. 20.Management of animal hygiene as an important component of food safety control strategies.The 16th International Congress on Animal Hygiene,May 5-9,2013,Nanjing,CHINA. 21.Peptidyl isomerase PrsA is surface-associated on Streptococcus suis and involved in pyroptosis.The 15th International Congress of Bacteriology&Applied Microbiology,IUMS 2017,July 17-21,2017,Singapore. 22.Development of infrastructure for management of microbial food safety in developing countries:all areas and all things considered–urban or rural.The 5th IUMS Outreach Programme,Advances in Food Safety and Mycotoxins,January 19-20,2017,Yogyakarta,Indonesia. 23.Food Safety Challenges in Developing Asian Countries and Strategies for Improvement.The 4th AFSA International Conference on Food Safety and Food Security,10-12 August 2018,Siem Reap,Cambodia. 24.Advances in the Development of Novel Marker Vaccines against Classical Swine Fever.The 25th International Pig Veterinary Society Conference.June 11-14,2018,Chongqing,CHINA.

研究领域

动物疫病和食源性病原感染生物学微生物性食品安全

近期论文

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1.Liu H,Ye C,Fu H,Yue M,Li X,Fang WH.Stk and Stp1 participate in Streptococcus suis serotype 2 pathogenesis by regulating capsule thickness and translocation of certain virulence factors.Microbial Pathogenesis,2020 Nov 5:104607. 2.Luo H,Zheng J,Chen Y,Wang T,Zhang Z,Shan Y,Xu J,Yue M,Fang WH,Li X.Utility Evaluation of Porcine Enteroids as PDCoV Infection Model in vitro.Frontiers in Microbiology,2020,11:821. 3.Zhou Y,Chen L,Zhang L,Shao C,Sun J,Jiang S,Song Q,Zhou B,Yang Y,Dong W,Yang Y,Wei F,Fang WH,Wang X,Song H.Simultaneous identification of 6 pathogens causing porcine reproductive failure by using multiplex ligation-dependent probe amplification.Transboundary and Emerging Diseases,2020,67(6):2467-2474. 4.Zhu W,Chen Y,He Y,Fang WH,Ying Y,Li Y,Fu Y.Cooperation Mode of Outer Surface and Inner Space of Nanochannel:Separation-Detection System Based on Integrated Nanochannel Electrode for Rapid and Facile Detection of Salmonella.Analytical Chemistry,2020,92(2):1818-1825. 5.Zhang Y,Sun R,Li X,Fang WH.Porcine circovirus 2 induction of ROS is responsible for mitophagy in PK-15 cells via activation of Drp1 phosphorylation.Viruses,2020,12(3):289. 6.Sun R,Sun S,Zhang Y,Zhou Y,Shan Y,Li X,Fang WH.PCV2 induces reactive oxygen species to promote nucleocytoplasmic translocation of the viral DNA binding protein HMGB1 to enhance its replication.Journal of Virology,2020,94(13):e00238-20. 7.Xu H,Wang Y,Han G,Fang WH,He F.Identification of E2 with improved secretion and immunogenicity against CSFV in piglets.BMC Microbiology,2020,20(1):26. 8.Geng SC,Li XL,Fang WH.Porcine circovirus 3 capsid protein induces autophagy in HEK293T cells by inhibiting phosphorylation of the mammalian target of rapamycin.Journal of Zhejiang University Science B,2020,21(7):560-570. 9.Zhang Y,Sun R,Geng S,Shan Y,Li X,Fang WH.Porcine circovirus type 2 induces ORF3-independent mitochondrial apoptosis via PERK activation and elevation of cytosolic calcium.Journal of Virology,2019,93(7):e01784-01718. 10.Cao T,Li X,Xu Y,Zhang S,Wang Z,Shan Y,Sun J,Fang WH,Li X.Npro of classical swine fever virus suppresses type III interferon production by inhibiting IRF1 expression and its nuclear translocation.Viruses.2019,11(11):998. 11.He K,Xin YP,Shan Y,Zhang X,Song HH,Fang WH.Phosphorylation residue T175 in RsbR protein is required for efficient induction of sigma B factor and survival of Listeria monocytogenes under acidic stress.Journal of Zhejiang University Science B.2019,20(8):660-669. 12.Paudyal N,Pan H,Elbediwi M,Zhou X,Peng X,Li X,Fang WH,Yue M.Characterization of Salmonella Dublin isolated from bovine and human hosts.BMC Microbiology,2019,19(1):226. 13.Elbediwi M,Li Y,Paudyal N,Pan H,Li X,Xie S,Rajkovic A,Feng Y,Fang W,Rankin SC,Yue M.Global burden of colistin-resistant bacteria:mobilized colistin resistance genes study(1980-2018).Microorganisms,2019,7(10),pii:E461. 14.Xiao X,Wang W,Zhang J,Liao M,Yang H,Fang W,Li Y.Modeling the Reduction and Cross-Contamination of Salmonella in Poultry Chilling Process in China.Microorganisms,2019,7(10).pii:E448. 15.Liu H,Fu H,Jiang X,Liao X,Yue M,Li X,Fang WH.PrsA contributes to Streptococcus suis serotype 2 pathogenicity by modulating secretion of selected virulence factors.Veterinary Microbiology,2019,236:108375. 16.Wang X,Biswas S,Paudyal N,Pan H,Li X,Fang W,Yue M.Antibiotic resistance in Salmonella Typhimurium isolates recovered from the food chain through National Antimicrobial Resistance Monitoring System Between 1996 and 2016.Frontiers in Microbiology,2019,10:985. 17.Shan Y,Liu Y,Liu Z,Li G,Chen C,Luo H,Chen Y,Guo N,Shi X,Zhang X,Fang W,Li X.Development and application of an indirect enzyme-linked immunosorbent assay using recombinant S1 for serological testing of porcine epidemic diarrhea virus.Canadian Journal of Microbiology,2019,65(5):343-352. 18.Cao T,Wang Z,Li X,Zhang S,Paudyal N,Zhang X,Li X,Fang WH.E2 and E(rns)of classical swine fever virus C-strain play central roles in its adaptation to rabbits.Virus Genes,2019,55(2):238-242. 19.Pan H,Zhou X,Chai W,Paudyal N,Li S,Zhou X,Zhou K,Wu Q,Wu B,Li G,Rajkovic A,Fang W,Rankin SC,Li Y,Xu X,Schifferli DM,Yue M.Diversified sources for human infections by Salmonella enterica serovar newport.Transboundary Emerging Diseases,2019,66(2):1044-1048. 20.Zhou Y,Chen C,Chen Y,Liu Z,Zheng J,Wang T,Luo H,Liu Y,Shan Y,Fang W,Li X.Effect of route of inoculation on innate and adaptive immune responses to porcine epidemic diarrhea virus infection in suckling pigs.Veterinary Microbiology,2019,228:83-92. 21.Cao T,Zhang SN,Li XY,Xu YH,Wang ZH,Chen C,Paudyal N,Li XL,Sun JH,and Fang WH.Classical swine fever virus C-strain with eight mutation sites shows enhanced cell adaptation and protects pigs from lethal challenge.Archives of Virology,2019,164:1619-1628. 22.Geng SC,Luo H,Liu YJ,Chen C,Xu WC,Chen YL,Li XL,Fang WH.Prevalence of porcine circovirus type 3 in pigs in the southeastern Chinese province of Zhejiang.BMC Veterinary Research,2019,15:244. 23.Jiang XW,Yang YK,Zhou JJ,Liu HZ,Liao XY,Luo J,Li XL,Fang WH.Peptidyl isomerase PrsA is surface-associated on Streptococcus suis and offers cross-protection against serotype 9 strain.FEMS Microbiology Letters,2019,366:(2):Fnz002 1-7. 24.Cheng C,Wang H,Ma T,Han X,Yang Y,Sun J,Chen Z,Yu H,Hang Y,Liu F,Fang WH,Jiang L,Cai C,Song H.Flagellar Basal Body Structural Proteins FlhB,FliM,and FliY Are Required for Flagellar-Associated Protein Expression in Listeria monocytogenes.Frontiers in Microbiology,2018,9:208. 25.Paudyal N,Pan H,Liao X,Zhang X,Li X,Fang WH,Yue M.A Meta-Analysis of Major Foodborne Pathogens in Chinese Food Commodities Between 2006 and 2016.Foodborne Pathogens and Disease,2018,15(4):187-197. 26.Xiao X,Pang H,Wang W,Fang WH,Fu Y,Li Y.Modeling Transfer of Vibrio Parahaemolyticus During Peeling of Raw Shrimp.Journal of Food Science,2018,83(3):756-762. 27.Pan H,Paudyal N,Li X,Fang WH,Yue M.Multiple Food-Animal-Borne Route in Transmission of Antibiotic-Resistant Salmonella Newport to Humans.Frontiers in Microbiology,2018,9:23. 28.Gu Y,Zhou Y,Shi X,Xin Y,Shan Y,Chen C,Cao T,Fang WH,Li X.Porcine teschovirus 2 induces an incomplete autophagic response in PK-15 cells.Archives of Virology,2018,163(3):623-632. 29.Paudyal N,Anihouvi V,Hounhouigan J,Matsheka MI,Sekwati-Monang B,Amoa-Awua W,Atter A,Ackah NB,Mbugua S,Asagbra A,Abdelgadir W,Nakavuma J,Jakobsen M,Fang WH.Prevalence of foodborne pathogens in food from selected African countries–A meta-analysis.International Journal of Food Microbiology,2017,249:35–43. 30.Fang LH,Zhou JJ,Fan PC,Yang YK,Shen HX,Fang WH.A serine/threonine phosphatase 1 of Streptococcus suis type 2 is an important virulence factor,Journal of Veterinary Science,2017,18(4):439-447. 31.Yang L,Lu X,Fang WH.Expression and purification of classical swine fever virus E2 protein from Sf9 cells using a modified vector.Biotechnology Letters.2017,39(12):1821-1825. 32.Cheng C,Jiang L,Ma T,Wang H,Han X,Sun J,Yang Y,Chen Z,Yu H,Hang Y,Liu F,Wang B,Fang WH,Huang H,Fang C,Cai C,Freitag N,Song H.Carboxyl-terminal residues N478 and V479 required for the cytolytic activity of Listeriolysin O play a Critical Role in Listeria monocytogenes pathogenicity.Frontiers in Immunology.2017,8:1439. 33.Zhang J,Yin S,Yi D,Zhang H,Li Z,Guo F,Chen C,Fang WH,Wang J.The Brucella melitensis M5-90ΔmanB live vaccine candidate is safer than M5-90 and confers protection against wild-type challenge in BALB/c mice.Microbial Pathogenesis,2017,112:148-155. 34.Tong C,Chen N,Liao X,Yuan X,Sun M,Li X,Fang WH.Continuous passaging of a recombinant C-strain virus in PK-15 cells selects culture-adapted variants that showed enhanced replication but failed to induce fever in rabbits.Journal of Microbiology&Biotechnology.2017,27(9):1701-1710. 35.Cheng C,Dong Z,Han X,Wang H,Jiang L,Sun J,Yang Y,Ma T,Shao C,Wang X,Chen Z,Fang WH,Freitag NE,Huang H,Song H.Thioredoxin A is essential for motility and contributes to host infection of Listeria monocytogenes via redox interactions.Frontiers in Cellular Infection Microbiology.2017,7:287. 36.Fu Y,Shi T,Xu L,Wei W,Lu F,Zhang X,Yuan X,Li J,Lv J,Fang WH.Identification of a novel Hemoplasma species from pigs in Zhejiang province,China.Journal of Veterinary Medical Science.2017,79(5):864-870. 37.Cheng CY,Dong ZM,Han X,Sun J,Wang H,Jiang L,Yang YC,Ma TT,Chen ZW,Yu J,Fang WH,Song,HH.Listeria monocytogenes 10403S arginine repressor ArgR finely tunes arginine metabolism regulation under acidic conditions.Frontiers in Microbiology,2017,8:145. 38.Zhou YS,Gu YX,Qi BZ,Zhang YK,Li XL,Fang WH.Porcine circovirus type 2b capsid protein induces unfolded protein response with subsequent activation of apoptosis.Journal of Zhejiang University-Science B,2017,18(4):316–323. 39.Jiang XW,Yang YK,Zhou JJ,Zhu LX,Gu YX,Zhang XY,Li XL,Fang WH.Roles of the Putative Type IV-like Secretion System Key Component VirD4 and PrsA in Pathogenesis of Streptococcus suis Type 2.Frontiers in Cellular&Infection Microbiology,2016,6:172. 40.Zhou YS,Liang Q,Li WF,Gu YX,Liao X,Fang WH,Li XL.Characterization and functional analysis of toll-like receptor 4 in Chinese soft-shelled turtle Pelodiscus sinensis,Developmental&Comparative Immunology,2016,63:128-135. 41.Xue YY,Shi MT,Tu F,Wu CQ,Ren GP,Wang XJ,Fang WH,Song HH,Yang MH.Redox pathway sensing bile salts activates virulence gene expression in Vibrio cholerae.Molecular Microbiology,2016,102(5):909-924. 42.Liao X,Wang ZH,Cao T,Tong C,Geng SC,Gu YX,Zhou YS,Li XL,Fang WH.Hypervariable antigenic region 1 of classical swine fever virus E2 protein impacts antibody neutralization.Vaccine,2016,34(33):3723-3730. 43.Liang Q,Li WF,Guo NN,Tong C,Zhou YS,Fang WH,Li XL.Identification and functional analysis of interleukin-1βin the Chinese soft-shelled turtle Pelodiscus sinensis.Genes,2016,7(5):18. 44.Gu YX,Qi BZ,Zhou YS,Jiang XW,Zhang X,Li XL,Fang WH.Porcine Circovirus Type 2 Activates CaMMKβto Initiate Autophagy in PK-15 Cells by Increasing Cytosolic Calcium.Viruses,2016,8(5):135 45.Jiang XW,Yang YK,Zhu LX,Gu YX,Shen HX,Shan Y,Li XL,Wu JS,Fang WH.Live Streptococcus suis type 5 strain XS045 provides cross-protection against infection by strains of types 2 and 9.Vaccine,2016,34(51):6529–6538. 46.Wang XD,Shao CY,Wang LY,Li QJ,Song HH,Fang WH.The viral non-structural protein 1 alpha(Nsp1a)inhibits p53 apoptosis activity by increasing murine double minute 2(mdm2)expression in porcine reproductive and respiratory syndrome virus(PRRSV)early-infected cells.Veterinary Microbiology,2016,184:73-79. 47.Shan Y,Zhang YK,Zhuo XH,Li XL,Peng JR,Fang WH.Matrix metalloproteinase-9 plays a role in protecting zebrafish from lethal infection with Listeria monocytogenes by enhancing macrophage migration.Fish&Shellfish Immunology,2016,54,179-187. 48.Zhou YS,Qi BZ,Gu YX,Xu F,Du HH,Li XL,Fang WH.Porcine circovirus 2 deploys PERK pathway and GRP78 for its enhanced replication in PK-15 cells.Viruses,2016,8(2):56. 49.Xia Y,Xin YP,Li XL,Fang WH.To modulate survival under secondary stress conditions,Listeria monocytogenes 10403S employs RsbX to down-regulateσB activity in the post-stress recovery stage or stationary phase.Applied&Environmental Microbiology,2016,82(4):1126-1135. 50.Fang C,Cao T,Shan Y,Xia Y,Xin YP,Cheng CY,Song HH,Bowman J,Li XL,Zhou X,Fang WH.Comparative genomic analysis teveals that the 20K and 38K prophages in Listeria monocytogenes serovar 4a strains Lm850658 and M7 contribute to genetic diversity but not to virulence.Journal of Microbiology&Biotechnology,2016,26(1):197-206. 51.Fang C,Shan Y,Cao T,Xia Y,Xin YP,Cheng CY,Song HH,Li XL,Fang WH.Prevalence and virulence characterization of Listeria monocytogenes in chilled pork in Zhejiang province,China.Foodborne Pathogens and Disease,2016,13(1):8-12. 52.Sun Y,Ke H,Han M,Chen N,Fang WH,Yoo D.Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus Suppresses Both MAVS and RIG-I Expression as One of the Mechanisms to Antagonize Type I Interferon Production.PLoS One.2016,11(12):e0168314. 53.Cheng CY,Wang XD,Dong Z,Shao CY,Yang Y,Fang WH,Fang CC,Wang H,Yang MH,Jiang LL,Zhou X,Song HH.Aminopeptidase T of M29 Family Acts as A Novel intracellular virulence factor for Listeria monocytogenes infection.Scientific Report.2015,5:17370. 54.Zhang X,Wang X,Sun MJ,Zhang X,Song HH,Yan Y,Sun J,Li XL,Fang WH.A magnetic nanoparticle-based enzyme-linked immunosorbent assay for sensitive quantification of zearalenone in cereal and feed samples.Toxins(Basel),2015,7(10):4216-31. 55.Zhang X,Sun MJ,Kang Y,Xie H,Wang X,Song HH,Li XL,Fang WH.Identification of a high-affinity monoclonal antibody against ochratoxin A and its application inenzyme-linked immunosorbent assay.Toxicon,2015,106:89-96. 56.Wang L,Wang R,Kong BW,Jin S,Ye K,Fang WH,Li YB.B cells using calcium signaling for specific and rapid detection of Escherichia coli O157:H7.Scientific Report,2015,5:10598. 57.Shan Y,Fang C,Cheng CY,Wang Y,Peng JR,Fang WH.Immersion infection of germ-free zebrafish with Listeria monocytogenes induces transient 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学术兼职

1999 - 2009：浙江大学动物科学学院副院长 2000 - 2019：浙江大学动物预防医学研究所所长 2004 - 2015：浙江省动物预防医学重点实验室主任 2011 - 至今：国际食品微生物与卫生委员会执行委会会委员 2008 - 2016：中国畜牧兽医学会常务理事 2005 - 至今：中国畜牧兽医学会兽医食品卫生学分会副理事长 2014 - 2020：浙江省畜牧兽医学会理事长 2002 - 至今：International Journal of Food Microbiology 编委 2008 - 2011：International Journal of Food Microbiology 编辑 2005 - 至今：Foodborne Pathogens and Disease 编委 1999 - 至今：《畜牧兽医学报》编委 2005 - 至今：《微生物学报》编委 2005 - 至今：《中国兽医科学》编委

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